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1دورية أكاديمية
المؤلفون: Holdhoff, Matthias, Kreuzer, Karl-Anton, Appelt, Christine, Scholz, Regina, Na, Il-Kang, Hildebrandt, Bert, Riess, Hanno, Jordan, Andreas, Schmidt, Christian A, Van Etten, Richard A, Dörken, Bernd, le Coutre, Philipp
المصدر: Blood cells, molecules & diseases. 34(2)
مصطلحات موضوعية: Benzamides, Breast Neoplasms, Cell Line, Tumor, Cell Survival: radiation effects, Colonic Neoplasms, Dose-Response Relationship, Radiation, Female, Glioblastoma, Humans, Piperazines: pharmacology, Pyrimidines: pharmacology, Radiation-Sensitizing Agents: pharmacology, Receptors, Platelet-Derived Growth Factor: antagonists & inhibitors
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/0h21427s
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2دورية أكاديمية
المؤلفون: Bellodi, Cristian, Lidonnici, Maria Rosa, Hamilton, Ashley, Helgason, G Vignir, Soliera, Angela Rachele, Ronchetti, Mattia, Galavotti, Sara, Young, Kenneth W, Selmi, Tommaso, Yacobi, Rinat, Van Etten, Richard A, Donato, Nick, Hunter, Ann, Dinsdale, David, Tirrò, Elena, Vigneri, Paolo, Nicotera, Pierluigi, Dyer, Martin J, Holyoake, Tessa, Salomoni, Paolo, Calabretta, Bruno
المصدر: The Journal of clinical investigation. 119(5)
مصطلحات موضوعية: Animals, Antineoplastic Agents: pharmacology, therapeutic use, Autophagy: drug effects, physiology, Benzamides, Calcium: metabolism, Cell Death: drug effects, physiology, Cell Line, Tumor, Chloroquine: pharmacology, therapeutic use, Endoplasmic Reticulum: drug effects, metabolism, Fusion Proteins, bcr-abl: antagonists & inhibitors, genetics, Gene Expression: drug effects, genetics, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: drug therapy, metabolism, pathology, Macrolides: pharmacology, therapeutic use, Mice, Mice, Inbred C3H, Microtubule-Associated Proteins: metabolism, Neoplastic Stem Cells: cytology, drug effects, metabolism, Piperazines: pharmacology, therapeutic use, Protein Kinase Inhibitors: pharmacology, therapeutic use, Protein-Tyrosine Kinases: antagonists & inhibitors, Pyrimidines: pharmacology, therapeutic use, RNA Interference, Thiazoles: pharmacology, therapeutic use, Transcription Factor CHOP: genetics, Xenograft Model Antitumor Assays
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/1pw7d036
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3دورية أكاديمية
المؤلفون: Krause, Daniela S, Van Etten, Richard A
المصدر: Nature medicine. 14(5)
مصطلحات موضوعية: Antineoplastic Agents: pharmacology, therapeutic use, Benzamides, Humans, Interferon Type I: pharmacology, therapeutic use, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: drug therapy, Myeloid Progenitor Cells: cytology, drug effects, Piperazines: pharmacology, therapeutic use, Pyrimidines: pharmacology, therapeutic use, Recombinant Proteins
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/3x54f2j9
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4دورية أكاديمية
المؤلفون: Fedulov, Vadim, Rex, Christopher S, Simmons, Danielle A, Palmer, Linda, Gall, Christine M, Lynch, Gary
المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(30)
مصطلحات موضوعية: Animals, Dendritic Spines: drug effects, physiology, Hippocampus: drug effects, physiology, Learning: drug effects, physiology, Long-Term Potentiation: drug effects, physiology, Male, Piperazines: pharmacology, Rats, Rats, Sprague-Dawley, Synapses: drug effects, physiology
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/5t79h8hs
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5دورية أكاديمية
