المؤلفون: Pippione, Ac, Sainas, S, Giraudo, A, Bonanni, D, Villella, N, Bertea, C, Friemann, R, Al-Karadaghi, S, Boschi, D, Lolli, Ml.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______970::21fb054eed07a7b551c48f7c77f07541
https://hdl.handle.net/2318/1720097

المؤلفون: Pippione AC; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Kovachka S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA., Vigato C; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Bertarini L; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy; Department of Life Sciences, University of Modena and Reggio Emilia, via Campi 103, 41125, Modena, Italy., Mannella I; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Sainas S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Rolando B; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Denasio E; Institute of Cancer Therapeutics, Faculty of Life Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK., Piercy-Mycock H; Institute of Cancer Therapeutics, Faculty of Life Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK., Romalho L; Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, DK-2100, Copenhagen, Denmark., Salladini E; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Adinolfi S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Zonari D; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Peraldo-Neia C; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy., Chiorino G; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy., Passoni A; Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156, Milan, Italy., Mirza OA; Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, DK-2100, Copenhagen, Denmark., Frydenvang K; Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, DK-2100, Copenhagen, Denmark., Pors K; Institute of Cancer Therapeutics, Faculty of Life Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK., Lolli ML; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Spyrakis F; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Oliaro-Bosso S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy. Electronic address: simona.oliaro@unito.it., Boschi D; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy. Electronic address: donatella.boschi@unito.it.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Mar 15; Vol. 268, pp. 116193. Date of Electronic Publication: 2024 Feb 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Prostatic Neoplasms*/drug therapy, Male ; Humans ; Aldo-Keto Reductase Family 1 Member C3 ; 3-Hydroxysteroid Dehydrogenases/metabolism ; Hydroxyprostaglandin Dehydrogenases/metabolism ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/chemistry

المؤلفون: Wróbel TM; Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Medical University of Lublin, Chodźki 4a, 20093 Lublin, Poland.; Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Sharma K; Department of Pediatrics, Division of Endocrinology, Diabetology and Metabolism, University Children's Hospital, University of Bern, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Bern, Switzerland., Mannella I; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Oliaro-Bosso S; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Nieckarz P; Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Medical University of Lublin, Chodźki 4a, 20093 Lublin, Poland., Du Toit T; Department of Pediatrics, Division of Endocrinology, Diabetology and Metabolism, University Children's Hospital, University of Bern, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland., Voegel CD; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.; Department of Nephrology and Hypertension, University Hospital Inselspital, University of Bern, 3010 Bern, Switzerland., Rojas Velazquez MN; Department of Pediatrics, Division of Endocrinology, Diabetology and Metabolism, University Children's Hospital, University of Bern, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Bern, Switzerland., Yakubu J; Department of Pediatrics, Division of Endocrinology, Diabetology and Metabolism, University Children's Hospital, University of Bern, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Bern, Switzerland., Matveeva A; Department of Pediatrics, Division of Endocrinology, Diabetology and Metabolism, University Children's Hospital, University of Bern, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Bern, Switzerland., Therkelsen S; Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Jørgensen FS; Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark., Pandey AV; Department of Pediatrics, Division of Endocrinology, Diabetology and Metabolism, University Children's Hospital, University of Bern, 3010 Bern, Switzerland.; Translational Hormone Research Program, Department of Biomedical Research, University of Bern, 3010 Bern, Switzerland., Pippione AC; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Lolli ML; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Boschi D; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Björkling F; Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 160, 2100 Copenhagen, Denmark.

المصدر: Biomolecules [Biomolecules] 2023 Sep 05; Vol. 13 (9). Date of Electronic Publication: 2023 Sep 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Nitrogen* , Sulfur*, Secondary Metabolism

المؤلفون: Sainas S; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Giorgis M; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Circosta P; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin 10043, Italy.; Molecular Biotechnology Center, University of Turin, Via Nizza 52, Turin 10126, Italy., Poli G; Department of Pharmacy, University of Pisa, Via Bonanno 6, Pisa 56126, Italy., Alberti M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, Novara 28100, Italy., Passoni A; Laboratory of Mass Spectrometry, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy., Gaidano V; Division of Hematology and Cell Therapy, AO Ordine Mauriziano, Largo Filippo Turati, 62, Turin 10128, Italy., Pippione AC; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Vitale N; Department of Molecular Biotechnology and Health Sciences, University of Turin, Via Nizza 52, Turin 10126, Italy., Bonanni D; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy.; Life Science Department, University of Modena, Via Università 4, Modena 41121, Italy., Rolando B; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Cignetti A; Division of Hematology and Cell Therapy, AO Ordine Mauriziano, Largo Filippo Turati, 62, Turin 10128, Italy., Ramondetti C; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Lanno A; Laboratory of Mass Spectrometry, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy., Ferraris DM; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, Novara 28100, Italy., Canepa B; GEM FORLAB, Via Ing. Comotto 36, Caluso, Turin, 10014, Italy., Buccinnà B; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Piccinini M; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Rizzi M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, Novara 28100, Italy., Saglio G; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin 10043, Italy.; Division of Hematology and Cell Therapy, AO Ordine Mauriziano, Largo Filippo Turati, 62, Turin 10128, Italy., Al-Karadaghi S; Department of Biochemistry and Structural Biology, Lund University, Naturvetarvägen 14, Box 124, Lund 221 00, Sweden., Boschi D; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Miggiano R; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Via G. Bovio 6, Novara 28100, Italy., Tuccinardi T; Molecular Biotechnology Center, University of Turin, Via Nizza 52, Turin 10126, Italy., Lolli ML; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy.

