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المؤلفون: Song Y; Vaccine, Immunity and Cancer Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Loomans-Kropp H; Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA.; Now at Department of Internal Medicine, The Ohio State University, Columbus, OH, USA., Baugher RN; Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Somerville B; Vaccine, Immunity and Cancer Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Baxter SS; Vaccine, Immunity and Cancer Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Kerr TD; Vaccine, Immunity and Cancer Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Plona TM; Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Mellott SD; Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Young TB; Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Lawhorn HE; Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Wei L; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Hu Q; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Liu S; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Hutson A; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Pinto L; Vaccine, Immunity and Cancer Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Potter JD; Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Research Centre for Hauora and Health, Massey University, Wellington, New Zealand.; School of Public Health, University of Washington, Seattle, WA, USA., Sei S; Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA., Gelincik O; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Lipkin SM; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Gebert J; Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Kloor M; Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Shoemaker RH; Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA.

المصدر: Journal of the National Cancer Institute [J Natl Cancer Inst] 2024 Jun 07; Vol. 116 (6), pp. 957-965.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7503089 Publication Model: Print Cited Medium: Internet ISSN: 1460-2105 (Electronic) Linking ISSN: 00278874 NLM ISO Abbreviation: J Natl Cancer Inst Subsets: MEDLINE

مواضيع طبية MeSH: Frameshift Mutation* , Colorectal Neoplasms, Hereditary Nonpolyposis*/genetics , Colorectal Neoplasms, Hereditary Nonpolyposis*/diagnosis , Colorectal Neoplasms, Hereditary Nonpolyposis*/blood , Biomarkers, Tumor*/blood , Biomarkers, Tumor*/genetics , Microsatellite Instability*, Humans ; Male ; Female ; Middle Aged ; Adult ; Aged ; DNA Mismatch Repair/genetics ; High-Throughput Nucleotide Sequencing ; ROC Curve ; Case-Control Studies ; Sensitivity and Specificity

المؤلفون: Song Y; Frederick National Laboratory for Cancer Research, Vaccine, Immunity, and Cancer Directorate, Frederick, MD, United States., Kerr TD; Frederick National Laboratory for Cancer Research, Vaccine, Immunity, and Cancer Directorate, Frederick, MD, United States., Sanders C; Frederick National Laboratory for Cancer Research, Laboratory Animal Sciences Program, Frederick, MD, United States., Dai L; Frederick National Laboratory for Cancer Research, Vaccine, Immunity, and Cancer Directorate, Frederick, MD, United States., Baxter SS; Frederick National Laboratory for Cancer Research, Vaccine, Immunity, and Cancer Directorate, Frederick, MD, United States., Somerville B; Frederick National Laboratory for Cancer Research, Vaccine, Immunity, and Cancer Directorate, Frederick, MD, United States., Baugher RN; Frederick National Laboratory for Cancer Research, Clinical Laboratory Improvement Amendments (CLIA) Molecular Diagnostics Laboratory, Frederick, MD, United States., Mellott SD; Frederick National Laboratory for Cancer Research, Clinical Laboratory Improvement Amendments (CLIA) Molecular Diagnostics Laboratory, Frederick, MD, United States., Young TB; Frederick National Laboratory for Cancer Research, Clinical Laboratory Improvement Amendments (CLIA) Molecular Diagnostics Laboratory, Frederick, MD, United States., Lawhorn HE; Frederick National Laboratory for Cancer Research, Clinical Laboratory Improvement Amendments (CLIA) Molecular Diagnostics Laboratory, Frederick, MD, United States., Plona TM; Frederick National Laboratory for Cancer Research, Clinical Laboratory Improvement Amendments (CLIA) Molecular Diagnostics Laboratory, Frederick, MD, United States., Xu B; Frederick National Laboratory for Cancer Research, Genomics Laboratory, Frederick, MD, United States., Wei L; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States., Hu Q; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States., Liu S; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States., Hutson A; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States., Karim B; Molecular Histopathology Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, United States., Burkett S; Molecular Cytogenetics Core Facility, National Cancer Institute, Frederick, MD, United States., Difilippantonio S; Frederick National Laboratory for Cancer Research, Laboratory Animal Sciences Program, Frederick, MD, United States., Pinto L; Frederick National Laboratory for Cancer Research, Vaccine, Immunity, and Cancer Directorate, Frederick, MD, United States., Gebert J; Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany., Kloor M; Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany., Lipkin SM; Department of Medicine, Weill Cornell Medical College, Cornell University, New York, NY, United States., Sei S; Chemopreventive Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, United States., Shoemaker RH; Chemopreventive Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, United States.