المؤلفون: Hu, Yiguo, Liu, Yuhua, Pelletier, Shawn, Buchdunger, Elisabeth, Warmuth, Markus, Fabbro, Doriano, Hallek, Michael, Van Etten, Richard A, Li, Shaoguang
المصدر: Nature genetics. 36(5)
مصطلحات موضوعية: Animals, Benzamides, Burkitt Lymphoma: enzymology, pathology, Cell Division: drug effects, Drug Therapy, Combination, Enzyme Activation, Enzyme Inhibitors: pharmacology, Fusion Proteins, bcr-abl: metabolism, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: enzymology, pathology, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, Piperazines: pharmacology, Protein-Tyrosine Kinases: antagonists & inhibitors, physiology, Proto-Oncogene Proteins: antagonists & inhibitors, physiology, Proto-Oncogene Proteins c-hck, Pyrimidines: pharmacology, Pyrroles: pharmacology, src-Family Kinases: antagonists & inhibitors, physiology
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/9pq0v9wm
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6دورية أكاديمية
المؤلفون: Dash, Ajeeta B, Williams, Ifor R, Kutok, Jeffery L, Tomasson, Michael H, Anastasiadou, Ema, Lindahl, Kathleen, Li, Shaoguang, Van Etten, Richard A, Borrow, Julian, Housman, David, Druker, Brian, Gilliland, D Gary
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 99(11)
مصطلحات موضوعية: Animals, Antineoplastic Agents: pharmacology, Benzamides, Blast Crisis: pathology, Bone Marrow Cells: pathology, Bone Marrow Transplantation, Cell Division, Cloning, Molecular, Disease Models, Animal, Disease Progression, Fusion Proteins, bcr-abl: genetics, Green Fluorescent Proteins, Homeodomain Proteins: genetics, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: pathology, Luminescent Proteins: genetics, Mice, Nuclear Pore Complex Proteins: genetics, Oncogene Proteins, Fusion: genetics, Piperazines: pharmacology, Proviruses: genetics, Pyrimidines: pharmacology, Tumor Cells, Cultured
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/9f89s0ps
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7دورية أكاديمية
المؤلفون: Muller, D, Buchs, P A, Dunant, Y, Lynch, G
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 87(11)
مصطلحات موضوعية: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, Animals, Hippocampus: enzymology, Isoquinolines: pharmacology, Membrane Potentials: drug effects, Neuronal Plasticity: physiology, Phorbol Esters: pharmacology, Piperazines: pharmacology, Protein Kinase C: antagonists & inhibitors, physiology, Rats, Receptors, N-Methyl-D-Aspartate, Receptors, Neurotransmitter: physiology, Synaptic Transmission: drug effects, physiology, Time Factors
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/7200790k
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8
المؤلفون: Shun-Qing Liang, Haibin Deng, Ren-Wang Peng, Gregor J. Kocher, Sabina Berezowska, Qinghua Zhou, Zhang Yang, Rémy Bruggmann, Sean Hall, Yanyun Gao, Duo Xu, Thomas M. Marti, Ralph A. Schmid, Haitang Yang
المصدر: Cancer research, vol. 81, no. 11, pp. 3121-3133
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, animal structures, Aged, Animals, Apoptosis, Benzamides/pharmacology, CRISPR-Cas Systems, Cell Cycle, Cell Cycle Proteins/antagonists & inhibitors, Cell Cycle Proteins/genetics, Cell Proliferation, Combined Modality Therapy, Gene Amplification, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms/genetics, Lung Neoplasms/metabolism, Lung Neoplasms/pathology, Lung Neoplasms/therapy, Male, Mice, Piperazines/pharmacology, Protein Kinase Inhibitors/pharmacology, Protein Serine-Threonine Kinases/antagonists & inhibitors, Protein Serine-Threonine Kinases/genetics, Proto-Oncogene Proteins/antagonists & inhibitors, Proto-Oncogene Proteins/genetics, Pyrazoles/pharmacology, Receptor, Fibroblast Growth Factor, Type 1/antagonists & inhibitors, Receptor, Fibroblast Growth Factor, Type 1/genetics, Tumor Cells, Cultured, Xenograft Model Antitumor Assays, Cas9, DNA damage, business.industry, Drug resistance, medicine.disease, PLK1, 3. Good health, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, embryonic structures, Cancer cell, Cancer research, medicine, CRISPR, Kinome, biological phenomena, cell phenomena, and immunity, Lung cancer, business
