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1دورية أكاديميةIn vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer
المؤلفون: Loretta M S Lau, Chelsea Mayoh, Jinhan Xie, Paulette Barahona, Karen L MacKenzie, Marie Wong, Alvin Kamili, Maria Tsoli, Tim W Failes, Amit Kumar, Emily V A Mould, Andrew Gifford, Shu‐Oi Chow, Mark Pinese, Jamie I Fletcher, Greg M Arndt, Dong‐Anh Khuong‐Quang, Carol Wadham, Daniel Batey, Georgina Eden, Peter Trebilcock, Swapna Joshi, Stephanie Alfred, Anjana Gopalakrishnan, Aaminah Khan, Dylan Grebert Wade, Patrick A Strong, Elodie Manouvrier, Lisa T Morgan, Miriam Span, Jin Yi Lim, Roxanne Cadiz, Caitlin Ung, David M Thomas, Katherine M Tucker, Meera Warby, Geoffrey B McCowage, Luciano Dalla‐Pozza, Jennifer A Byrne, Federica Saletta, Andrew Fellowes, Stephen B Fox, Murray D Norris, Vanessa Tyrrell, Toby N Trahair, Richard B Lock, Mark J Cowley, Paul G Ekert, Michelle Haber, David S Ziegler, Glenn M Marshall
المصدر: EMBO Molecular Medicine, Vol 14, Iss 4, Pp n/a-n/a (2022)
مصطلحات موضوعية: drug screen, patient‐derived xenograft, pediatric cancer, precision medicine, Medicine (General), R5-920, Genetics, QH426-470
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Anahid Ehteda, Sandy Simon, Laura Franshaw, Federico M. Giorgi, Jie Liu, Swapna Joshi, Jourdin R.C. Rouaen, Chi Nam Ignatius Pang, Ruby Pandher, Chelsea Mayoh, Yujie Tang, Aaminah Khan, Caitlin Ung, Ornella Tolhurst, Anne Kankean, Elisha Hayden, Rebecca Lehmann, Sylvie Shen, Anjana Gopalakrishnan, Peter Trebilcock, Katerina Gurova, Andrei V. Gudkov, Murray D. Norris, Michelle Haber, Orazio Vittorio, Maria Tsoli, David S. Ziegler
المصدر: Cell Reports, Vol 35, Iss 2, Pp 108994- (2021)
مصطلحات موضوعية: DIPG, brainstem glioma, H3K27M, facilitates chromatin transcription complex, HDAC, EZH2, Biology (General), QH301-705.5
وصف الملف: electronic resource
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3In vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer
المؤلفون: Loretta M S Lau, Chelsea Mayoh, Jinhan Xie, Paulette Barahona, Karen L MacKenzie, Marie Wong, Alvin Kamili, Maria Tsoli, Tim W Failes, Amit Kumar, Emily V A Mould, Andrew Gifford, Shu‐Oi Chow, Mark Pinese, Jamie I Fletcher, Greg M Arndt, Dong‐Anh Khuong‐Quang, Carol Wadham, Daniel Batey, Georgina Eden, Peter Trebilcock, Swapna Joshi, Stephanie Alfred, Anjana Gopalakrishnan, Aaminah Khan, Dylan Grebert Wade, Patrick A Strong, Elodie Manouvrier, Lisa T Morgan, Miriam Span, Jin Yi Lim, Roxanne Cadiz, Caitlin Ung, David M Thomas, Katherine M Tucker, Meera Warby, Geoffrey B McCowage, Luciano Dalla‐Pozza, Jennifer A Byrne, Federica Saletta, Andrew Fellowes, Stephen B Fox, Murray D Norris, Vanessa Tyrrell, Toby N Trahair, Richard B Lock, Mark J Cowley, Paul G Ekert, Michelle Haber, David S Ziegler, Glenn M Marshall
المصدر: EMBO Molecular Medicine. 14
مصطلحات موضوعية: Disease Models, Animal, Neoplasms, Animals, Humans, Molecular Medicine, Antineoplastic Agents, Genomics, Precision Medicine, Child, Xenograft Model Antitumor Assays
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المؤلفون: Swapna Joshi, Murray D. Norris, Sandy Simon, Orazio Vittorio, Sylvie Shen, Andrei V. Gudkov, Ornella Tolhurst, Anahid Ehteda, Caitlin Ung, Jourdin R. C. Rouaen, Ruby Pandher, Aaminah Khan, Michelle Haber, Elisha Hayden, Laura Franshaw, Rebecca Lehmann, Chelsea Mayoh, Yujie Tang, Katerina Gurova, David S. Ziegler, Maria Tsoli, Federico M. Giorgi, Anjana Gopalakrishnan, Jie Liu, Chi Nam Ignatius Pang, Anne Kankean, Peter Trebilcock
المساهمون: Ehteda A., Simon S., Franshaw L., Giorgi F.M., Liu J., Joshi S., Rouaen J.R.C., Pang C.N.I., Pandher R., Mayoh C., Tang Y., Khan A., Ung C., Tolhurst O., Kankean A., Hayden E., Lehmann R., Shen S., Gopalakrishnan A., Trebilcock P., Gurova K., Gudkov A.V., Norris M.D., Haber M., Vittorio O., Tsoli M., Ziegler D.S.
