المؤلفون: Brown BA; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia., Myers PJ; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia., Adair SJ; Department of Surgery, University of Virginia, Charlottesville, Virginia., Pitarresi JR; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Sah-Teli SK; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland., Campbell LA; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia., Hart WS; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia., Barbeau MC; Biomedical Sciences, University of Virginia, Charlottesville, Virginia., Leong K; Engineering Science, University of Virginia, Charlottesville, Virginia., Seyler N; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia., Kane W; Department of Surgery, University of Virginia, Charlottesville, Virginia., Lee KE; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan., Stelow E; Department of Pathology, University of Virginia, Charlottesville, Virginia., Jones M; Claude Moore Health Sciences Library, University of Virginia, Charlottesville, Virginia., Simon MC; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania., Koivunen P; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland., Bauer TW; Department of Surgery, University of Virginia, Charlottesville, Virginia., Stanger BZ; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Lazzara MJ; Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia.; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.

المصدر: Cancer research [Cancer Res] 2024 Jun 04; Vol. 84 (11), pp. 1764-1780.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Epithelial-Mesenchymal Transition* , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Pancreatic Neoplasms*/drug therapy , Histones*/metabolism , Carcinoma, Pancreatic Ductal*/pathology , Carcinoma, Pancreatic Ductal*/metabolism , Carcinoma, Pancreatic Ductal*/drug therapy, Humans ; Mice ; Animals ; Methylation ; MAP Kinase Signaling System ; Cell Line, Tumor ; Tumor Microenvironment ; Mice, Nude ; Xenograft Model Antitumor Assays ; Cell Hypoxia ; Tumor Hypoxia ; Hypoxia/metabolism ; F-Box Proteins ; Jumonji Domain-Containing Histone Demethylases

المؤلفون: Pitarresi JR; Division of Hematology and Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01655, USA.; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01655, USA., Stanger BZ; Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA bstanger@upenn.edu.

المصدر: Cold Spring Harbor perspectives in medicine [Cold Spring Harb Perspect Med] 2024 Jun 03; Vol. 14 (6). Date of Electronic Publication: 2024 Jun 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 101571139 Publication Model: Electronic Cited Medium: Internet ISSN: 2157-1422 (Electronic) Linking ISSN: 21571422 NLM ISO Abbreviation: Cold Spring Harb Perspect Med Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/genetics , Neoplasms*/pathology , Cell Lineage*, Animals ; Humans ; Mice ; Disease Models, Animal ; Cell Plasticity/genetics ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/pathology ; Epigenesis, Genetic ; Carcinogenesis/genetics

المؤلفون: Chibaya L; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Lusi CF; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA USA., DeMarco KD; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Kane GI; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA USA., Brassil ML; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA USA., Parikh CN; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Murphy KC; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Li J; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Naylor TE; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA USA., Cerrutti J; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA USA., Peura J; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Division of Hematology-Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Pitarresi JR; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Division of Hematology-Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Zhu LJ; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Program in Bioinformatics and Integrative Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Fitzgerald KA; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Atukorale PU; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA USA.; Division of Innate Immunity, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Cancer Center, University of Massachusetts Chan Medical School, Worcester, MA. USA., Ruscetti M; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.; Cancer Center, University of Massachusetts Chan Medical School, Worcester, MA. USA.; Immunology and Microbiology Program, University of Massachusetts Chan Medical School, Worcester, MA, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 18. Date of Electronic Publication: 2023 Sep 18.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Fernandez Garcia E; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Paudel U; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Noji MC; Department of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Department of Medicine, Perelman School of Medicine, Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, United States., Bowman CE; Department of Medicine, Perelman School of Medicine, Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, United States., Rustgi AK; Division of Digestive and Liver Diseases, Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States., Pitarresi JR; Division of Hematology/Oncology, Departments of Medicine and Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, United States., Wellen KE; Department of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Arany Z; Department of Medicine, Perelman School of Medicine, Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, United States., Weissenrieder JS; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States., Foskett JK; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

المصدر: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Jun 08; Vol. 11, pp. 1082213. Date of Electronic Publication: 2023 Jun 08 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

