نتائج البحث - "Pedro E. Cruz"

1

دورية أكاديمية

Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance

المؤلفون: Cara L. Croft, Giavanna Paterno, Ava R. Vause, Lyla A. Rowe, Daniel H. Ryu, Marshall S. Goodwin, Corey A. Moran, Pedro E. Cruz, Benoit I. Giasson, Todd E. Golde

المصدر: npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-12 (2022)

مصطلحات موضوعية: Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2373-8057

URL الوصول: https://doaj.org/article/e2074e1cbc8644f181214b5c8eb0e8eb

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2

دورية أكاديمية

Il-10 signaling reduces survival in mouse models of synucleinopathy

المؤلفون: Samuel G. Cockey, Karen N. McFarland, Emily J. Koller, Mieu M. T. Brooks, Elsa Gonzalez De La Cruz, Pedro E. Cruz, Carolina Ceballos-Diaz, Awilda M. Rosario, Yona R. Levites, David R. Borchelt, Todd E. Golde, Benoit I. Giasson, Paramita Chakrabarty

المصدر: npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2373-8057

URL الوصول: https://doaj.org/article/7d31e8435b0349f4ac0351ba14562121

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3

دورية أكاديمية

Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila

المؤلفون: Lorena De Mena, Michael A. Smith, Jason Martin, Katie L. Dunton, Carolina Ceballos-Diaz, Karen R. Jansen-West, Pedro E. Cruz, Kristy D. Dillon, Diego E. Rincon-Limas, Todd E. Golde, Brenda D. Moore, Yona Levites

المصدر: Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: Alzheimer’s disease, Amyloid plaques, Cognitive impairment, Drosophila, Fruit fly, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13195-020-00698-z; https://doaj.org/toc/1758-9193

URL الوصول: https://doaj.org/article/4f306eef2ef84838870e90a91c5e001d

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4

دورية أكاديمية

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS

المصدر: Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Adeno-associated virus, Capsid pseudo-type, AAV production, Gene delivery, Central nervous system, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13024-020-00361-z; https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/2a178227546947689b7deca1eadc1b03

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5

Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes

المؤلفون: Veronica O’Neal, Benoit I. Giasson, Olga Sinyavskaya, Todd E. Golde, Peter Davies, Marshall S. Goodwin, Pedro E. Cruz, Franklin Burg, Jada Lewis, Yona Levites, Carolina Ceballos-Diaz

المصدر: Molecular Therapy

مصطلحات موضوعية: medicine.medical_treatment, iB, medicine.disease_cause, Intrabody, scFv, Mice, 0302 clinical medicine, Drug Discovery, Adeno-associated virus, 0303 health sciences, Secretory Pathway, phosphorylation, Neurodegeneration, neurodegeneration, Neurodegenerative Diseases, Alzheimer's disease, Dependovirus, Combined Modality Therapy, Cell biology, intrabody, Treatment Outcome, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, Tauopathy, immunotherapy, Antibody, Intracellular, single-chain variable fragments, Genetic Vectors, Mice, Transgenic, tau Proteins, adeno-associated virus, Biology, 03 medical and health sciences, mental disorders, Genetics, Extracellular, medicine, Animals, Molecular Biology, 030304 developmental biology, Pharmacology, tauopathy, Immunotherapy, Genetic Therapy, medicine.disease, Disease Models, Animal, biology.protein, Single-Chain Antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbfb4c45d2c988b9042e56f5c23a6dc
http://europepmc.org/articles/PMC7854277

6

Targeting aggregated tau turnover as a therapeutic strategy

المؤلفون: Cara L Croft, Marshall S Goodwin, Daniel H Ryu, Christian B Lessard, Giancarlo Tejeda, Marc Marrero, Ava Vause, Giavanna Paterno, Pedro E Cruz, Jada Lewis, Benoit Giasson, Todd E Golde

المصدر: Alzheimer's & Dementia. 17

مصطلحات موضوعية: Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a7393a01e16babcc85b9105472dcc667
https://doi.org/10.1002/alz.056366

