المؤلفون: Horlbeck, Max A, Xu, Albert, Wang, Min, Bennett, Neal K, Park, Chong Y, Bogdanoff, Derek, Adamson, Britt, Chow, Eric D, Kampmann, Martin, Peterson, Tim R, Nakamura, Ken, Fischbach, Michael A, Weissman, Jonathan S, Gilbert, Luke A

المصدر: Cell. 174(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Genetics, Biological Sciences, Biotechnology, Human Genome, Aetiology, 2.1 Biological and endogenous factors, Generic health relevance, Biomarkers, Cholesterol, Clustered Regularly Interspaced Short Palindromic Repeats, Epistasis, Genetic, Gene Regulatory Networks, High-Throughput Nucleotide Sequencing, Humans, Jurkat Cells, K562 Cells, Protein Interaction Mapping, CRISPR, CRISPRi, epistasis, functional genomics, genetic interactions, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0465k3fx

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المؤلفون: Li J; Department of Medicine, Department of Genetics, Institute for Public Health, Washington University School of Medicine, BJC Institute of Health, 425 S. Euclid Ave., St. Louis, MO 63110, USA.; BIOIO, 4340 Duncan Ave. Suite 236, St. Louis, MO 63110, USA.; Healthspan Technologies, 4340 Duncan Ave. Suite 265, St. Louis, MO 63110, USA., Kumar S; Department of Medicine, Department of Genetics, Institute for Public Health, Washington University School of Medicine, BJC Institute of Health, 425 S. Euclid Ave., St. Louis, MO 63110, USA., Miachin K; Department of Medicine, Department of Genetics, Institute for Public Health, Washington University School of Medicine, BJC Institute of Health, 425 S. Euclid Ave., St. Louis, MO 63110, USA.; BIOIO, 4340 Duncan Ave. Suite 236, St. Louis, MO 63110, USA., Bean NL; Department of Medicine, Department of Genetics, Institute for Public Health, Washington University School of Medicine, BJC Institute of Health, 425 S. Euclid Ave., St. Louis, MO 63110, USA.; BIOIO, 4340 Duncan Ave. Suite 236, St. Louis, MO 63110, USA., Halawi O; BIOIO, 4340 Duncan Ave. Suite 236, St. Louis, MO 63110, USA., Lee S; BIOIO, 4340 Duncan Ave. Suite 236, St. Louis, MO 63110, USA., Park J; Department of Medicine, Department of Genetics, Institute for Public Health, Washington University School of Medicine, BJC Institute of Health, 425 S. Euclid Ave., St. Louis, MO 63110, USA., Pierre TH; Department of Medicine, Department of Genetics, Institute for Public Health, Washington University School of Medicine, BJC Institute of Health, 425 S. Euclid Ave., St. Louis, MO 63110, USA., Hor JH; Institute of Molecular and Cell Biology (Cell Biology and Therapies Division), A*STAR Research Entities. 61 Biopolis Drive, 138673, Singapore., Ng SY; Institute of Molecular and Cell Biology (Cell Biology and Therapies Division), A*STAR Research Entities. 61 Biopolis Drive, 138673, Singapore., Wallace KJ; LabDAO, c/o MJP PARTNERS, Bahnhofstrasse 20, 6300 Zug, Switzerland., Rindtorff N; LabDAO, c/o MJP PARTNERS, Bahnhofstrasse 20, 6300 Zug, Switzerland., Miller TM; Department of Neurology, Washington University School of Medicine, BJC Institute of Health, 425 S. Euclid Ave., St. Louis, MO 63110, USA., Niehoff ML; Department of Internal Medicine, Division of Geriatric Medicine; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, 1402 S. Grand Blvd, St. Louis, MO 63110, USA. Research and Development, VA Medical Center-St. Louis, 915 N. Grand Blvd. St. Louis, MO 63106, USA., Farr SA; Department of Internal Medicine, Division of Geriatric Medicine; Department of Pharmacology and Physiology, Saint Louis University School of Medicine, 1402 S. Grand Blvd, St. Louis, MO 63110, USA. Research and Development, VA Medical Center-St. Louis, 915 N. Grand Blvd. St. Louis, MO 63106, USA., Kletzien RF; Metabolic Solutions Development Company. 161 E Michigan Ave., 4th Floor Kalamazoo, MI 49007, USA., Colca J; Metabolic Solutions Development Company. 161 E Michigan Ave., 4th Floor Kalamazoo, MI 49007, USA., Tanis SP; Metabolic Solutions Development Company. 161 E Michigan Ave., 4th Floor Kalamazoo, MI 49007, USA., Chen Y; Department of Medicine, Division of Geriatrics & Nutritional Sciences, Washington University School of Medicine, MSC 8031-0014-01, 660 S. Euclid Ave., St. Louis, MO 63110, USA., Griffett K; Department of Anatomy, Physiology and Pharmacology, Auburn University, College of Veterinary Medicine, 1130 Wire Road, Auburn, AL 36849, USA., McCommis KS; Department of Biochemistry & Molecular Biology, Saint Louis University School of Medicine, 1100 S. Grand Blvd., St. Louis, MO 63104, USA., Finck BN; Department of Medicine, Division of Geriatrics & Nutritional Sciences, Washington University School of Medicine, MSC 8031-0014-01, 660 S. Euclid Ave., St. Louis, MO 63110, USA., Peterson TR; Department of Medicine, Department of Genetics, Institute for Public Health, Washington University School of Medicine, BJC Institute of Health, 425 S. Euclid Ave., St. Louis, MO 63110, USA.; BIOIO, 4340 Duncan Ave. Suite 236, St. Louis, MO 63110, USA.; Healthspan Technologies, 4340 Duncan Ave. Suite 265, St. Louis, MO 63110, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jan 19. Date of Electronic Publication: 2023 Jan 19.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Peterson TR; The Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA., Sabatini DM

المصدر: Molecular cell [Mol Cell] 2005 Dec 09; Vol. 20 (5), pp. 655-7.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Print ISSN: 1097-2765 (Print) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Eukaryotic Initiation Factor-3/*metabolism , Protein Kinases/*metabolism , Ribosomal Protein S6 Kinases, 70-kDa/*metabolism, Animals ; Eukaryotic Initiation Factor-3/chemistry ; Models, Biological ; Protein Kinases/chemistry ; Ribosomal Protein S6 Kinases, 70-kDa/chemistry ; TOR Serine-Threonine Kinases