المؤلفون: Robert V. Stahelin, Monica L. Husby, Emily A. David, Plescia Cb, Laura I. Prugar, Souad Amiar, John M. Dye, Kathleen E. Huie, Elsje Pienaar, Jennifer M. Brannan

مصطلحات موضوعية: VP40, Fendiline, Ebola virus, Viral matrix protein, Viral envelope, Chemistry, Viral entry, viruses, Viral budding, medicine, Viral shedding, medicine.disease_cause, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e54f7ba2a36f7436775de2828fea477
https://doi.org/10.1101/2021.06.08.447555

المؤلفون: Dutta M; Department of Chemistry, The University of Chicago, Chicago, Illinois, USA., Su Y; Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana, USA., Plescia CB; Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana, USA., Voth GA; Department of Chemistry, The University of Chicago, Chicago, Illinois, USA; Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Frank Institute, The University of Chicago, Chicago, Illinois, USA. Electronic address: gavoth@uchicago.edu., Stahelin RV; Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana, USA. Electronic address: rstaheli@purdue.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 Jun 10; Vol. 300 (8), pp. 107456. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

المؤلفون: Sanford LM; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States., Keiser P; Department of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, 02118, United States., Fujii N; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States., Woods H; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States., Zhang C; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States; Department of Industrial and Molecular Pharmaceutics, Purdue University, West Lafayette, IN, 47907, United States., Xu Z; Department of Industrial and Molecular Pharmaceutics, Purdue University, West Lafayette, IN, 47907, United States., Mahajani NS; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States., Cortés JG; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States., Plescia CB; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States., Knipp G; Department of Industrial and Molecular Pharmaceutics, Purdue University, West Lafayette, IN, 47907, United States., Stahelin RV; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States., Davey R; Department of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, 02118, United States., Davisson VJ; Borch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, United States. Electronic address: davisson@purdue.edu.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Sep 05; Vol. 275, pp. 116537. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Vacuolar Proton-Translocating ATPases*/antagonists & inhibitors , Vacuolar Proton-Translocating ATPases*/metabolism , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Antiviral Agents*/pharmacokinetics , Antiviral Agents*/chemical synthesis, Animals ; Mice ; Structure-Activity Relationship ; Humans ; Molecular Structure ; Ebolavirus/drug effects ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/pharmacokinetics ; Dose-Response Relationship, Drug ; Lignans/pharmacology ; Lignans/chemistry ; Naphthalenes/pharmacology ; Naphthalenes/chemistry ; Naphthalenes/pharmacokinetics ; Naphthalenes/chemical synthesis ; Virus Internalization/drug effects

المؤلفون: Husby ML; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.; Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), Purdue University, West Lafayette, West Lafayette, IN, USA., Amiar S; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.; Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), Purdue University, West Lafayette, West Lafayette, IN, USA., Prugar LI; United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Frederick, MD, USA., David EA; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA., Plescia CB; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA., Huie KE; United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Frederick, MD, USA., Brannan JM; United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Frederick, MD, USA., Dye JM; United States Army Medical Research Institute of Infectious Diseases USAMRIID, Fort Detrick, Frederick, MD, USA., Pienaar E; Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), Purdue University, West Lafayette, West Lafayette, IN, USA.; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA., Stahelin RV; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.; Purdue Institute of Inflammation, Immunology and Infectious Disease (PI4D), Purdue University, West Lafayette, West Lafayette, IN, USA.

المصدر: EMBO reports [EMBO Rep] 2022 Nov 07; Vol. 23 (11), pp. e51709. Date of Electronic Publication: 2022 Sep 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

مواضيع طبية MeSH: Hemorrhagic Fever, Ebola*/metabolism , Ebolavirus*/physiology, Animals ; Phosphatidylserines/metabolism ; Fendiline/metabolism ; Viral Matrix Proteins/metabolism ; Virus Assembly ; Cluster Analysis ; Mammals/metabolism

المؤلفون: Plescia CB, Lindstrom AR, Quintero MV; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio 78229-3900, United States., Keiser P; Department of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts 02118, United States., Anantpadma M; Department of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts 02118, United States., Davey R; Department of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts 02118, United States., Stahelin RV, Davisson VJ

المصدر: ACS infectious diseases [ACS Infect Dis] 2022 May 13; Vol. 8 (5), pp. 942-957. Date of Electronic Publication: 2022 Mar 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Ebolavirus* , Hemorrhagic Fever, Ebola*/drug therapy, Benzodioxoles/pharmacology ; Humans ; Lignans ; Phenol/pharmacology ; Phenol/therapeutic use ; Virus Internalization