المصدر: Journal of medicinal chemistry [J Med Chem] 2022 Oct 13; Vol. 65 (19), pp. 12701-12724. Date of Electronic Publication: 2022 Sep 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/drug therapy , Oxidoreductases Acting on CH-CH Group Donors*, Animals ; Humans ; Mice ; Antiviral Agents/pharmacology ; Dihydroorotate Dehydrogenase ; Dipyridamole/therapeutic use ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Structure-Activity Relationship

المؤلفون: Pippione AC; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Kilic-Kurt Z; Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara, Turkey., Kovachka S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Sainas S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Rolando B; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Denasio E; Institute of Cancer Therapeutics, Faculty of Life Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK., Pors K; Institute of Cancer Therapeutics, Faculty of Life Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK., Adinolfi S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Zonari D; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Bagnati R; Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, via Mario Negri 2, 20156, Milan, Italy., Lolli ML; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Spyrakis F; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy. Electronic address: francesca.spyrakis@unito.it., Oliaro-Bosso S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy. Electronic address: simona.oliaro@unito.it., Boschi D; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy. Electronic address: donatella.boschi@unito.it.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2022 Jul 05; Vol. 237, pp. 114366. Date of Electronic Publication: 2022 Apr 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Aldo-Keto Reductase Family 1 Member C3*/antagonists & inhibitors , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Prostatic Neoplasms, Castration-Resistant*/drug therapy, Androgens ; Humans ; Male

المؤلفون: Rubin E; Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 8410501, Israel., Pippione AC; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Boyko M; Department of Anesthesiology and Critical Care, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel., Einaudi G; Pharmacology Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy., Sainas S; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Collino M; Department of Neuroscience 'Rita Levi Montalcini', University of Turin, 10125 Turin, Italy., Cifani C; Pharmacology Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy., Lolli ML; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Abu-Freha N; Institute of Gastroenterology and Hepatology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel., Kaplanski J; Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 8410501, Israel., Boschi D; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy., Azab AN; Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 8410501, Israel.; Department of Nursing, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 8410501, Israel.

المصدر: Brain sciences [Brain Sci] 2021 Dec 28; Vol. 12 (1). Date of Electronic Publication: 2021 Dec 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101598646 Publication Model: Electronic Cited Medium: Print ISSN: 2076-3425 (Print) Linking ISSN: 20763425 NLM ISO Abbreviation: Brain Sci Subsets: PubMed not MEDLINE

المؤلفون: Sainas S; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Giorgis M; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Circosta P; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin 10043, Italy.; Molecular Biotechnology Center, University of Turin, Via Nizza 52, Turin 10126, Italy., Gaidano V; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin 10043, Italy.; Division of Hematology, AO SS Antonio e Biagio e Cesare Arrigo, Via Venezia 16, Alessandria 15121, Italy., Bonanni D; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Pippione AC; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Bagnati R; Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milano 20156, Italy., Passoni A; Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milano 20156, Italy., Qiu Y; Laboratory of Tumor Microenvironment, Candiolo Cancer Institute, FPO, IRCCS, Candiolo, Strada Provinciale, 142-KM 3.95, Candiolo, Turin 10060, Italy.; Higher Education Mega Center, Institutes for Life Sciences, South China University of Technology, Guangzhou 510641, China., Cojocaru CF; Laboratory of Tumor Microenvironment, Candiolo Cancer Institute, FPO, IRCCS, Candiolo, Strada Provinciale, 142-KM 3.95, Candiolo, Turin 10060, Italy., Canepa B; Gem Forlab srl, Via Ribes, 5, Colleretto Giacosa, Turin 10010, Italy., Bona A; Gem Chimica srl, Via Maestri del Lavoro, 25, Busca, Cuneo 12022, Italy., Rolando B; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Mishina M; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Ramondetti C; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Buccinnà B; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Piccinini M; Department of Oncology, University of Turin, Via Michelangelo 27/B, Turin 10125, Italy., Houshmand M; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin 10043, Italy.; Molecular Biotechnology Center, University of Turin, Via Nizza 52, Turin 10126, Italy., Cignetti A; Division of Hematology and Cell Therapy, AO Ordine Mauriziano, Largo Filippo Turati, 62, Turin 10128, Italy., Giraudo E; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy.; Laboratory of Tumor Microenvironment, Candiolo Cancer Institute, FPO, IRCCS, Candiolo, Strada Provinciale, 142-KM 3.95, Candiolo, Turin 10060, Italy., Al-Karadaghi S; Department of Biochemistry and Structural Biology, Lund University, Naturvetarvägen 14, Box 124, Lund 221 00, Sweden., Boschi D; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy., Saglio G; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, Orbassano, Turin 10043, Italy.; Division of Hematology and Cell Therapy, AO Ordine Mauriziano, Largo Filippo Turati, 62, Turin 10128, Italy., Lolli ML; Department of Drug Science and Technology, University of Turin, Via P. Giuria 9, Turin 10125, Italy.

