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المؤلفون: Tuğçe Oruç, Christopher M. Thomas, Peter J. Winn
مصطلحات موضوعية: chemistry.chemical_classification, Polyketide, Chemistry, Protein domain, Statistical coupling analysis, Mutagenesis (molecular biology technique), Computational biology, Site-directed mutagenesis, Peptide sequence, Function (biology), Amino acid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ed94cd518f52b96c79e7e17f9a39d973
https://doi.org/10.1101/2021.06.30.450545 -
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المؤلفون: Edwin H. Aponte Angarita, Jack Yule, Peter J. Winn, Ian R. Henderson, Rachael A. Chandler, Damon Huber, Tamar Cranford-Smith, Timothy J. Knowles, Ashley Robinson, Janet E. Lovett, Mohammed Jamshad, Karl A. Dunne, Mark Jeeves, Cailean Carter, Farhana Alam, Mashael Alanazi
المساهمون: The Royal Society, The Wellcome Trust, University of St Andrews. School of Physics and Astronomy, University of St Andrews. Biomedical Sciences Research Complex
المصدر: J Biol Chem
مصطلحات موضوعية: Iron, QH301 Biology, 010402 general chemistry, medicine.disease_cause, environment and public health, 01 natural sciences, Biochemistry, Ribosome, Copurification, Metal ion-protein interaction, Serine, 03 medical and health sciences, chemistry.chemical_compound, QH301, Protein structure, Protein Domains, Sec pathway, medicine, QD, Sodium Azide, Molecular Biology, Escherichia coli, QC, 030304 developmental biology, 0303 health sciences, Protein translocation, SecA Proteins, Escherichia coli K12, Chemistry, Escherichia coli Proteins, DAS, Cell Biology, QD Chemistry, 0104 chemical sciences, Transport protein, QC Physics, Protein Structure and Folding, Mutation, Biophysics, Sodium azide, bacteria, Azide, Protein secretion, Protein Binding
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f906daffcbecfde4e5d3464e5af1cee
https://hdl.handle.net/10023/19770 -
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المؤلفون: Iain B. Styles, Helen J. Cooper, David H. Russell, Anna L. Simmonds, Andrea F. Lopez-Clavijo, Peter J. Winn
المصدر: J Phys Chem B
مصطلحات موضوعية: Models, Molecular, Phosphopeptides, Molecular model, Ion-mobility spectrometry, Amino Acid Motifs, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Mass Spectrometry, Article, Fragmentation (mass spectrometry), 0103 physical sciences, Ion Mobility Spectrometry, Materials Chemistry, Non-covalent interactions, Amino Acid Sequence, Physical and Theoretical Chemistry, Peptide sequence, chemistry.chemical_classification, 010304 chemical physics, Electron-capture dissociation, Phosphopeptide, Chemistry, Peptide Fragments, 0104 chemical sciences, Surfaces, Coatings and Films, Crystallography, 14-3-3 Proteins
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المؤلفون: Shu-Shan Gao, Luoyi Wang, Zhongshu Song, Joanne Hothersall, Elton R. Stevens, Jack Connolly, Peter J. Winn, Russell J. Cox, Matthew P. Crump, Paul R. Race, Christopher M. Thomas, Thomas J. Simpson, Christine L. Willis
المصدر: Angewandte Chemie. 129:3988-3992
مصطلحات موضوعية: 010405 organic chemistry, General Medicine, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences
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المؤلفون: Christopher M. Thomas, Peter J. Winn, Rohit Farmer
المصدر: PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0219435 (2019)مصطلحات موضوعية: 0301 basic medicine, Acinetobacter baumannii, Fatty Acid Synthases, Amino Acid Motifs, Plasma protein binding, 01 natural sciences, Biochemistry, Database and Informatics Methods, Biochemical Simulations, Fatty Acid Synthase, Type II, Alanine, Multidisciplinary, biology, Chemistry, Physics, Fatty Acids, Lipids, Fatty acid synthase, Mupirocin, Physical Sciences, Medicine, Engineering and Technology, lipids (amino acids, peptides, and proteins), Sequence Analysis, Research Article, Protein Binding, Carbon Sequestration, Biophysical Simulations, Multiprotein complex, Environmental Engineering, Stereochemistry, Bioinformatics, Science, Biophysics, Molecular Dynamics Simulation, Research and Analysis Methods, Biosynthesis, 03 medical and health sciences, Polyketide, Bacterial Proteins, Sequence Motif Analysis, Polyketide synthase, Genetics, Acyl Carrier Protein, Escherichia coli, Point Mutation, 010405 organic chemistry, Wild type, Biology and Life Sciences, Computational Biology, Polypeptides, 0104 chemical sciences, Biosynthetic Pathways, 030104 developmental biology, Multiprotein Complexes, Mutation, biology.protein, Peptides, Polyketide Synthases
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المؤلفون: Karthik V, Rajasekar, Shuangxi, Ji, Rachel J, Coulthard, Jon P, Ride, Gillian L, Reynolds, Peter J, Winn, Michael J, Wheeler, Eva I, Hyde, Lorna J, Smith
