يعرض 1 - 2 نتائج من 2 نتيجة بحث عن '"Pernilla Ståhlberg"', وقت الاستعلام: 1.09s تنقيح النتائج
  1. 1
    Discovery of N-(1-adamantyl)-2-(4-alkylpiperazin-1-yl)acetamide derivatives as T-type calcium channel (Cav3.2) inhibitors

    المؤلفون: Antonio Llinas, Fredrik Thorstensson, Emma Lindhardt, Ågot Högberg, Kristina Nilsson, Anders Lindqvist, Annika Åstrand, Göran Duker, Victoria Ullah, Gavin O'Mahony, Qing-Dong Wang, Pernilla Ståhlberg, Nidhal Selmi, Laurent Knerr, Fabrizio Giordanetto

    المصدر: Bioorganic & Medicinal Chemistry Letters. 21:5557-5561

    مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Calcium Channels, T-Type, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Acetamides, Drug Discovery, Animals, Humans, Molecular Biology, Antihypertensive Agents, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Calcium channel, Organic Chemistry, T-type calcium channel, Stereoisomerism, Calcium Channel Inhibition, Ether-A-Go-Go Potassium Channels, High-Throughput Screening Assays, Rats, Chemical evolution, Molecular Medicine, Acetamide

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cba3b145e5adacb5094a5344ec69713
    https://doi.org/10.1016/j.bmcl.2011.06.092

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  2. 2
    Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats

    المؤلفون: Emre M. Isin, David Blomberg Saitton, Eric Wellner, Rutger H. A. Folmer, Pernilla Ståhlberg, Kay Brickmann, Volker Schnecke, Öjvind Davidsson, Christoffer Bengtsson, Lars-Olof Larsson, Stefan Hallén, Pernilla Sörme, Hong Wan, Kenth Hallberg, Linda Öster, Ragnar Hovland, Lars Löfgren, Alleyn T. Plowright, Bengt Kull, Tobias Noeske, Stefan Blaho, Petra Johannesson, Tomas Drmota, Kristina Nilsson, Johan Broddefalk, Nick Oakes

    المصدر: Bioorganicmedicinal chemistry. 19(10)

    مصطلحات موضوعية: Male, Models, Molecular, Tertiary amine, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Small Molecule Libraries, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, Animals, Humans, Obesity, Enzyme Inhibitors, Molecular Biology, ADME, chemistry.chemical_classification, biology, Organic Chemistry, Fatty Acids, Acetyl-CoA carboxylase, Acetyl-CoA Carboxylase 1, Rats, Rats, Zucker, Malonyl Coenzyme A, Mice, Inbred C57BL, Enzyme, Malonyl-CoA, chemistry, Diabetes Mellitus, Type 2, Liver, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Acetyl-CoA Carboxylase

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab801bb919b253dd5e5e3a7b103724d
    https://pubmed.ncbi.nlm.nih.gov/21515056

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