المصدر: Journal of medicinal chemistry [J Med Chem] 2021 May 13; Vol. 64 (9), pp. 5404-5428. Date of Electronic Publication: 2021 Apr 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Biphenyl Compounds/*chemistry , Enzyme Inhibitors/*chemistry , Oxidoreductases Acting on CH-CH Group Donors/*antagonists & inhibitors , Pyrazoles/*chemistry , Pyridines/*chemistry, Animals ; Apoptosis/drug effects ; Binding Sites ; Cell Differentiation/drug effects ; Cell Line, Tumor ; Dihydroorotate Dehydrogenase ; Drug Design ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; Female ; Half-Life ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Male ; Mice ; Mice, Inbred BALB C ; Microsomes, Liver/metabolism ; Molecular Docking Simulation ; Oxidoreductases Acting on CH-CH Group Donors/metabolism ; Pyrazoles/metabolism ; Pyrazoles/pharmacology ; Pyrazoles/therapeutic use ; Pyridines/metabolism ; Pyridines/pharmacology ; Pyridines/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Structure-Activity Relationship

المؤلفون: Luganini A; Department of Life Sciences and Systems Biology, 10123, Turin, Italy., Sibille G; Department of Life Sciences and Systems Biology, 10123, Turin, Italy., Mognetti B; Department of Life Sciences and Systems Biology, 10123, Turin, Italy., Sainas S; Department of Sciences and Drug Technology, University of Turin, 10125, Turin, Italy., Pippione AC; Department of Sciences and Drug Technology, University of Turin, 10125, Turin, Italy., Giorgis M; Department of Sciences and Drug Technology, University of Turin, 10125, Turin, Italy., Boschi D; Department of Sciences and Drug Technology, University of Turin, 10125, Turin, Italy., Lolli ML; Department of Sciences and Drug Technology, University of Turin, 10125, Turin, Italy., Gribaudo G; Department of Life Sciences and Systems Biology, 10123, Turin, Italy. Electronic address: giorgio.gribaudo@unito.it.

المصدر: Antiviral research [Antiviral Res] 2021 May; Vol. 189, pp. 105057. Date of Electronic Publication: 2021 Mar 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , Herpes Simplex/*drug therapy , Herpesvirus 1, Human/*drug effects , Herpesvirus 2, Human/*drug effects , Oxidoreductases Acting on CH-CH Group Donors/*antagonists & inhibitors , Virus Replication/*drug effects, Acyclovir/pharmacology ; Animals ; Cell Line, Tumor ; Chlorocebus aethiops ; DNA Replication/drug effects ; DNA, Viral/biosynthesis ; Dihydroorotate Dehydrogenase ; Drug Synergism ; Drug Therapy, Combination ; Gene Expression Regulation, Viral/drug effects ; Herpes Simplex/virology ; Humans ; Pyrimidines/biosynthesis ; Vero Cells