المصدر: Frontiers in oncology [Front Oncol] 2023 Sep 08; Vol. 13, pp. 1223915. Date of Electronic Publication: 2023 Sep 08 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE

المؤلفون: Biswas K; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Couillard M; The Lady Davis Institute of the Jewish General Hospital, McGill University, Montreal, QC, Canada., Cavallone L; The Lady Davis Institute of the Jewish General Hospital, McGill University, Montreal, QC, Canada., Burkett S; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Stauffer S; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Martin BK; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.; Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA., Southon E; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.; Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA., Reid S; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Plona TM; CLIA Molecular Diagnostics Laboratory, Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Baugher RN; CLIA Molecular Diagnostics Laboratory, Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Mellott SD; CLIA Molecular Diagnostics Laboratory, Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Pike KM; CLIA Molecular Diagnostics Laboratory, Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Albaugh ME; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.; Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA., Maedler-Kron C; Department of Pathology, McGill University, Montreal, QC, Canada., Hamel N; Department of Oncology, McGill University, Montreal, QC, Canada.; Department of Human Genetics, McGill University, Montreal, QC, Canada., Tessarollo L; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Marcus V; Department of Pathology, McGill University, Montreal, QC, Canada., Foulkes WD; The Lady Davis Institute of the Jewish General Hospital, McGill University, Montreal, QC, Canada.; Department of Oncology, McGill University, Montreal, QC, Canada.; Department of Human Genetics, McGill University, Montreal, QC, Canada.; Department of Medical Genetics, Jewish General Hospital, McGill University, Montreal, QC, H3T 1E2, Canada.; Department of Medical Genetics and Cancer Research Program, Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, H4A 3JI, Canada., Sharan SK; Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA. sharans@mail.nih.gov.

المصدر: Cell death & disease [Cell Death Dis] 2021 Sep 06; Vol. 12 (9), pp. 838. Date of Electronic Publication: 2021 Sep 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Founder Effect*, DNA Mismatch Repair/*genetics , Mismatch Repair Endonuclease PMS2/*genetics , Mutation/*genetics , RNA Splicing/*genetics, Adenomatous Polyposis Coli Protein/genetics ; Animals ; Base Sequence ; Disease Models, Animal ; Exons/genetics ; Fertility/genetics ; Fibroblasts/metabolism ; Male ; Meiosis ; Mice, Inbred C57BL ; Microsatellite Instability ; Mismatch Repair Endonuclease PMS2/metabolism ; Morpholinos/pharmacology ; Polyps/pathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Spermatozoa/pathology ; Testis/pathology ; Mice

المؤلفون: Sissung TM; Clinical Pharmacology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Barbier RH; Molecular Pharmacology Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Price DK; Molecular Pharmacology Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Plona TM; CLIA Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD 21702, USA., Pike KM; CLIA Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD 21702, USA., Mellott SD; CLIA Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD 21702, USA., Baugher RN; CLIA Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD 21702, USA., Whiteley GR; CLIA Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD 21702, USA., Soppet DR; Genomics Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD 21702, USA., Venzon D; Biostatistics and Data Management, National Cancer Institute, National Institutes of Health, Rockville, MD 20850, USA., Berman A; Office of Research Nursing in the Office of the Clinical Director, National Cancer Institutes, National Institutes of Health, Bethesda, MD 20892, USA., Rajan A; Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Giaccone G; Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Meltzer P; Genetics Branch, National Cancer Institute, Bethesda, MD 20814, USA., Figg WD; Clinical Pharmacology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Molecular Pharmacology Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2020 Jan 30; Vol. 21 (3). Date of Electronic Publication: 2020 Jan 30.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Genetic*, Genotyping Techniques/*methods , Glucuronosyltransferase/*genetics, Alleles ; Genotype ; Humans ; Irinotecan ; Pharmacogenetics ; Polymerase Chain Reaction

