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المؤلفون: Libby P; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 01915, USA., Pinkosky SL; Esperion Therapeutics, Inc., Ann Arbor, MI 48108, USA., Nissen SE; Cleveland Clinic Coordinating Center for Clinical Research (C5Research), Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA.

المصدر: Cardiovascular research [Cardiovasc Res] 2023 Dec 30; Vol. 119 (17), pp. e160-e163.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: Cholesterol* , Fatty Acids*

المؤلفون: Desjardins EM; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Wu J; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada; Population Health Research Institute, McMaster University, Hamilton, ON L8L 2X2, Canada., Lavoie DCT; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Ahmadi E; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Townsend LK; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Morrow MR; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Wang D; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Tsakiridis EE; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Batchuluun B; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Fayyazi R; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Kwiecien JM; Department of Pathology, McMaster University, Hamilton, ON L8S 4L8, Canada., Tsakiridis T; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Department of Oncology, McMaster University, Hamilton, ON L8S 4L8, Canada., Lally JSV; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Paré G; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Population Health Research Institute, McMaster University, Hamilton, ON L8L 2X2, Canada; Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, ON L8L 2X2, Canada., Pinkosky SL; Esperion Therapeutics, Inc., Ann Arbor, MI, USA., Steinberg GR; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8L 2X2, Canada. Electronic address: gsteinberg@mcmaster.ca.

المصدر: Cell reports. Medicine [Cell Rep Med] 2023 Sep 19; Vol. 4 (9), pp. 101193.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

مواضيع طبية MeSH: Non-alcoholic Fatty Liver Disease*/drug therapy , Insulin Resistance*, Humans ; Animals ; Mice ; Liver Cirrhosis/drug therapy ; Acyltransferases

المؤلفون: Desjardins EM; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada., Smith BK; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada., Day EA; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada., Ducommun S; Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., Lausanne 1015, Switzerland., Sanders MJ; Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., Lausanne 1015, Switzerland., Nederveen JP; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Department of Pediatrics, Faculty of Health Sciences, McMaster University, Hamilton ON L8N 3Z5, Canada., Ford RJ; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada., Pinkosky SL; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada., Townsend LK; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada., Gutgesell RM; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada., Lu R; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada., Sakamoto K; Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., Lausanne 1015, Switzerland.; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen 2200, Denmark., Steinberg GR; Centre for Metabolism Obesity and Diabetes Research, McMaster University, Hamilton ON L8N 3Z5, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton ON L8N 3Z5, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton ON L8N 3Z5, Canada.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Nov 29; Vol. 119 (48), pp. e2119824119. Date of Electronic Publication: 2022 Nov 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Fatty Acids*/metabolism , AMP-Activated Protein Kinases*/genetics , AMP-Activated Protein Kinases*/metabolism, Mice ; Animals ; Phosphorylation ; Mitochondria/metabolism ; Homeostasis ; Autophagy ; Triglycerides/metabolism

المؤلفون: Hallows KR; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States., Li H; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States., Saitta B; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States., Sepehr S; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States., Huang P; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States., Pham J; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States., Wang J; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, United States., Mancino V; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States., Chung EJ; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, United States., Pinkosky SL; Esperion Therapeutics, Ann Arbor, MI, United States., Pastor-Soler NM; Division of Nephrology and Hypertension and USC/UKRO Kidney Research Center, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.

المصدر: Frontiers in molecular biosciences [Front Mol Biosci] 2022 Nov 25; Vol. 9, pp. 1001941. Date of Electronic Publication: 2022 Nov 25 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101653173 Publication Model: eCollection Cited Medium: Print ISSN: 2296-889X (Print) Linking ISSN: 2296889X NLM ISO Abbreviation: Front Mol Biosci Subsets: PubMed not MEDLINE

المؤلفون: Morrow MR; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Batchuluun B; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Wu J; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Ahmadi E; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Leroux JM; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Mohammadi-Shemirani P; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON L8L 2X2, Canada; Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton Health Sciences, Hamilton, ON L8L 2X2, Canada., Desjardins EM; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Wang Z; Department of Molecular & Cellular Endocrinology, Diabetes and Metabolism Research Institute, City of Hope Medical Center, Duarte, CA 91010, USA., Tsakiridis EE; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Lavoie DCT; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Reihani A; Department of Medicine, Division of Respirology, McMaster University and St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada., Smith BK; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Kwiecien JM; Department of Pathology, McMaster University, Hamilton, ON L8S 4L8, Canada., Lally JSV; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada., Nero TL; Structural Biology and Computational Design Laboratory, Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3065, Australia., Parker MW; Structural Biology and Computational Design Laboratory, Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC 3065, Australia; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia., Ask K; Department of Medicine, Division of Respirology, McMaster University and St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada., Scott JW; Protein Chemistry & Metabolism, St. Vincent's Institute of Medical Research and School of Medicine, University of Melbourne, Fitzroy, VIC 3065, Australia; The Florey Institute of Neuroscience and Mental Health, Parkville, VIC 3052, Australia; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, VIC 3052, Australia., Jiang L; Department of Molecular & Cellular Endocrinology, Diabetes and Metabolism Research Institute, City of Hope Medical Center, Duarte, CA 91010, USA; Comprehensive Cancer Center, Beckman Research Institute, City of Hope Medical Center, Duarte, CA 91010, USA., Paré G; Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON L8L 2X2, Canada; Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton Health Sciences, Hamilton, ON L8L 2X2, Canada; Department of Medicine, Division of Respirology, McMaster University and St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON L8S 4L8, Canada., Pinkosky SL; Esperion Therapeutics, Inc., Ann Arbor, MI, USA., Steinberg GR; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, ON L8S 4L8, Canada; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada. Electronic address: gsteinberg@mcmaster.ca.