المؤلفون: Peraldo-Neia C; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy., Ostano P; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy., Mello-Grand M; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy., Guana F; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy., Gregnanin I; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy., Boschi D; Department of Drug Science and Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Oliaro-Bosso S; Department of Drug Science and Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Pippione AC; Department of Drug Science and Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy., Carenzo A; Integrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy., De Cecco L; Integrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy., Cavalieri S; Head and Neck Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy., Micali A; Integrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy., Perrone F; Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy., Averono G; Otorhinolaryngology Unit, Ospedale degli Infermi, via dei Ponderanesi 1, Ponderano, Biella, Italy., Bagnasacco P; Otorhinolaryngology Unit, Ospedale degli Infermi, via dei Ponderanesi 1, Ponderano, Biella, Italy., Dosdegani R; Otorhinolaryngology Unit, Ospedale Sant'Andrea, Vercelli, Italy., Masini L; Department of Translational Medicine, UPO School of Medicine, Radiotherapy Unit, Novara, Italy., Krengli M; Department of Translational Medicine, UPO School of Medicine, Radiotherapy Unit, Novara, Italy., Aluffi-Valletti P; Department of Health Sciences, UPO School of Medicine, Otorhinolaryngology Unit, Novara, Italy., Valente G; Department of Translational Medicine, UPO School of Medicine, Radiotherapy Unit, Novara, Italy., Chiorino G; Laboratory of Cancer Genomics, Fondazione Edo ed Elvo Tempia, via Malta 3, 13900, Biella, Italy. giovanna.chiorino@fondazionetempia.org.

المصدر: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2021 Apr; Vol. 44 (2), pp. 357-372. Date of Electronic Publication: 2020 Nov 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 101552938 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3436 (Electronic) Linking ISSN: 22113428 NLM ISO Abbreviation: Cell Oncol (Dordr) Subsets: MEDLINE

مواضيع طبية MeSH: Aldo-Keto Reductase Family 1 Member C3/*metabolism , Biomarkers, Tumor/*metabolism , Oropharyngeal Neoplasms/*metabolism, Aged ; Aged, 80 and over ; Aldo-Keto Reductase Family 1 Member C3/genetics ; Biomarkers, Tumor/genetics ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/virology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Survival/drug effects ; Cisplatin/pharmacology ; Down-Regulation/genetics ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Gene Regulatory Networks ; Humans ; Male ; Middle Aged ; Oropharyngeal Neoplasms/genetics ; Oropharyngeal Neoplasms/pathology ; Oropharyngeal Neoplasms/virology ; Papillomavirus Infections/complications ; Prognosis ; Up-Regulation/genetics

المؤلفون: Gaidano V; Department of Clinical and Biological Sciences, University of Turin, Orbassano, 10043 Turin, Italy.; Division of Hematology, A.O. SS Antonio e Biagio e Cesare Arrigo, 15121 Alessandria, Italy., Houshmand M; Department of Clinical and Biological Sciences, University of Turin, Orbassano, 10043 Turin, Italy.; Molecular Biotechnology Center, University of Turin, 10126 Turin, Italy., Vitale N; Molecular Biotechnology Center, University of Turin, 10126 Turin, Italy.; Department of Medical Sciences, University of Turin, 10124 Turin, Italy., Carrà G; Department of Clinical and Biological Sciences, University of Turin, Orbassano, 10043 Turin, Italy.; Molecular Biotechnology Center, University of Turin, 10126 Turin, Italy., Morotti A; Department of Clinical and Biological Sciences, University of Turin, Orbassano, 10043 Turin, Italy., Tenace V; Department of Electrical and Computer Engineering, University of Utah, Salt Lake City, UT 84112, USA., Rapelli S; Department of Life Sciences and System Biology, University of Turin, 10124 Turin, Italy., Sainas S; Department of Drug Science and Technology, University of Turin, 10124 Turin, Italy., Pippione AC; Department of Drug Science and Technology, University of Turin, 10124 Turin, Italy., Giorgis M; Department of Drug Science and Technology, University of Turin, 10124 Turin, Italy., Boschi D; Department of Drug Science and Technology, University of Turin, 10124 Turin, Italy., Lolli ML; Department of Drug Science and Technology, University of Turin, 10124 Turin, Italy., Cilloni D; Department of Clinical and Biological Sciences, University of Turin, Orbassano, 10043 Turin, Italy.; University Division of Hematology and Cell Therapy, A.O. Ordine Mauriziano, University of Turin, 10128 Turin, Italy., Cignetti A; University Division of Hematology and Cell Therapy, A.O. Ordine Mauriziano, University of Turin, 10128 Turin, Italy., Saglio G; Department of Clinical and Biological Sciences, University of Turin, Orbassano, 10043 Turin, Italy.; University Division of Hematology and Cell Therapy, A.O. Ordine Mauriziano, University of Turin, 10128 Turin, Italy., Circosta P; Department of Clinical and Biological Sciences, University of Turin, Orbassano, 10043 Turin, Italy.; Molecular Biotechnology Center, University of Turin, 10126 Turin, Italy.

المصدر: Cancers [Cancers (Basel)] 2021 Feb 28; Vol. 13 (5). Date of Electronic Publication: 2021 Feb 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE