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المؤلفون: Giulia Usai, Alessandro Cordara, Angela Re, Maria Francesca Polli, Giuseppe Mannino, Cinzia Margherita Bertea, Debora Fino, Candido Fabrizio Pirri, Barbara Menin
المصدر: Frontiers in bioengineering and biotechnology. 10
مصطلحات موضوعية: Phe, Histology, shikimate pathway, gene encoding for Shikimate Kinase, phenylalanine, Biomedical Engineering, aroK, Bioengineering, cyanobacteria, 3-deoxy-D-arabino-heptulosonate 7-phosphate, 2-PE, metabolite doping, aromatic amino acid, IPTG, AAA, feedback-inhibition resistant, photosynthesis, 2-PE, 2-phenylethanol, AAA, aromatic amino acid, aroK, gene encoding for Shikimate Kinase, DAHP, 3-deoxy-D-arabino-heptulosonate 7-phosphate, fbr, feedback-inhibition resistant, IPTG, Isopropyl β-D-1-thiogalactopyranoside, Phe, phenylalanine, SK, shikimate kinase, SKP, shikimate pathway, SK, 2-phenylethanol, aromatics, shikimate kinase, fbr, SKP, Isopropyl β-D-1-thiogalactopyranoside, DAHP, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4886f89703a0ed4a5aff17333c8ff377
https://pubmed.ncbi.nlm.nih.gov/36204466 -
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المؤلفون: Bojana Rakic, Hilary Vallance, Joshua A. Dubland, Graham Sinclair
المصدر: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss, Pp 1-10 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Labمصطلحات موضوعية: Newborn screening, MS/MS, tandem mass spectrometry, 2-Methylcitric acid, Homocysteine, Clinical Biochemistry, rpm, revolutions per minute, Methylmalonic acid, Tandem mass spectrometry, MMA, methylmalonic acid, NBS, newborn screening, chemistry.chemical_compound, DMAP, 4-(dimethylamino)pyridine, Met, methionine, Liquid chromatography–mass spectrometry, HCl, hydrochloric acid, health care economics and organizations, DBS, dried blood spot, Spectroscopy, FA, formic acid, ESI, electrospray ionization, Second-tier, LC, liquid chromatography, food and beverages, Regular Article, Dried blood spot, Medical Laboratory Technology, Specimen collection, S/N, signal-to-noise, GC, gas chromatography, Phe, phenylalanine, DAABD-AE, 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole, LLOQ, lower limit of quantitation, Analyte, HCY, homocysteine, education, MCA, 2-methylcitric acid, Cbl, cobalamin, Microbiology, LLOD, lower limit of detection, GPCho’s, glycerophosphocholines, health services administration, EDC, N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride, Medical technology, C2, acetylcarnitine, R855-855.5, Derivatization, CBS, cystathionine β-synthase, MPs, mobile phases, Chromatography, Mass spectrometry, C3, propionylcarnitine, PPV, positive predictive value, QC, quality control, MS, mass spectrometry, chemistry, DTT, dithiothreitol, MRM, multiple reaction monitoring
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50beebd48c7a916d499a13356b9284c0
https://doi.org/10.1016/j.jmsacl.2021.03.001 -
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المؤلفون: Hulya Gokmen-Ozel, Esther van Dam, Amaya Belanger-Quintana, Fran Rohr, Alexandra Jung, Júlio César Rocha, Laurie Bernstein, Anita MacDonald, Heather Bausell, Margret Heddrich-Ellerbrok
المساهمون: NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
المصدر: Molecular Genetics and Metabolism Reports, Vol 28, Iss, Pp 100771-(2021)
Molecular genetics and metabolism reports, 28:100771. ELSEVIER SCIENCE BV
