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المؤلفون: Mark S. Smith, Brian Chanas, Eric Cheung, William Jeffery Edenfield, Peter J. Mutch, Adrian Hepner, Bassam Mattar, Stephen P. Anthony
المصدر: The Journal of Clinical Pharmacology. 57:1400-1408
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Bendamustine, Chemistry, Pharmaceutical, Biological Availability, Bioequivalence, Pharmacology, 03 medical and health sciences, Bendamustine hydrochloride, 0302 clinical medicine, Pharmacokinetics, Injection site reaction, medicine, Bendamustine Hydrochloride, Humans, Pharmacology (medical), Adverse effect, Aged, Aged, 80 and over, Cross-Over Studies, business.industry, Lymphoma, Non-Hodgkin, Area under the curve, Middle Aged, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Crossover study, Injection Site Reaction, 030104 developmental biology, Therapeutic Equivalency, Area Under Curve, 030220 oncology & carcinogenesis, Anesthesia, Female, business, medicine.drug
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المؤلفون: Claire E. Smith, Rossana Perciaccante, Peter R. Butchers, Alison J. Ford, Gillian Elizabeth Lunniss, Richard Conroy, Séverine Jeulin, Brian Edgar Looker, Graham Somers, Valerie S. Morrison, Amanda Emmons, Panayiotis A. Procopiou, Nicola Bevan, Victoria J. Barrett, Mark Ruston, Peter J. Mutch
المصدر: Bioorganic & Medicinal Chemistry. 19:4192-4201
مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Hydantoin, Adrenergic, Uracil, Pharmacology, Biochemistry, In vitro, Bioavailability, Guinea pig, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, Microsome, Molecular Medicine, Molecular Biology
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المؤلفون: Peter R. Butchers, Claire E. Smith, Iain M. McLay, Rosemary Sasse, Keith Biggadike, Peter J. Mutch, Panayiotis A. Procopiou, Stephen A. Richards, Richard Conroy, Diane M. Coe, Edney Dean David, Stephen Barry Guntrip, Alison J. Ford, Rita Field, Brian Edgar Looker, Nicola Bevan, Michael John Monteith, Victoria J. Barrett, Valerie S. Morrison
المصدر: Journal of Medicinal Chemistry. 52:2280-2288
مصطلحات موضوعية: Models, Molecular, Agonist, Stereochemistry, medicine.drug_class, Guinea Pigs, Administration, Oral, Biological Availability, Bronchi, CHO Cells, In Vitro Techniques, Chemical synthesis, Guinea pig, Structure-Activity Relationship, Cricetulus, Dogs, In vivo, Oral administration, Cricetinae, Microsomes, Drug Discovery, Cyclic AMP, medicine, Animals, Humans, Structure–activity relationship, Albuterol, Adrenergic beta-2 Receptor Agonists, Salmeterol Xinafoate, chemistry.chemical_classification, 2-Hydroxyphenethylamine, Sulfonamides, Chemistry, Muscle, Smooth, Stereoisomerism, In vitro, Rats, Sulfonamide, Trachea, Molecular Medicine, Muscle Contraction
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المؤلفون: Peter J. Mutch, Issy M. Ismail, Gordon J. Dear
المصدر: Journal of Pharmacy and Pharmacology. 53:403-408
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Anti-HIV Agents, Stereochemistry, Metabolite, Pharmaceutical Science, In Vitro Techniques, Antiviral Agents, Mass Spectrometry, chemistry.chemical_compound, Quinoxaline, Biotransformation, Cytochrome P-450 CYP1A2, Quinoxalines, Humans, heterocyclic compounds, Chromatography, High Pressure Liquid, Pharmacology, chemistry.chemical_classification, biology, Cytochrome P450, Nuclear magnetic resonance spectroscopy, Metabolism, Isoenzymes, Enzyme, chemistry, Microsomes, Liver, biology.protein, Isopropyl, Half-Life
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المؤلفون: Peter R. Butchers, Victoria J. Barrett, Peter J. Mutch, Andrew P. Craven, Sara C Hughes, Mark Ruston, Duncan S. Holmes, Alison J. Ford, Keith Biggadike, Brian Edgar Looker, Stephen Barry Guntrip, Anne Jones, Deborah Needham, Panayiotis A. Procopiou, Claire E. Smith
المصدر: Journal of medicinal chemistry. 57(1)
مصطلحات موضوعية: Agonist, Adrenergic receptor, medicine.drug_class, Guinea Pigs, CHO Cells, Pharmacology, Drug Administration Schedule, Sulfone, Hydroxylation, chemistry.chemical_compound, Cricetulus, Dogs, In vivo, Cricetinae, Drug Discovery, medicine, Animals, Humans, Sulfones, Adrenergic beta-2 Receptor Agonists, respiratory system, Bioavailability, Rats, Trachea, chemistry, Toxicity, Hepatocytes, Molecular Medicine, Salmeterol, medicine.drug
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المؤلفون: Brian Chanas, Stephen P. Anthony, Bassam I. Mattar, W Jeffrey Edenfield, Mark Smith, Peter J. Mutch
المصدر: Blood. 126:4857-4857
مصطلحات موضوعية: Bendamustine, medicine.medical_specialty, education.field_of_study, business.industry, Coefficient of variation, Immunology, Population, Cmax, Cell Biology, Hematology, Bioequivalence, Biochemistry, Gastroenterology, Crossover study, Surgery, Pharmacokinetics, Internal medicine, medicine, Geometric mean, business, education, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a274b9ad337552dfe19eae07b78c4e54
https://doi.org/10.1182/blood.v126.23.4857.4857 -
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المؤلفون: Brian Edgar Looker, Peter R. Butchers, Peter J. Mutch, Iain Mcfarlane Mclay, Alison J. Ford, Duncan S. Holmes, Claire E. Smith, Philip Charles Box, Inderjit Singh Mann, Helen Tracey Horsley, Richard Conroy, Valerie S. Morrison, Fern Kerr, Nicola Bevan, Amanda Emmons, Victoria J. Barrett, Panayiotis A. Procopiou, Anne-Marie Li-Kwai-Cheung, Paula Tomlin, Diane Mary Coe, Keith Biggadike
المصدر: Journal of medicinal chemistry. 53(11)
مصطلحات موضوعية: Agonist, Models, Molecular, medicine.medical_specialty, medicine.drug_class, Protein Conformation, CHO Cells, Alkylation, Pharmacology, Chlorobenzenes, Guinea pig, Structure-Activity Relationship, Cricetulus, In vivo, Internal medicine, Cricetinae, Drug Discovery, medicine, Potency, Animals, Humans, Adrenergic beta-2 Receptor Agonists, Benzyl Alcohols, Chemistry, Chinese hamster ovary cell, Adrenergic beta-Agonists, In vitro, Bioavailability, Rats, Endocrinology, Molecular Medicine, Receptors, Adrenergic, beta-2, Benzyl Alcohol
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المؤلفون: Peter J. Mutch, Graham Somers, Amanda Woodrooffe
المصدر: A Handbook of Bioanalysis and Drug Metabolism ISBN: 9780415275194
A Handbook of Bioanalysis and Drug Metabolismمصطلحات موضوعية: In Vitro Techniques, Chemistry, Pharmacology, Drug metabolism
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a99522cf4a0ad86d8640bbfefde35544
https://doi.org/10.1201/9780203642535.ch15
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