المصدر: Cell Reports, Vol 35, Iss 2, Pp 108994-(2021)
مصطلحات موضوعية: 0301 basic medicine, xenograft model, Cell Cycle Proteins, Retinoblastoma Protein, Epigenesis, Genetic, Histones, Epigenome, Mice, chemistry.chemical_compound, 0302 clinical medicine, facilitates chromatin transcription complex, HDAC, Panobinostat, Brain Stem Neoplasms, Biology (General), Child, EZH2, Histone deacetylase inhibitor, High Mobility Group Proteins, Acetylation, Drug Synergism, Chromatin, pediatric cancer, DNA-Binding Proteins, DIPG, Transcriptional Elongation Factors, Neuroglia, Signal Transduction, medicine.drug_class, QH301-705.5, Primary Cell Culture, Carbazoles, Antineoplastic Agents, Methylation, General Biochemistry, Genetics and Molecular Biology, Chromatin remodeling, 03 medical and health sciences, H3K27M, Cell Line, Tumor, medicine, Animals, Humans, anticancer therapy, Histone H3 acetylation, Diffuse Intrinsic Pontine Glioma, brainstem glioma, Survival Analysis, Xenograft Model Antitumor Assays, Pediatric cancer, 030104 developmental biology, chemistry, E2F1, Cancer research, Histone deacetylase, Tumor Suppressor Protein p53, E2F1 Transcription Factor, 030217 neurology & neurosurgery, Transcription Factors
وصف الملف: ELETTRONICO
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbee79680e90f0fba780fc68415fa1d
https://hdl.handle.net/11585/831846 -
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المؤلفون: Yujie Tang, Rebecca Lehmann, Elisha Hayden, Murray D. Norris, Jie Liu, Anahid Ehteda, Aaminah Khan, Chi Nam Ignatius Pang, Michelle Haber, Sylvie Shen, Anjana Gopalakrishnan, Caitlin Ung, David S. Ziegler, Andrei V. Gudkov, Ruby Pandher, Orazio Vittorio, Chelsea Mayoh, Maria Tsoli, Anne Kankean, Federico M. Giorgi, Jourdin R. C. Rouaen, Laura Franshaw, Katerina Gurova, Peter Trebilcock, Sandy Simon
المصدر: Neuro-Oncology
مصطلحات موضوعية: Cancer Research, Chemistry, Chromatin, Cell biology, Histone H3, chemistry.chemical_compound, Oncology, Acetylation, Transcription (biology), Panobinostat, AcademicSubjects/MED00300, AcademicSubjects/MED00310, High Grade Gliomas, Neurology (clinical), Epigenetics, Histone deacetylase, Signal transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc91bb37e5f5642e3cd360b56a225c4
https://doi.org/10.1093/neuonc/noab090.075 -
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المؤلفون: Michelle Haber, Ornella Tolhurst, Murray D. Norris, Aaminah Khan, Sylvie Shen, Maria Tsoli, Jie Liu, Caitlin Ung, Orazio Vittorio, Yujie Tang, Andrei V. Gudkov, Jourdin R. C. Rouaen, Peter Trebilcock, Federico M. Giorgi, Chi Nam Ignatius Pang, Anjana Gopalakrishnan, Elisha Hayden, Swapna Joshi, Sandy Simon, David S. Ziegler, Chelsea Mayoh, Anahid Ehteda, Anne Kankean, Katerina Gurova, Ruby Pandher, Laura Franshaw
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: chemistry.chemical_compound, Histone, chemistry, biology, Panobinostat, EZH2, Cancer research, biology.protein, E2F1, Histone deacetylase, Epigenome, Epigenetics, Chromatin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23d1fb035d52de9fabce6e699861b962
https://doi.org/10.2139/ssrn.3664176 -
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المؤلفون: Peter Trebilcock
المصدر: Defining Contemporary Professionalism ISBN: 9780429347856