Molecular Genetics and Metabolism Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAPمصطلحات موضوعية: medicine.medical_specialty, Medicine (General), QH301-705.5, BMI, body mass index, Phenylalanine, PKU, phenylketonuria, LBP, low blood phenylalanine, Pegvaliase, PHE - Phenylalanine, DXA, dual-energy x-ray absorptiometry, Dietitian, CHLC MTB, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, R5-920, Educational support, Genetics, Medicine, Phenylketonuria, Phenylketonuria (PKU), Road map, Biology (General), Molecular Biology, Nutrition, 0303 health sciences, PAH, phenylalanine hydroxylase, business.industry, 030305 genetics & heredity, DRI, dietary reference intake, Treatment team, medicine.disease, FDA, Food and Drug Administration, QoL, quality of life, SAPROPTERIN DIHYDROCHLORIDE, Nutritionist, Family medicine, PKU, PAL, PEGylated recombinant phenylalanine ammonia lyase, EMA, European Medicines Agency, Phe, phenylalanine, business, 030217 neurology & neurosurgery, BMI - Body mass index, Research Paper
وصف الملف: application/pdf
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المؤلفون: Prem Rajak, Sumedha Roy, Achintya Kumar Pal, Manas Paramanik, Moumita Dutta, Sayanti Podder, Saurabh Sarkar, Abhratanu Ganguly, Moutushi Mandi, Anik Dutta, Kanchana Das, Siddhartha Ghanty, Salma Khatun
المصدر: Current Research in Toxicology, Vol 2, Iss, Pp 411-423 (2021)
Current Research in Toxicology
CURRENT RESEARCH IN TOXICOLOGYمصطلحات موضوعية: Carbohydrate recognition domain, THR, Threonine, Health, Toxicology and Mutagenesis, Surfactant protein, INHIBITION, Toxicology, VAL, Valine, Applied Microbiology and Biotechnology, Article, ARG, Arginine, HIS, Histidine, CYS, Cysteine, Rotenone, RA1190-1270, GLU, Glutamic acid, Medicine and Health Sciences, GLY, Glycine, EXPOSURE, PRO, Proline, TYR, Tyrosine, PALMITOYLATION, SER, Serine, ComputingMethodologies_COMPUTERGRAPHICS, SP-A, SP-B, LEU, Leucine, GLYCOPROTEIN, Biology and Life Sciences, ALA, Alanine, DYSFUNCTION, APOPTOSIS, ENHANCES PHAGOCYTOSIS, ASP, Aspartic acid, PHE, Phenylalanine, ILE, Isoleucine, LYS, Lysine, TRP, Tryptophan, Molecular docking, Toxicology. Poisons, GLN, Glutamine, Lungs, CARBOHYDRATE-RECOGNITION DOMAIN, MET, Methionine, ASN, Asparagine
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f2cd79baf46b999beeed39c977274d
http://www.sciencedirect.com/science/article/pii/S2666027X21000414 -
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المؤلفون: Elaina Jurecki, Nicola Longo, H. Serap Sivri, Deborah A. Bilder, Janet A. Thomas, Christoph Baerwald, Gisela Wilcox, Kathleen A. Delaney, Cary O. Harding, Anne Skalicky, Aaron B. Ilan, Barbara K. Burton, David T. Madden
المصدر: Molecular Genetics and Metabolism Reports, Vol 29, Iss, Pp 100810-(2021)
Molecular Genetics and Metabolism Reportsمصطلحات موضوعية: IRB, Institutional Review Board, OGI, Observer Global Impression, Medicine (General), Phe, Phenylalanine, PAH, Phenylalanine Hydroxylase, QH301-705.5, HRQoL, Health-Related Quality of Life, PKU, Phenylketonuria, ObsROs, Observer-Reported Outcomes, Clinical outcome assessments, Outcome (game theory), Endocrinology, R5-920, Genetics, Content validity, Phenylketonuria, Adults, Biology (General), Molecular Biology, ADHD RS-IV, Attention Deficit Hyperactivity Disorders Rating Scale-IV, QoL, Quality of Life, ADHD, Attention Deficit Hyperactivity Disorder, PROs, Patient-Reported Outcomes, Observer-reported outcomes, Patient-reported outcomes, PGI, Patient Global Impression, COAs, Clinical Outcome Assessments, Cognition, CAARS-O:Long, Conners' Adult ADHD Rating Scales-Observer Report Long Version, ClinROs, Clinician-Reported Outcomes, PROMIS, Patient Reported Outcome Measurement Information System, FDA, Food and Drug Administration, Interaction time, Clinical trial, CGI, Clinician Global Impression, Neuro-QoL, Quality of Life in Neurological Disorders, PKU, Cohort, Non interventional, Observational study, Psychology, Clinician-reported outcomes, COIs, Concepts Of Interests, PKU-QOL, PKU Quality of Life, Clinical psychology, Research Paper
