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المؤلفون: Fanny Caputo, C.A.W. David, R.J. Vandebriel, Matteo Santin, B. Halamoda-Kenzaoui, A. Howarth, Sven Even F. Borgos, S. Bremer-Hoffmann, Marco Siccardi, Neill J. Liptrott
المصدر: Journal of Controlled Release
JOURNAL OF CONTROLLED RELEASEمصطلحات موضوعية: Test strategy, Computer science, media_common.quotation_subject, Regulatory needs, CEN, European Committee for Standardisation, ADME, Absorption, Distribution, Metabolism, Excretion, ICH, International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use, Pharmaceutical Science, Nanotechnology, Information needs, 02 engineering and technology, Review Article, EUNCL, European Nanomedicine Characterisation Laboratory, Gap analysis, PCC, Physicochemical characterisation, PK, Pharmacokinetic, 03 medical and health sciences, CARPA, Complement Activation related Pseudo-allergy, Quality (business), Product (category theory), API, Active Pharmaceutical Ingredient, Adaptation (computer science), NPs, Nanoparticles, 030304 developmental biology, media_common, 0303 health sciences, Ph. Eur., European Pharmacopoeia, PBPK, Physiologically based pharmacokinetic, Nanomedicine, nanotechnology-based products, regulatory needs, methodological gaps, method standardisation, method development, physicochemical characterisation, immunotoxicity assessment, Method development, Health technology, Reference Standards, 021001 nanoscience & nanotechnology, FDA, Food and Drug Administration, NCI-NCL, Nanotechnology Characterisation Laboratory, 3. Good health, Method standardisation, Identification (information), Nanotechnology-based products, Nanomedicine, Physicochemical characterisation, EMA, European Medicines Agency, ISO, International Standardisation Organisation, Immunotoxicity assessment, 0210 nano-technology, Methodological gaps
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document
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المؤلفون: Maria Assunta Acquavia, Raffaella Pascale, Luca Foti, Laura Scrano, Antonia Nicolò, Vincenzo Brancaleone, Giuseppe Martelli, Tommaso R. I. Cataldi, Giuliana Bianco
المصدر: Talanta
مصطلحات موضوعية: HILIC, hydrophilic interaction liquid chromatography, PIs, protease inhibitors, RSD, relative standard deviation, Review, CE, capillary electrophoresis, MSI, MALDI-MS Imaging, 02 engineering and technology, Chemical Fractionation, Biological matrices, Pharmacology, CSF, cerebrospinal fluid, 01 natural sciences, Analytical Chemistry, Drug detection, MRM, Muliple Reaction Monitoring, OSP, oseltamivir phosphate, Tandem Mass Spectrometry, TDM, therapeutic drug monitoring, Ph. Eur, European Pharmacopoeia, Chromatography, High Pressure Liquid, ESI, electrospray ionization, LC, liquid chromatography, Chemistry, FL, fluorescence, Antivirals, 021001 nanoscience & nanotechnology, RdRpIs, RNA polymerase inhibitors, LLE, liquid-liquid extraction, Err, absolute value of the relative error, 0210 nano-technology, Q-MSI, quantitative MALDI-MS Imaging, RE, relative error, SDS, sodium dodecyl sulfate, Coronavirus disease 2019 (COVID-19), MALDI, matrix-assisted laser desorption/ionization, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), PSA, primary-secondary amine, Liquid chromatography, HLB, hydrophilic-lipophilic balance, LLOQ, lower limit of quantification, Q, QuEChERS, TCA, trichloroacetic acid, Quechers, Antiviral Agents, CHCA, α-cyano-4-hydroxycinnamic acid, BeWos, human placental choriocarcinoma trophobplast cells, Capillary electrophoresis, Pharmacokinetics, Analytical methods, UAE, ultrasound assisted extraction, PMA, phosphomolybdic acid, Biological fluids, Animals, Humans, ADME, adsorption, distribution, metabolism, and elimination, ICH, International Conference on Harmonization, Pandemics, SRM, Selected Reaction Monitoring, PBA, phenylboronic acid, LOQ, limit of quantification, PBMCs, peripheral blood mononuclear cells, UHPLC, ultra-high performance liquid chromatography, LOD, limit of detection, Mass spectrometry, SARS-CoV-2, SPE, solid-phase extraction, 010401 analytical chemistry, d-SPE, dispersive-sold-phase extraction, COVID-19, CV, coefficient of variation, MTBE, methyltertbutyl ether, ACN, acetonitrile, FDA, Food and Drug Administration, COVID-19 Drug Treatment, 0104 chemical sciences, MCX, mixed-mode cationic exchange, QC, quality control, Clinical trial, NRTIs, nucleoside reverse transcriptase inhibitors, PP, protein precipitation, MS, mass spectrometry, MLC, micellar liquid chromatography, CRMs, certified reference materials, DEV, deviation from nominal concentration value, EMA, European Medicines Agency, AD, absolute deviation, DHB, 2,5-dihydroxybenzoic acid