المصدر: Cell metabolism [Cell Metab] 2022 Jun 07; Vol. 34 (6), pp. 919-936.e8.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE

مواضيع طبية MeSH: ATP Citrate (pro-S)-Lyase*/antagonists & inhibitors , Dyslipidemias*/drug therapy , Dyslipidemias*/pathology , Non-alcoholic Fatty Liver Disease*/drug therapy , Non-alcoholic Fatty Liver Disease*/pathology, Acetyl-CoA Carboxylase ; Animals ; Liver ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/pathology ; Mice ; Oxaloacetates/metabolism ; Triglycerides

المؤلفون: Batchuluun B; Centre for Metabolism, Obesity and Diabetes Research, Department of Medicine and Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada., Pinkosky SL; Esperion Therapeutics, Ann Arbor, MI, USA., Steinberg GR; Centre for Metabolism, Obesity and Diabetes Research, Department of Medicine and Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada. gsteinberg@mcmaster.ca.

المصدر: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2022 Apr; Vol. 21 (4), pp. 283-305. Date of Electronic Publication: 2022 Jan 14.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-1784 (Electronic) Linking ISSN: 14741776 NLM ISO Abbreviation: Nat Rev Drug Discov Subsets: MEDLINE

مواضيع طبية MeSH: ATP Citrate (pro-S)-Lyase*/metabolism , Lipogenesis*, Acetyl-CoA Carboxylase/metabolism ; Fatty Acids ; Humans ; Signal Transduction

المؤلفون: Pinkosky SL; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Scott JW; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.; Mary MacKillop Institute for Health Research, Australian Catholic University, Fitzroy, Victoria, Australia.; The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia., Desjardins EM; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Smith BK; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Day EA; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Ford RJ; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Langendorf CG; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia., Ling NXY; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia., Nero TL; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.; Structural Biology and Computational Design Laboratory, Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia., Loh K; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia., Galic S; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia., Hoque A; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia., Smiles WJ; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia., Ngoei KRW; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia., Parker MW; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.; Structural Biology and Computational Design Laboratory, Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia., Yan Y; Center for Cancer and Cell Biology, Structural Biology Program, Van Andel Research Institute, Grand Rapids, MI, USA., Melcher K; Center for Cancer and Cell Biology, Structural Biology Program, Van Andel Research Institute, Grand Rapids, MI, USA., Kemp BE; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.; Mary MacKillop Institute for Health Research, Australian Catholic University, Fitzroy, Victoria, Australia., Oakhill JS; Mary MacKillop Institute for Health Research, Australian Catholic University, Fitzroy, Victoria, Australia. joakhill@svi.edu.au.; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia. joakhill@svi.edu.au., Steinberg GR; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada. gsteinberg@mcmaster.ca.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada. gsteinberg@mcmaster.ca.

المصدر: Nature metabolism [Nat Metab] 2020 Sep; Vol. 2 (9), pp. 873-881. Date of Electronic Publication: 2020 Jul 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE

مواضيع طبية MeSH: AMP-Activated Protein Kinases/*metabolism , Acyl Coenzyme A/*physiology , Allosteric Regulation/*physiology, AMP-Activated Protein Kinases/chemistry ; AMP-Activated Protein Kinases/genetics ; Animals ; Biphenyl Compounds ; Catalytic Domain ; Esters ; Isoenzymes/chemistry ; Isoenzymes/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Models, Molecular ; Mutation/genetics ; Oxidation-Reduction ; Palmitoyl Coenzyme A/metabolism ; Phosphorylation ; Pyrones/pharmacology ; Thiophenes/pharmacology

المؤلفون: Pinkosky SL; Division of Endocrinology and Metabolism, Department of Medicine, 1280 Main Street West, Hamilton, ON, L8N 3Z5, Canada; Esperion Therapeutics, Inc. 3891 Ranchero Drive, Suite 150, Ann Arbor, MI, 48108, USA., Groot PHE; Esperion Therapeutics, Inc. 3891 Ranchero Drive, Suite 150, Ann Arbor, MI, 48108, USA., Lalwani ND; Esperion Therapeutics, Inc. 3891 Ranchero Drive, Suite 150, Ann Arbor, MI, 48108, USA., Steinberg GR; Division of Endocrinology and Metabolism, Department of Medicine, 1280 Main Street West, Hamilton, ON, L8N 3Z5, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, ON, L8N 3Z5, Canada. Electronic address: gsteinberg@mcmaster.ca.

المصدر: Trends in molecular medicine [Trends Mol Med] 2017 Nov; Vol. 23 (11), pp. 1047-1063. Date of Electronic Publication: 2017 Oct 06.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 100966035 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-499X (Electronic) Linking ISSN: 14714914 NLM ISO Abbreviation: Trends Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: ATP Citrate (pro-S)-Lyase/*metabolism , Hyperlipidemias/*metabolism , Metabolic Diseases/*metabolism, Acetyl Coenzyme A/metabolism ; Animals ; Humans ; Randomized Controlled Trials as Topic