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3974a8b4da8571f690f7572bb8db80f
https://doi.org/10.1158/0008-5472.can-20-2276 -
9
المؤلفون: Rebekka Koch, Birgit Schioett, Philip C. Biggin, Lucy Kate Ladefoged
المصدر: Ladefoged, L K, Koch, R, Biggin, P C & Schiøtt, B 2022, ' Binding and Activation of Serotonergic G-Protein Coupled Receptors by the Multimodal Antidepressant Vortioxetine ', ACS Chemical Neuroscience, vol. 13, no. 8, pp. 1129-1142 . https://doi.org/10.1021/acschemneuro.1c00029
مصطلحات موضوعية: Agonist, DYNAMICS, Serotonin, medicine.drug_class, Physiology, PREDICTION, 5-HT7, Cognitive Neuroscience, 5-HT, Serotonergic, vortioxetine, Biochemistry, PARAMETERS, Serotonin/metabolism, Piperazines, Receptors, G-Protein-Coupled, GPCR, Vortioxetine/pharmacology, medicine, TOOL, CRYSTAL-STRUCTURE, Piperazines/pharmacology, Mode of action, Receptor, G protein-coupled receptor, Vortioxetine, COUPLED RECEPTORS, Chemistry, Cell Biology, General Medicine, STRUCTURAL INSIGHTS, Ligand (biochemistry), Antidepressive Agents, serotonin, Antidepressive Agents/pharmacology, FORCE-FIELD, Antidepressant, TOLERABILITY, 5-HT1A, 5-HT1B, LIGAND, Neuroscience
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10
المؤلفون: Pancholi, Sunil, Ribas, Ricardo, Simigdala, Nikiana, Schuster, Eugene, Nikitorowicz-Buniak, Joanna, Ressa, Anna, Gao, Qiong, Leal, Mariana Ferreira, Bhamra, Amandeep, Thornhill, Allan, Morisset, Ludivine, Montaudon, Elodie, Sourd, Laura, Fitzpatrick, Martin, Altelaar, Maarten, Johnston, Stephen R, Marangoni, Elisabetta, Dowsett, Mitch, Martin, Lesley-Ann, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
المساهمون: Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
المصدر: Oncogene, 39(25), 4781. Nature Publishing Group
Oncogeneمصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Fulvestrant/administration & dosage, Pyridines, Nude, Drug Resistance, Cyclin-Dependent Kinase 4/genetics, Drug Resistance, Neoplasm/drug effects, Retinoblastoma Protein, Piperazines, Tamoxifen/administration & dosage, Mice, Breast cancer, 0302 clinical medicine, Neoplasm/drug effects, Antineoplastic Combined Chemotherapy Protocols, Receptors, Kinome, Piperazines/pharmacology, Fulvestrant, Inbred BALB C, Pyridines/pharmacology, Mice, Inbred BALB C, Tumor, Cyclin-Dependent Kinase 6/genetics, biology, Receptors, Estrogen/genetics, Cell cycle, Wee1, Receptors, Estrogen, 030220 oncology & carcinogenesis, MCF-7 Cells, Female, RNA Interference, medicine.drug, Mice, Nude, Breast Neoplasms, Breast Neoplasms/genetics, Palbociclib, Antineoplastic Combined Chemotherapy Protocols/pharmacology, Article, Cell Line, 03 medical and health sciences, Cell Line, Tumor, Genetics, medicine, Animals, Humans, Cancer models, Protein Kinase Inhibitors, Molecular Biology, Retinoblastoma Protein/genetics, Cyclin-Dependent Kinase 4, Estrogen/genetics, Cyclin-Dependent Kinase 6, Xenograft Model Antitumor Assays, Tamoxifen, 030104 developmental biology, Xenograft Model Antitumor Assays/methods, Drug Resistance, Neoplasm, Protein Kinase Inhibitors/pharmacology, biology.protein, Cancer research, TSC2
وصف الملف: application/pdf