مصطلحات موضوعية: Multidisciplinary approach, Engineering ethics, Psychology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f7af2b6cf26e2dcf3a2d47787c6026d8
https://doi.org/10.4324/9780429347856-59 -
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المؤلفون: Noemi Fuentes Bolanos, Sumanth Nagabushan, Anjana Gopalakrishnan, S, Ziegler, David, Neevika Manoharan, Glenn M. Marshall, Greg M. Arndt, Richard B. Lock, Emily Mould, Paulette Barahona, Dong-Anh Khuong-Quang, Murray D. Norris, Toby Trahair, Chelsea Mayoh, Maely Gauthier, Mark J. Cowley, Paul G Ekert, Maria Tsoli, Michelle Haber, Katherine M. Tucker, Amit Kumar, Loretta Lau, Marie Wong, Andrew J. Gifford, Vanessa Tyrrell, Peter Trebilcock, Tim Failes, Natacha Omer
المصدر: Neuro-Oncology
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Diffuse Midline Glioma/DIPG, Precision medicine, medicine.disease, Clinical trial, Efficacy, Internal medicine, Glioma, Biopsy, DNA methylation, AcademicSubjects/MED00300, Medicine, AcademicSubjects/MED00310, Neurology (clinical), business, PI3K/AKT/mTOR pathway, Progressive disease
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54da3535968843b05bfa32e93673fca6
https://doi.org/10.1093/neuonc/noaa222.117 -
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المؤلفون: Sandy Simon, Jie Liu, Katerina Gurova, Michelle Haber, Sandra George, Ruby Pandher, Laura Franshaw, Anahid Ehteda, Orazio Vittorio, Elisha Hayden, Caitlin Ung, Murray D. Norris, Maria Tsoli, Rebecca Lehmann, Anjana Gopalakrishnan, Federico M. Giorgi, Swapna Joshi, Ornella Tolhurst, Andrei Gudkov, Aaminah Khan, Dannielle Upton, David S. Ziegler, Peter Trebilcock, Chelsea Mayoh, Chi Nam Ignatius Pang
المصدر: Neuro-Oncology
مصطلحات موضوعية: Cancer Research, Retinoblastoma, Diffuse Midline Glioma/DIPG, medicine.disease, Chromatin, chemistry.chemical_compound, Histone H3, Oncology, chemistry, Acetylation, Transcription (biology), Panobinostat, Cancer research, medicine, AcademicSubjects/MED00300, AcademicSubjects/MED00310, Neurology (clinical), Histone deacetylase, Signal transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d29680a7ddb4562e585fcc50def881d
https://doi.org/10.1093/neuonc/noaa222.076 -
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المؤلفون: Tracey A. O'Brien, Patrick Strong, Anjana Gopalakrishnan, Katherine M. Tucker, Amit Kumar, Dylan Grebert-Wade, Glenn M. Marshall, Tim Failes, Alexandra Sherstyuk, Vanessa Tyrrell, Richard B. Lock, David S. Ziegler, Caitlin Ung, Marc Cowley, Dong Anh Khuong Quang, Paulette Barahona, Chelsea Mayoh, Toby Trahair, Ornella Tolhurst, Greg M. Arndt, Maria Tsoli, Marie Wong, Michelle Haber, Andrew J. Gifford, Peter Trebilcock, Meera Warby, Loretta Lau, Murray D. Norris, Paul G Ekert, Emily Mould
المصدر: Neuro-Oncology. 21:ii118-ii118
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, business.industry, Childhood cancer, Cancer, medicine.disease, Precision medicine, Internal medicine, medicine, Neurology (clinical), Translational Therapeutics, business, Platelet-Derived Growth Factor alpha Receptor, Protein p53
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b8327ad577dcae3b9931d28c97f453
https://doi.org/10.1093/neuonc/noz036.228