المصدر: The Biochemical journal. 476(5)
مصطلحات موضوعية: Bacteria, Protein Domains, Arabidopsis Proteins, Arabidopsis, Humans, Protein Structure, Secondary
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::29ae24bc664ae25125b5c8b077c58ab1
https://pubmed.ncbi.nlm.nih.gov/30782970 -
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المؤلفون: Sam Butterworth, Liam Mead, Shuangxi Ji, Tuğçe Oruç, Muhammad Fayyaz ur Rehman, Christopher M. Thomas, Peter J. Winn
المصدر: Ji, S, Oruç, T, Mead, L, Rehman, M F, Thomas, C M, Butterworth, S & Winn, P J 2019, ' Deep CDpred : Inter-residue distance and contact prediction for improved prediction of protein structure ', PLoS ONE, vol. 14, no. 1, e0205214 . https://doi.org/10.1371/journal.pone.0205214
PLoS ONE, Vol 14, Iss 1, p e0205214 (2019)
PLoS ONEمصطلحات موضوعية: Protein Structure Comparison, Models, Molecular, Support Vector Machine, Protein Structure Prediction, Protein Sequencing, Biochemistry, Database and Informatics Methods, Mathematical and Statistical Techniques, Protein structure, Sequence Analysis, Protein, Prediction methods, Macromolecular Structure Analysis, Databases, Protein, Mathematics, chemistry.chemical_classification, Agricultural and Biological Sciences(all), Statistics, Physical Sciences, Medicine, Deep neural networks, Biological system, Sequence Analysis, Algorithms, Research Article, Protein Structure, Computer and Information Sciences, Distance constraints, Neural Networks, Bioinformatics, Globular protein, Science, Research and Analysis Methods, Deep Learning, Amino Acid Sequence, Statistical Methods, Amino acid residue, Molecular Biology Techniques, Sequencing Techniques, Molecular Biology, Residue (complex analysis), Biochemistry, Genetics and Molecular Biology(all), Biology and Life Sciences, Proteins, Computational Biology, Protein Structure, Tertiary, chemistry, Protein Structure Networks, Sequence Alignment, Neuroscience, Forecasting
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5705143e4b0f0a35d2f520631edc34
https://doi.org/10.1101/425785 -
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المؤلفون: Jack A, Connolly, Amber, Wilson, Malgorzata, Macioszek, Zhongshu, Song, Luoyi, Wang, Hadi H, Mohammad, Mukul, Yadav, Maura, di Martino, Claire E, Miller, Joanne, Hothersall, Anthony S, Haines, Elton R, Stephens, Matthew P, Crump, Christine L, Willis, Thomas J, Simpson, Peter J, Winn, Christopher M, Thomas
المصدر: Scientific Reports
مصطلحات موضوعية: Mupirocin, Bacterial Proteins, Mutagenesis, Polyketides, Escherichia coli, Pseudomonas fluorescens, Polyketide Synthases, Article, Anti-Bacterial Agents, Bacillus subtilis, Plasmids
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المؤلفون: Joanne Hothersall, Zhongshu Song, Jack A. Connolly, Thomas J. Simpson, Peter J. Winn, Hadi H. Mohammad, Paul R. Race, Christine L. Willis, Christopher M. Thomas
المصدر: Mohammad, H H, Connolly, J A, Song, Z, Hothersall, J, Race, P R, Willis, C L, Simpson, T J, Winn, P J & Thomas, C M 2018, ' Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans-AT Polyketide Synthase Pathway ', ChemBioChem, vol. 19, no. 8, pp. 836-841 . https://doi.org/10.1002/cbic.201800036
مصطلحات موضوعية: Stereochemistry, BrisSynBio, 010402 general chemistry, medicine.disease_cause, Hydroxylation, 01 natural sciences, Biochemistry, antibiotics, Mixed Function Oxygenases, Substrate Specificity, hydroxylation, Polyketide, chemistry.chemical_compound, In vivo, Dioxygenase, Polyketide synthase, medicine, Molecular Biology, Synthetic biology, mupirocin, Mutation, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Bristol BioDesign Institute, Substrate (chemistry), In vitro, 0104 chemical sciences, Anti-Bacterial Agents, biology.protein, Molecular Medicine, thiomarinol, Polyketide Synthases, polyketides
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d2026ceac28f9acda4ee2da1cf8ce8
http://www.scopus.com/inward/record.url?scp=85043569007&partnerID=8YFLogxK -
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المؤلفون: Rohit Farmer, Peter J. Winn, Christopher M. Thomas
المصدر: Current trends in Bioinformatics: An Insight ISBN: 9789811074813
مصطلحات موضوعية: Synthetic biology, Polyketide, biology, Metagenomics, Polyketide synthase, Protein domain, biology.protein, Macromolecular Complexes, medicine, Computational biology, Secondary metabolite, Function (biology), medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd0863d6725299e454ccdb50755457a9
https://doi.org/10.1007/978-981-10-7483-7_7
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