المؤلفون: Brown, Elizabeth A, Minnich, Anne, Sanyal, Arun J, Loomba, Rohit, Du, Shuyan, Schwarz, John, Ehman, Richard L, Karsdal, Morten, Leeming, Diana J, Cizza, Giovanni, Charles, Edgar D

المصدر: JHEP Reports. 5(4)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Liver Disease, Clinical Research, Hepatitis, Clinical Trials and Supportive Activities, 4.1 Discovery and preclinical testing of markers and technologies, 4.2 Evaluation of markers and technologies, Detection, screening and diagnosis, Oral and gastrointestinal, Cancer, Good Health and Well Being, fibroblast growth factor 21, non-alcoholic steatohepatitis, liver fibrosis, steatosis, precirrhotic NASH, SomaSignal, ALT, alanine aminotransferase, APRI, AST-to-platelet ratio index, AST, aspartate aminotransferase, CK-18 M30, caspase-cleaved cytokeratin 18, ELF, enhanced liver fibrosis, FGF21, fibroblast growth factor 21, FIB-4, fibrosis-4 index, MRE, magnetic resonance elastography, MRI-PDFF, MRI-proton density fat fraction, NAFLD, non-alcoholic fatty liver disease, NAS, NAFLD activity score, NASH, non-alcoholic steatohepatitis, P3NP, procollagen-3 N-terminal propeptide, PC3X, crosslinked ADAMTS-2-released N-terminal type III collagen propeptide, PGBF, pegbelfermin, PRO-C3, monomeric ADAMTS-2-released N-terminal type III collagen propeptide, T2D, type 2 diabetes, TG, triglycerides, TIMP-1, tissue inhibitor of metalloproteinases type 1, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9b86q751

المؤلفون: Yangguang Lu, Bohuai Yu, Yiran Bu, Jialing Lou, Yan Jin

المصدر: Frontiers in Medicine, Vol 11 (2024)

مصطلحات موضوعية: non-alcoholic steatohepatitis, Pegbelfermin, BMS-986036, fibroblast growth factor 21, transaminase reduction, dose-response meta-analysis, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1293336/full; https://doaj.org/toc/2296-858X

URL الوصول: https://doaj.org/article/444a1fe2e8d04d4d982809293cd80daf

المؤلفون: Elizabeth A. Brown, Anne Minnich, Arun J. Sanyal, Rohit Loomba, Shuyan Du, John Schwarz, Richard L. Ehman, Morten Karsdal, Diana J. Leeming, Giovanni Cizza, Edgar D. Charles

المصدر: JHEP reports : innovation in hepatology, vol 5, iss 4

مصطلحات موضوعية: ALT, enhanced liver fibrosis, Oral and gastrointestinal, Hepatitis, FGF21, aspartate aminotransferase, steatosis, Immunology and Allergy, T2D, PRO-C3, triglycerides, APRI, liver fibrosis, Cancer, screening and diagnosis, Liver Disease, Gastroenterology, NASH, magnetic resonance elastography, Detection, MRE, PC3X, FIB-4, TG, non-alcoholic steatohepatitis, type 2 diabetes, 4.2 Evaluation of markers and technologies, fibrosis-4 index, CK-18 M30, alanine aminotransferase, Chronic Liver Disease and Cirrhosis, Clinical Trials and Supportive Activities, fibroblast growth factor 21, precirrhotic NASH, NAFLD activity score, SomaSignal, pegbelfermin, MRI-proton density fat fraction, TIMP-1, Clinical Research, NAFLD, AST-to-platelet ratio index, Internal Medicine, P3NP, AST, Hepatology, procollagen-3 N-terminal propeptide, crosslinked ADAMTS-2-released N-terminal type III collagen propeptide, non-alcoholic fatty liver disease, caspase-cleaved cytokeratin 18, 4.1 Discovery and preclinical testing of markers and technologies, monomeric ADAMTS-2-released N-terminal type III collagen propeptide, ELF, Good Health and Well Being, NAS, PGBF, Digestive Diseases, MRI-PDFF, tissue inhibitor of metalloproteinases type 1

