المؤلفون: Prachi Anand, Petr Filipenko, Jeannette Huaman, Michael Lyudmer, Marouf Hossain, Carolina Santamaria, Kelly Huang, Olorunseun O. Ogunwobi, Mandë Holford

المصدر: Marine Drugs, Vol 17, Iss 10, p 587 (2019)

مصطلحات موضوعية: venom peptide, liver cancer, terebrid snail, trp channel, cox-2, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1660-3397/17/10/587; https://doaj.org/toc/1660-3397

URL الوصول: https://doaj.org/article/2b428e0cf1d54c06a0e4a0a927764873

المؤلفون: Jeannette Huaman, Michael Lyudmer, Carolina Santamaria, Prachi Anand, Marouf Hossain, Kelly Huang, Olorunseun O. Ogunwobi, Petr Filipenko, Mandë Holford

المصدر: Marine Drugs, Vol 17, Iss 10, p 587 (2019)
Marine Drugs
Volume 17
Issue 10

مصطلحات موضوعية: trp channel, Carcinoma, Hepatocellular, medicine.medical_treatment, Down-Regulation, Mollusk Venoms, Pharmaceutical Science, Apoptosis, Peptide, Article, Cell Line, Targeted therapy, liver cancer, Mice, 03 medical and health sciences, Transient receptor potential channel, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, venom peptide, medicine, Animals, Humans, terebrid snail, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), cox-2, lcsh:QH301-705.5, Ion channel, 030304 developmental biology, chemistry.chemical_classification, Mice, Inbred BALB C, 0303 health sciences, Liver Neoplasms, Cancer, Hep G2 Cells, medicine.disease, 3. Good health, Gene Expression Regulation, Neoplastic, chemistry, Mechanism of action, lcsh:Biology (General), Cyclooxygenase 2, 030220 oncology & carcinogenesis, Cancer research, Female, medicine.symptom, Peptides, Liver cancer

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86358f2afbed0b40b09901a08509ef3
https://www.mdpi.com/1660-3397/17/10/587

المؤلفون: Olorunseun O. Ogunwobi, Carolina Santamaria, Michael Lyudmer, Prachi Anand, Jeannette Huaman, Kelly Huang, Mandë Holford, Marouf Hossain, Petr Filipenko

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Chemistry, medicine.medical_treatment, Cell, Cancer, Peptide, Venom, medicine.disease, 3. Good health, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Mechanism of action, Apoptosis, 030220 oncology & carcinogenesis, Cancer research, medicine, medicine.symptom, Liver cancer, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847742029f9a9fc4a8ab9d002cf4c1ab
https://doi.org/10.1101/518340

المؤلفون: Christina Sizun, Julia Chamot-Rooke, Françoise Bonneté, Sébastien Brier, Claudine Mayer, Bertrand Raynal, Françoise Norel, Patrick England, Paola Cavaliere, Fabienne Levi-Acobas, Petr Filipenko, Jacques Bellalou