المؤلفون: Perez K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chiarella AM; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA., Cleary JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Horick N; Biostatistics Center, Massachusetts General Hospital, Boston, MA, USA., Weekes C; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Abrams T; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Blaszkowsky L; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Enzinger P; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Giannakis M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Goyal L; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Meyerhardt JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Rubinson D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Yurgelun MB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Goessling W; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Giantonio BJ; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Brais L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Germon V; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Stonely D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Raghavan S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Bakir B; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA., Das K; Division of Gastroenterology, Washington University School of Medicine, St. Louis, MO, USA., Pitarresi JR; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Aguirre AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Needle M; AVEO Oncology, Cambridge, MA, USA., Rustgi AK; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.

المصدر: The oncologist [Oncologist] 2023 May 08; Vol. 28 (5), pp. 425-432.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

مواضيع طبية MeSH: Hypoalbuminemia*/chemically induced , Pancreatic Neoplasms*/pathology, Humans ; Male ; Female ; Aged ; Gemcitabine ; Albumin-Bound Paclitaxel ; Paclitaxel/adverse effects ; Albumins/adverse effects ; Edema/etiology ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Pancreatic Neoplasms

المؤلفون: García EF; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Paudel U; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Noji MC; Department of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Cardiovascular Institute, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Bowman CE; Cardiovascular Institute, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pitarresi JR; Division of Hematology/Oncology, Departments of Medicine and Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Rustgi AK; Division of Digestive and Liver Diseases, Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA., Wellen KE; Department of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Arany Z; Cardiovascular Institute, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Weissenrieder JS; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Foskett JK; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Apr 28. Date of Electronic Publication: 2023 Apr 28.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: McBrearty N; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Cho C; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Chen J; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Zahedi F; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Peck AR; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin., Radaelli E; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Assenmacher CA; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Pavlak C; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Devine A; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Yu P; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Lu Z; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Zhang H; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Li J; Department of Pathology and Laboratory Medicine, Perelman School of Medicine and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania., Pitarresi JR; Department of Pathology and Laboratory Medicine, Perelman School of Medicine and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania., Astsaturov I; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Cukierman E; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Rustgi AK; Division of Digestive and Liver Diseases, Department of Medicine, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York., Stanger BZ; Department of Pathology and Laboratory Medicine, Perelman School of Medicine and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania., Rui H; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin., Fuchs SY; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2023 Mar 01; Vol. 21 (3), pp. 228-239.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Pancreatic Ductal*/pathology , Pancreatic Neoplasms*/pathology , Steroid Hydroxylases*/metabolism, Animals ; Humans ; Mice ; Mice, Knockout

المؤلفون: Barry-Hundeyin M; Markey Cancer Center, University of Kentucky, Lexington, KY, USA. mhu297@uky.edu., Carrot-Zhang J; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. carrotj@mskcc.org., Dayton T; Tissue Biology and Disease Modeling Unit, European Molecular Biology Lab, Barcelona, Spain. talya.dayton@embl.es., Ghazanfar S; School of Mathematics and Statistics, University of Sydney, Sydney, New South Wales, Australia. shila.ghazanfar@sydney.edu.au.; Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia. shila.ghazanfar@sydney.edu.au., Guenther LM; St. Jude Children's Research Hospital, Memphis, TN, USA. lily.guenther@stjude.org., Nguyen DTT; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK. t.d.nguyen@qmul.ac.uk., Pitarresi JR; Division of Hematology and Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA. Jason.Pitarresi@umassmed.edu.; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA. Jason.Pitarresi@umassmed.edu., Rajput S; Centre for Regenerative Medicine & Stem Cell Research, The Aga Khan University, Karachi, Pakistan. sheerien.rajput@aku.edu., Santana-Codina N; Department of Biomedicine, Aarhus University, Aarhus, Denmark. nsc@biomed.au.dk., Shree T; Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health and Sciences University, Portland, OR, USA. shree@ohsu.edu., Zeng Z; Center for Quantitative Biology, Peking University, Beijing, China. zexianzeng@pku.edu.cn.; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China. zexianzeng@pku.edu.cn., Zhang Y; School of Life Sciences, Peking University, Beijing, China. ying.zhang@pku.edu.cn.