المؤلفون: Plescia CB; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, Indiana, USA., David EA; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, Indiana, USA., Patra D; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, Indiana, USA., Sengupta R; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, Indiana, USA., Amiar S; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, Indiana, USA., Su Y; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, Indiana, USA., Stahelin RV; Department of Medicinal Chemistry & Molecular Pharmacology, Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, Indiana, USA. Electronic address: rstaheli@purdue.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100103. Date of Electronic Publication: 2020 Nov 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Coronavirus Envelope Proteins/*genetics , Nucleocapsid Proteins/*genetics , SARS-CoV-2/*growth & development , Spike Glycoprotein, Coronavirus/*genetics , Viral Matrix Proteins/*genetics , Virion/*growth & development, Biomimetic Materials/chemistry ; Biomimetic Materials/metabolism ; Containment of Biohazards/classification ; Coronavirus Envelope Proteins/metabolism ; Gene Expression ; Genes, Reporter ; Government Regulation ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Humans ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Microscopy, Electron ; Nucleocapsid Proteins/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; SARS-CoV-2/ultrastructure ; Spike Glycoprotein, Coronavirus/metabolism ; Viral Matrix Proteins/metabolism ; Virion/genetics ; Virion/metabolism ; Virion/ultrastructure ; Virus Assembly/physiology ; Virus Internalization ; Virus Release/physiology ; Red Fluorescent Protein

المؤلفون: Plescia CB, David EA, Patra D, Sengupta R, Amiar S, Su Y, Stahelin RV

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2020 Oct 01. Date of Electronic Publication: 2020 Oct 01.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Abeywickrama CS; Department of Chemistry, University of Akron, 44325, Akron, Ohio, USA., Wijesinghe KJ; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA., Plescia CB; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 47907, West Lafayette, Indiana, USA., Fisher LS; Department of Chemistry, University of Michigan, 48109, Ann Arbor, MI, USA., Goodson T 3rd; Department of Chemistry, University of Michigan, 48109, Ann Arbor, MI, USA., Stahelin RV; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 47907, West Lafayette, Indiana, USA., Pang Y; Department of Chemistry, University of Akron, 44325, Akron, Ohio, USA. yp5@uakron.edu.; Maurice Morton Institute of Polymer Science, University of Akron, 44325, Akron, Ohio, USA. yp5@uakron.edu.

المصدر: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology [Photochem Photobiol Sci] 2020 Sep 09; Vol. 19 (9), pp. 1152-1159.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: England NLM ID: 101124451 Publication Model: Print Cited Medium: Internet ISSN: 1474-9092 (Electronic) Linking ISSN: 1474905X NLM ISO Abbreviation: Photochem Photobiol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Photons*, Cell Nucleus/*chemistry , Fluorescent Dyes/*chemistry , Pyrenes/*chemistry, Animals ; COS Cells ; Cattle ; Cell Survival ; Cells, Cultured ; Chlorocebus aethiops ; DNA/chemistry ; Microscopy, Fluorescence ; Molecular Structure ; Pyridinium Compounds/chemistry

المؤلفون: Ravala SK; Departments of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.; The Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA., Hopkins JB; Biophysics Collaborative Access Team, Illinois Institute of Technology, Advanced Photon Source, Argonne National Laboratory, Lemont, Illinois, USA., Plescia CB; The Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA., Allgood SR; Departments of Biological Sciences, Purdue University, West Lafayette, Indiana, USA., Kane MA; College of Engineering, California State University, Long Beach, California, USA., Cash JN; Department of Biological Chemistry & Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA., Stahelin RV; The Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA., Tesmer JJG; Departments of Biological Sciences, Purdue University, West Lafayette, Indiana, USA jtesmer@purdue.edu.; The Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA.

المصدر: The Journal of biological chemistry [J Biol Chem] 2020 Sep 04; Vol. 295 (36), pp. 12635-12647. Date of Electronic Publication: 2020 Jul 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane*/chemistry , Cell Membrane*/genetics , Cell Membrane*/metabolism , Guanine Nucleotide Exchange Factors*/chemistry , Guanine Nucleotide Exchange Factors*/genetics , Guanine Nucleotide Exchange Factors*/metabolism, Cyclic AMP-Dependent Protein Kinases/chemistry ; Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Humans ; Phosphorylation ; Protein Domains

المؤلفون: Smulders L; Department of Biological Science, Center for Applied Biotechnology Studies, and Center for Computational and Applied Mathematics, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA 92834-6850, USA., Daniels AJ; Department of Biological Science, Center for Applied Biotechnology Studies, and Center for Computational and Applied Mathematics, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA 92834-6850, USA., Plescia CB; Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA., Berger D; Department of Biological Science, Center for Applied Biotechnology Studies, and Center for Computational and Applied Mathematics, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA 92834-6850, USA., Stahelin RV; Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA., Nikolaidis N; Department of Biological Science, Center for Applied Biotechnology Studies, and Center for Computational and Applied Mathematics, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA 92834-6850, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2020 Aug 20; Vol. 21 (17). Date of Electronic Publication: 2020 Aug 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: HSP70 Heat-Shock Proteins/*chemistry , HSP70 Heat-Shock Proteins/*metabolism , Liposomes/*metabolism , Phosphatidylserines/*metabolism, Adenosine Triphosphate/metabolism ; Amino Acid Substitution ; Animals ; Circular Dichroism ; HSP70 Heat-Shock Proteins/genetics ; Liposomes/chemistry ; Lysine/genetics ; Mice ; Molecular Chaperones/metabolism ; Mutation ; Phosphatidylcholines/metabolism ; Phosphatidylserines/chemistry ; Protein Binding ; Protein Refolding ; Protein Structure, Secondary ; Surface Plasmon Resonance