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المؤلفون: Wei Gao, Li Yanpeng, Yan Yin, Chunsheng Liu, Xianan Zhang, Dan Jiang
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 4, Pp 711-721 (2020)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: C4H, cinnamate 4-hydroxylase, Original article, Saccharomyces cerevisiae, Isoliquiritigenin, UGT, UDP-glucosyltransferase, Transcriptome, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Biosynthesis, Iso-LN, isoliquiritin, Glycyrrhiza uralensis, General Pharmacology, Toxicology and Pharmaceutics, LN, liquiritin, Liquiritin, CHI, chalcone isomerase, 030304 developmental biology, MeJA, methyl jasmonate, 0303 health sciences, biology, lcsh:RM1-950, LG, liquiritigenin, Liquiritigenin, biology.organism_classification, 4CL, 4-coumarate CoA ligase, CiA, cinnamic acid, PAL, phenylalanine ammonia-lyase, Heterologous synthesis, F7GT, flavone 7-O-glucosyltransferase, lcsh:Therapeutics. Pharmacology, Flavonoid biosynthesis, chemistry, Biochemistry, Isoliquiritin, CHR, chalcone reductase, CHS, chalcone synthase, Iso-LG, isoliquiritigenin, 030220 oncology & carcinogenesis, p-CA, p-coumaric acid, Phe, phenylalanine
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المؤلفون: Klaus Schughart, Diana Cabrera, Heike Kollmus, Carolin Pilzner, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez
المصدر: The Journal of biological chemistry
United States
The Journal of Biological Chemistryمصطلحات موضوعية: MCFA, medium-chain fatty acid, medicine.medical_treatment, Type 2 diabetes, ACC, acetyl-CoA carboxylase, medicine.disease_cause, Biochemistry, Mice, DC, dendritic cell, nPY, N1-methyl-n-pyridone-5-carboxamide, PP2A, protein phosphatase 2A, Influenza A virus, ACar, acylcarnitine, Beta oxidation, LPI, lysophosphatidylinositol, ACoA, acyl-CoA, diabetes, TMAO, trimethylamine N-oxide, Peroxisome, metabolomics, dpi, days postinfection, Gln, glutamine, Val, valine, LPC, (lyso)phosphatidylcholine, Phe, phenylalanine, Oxidation-Reduction, PAMP, pathogen-associated molecular pattern, Research Article, TLR, Toll-like receptor, LPE, lysophosphatidylethanolamine, TAG, triacylglycerol, mouse model, TCA, tricarboxylic acid, Biology, VLCFA, very long–chain fatty acid, beta-oxidation, Diabetes Mellitus, Experimental, 5HIU, 5-hydroxyisourate, NAM, nicotinamide, Orthomyxoviridae Infections, hrLCMS, high-resolution liquid chromatography–coupled mass spectrometry, Diabetes mellitus, Carnitine, IAV, influenza A virus, medicine, C5, complement component 5, MCar, malonylcarnitine, Animals, influenza A virus, ABCD, ATP-binding cassette D, Molecular Biology, LME, linear mixed-effect, Innate immune system, Ahr, aryl-hydrocarbon receptor, Insulin, Ile/Leu, isoleucine/leucine, FA, fatty acid, Cell Biology, Metabolism, MS, ACN, acetonitrile, medicine.disease, MNA, N1-methylnicotinamide, CPT, carnitine palmitoyltransferase, Diabetes Mellitus, Type 2, Immunology, LCFA, long-chain fatty acid, MCoA, malonyl-coenzyme A, Amino Acids, Branched-Chain, AcCoA, acetyl coenzyme A