المصدر: Nature cancer [Nat Cancer] 2022 Dec; Vol. 3 (12), pp. 1426-1431.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Lefler JE; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., MarElia-Bennett CB; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Thies KA; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Hildreth BE 3rd; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Sharma SM; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Pitarresi JR; Division of Gastroenterology, Department of Medicine and Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA., Han L; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Everett C; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Koivisto C; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Cuitino MC; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Timmers CD; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., O'Quinn E; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Parrish M; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Romeo MJ; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Linke AJ; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Hobbs GA; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA., Leone G; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, USA., Guttridge DC; Department of Pediatrics and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA., Zimmers TA; Department of Anatomy, Cell Biology, and Physiology, Indiana University School of Medicine, Indianapolis, IN, USA., Lesinski GB; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA., Ostrowski MC; Hollings Cancer Center and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA ostrowsk@musc.edu.

المصدر: Life science alliance [Life Sci Alliance] 2022 Jul 08; Vol. 5 (11). Date of Electronic Publication: 2022 Jul 08 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Pancreatic Ductal*/metabolism , Pancreatic Neoplasms*/metabolism, Animals ; CD8-Positive T-Lymphocytes/metabolism ; Cell Line, Tumor ; Fibroblasts/metabolism ; Mice ; Tumor Microenvironment

المؤلفون: Maddipati R; Department of Internal Medicine and Children's Research Institute, UT Southwestern Medical Center, Dallas, Texas. Ravikanth.Maddipati@UTsouthwestern.edu bstanger@upenn.edu.; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas., Norgard RJ; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., Baslan T; Cancer Biology and Genetics Program, Sloan Kettering Institute, New York, New York., Rathi KS; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Biomedical and Health informatics and Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Zhang A; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Saeid A; Department of Internal Medicine and Children's Research Institute, UT Southwestern Medical Center, Dallas, Texas., Higashihara T; Department of Internal Medicine and Children's Research Institute, UT Southwestern Medical Center, Dallas, Texas., Wu F; Department of Internal Medicine and Children's Research Institute, UT Southwestern Medical Center, Dallas, Texas., Kumar A; Department of Internal Medicine and Children's Research Institute, UT Southwestern Medical Center, Dallas, Texas., Annamalai V; Department of Internal Medicine and Children's Research Institute, UT Southwestern Medical Center, Dallas, Texas., Bhattacharya S; Department of Internal Medicine and Children's Research Institute, UT Southwestern Medical Center, Dallas, Texas., Raman P; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Biomedical and Health informatics and Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Adkisson CA; Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Pitarresi JR; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., Wengyn MD; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., Yamazoe T; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., Li J; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., Balli D; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., LaRiviere MJ; Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania., Ngo TC; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas., Folkert IW; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.; Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania., Millstein ID; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania., Bermeo J; Cancer Biology and Genetics Program, Sloan Kettering Institute, New York, New York.; The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York., Carpenter EL; Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., McAuliffe JC; Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Oktay MH; Department of Pathology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Brekken RA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas., Lowe SW; Cancer Biology and Genetics Program, Sloan Kettering Institute, New York, New York., Iacobuzio-Donahue CA; The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York., Notta F; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Stanger BZ; Division of Gastroenterology, Department of Medicine, Penn Pancreatic Cancer Research Center and Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania. Ravikanth.Maddipati@UTsouthwestern.edu bstanger@upenn.edu.; Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

المصدر: Cancer discovery [Cancer Discov] 2022 Feb; Vol. 12 (2), pp. 542-561. Date of Electronic Publication: 2021 Sep 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic* , Genes, myc* , Neoplasm Metastasis*, Adenocarcinoma/*genetics , Carcinoma, Pancreatic Ductal/*genetics , Pancreatic Neoplasms/*genetics, Adenocarcinoma/secondary ; Animals ; Carcinoma, Pancreatic Ductal/secondary ; Disease Models, Animal ; Humans ; Mice ; Pancreatic Neoplasms/pathology