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7

Downregulation of the human peripheral myelin protein 22 gene by miR-29a in cellular models of Charcot–Marie–Tooth disease

المؤلفون: Jacquelyn Serfecz, Lucia Notterpek, Peter C. Turner, Hannah Bazick, Christopher J. Fields, Pedro E. Cruz, Rolf Renne, Mohammed Omar Al Salihi

المصدر: Gene Therapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c224ae1546bf9cacc16ae9d9dbae53
http://europepmc.org/articles/PMC6920087

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8

An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, endocrine system, Hypothalamo-Hypophyseal System, Corticotropin-Releasing Hormone, Immunology, Neuropeptide, Pituitary-Adrenal System, Myostatin, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Corticotropin-releasing hormone, 0302 clinical medicine, law, Corticosterone, Stress, Physiological, Cell Line, Tumor, Immunology and Allergy, Medicine, Animals, Humans, Receptor, Research Articles, Mice, Inbred BALB C, biology, business.industry, Gene Expression Profiling, Brief Definitive Report, Antibodies, Monoclonal, 3. Good health, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Phenotype, chemistry, biology.protein, Suppressor, FKBP5, business, 030217 neurology & neurosurgery, Hypothalamic–pituitary–adrenal axis, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe3b02ddf6c1d5f584f18b771cc69fe
http://europepmc.org/articles/PMC6829597

9

rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies

المؤلفون: Wen Lang Lin, Kevin H. Strang, Brittany M. Woody, Paramita Chakrabarty, Yona Levites, Edgardo Rodriguez-Lebron, Pedro E. Cruz, Todd E. Golde, Carolina Ceballos-Diaz, Michael DeTure, Daniel Ryu, Benoit I. Giasson, Dennis W. Dickson, Cara L. Croft

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Technical Advances, viruses, Transgene, Immunology, Drug Evaluation, Preclinical, Gene Expression, Mice, Transgenic, tau Proteins, Biology, medicine.disease_cause, 03 medical and health sciences, Organ Culture Techniques, 0302 clinical medicine, Slice preparation, Alzheimer Disease, Transduction, Genetic, medicine, Animals, Humans, Immunology and Allergy, Transgenes, Adeno-associated virus, Research Articles, Neurons, Mice, Inbred C3H, Lewy body, Microglia, Neurodegeneration, Brain, Parkinson Disease, Dependovirus, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Mutation, alpha-Synuclein, Tauopathy, Microorganisms, Genetically-Modified, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e789211d103e514ff64a9c16e7bce86
https://doi.org/10.1084/jem.20182184

10

Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy

المؤلفون: Dennis W. Dickson, Baxter Bramblett, Karen N. McFarland, Nathan D. Price, Mariet Allen, Todd E. Golde, Nilufer Ertekin-Taner, Cory C. Funk, Xue Wang, Hong-Dong Li, Xufei Liu, Max Robinson, Pedro E. Cruz, Daniel Ryu, Paramita Chakrabarty, Yona Levites, Veronica O’Neal, Thomas B. Ladd, Minerva M. Carrasquillo

المصدر: Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: 0301 basic medicine, Amyloid, Transgene, medicine.medical_treatment, Priming (immunology), Inflammation, Mice, Transgenic, Biology, Adenoassociated virus, Il6, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, 0302 clinical medicine, Alzheimer Disease, RNA seq, medicine, Animals, Humans, RC346-429, Receptor, Molecular Biology, Il10, Temporal cortex, Innate immune system, Amyloid beta-Peptides, Interleukin-6, RC952-954.6, Immunization, Passive, Antibodies, Monoclonal, Immunotherapy, Immunity, Innate, Interleukin-10, 030104 developmental biology, Gliosis, Geriatrics, Immunology, Neurology. Diseases of the nervous system, Neurology (clinical), medicine.symptom, Alzheimer’s disease, 030217 neurology & neurosurgery, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca48d705790bc7992dd7baad798eae5
https://pubmed.ncbi.nlm.nih.gov/33957936

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