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1دورية أكاديمية
المؤلفون: Pei-Li Yao, Jeremy Peavey, Goldis Malek
المصدر: International Journal of Molecular Sciences, Vol 21, Iss 8, p 2889 (2020)
مصطلحات موضوعية: nuclear receptors, angiogenesis, wet age-related macular degeneration, proliferative diabetic retinopathy, inflammation, Biology (General), QH301-705.5, Chemistry, QD1-999
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Pei-Li Yao, Parmar, Vipul M., Choudhary, Mayur, Malek, Goldis
المصدر: Proceedings of the National Academy of Sciences of the United States of America; 7/12/2022, Vol. 119 Issue 28, p1-12, 44p
مصطلحات موضوعية: MACULAR degeneration, RHODOPSIN, EPITHELIAL-mesenchymal transition, STEM cell donors, ORAL drug administration, PHENOTYPES
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5LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target
المؤلفون: Ebraheim N. Ismail, Rajendra S. Apte, Steven Nusinowitz, James T. Handa, Jeffrey W. Ruberti, Peter Tontonoz, Faryan Tayyari, Goldis Malek, Michael E. Boulton, Mayur Choudhary, Pei-Li Yao, Roxana A. Radu
المصدر: JCI insight, vol 5, iss 1
مصطلحات موضوعية: Male, 0301 basic medicine, Aging, genetic structures, Retinal Pigment Epithelium, Neurodegenerative, Inbred C57BL, Mouse models, Eye, Mice, Macular Degeneration, 0302 clinical medicine, 80 and over, 2.1 Biological and endogenous factors, Medicine, Aetiology, Liver X Receptors, Aged, 80 and over, Mice, Knockout, General Medicine, Middle Aged, Phenotype, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, lipids (amino acids, peptides, and proteins), medicine.symptom, Research Article, Adult, Adolescent, Knockout, Inflammation, Therapeutics, Retina, Proinflammatory cytokine, Young Adult, 03 medical and health sciences, Downregulation and upregulation, Animals, Humans, Retinopathy, Liver X receptor, Eye Disease and Disorders of Vision, Aged, Retinal pigment epithelium, Animal, business.industry, Neurosciences, Endothelial Cells, Lipid metabolism, Macular degeneration, medicine.disease, eye diseases, Mice, Inbred C57BL, Disease Models, Animal, Ophthalmology, 030104 developmental biology, Nuclear receptor, Disease Models, Cancer research, sense organs, Transcriptome, Digestive Diseases, business, Genome-Wide Association Study
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8ab067c5a1f6a00b003ac61b2ca305
https://doi.org/10.1172/jci.insight.131928 -
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المؤلفون: Mayur Choudhary, Pei-Li Yao, Goldis Malek
المصدر: Topics in Medicinal Chemistry ISBN: 9783030566180
مصطلحات موضوعية: Drug discovery, business.industry, Age related, medicine, Disease, Macular degeneration, Bioinformatics, medicine.disease, business, eye diseases, Unmet needs
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2d9e35214e4cbbbf036046b42ceced22
https://doi.org/10.1007/7355_2020_93 -
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المؤلفون: Elizabeth Ola, Christina Lee, Bokai Zhu, Ashley L. Wagner, Boo Hyon Kang, Frank J. Gonzalez, Michael G. Borland, Jeffrey M. Peters, Prajakta P. Albrecht, Pei-Li Yao, Brooke E. Shannon, Ellen M. Kehres, Amanda M. Pritzlaff, Gavin P. Robertson
المصدر: Toxicological Sciences. 159:436-448
مصطلحات موضوعية: 0301 basic medicine, Skin Neoplasms, DNA damage, Peroxisome Proliferator-Activated Receptors, Mice, Nude, Apoptosis, ROLE OF PPARβ/δ AND PPARγ IN MELANOMA TUMORIGENICITY, Biology, Ligands, Toxicology, medicine.disease_cause, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Cell Adhesion, medicine, Animals, Humans, Receptor, Melanoma, S phase, Cell Proliferation, Inflammation, Cell growth, Cell Cycle, Cell cycle, Cell biology, 030104 developmental biology, Cell culture, 030220 oncology & carcinogenesis, Cancer research, Heterografts, Carcinogenesis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e7da6c22064af752361602b069b02f
https://doi.org/10.1093/toxsci/kfx147 -
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المؤلفون: Frank J. Gonzalez, Jeffrey M. Peters, Jose L. Morales, Pei-Li Yao
المصدر: Immunology. 150:456-467
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Immunology, Peroxisome proliferator-activated receptor, Bone Marrow Cells, Inflammation, Immunoglobulin E, Proinflammatory cytokine, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Immunology and Allergy, Mast Cells, PPAR delta, Extracellular Signal-Regulated MAP Kinases, Receptor, PPAR-beta, Cells, Cultured, Mice, Knockout, chemistry.chemical_classification, biology, Receptors, IgE, Kinase, Cell Differentiation, Original Articles, Mast cell, Cell biology, Mice, Inbred C57BL, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Cytokine, chemistry, biology.protein, Cytokines, Female, Inflammation Mediators, medicine.symptom, Signal Transduction, 030215 immunology
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المؤلفون: Liping Chen, Rolf Müller, Tomasz P. Dobrzański, Jeffrey M. Peters, Bokai Zhu, Frank J. Gonzalez, Boo-Hyon Kang, Pei-Li Yao
المصدر: Molecular Carcinogenesis. 56:1472-1483
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cellular differentiation, Retinoic acid, Mice, Nude, Peroxisome proliferator-activated receptor, Tretinoin, Biology, Article, Neuroblastoma, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, medicine, Animals, Humans, PPAR delta, PPAR-beta, Molecular Biology, chemistry.chemical_classification, Retinoic Acid Receptor alpha, SOXB1 Transcription Factors, PTEN Phosphohydrolase, Cell Differentiation, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Cell culture, Retinoic acid receptor alpha, 030220 oncology & carcinogenesis, Cancer research, Female, Tumor Suppressor Protein p53, Signal transduction, medicine.drug
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المؤلفون: Gayathri Balandaram, Gary H. Perdew, Albert J. Fornace, Takayuki Koga, Frank J. Gonzalez, Iain A. Murray, Maryam Goudarzi, Jeffrey M. Peters, Pei-Li Yao
المصدر: Journal of Biological Chemistry. 291:25255-25263
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Kupffer Cells, Sp1 Transcription Factor, Peroxisome proliferator-activated receptor, Biology, Biochemistry, Gene Expression Regulation, Enzymologic, Mice, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Constitutive androstane receptor, medicine, Animals, Gene Regulation, PPAR delta, Cytochrome P450 Family 2, Promoter Regions, Genetic, Liver Diseases, Alcoholic, PPAR-beta, Molecular Biology, Transcription factor, Mice, Knockout, Regulation of gene expression, Liver injury, chemistry.chemical_classification, Sp1 transcription factor, Ethanol, Cell Biology, medicine.disease, Cell biology, 030104 developmental biology, Endocrinology, Liver, chemistry, 030220 oncology & carcinogenesis, Steroid Hydroxylases, Hepatocytes, Peroxisome proliferator-activated receptor delta, Aryl Hydrocarbon Hydroxylases, Signal transduction, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb4d5d0cc457a8ea37f69940eca827a
https://doi.org/10.1074/jbc.m116.755447