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35df79d0e1826add7a81f0ba6216551f
https://hdl.handle.net/10033/623093 -
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المؤلفون: Yin Huang, Yingtong Lv, Jiaqing Chen, Wei Li, Zunjian Zhang, Fengguo Xu, Yiqiao Gao, Xu Wang
المصدر: Acta Pharmaceutica Sinica B, Vol 9, Iss 1, Pp 157-166 (2019)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: Oncology, Smt, sensitive for myelosuppression toxicity, Metabolite, C, control group, RSD, relative standard deviation, NSgt, non-sensitive for gastrointestinal toxicity, pFDR, false-discovery-rate-adjusted P value, Logistic regression, CPT-11, irinotecan, OPLS-DA, orthogonal partial least-squares-discriminant analysis, chemistry.chemical_compound, VIP, variable importance in the projection, 0302 clinical medicine, GCA, glycocholic acid, Medicine, DBIL, direct bilirubin, Complicating toxicity, General Pharmacology, Toxicology and Pharmaceutics, CA, cholic acid, 0303 health sciences, AUC-ROC, area under receiver operating characteristic, Gastrointestinal toxicity, BHB, β-hydroxybutyric acid, UFLC, ultrafast liquid chromatography, MSTFA, N-methyl-N-trifluoroacetamide, Diarrhea, S, sensitive group, 030220 oncology & carcinogenesis, T, CPT-11 treated group, Toxicity, medicine.symptom, Phe, phenylalanine, Lys, lysine, Sgt, sensitive for gastrointestinal toxicity, medicine.drug, Original article, medicine.medical_specialty, Trp, tryptophan, FDR, false discovery rate, IBIL, indirect bilirubin, Irinotecan, 03 medical and health sciences, Metabolomics, Internal medicine, NS, non-sensitive group, Adverse effect, 030304 developmental biology, PCA, principal component analysis, business.industry, lcsh:RM1-950, IT-TOF/MS, ion trap/time-offlight hybrid mass spectrometry, NSmt, non-sensitive for myelosuppression toxicity, Precision medicine, QC, quality control, lcsh:Therapeutics. Pharmacology, DCA, deoxycholic acid, chemistry, Individual differences, PLS-DA, partial least-squares-discriminant analysis, Prediction, business, Biomarkers
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المؤلفون: Dong Seop Kang, Sang Jun Park, Joo Young Lee, Kang Moo Huh, Han Chang Kang, Yeon Su Choi, Min Suk Shim, Gantumur Battogtokh, Hye Suk Lee, Yong-Yeon Cho
المصدر: Acta Pharmaceutica Sinica B, Vol 8, Iss 6, Pp 862-880 (2018)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: 0301 basic medicine, AD, Alzheimer׳s disease, C-dots, carbon dots, MLS, mitochondria localization sequences, OXPHOS, oxidative phosphorylation, MPO, myeloperoxidase, TPP, triphenylphosphonium, 4-AT, 4-amino-TEMPO, mitoTEMPO, (2-(2,2,6,6-tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium), Review, GPX, glutathione peroxidase, Mitochondrion, mtPt, mitochondria-targeting (Fx,r)3-platinum(II), Antioxidants, LA, lipoic acid, VDAC/ANT, voltage-dependent anion channel/adenine nucleotide translocase, chemistry.chemical_compound, DQA, dequalinium, Direct conjugation, 0302 clinical medicine, MPP, mitochondria-penetrating peptides, SS peptide, Szeto-Schiller peptides, Dmt, dimethyltyrosine, Aβ, beta amyloid, AIE, aggregation-induced emission, 5-FU, 5-Fluorouracil, NitDOX, nitrooxy-DOX, mtCbl, (Fx,r)3-chlorambucil, General Pharmacology, Toxicology and Pharmaceutics, Cytotoxicity, Inner mitochondrial membrane, PD, Parkinson׳s disease, media_common, IMS, intermembrane space, BODIPY, boron-dipyrromethene, Chemistry, MET, mesenchymal-epithelial transition, DDS, drug