المؤلفون: Sissung TM; Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, Rockville, MD, USA., McKeeby JW; Department of Clinical Research Informatics, NIH Clinical Center, Bethesda, MD, USA., Patel J; Pharmacy Department, NIH Clinical Center, Bethesda, MD, USA., Lertora JJ; Clinical Pharmacology Program (2006-2016), NIH Clinical Center, Bethesda, MD, USA., Kumar P; Clinical Pharmacokinetics Research Laboratory, NIH Clinical Center, Bethesda, MD, USA., Flegel WA; Department of Transfusion Medicine, NIH Clinical Center, Bethesda, MD, USA., Adams SD; Department of Transfusion Medicine, NIH Clinical Center, Bethesda, MD, USA., Eckes EJ; Medical Surgical Specialties Service, Clinical Center Nursing Department, NIH, Bethesda, MD, USA., Mickey F; Department of Clinical Research Informatics, NIH Clinical Center, Bethesda, MD, USA., Plona TM; CLIA Molecular Diagnostics Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Mellot SD; CLIA Molecular Diagnostics Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Baugher RN; CLIA Molecular Diagnostics Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Wu X; Genomics Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Soppet DR; Genomics Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Barcus ME; CLIA Molecular Diagnostics Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Datta V; CLIA Molecular Diagnostics Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA.; Molecular Characterization Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Pike KM; CLIA Molecular Diagnostics Laboratory, Cancer Research Technology Program, and Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., DiPatrizio G; Department of Clinical Research Informatics, NIH Clinical Center, Bethesda, MD, USA., Figg WD; Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, Rockville, MD, USA., Goldspiel BR; Pharmacy Department, NIH Clinical Center, Bethesda, MD, USA.

المصدر: Journal of clinical pharmacology [J Clin Pharmacol] 2017 Oct; Vol. 57 Suppl 10, pp. S67-S77.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Biomedical Research/*organization & administration , National Institutes of Health (U.S.)/*organization & administration , Pharmacogenetics/*methods, Decision Support Systems, Clinical ; Genotype ; Humans ; Medical Informatics ; Organizational Policy ; United States

المؤلفون: Bradford PT; Genetic Epidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Bethesda, Maryland 20892-4258, USA., Goldstein AM, Tamura D, Khan SG, Ueda T, Boyle J, Oh KS, Imoto K, Inui H, Moriwaki S, Emmert S, Pike KM, Raziuddin A, Plona TM, DiGiovanna JJ, Tucker MA, Kraemer KH

المصدر: Journal of medical genetics [J Med Genet] 2011 Mar; Vol. 48 (3), pp. 168-76. Date of Electronic Publication: 2010 Nov 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural

بيانات الدورية: Publisher: British Medical Association Country of Publication: England NLM ID: 2985087R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-6244 (Electronic) Linking ISSN: 00222593 NLM ISO Abbreviation: J Med Genet Subsets: MEDLINE

مواضيع طبية MeSH: DNA Repair*, Melanoma/*genetics , Neurodegenerative Diseases/*genetics , Skin Neoplasms/*genetics , Xeroderma Pigmentosum/*genetics, Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Humans ; Infant ; Male ; Melanoma/complications ; Middle Aged ; Neurodegenerative Diseases/complications ; Neurodegenerative Diseases/mortality ; Receptor, Melanocortin, Type 1/genetics ; Retrospective Studies ; Skin Neoplasms/complications ; Skin Neoplasms/mortality ; Xeroderma Pigmentosum/complications ; Young Adult