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387fc65f27fe0d437ddb7fd2988e80a9
https://escholarship.org/uc/item/9b86q751

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المؤلفون: Ivo P van de Peppel, Johan W. Jonker, Cristy R C Verzijl, Dicky Struik

المساهمون: Center for Liver, Digestive and Metabolic Diseases (CLDM)

المصدر: Expert opinion on investigational drugs, 29(2), 1-9. Taylor & Francis Ltd

مصطلحات موضوعية: 0301 basic medicine, BETA-KLOTHO, medicine.medical_specialty, Cirrhosis, FGF21, PATHOGENESIS, digestive system, Gastroenterology, Polyethylene Glycols, 03 medical and health sciences, Liver disease, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, NAFLD, Internal medicine, Nonalcoholic fatty liver disease, Animals, Humans, Medicine, Pharmacology (medical), Obesity, CONFERS SUSCEPTIBILITY, FATTY LIVER-DISEASE, BARIATRIC SURGERY, Pharmacology, business.industry, Pegbelfermin, Fatty liver, NASH, nutritional and metabolic diseases, REDUCES FEATURES, Drugs, Investigational, MOUSE MODEL, ASSOCIATION, General Medicine, medicine.disease, digestive system diseases, Fibroblast Growth Factors, Clinical trial, BODY-WEIGHT, 030104 developmental biology, 030220 oncology & carcinogenesis, Disease Progression, Insulin Resistance, Steatosis, business, Liver cancer

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7937c2b05feca435096f3f2242a5b671
https://doi.org/10.1080/13543784.2020.1708898

المؤلفون: Petia Shipkova, Giridhar S. Tirucherai, Arun J. Sanyal, Diane E. Shevell, Benjamin E. Decato, Colleen A. McNaney, Yi Luo, Edgar D. Charles, Abraham Apfel

المصدر: JHEP Reports

مصطلحات موضوعية: GCDCA, glyco-chenodeoxycholic acid, C4, 7α-hydroxy-4-cholesten-3-one, Deoxycholic acid, FGF21, fibroblast growth factor 21, AST, aspartate aminotransferase, PGBF, pegbelfermin, Gastroenterology, chemistry.chemical_compound, FGF21, QD, once daily, Chenodeoxycholic acid, Nonalcoholic fatty liver disease, Immunology and Allergy, LCA, lithocholic acid, CA, cholic acid, Bile acid, LC, liquid chromatography, Fatty liver, baiH, 7β-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductase, BA, bile acid, Research Article, TCDCA, tauro-chenodeoxycholic acid, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TDCA, tauro-deoxycholic acid, hdhA, 7-alpha-hydroxysteroid dehydrogenase, GUDCA, glyco-ursodeoxycholic acid, Bile salt hydrolase, CYP7A1, cytochrome P450 7A1, PEGylated, polyethylene glycol-conjugated, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, FXR, farnesoid X receptor, TCA, tauro-cholic acid, Internal medicine, 7α-Hydroxy-4-cholesten-3-one, ALT, alanine aminotransferase, Internal Medicine, medicine, GCA, glyco-cholic acid, C4, Hepatology, business.industry, T2DM, type 2 diabetes mellitus, medicine.disease, GDCA, glyco-deoxycholic acid, QW, once weekly, chemistry, DCA, deoxycholic acid, MS, mass spectrometry, BSH, bile salt hydrolase, baiCD, 7α-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductase, PRO-C3, N-terminal type III collagen propeptide, HbA1c, glycated haemoglobin, Microbiome, HFF, hepatic fat fraction, Steatosis, Steatohepatitis, business, ApoA1, apolipoprotein A1, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c523b47362c4cc87193b195c73edfb6d
https://pubmed.ncbi.nlm.nih.gov/34977519

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