delivery system, F16, (E)-4-(1H-indol-3-ylvinyl)-N-methylpyridinium iodide, VES, vitamin E succinate, MitoLA, TPP-lipoic acid, Nit, nitrooxy, LAH2, dihydrolipoic acid, Biochemistry, COX, cytochrome c oxidase, GS, gramicidin S, PDT, photodynamic therapy, 030220 oncology & carcinogenesis, DIPPMPO, 5-(diisopropoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide, OMM, outer mitochondrial membrane, Phe, phenylalanine, IMM, inner mitochondrial membrane, IOA, imidazole-substituted oleic acid, Lys, lysine, Drug, CoA, coenzyme A, ATP, adenosine triphosphate, MitoE, TPP-vitamin E, media_common.quotation_subject, TPEY-TEMPO, [2-(1-oxyl-2,2,6,6-tetramethylpiperidin-4-ylimino)-ethyl]-triphenyl-phosphonium, PS, photosensitizer, Sensing agents, Mitochondria-targeting, RNS, reactive nitrogen species, 03 medical and health sciences, MitoQ, TPP-ubiquinone, ROS, reactive oxygen species, In vivo, SkQ1, Skulachev ion-quinone, PTPC, permeability transition pore complex, SOD, superoxide dismutase, MitoChlor, TPP-chlorambucil, αTOS, alpha-tocopheryl succinate, EPR, enhanced permeability and retention, Dequalinium, Arg, arginine, (Fx, r)3, (l-cyclohexyl alanine-d-arginine)3, XO, xanthine oxidase, TEMPOL, 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl, HTPP, 5-(4-hydroxy-phenyl)-10,15,20-triphenylporphyrin, PET, photoinduced electron transfer, lcsh:RM1-950, Tyr, tyrosine, In vitro, mtDNA, mitochondrial DNA, MitoVES, TPP-vitamin E succinate, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, CZBI, carbazole and benzo[e]indolium, Anticancer agents, DEPMPO, 5-(diethylphosphono)-5-methyl-1-pyrroline N-oxide, CAT, catalase, nDNA, nuclear DNA, Conjugate
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المؤلفون: Endre Horvath, Csaba Sumanszki, Csilla Serfozo, Béla Csákány, András Gellért Barta, Péter Reismann, Miklós D. Resch, Zoltán Zsolt Nagy
المصدر: Molecular Genetics and Metabolism Reports, Vol 25, Iss, Pp 100649-(2020)
Molecular Genetics and Metabolism Reportsمصطلحات موضوعية: Intraocular pressure, genetic structures, Dopamine, FLV, focal loss of volume, Nerve fiber layer, ETPKU, early-treated phenylketonuria, PD, Parkinson's disease, OCTA, optical coherence tomography angiography, chemistry.chemical_compound, Endocrinology, ETDRS, early treatment diabetic retinopathy study, VEPs, Visual evoked potentials, Myopia, Contrast (vision), Phenylketonuria, lcsh:QH301-705.5, media_common, lcsh:R5-920, OCT, optical coherence tomography, medicine.diagnostic_test, Phenylalanine level, GCC, ganglion cell layer thickness, LogMAR, logarithm of the minimum angle of resolution, Ganglion, Stereoscopic acuity, VD, vessel density, medicine.anatomical_structure, SD, spectral domain, AL, axial length, D, diopters, Phe, phenylalanine, lcsh:Medicine (General), Research Paper, BCVA, best corrected visual acuity, medicine.medical_specialty, media_common.quotation_subject, PKU, phenylketonuria, GMP, Glycomacropeptide, SE, spherical equivalent, Retinal nerve fiber layer thickness, Ophthalmology, Genetics, medicine, AAS, aminoacid supplements, SWCT, sine wave contrast test, RNFL, retinal nerve fiber layer, Ganglion cell layer thickness, Molecular Biology, Ganglion cell layer, business.industry, BH4, Tetrahydrobiopterine, Retinal, RNFLT, retinal nerve fiber layer thickness, IOP, intraocular pressure, eye diseases, Optical coherence tomography angiography, chemistry, lcsh:Biology (General), Angiography, GLV, global loss of volume, DA, dopamine, sense organs, business