المساهمون: Systèmes macromoléculaires et Signalisation, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Spectrométrie de Masse structurale et protéomique, Spectrométrie de Masse pour la Biologie – Mass Spectrometry for Biology (UTechS MSBio), Institut Pasteur [Paris]-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Department of Computer Science [New York], New York University [New York] (NYU), NYU System (NYU)-NYU System (NYU), Institut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Biophysique Moléculaire (Plate-forme), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Production de Protéines Recombinantes (Plate-Forme) (PRPF), Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Biochimie des Interactions Macromoléculaires / Biochemistry of Macromolecular Interactions, This work was supported by the French National Research Agency [grant ANR-11-BSV3-009] and by grants from the Institut Pasteur and the Centre National de la Recherche Scientifique. The MS work was supported by the Investissements d’Avenir through the CACSICE project [grant ANR-11-EQPX-008]. Access to high-field NMR spectrometers financially supported by IR-RMN-THC FR3050 CNRS is gratefully acknowledged., ANR-11-BSV3-0009,SIGMADAPT,Rôle de SigmaS dans la compétitivité et l'adaptation des bactéries à l'environnement(2011), ANR-11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes(2011), Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Biochimie des Interactions Macromoléculaires, Centre National de la Recherche Scientifique (CNRS)-Centre de Ressources et de Recherche Technologique - Center for Technological Resources and Research (C2RT), Institut Pasteur [Paris]-Institut Pasteur [Paris], ANR-11-EQPX-0008/11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes(2011), Centre de Ressources et de Recherche Technologique - Center for Technological Resources and Research (C2RT), Institut Pasteur [Paris]-Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université Paris Diderot - Paris 7 (UPD7)-Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique ( CNRS ), New York University [New York], Institut de Chimie des Substances Naturelles ( ICSN ), Centre National de la Recherche Scientifique ( CNRS ), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] ( IBMM ), Ecole Nationale Supérieure de Chimie de Montpellier ( ENSCM ) -Université de Montpellier ( UM ) -Centre National de la Recherche Scientifique ( CNRS ), Production de Protéines Recombinantes (Plate-Forme) ( PRPF ), Microbiologie structurale, Spectrométrie de Masse pour la Biologie – Mass Spectrometry for Biology ( UTechS MSBio ), ANR-11-BSV3-0009,SIGMADAPT,Rôle de SigmaS dans la compétitivité et l'adaptation des bactéries à l'environnement ( 2011 ), ANR-11-EQPX-0008/11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes ( 2011 ), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Avignon Université (AU), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Biochemical Journal
Biochemical Journal, Portland Press, 2018, 475 (1), pp.341-354. ⟨10.1042/BCJ20170768⟩
Biochemical Journal, Portland Press, 2018, 475 (1), pp.341-354. 〈10.1042/BCJ20170768〉
Biochemical Journal, 2018, 475 (1), pp.341-354. ⟨10.1042/BCJ20170768⟩

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], 030106 microbiology, Biochemistry, 03 medical and health sciences, Molecular dynamics, chemistry.chemical_compound, Protein structure, RpoS, Sigma factor, protein conformation, Salmonella, RNA polymerase, Molecule, protein structure, Molecular Biology, [ SDV ] Life Sciences [q-bio], biology, Cell Biology, Crystallography, 030104 developmental biology, chemistry, Chaperone (protein), biology.protein, Hydrogen–deuterium exchange, sigma factor, rpoS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af9a5bed177c502c9d4e170be5e4403
https://hal-pasteur.archives-ouvertes.fr/pasteur-01685123/document

المؤلفون: Paola, Cavaliere, Sébastien, Brier, Petr, Filipenko, Christina, Sizun, Bertrand, Raynal, Françoise, Bonneté, Fabienne, Levi-Acobas, Jacques, Bellalou, Patrick, England, Julia, Chamot-Rooke, Claudine, Mayer, Françoise, Norel

المصدر: The Biochemical journal. 475(1)

مصطلحات موضوعية: Protein Conformation, alpha-Helical, Salmonella typhimurium, Protein Folding, Binding Sites, Recombinant Fusion Proteins, Deuterium Exchange Measurement, Sigma Factor, Gene Expression Regulation, Bacterial, Molecular Dynamics Simulation, Crystallography, X-Ray, Protein Structure, Tertiary, Kinetics, Bacterial Proteins, Escherichia coli, Solvents, Thermodynamics, Protein Conformation, beta-Strand, Protein Interaction Domains and Motifs, Holoenzymes, Promoter Regions, Genetic, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6142c83726b7adf8b86c43b1524b7997
https://pubmed.ncbi.nlm.nih.gov/29229758

المؤلفون: Annette Nicke, Anna Heizmann, Richard W. Tsien, Alexander Kuryatov, Bernardo Rudy, Petr Filipenko, Henry Zebroski, Jon Lindstrom, Susan R. Powell, Sergey Lyskov, Richard Bonneau, Adel K. Hussein, Sébastien F. Poget, Abba E. Leffler, Juliette Gorson, Mandë Holford

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 114(38)

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Peptide, Nicotinic Antagonists, Receptors, Nicotinic, complex mixtures, 03 medical and health sciences, DOCK, mental disorders, Aplysia, Animals, Humans, Homology modeling, Conotoxin, Ion channel, chemistry.chemical_classification, Virtual screening, Multidisciplinary, Chemistry, musculoskeletal, neural, and ocular physiology, Molecular Docking Simulation, Nicotinic acetylcholine receptor, 030104 developmental biology, nervous system, PNAS Plus, Docking (molecular), sense organs, Conotoxins, Algorithms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846f5c284a1b394e6c75d91d944d166e
https://pubmed.ncbi.nlm.nih.gov/28874590