نتائج البحث - "Po-Shun Lee"

1

دورية أكاديمية

Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue

المصدر: EMBO Molecular Medicine, Vol 9, Iss 9, Pp 1224-1243 (2017)

مصطلحات موضوعية: amplifier, c.3700 A>G, CFTR, CRISPR/Cas9, cystic fibrosis, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/63e4048262714fd991511c4196c2fb6d

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2

دورية أكاديمية

Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis.

المؤلفون: Chenggang Li, Erik Zhang, Yang Sun, Po-Shun Lee, Yongzhong Zhan, Yanan Guo, Juan C Osorio, Ivan O Rosas, Kai-Feng Xu, David J Kwiatkowski, Jane J Yu

المصدر: PLoS ONE, Vol 9, Iss 10, p e104809 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4210122?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3e4c5f336bae4f4c9e51c1d13b9fd0e6

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3

دورية أكاديمية

mTORC1-S6K activation by endotoxin contributes to cytokine up-regulation and early lethality in animals.

المؤلفون: Po-Shun Lee, Anna S K Wilhelmson, Anton P Hubner, Samuel B Reynolds, Dana A Gallacchi, Terry T Chiou, David J Kwiatkowski

المصدر: PLoS ONE, Vol 5, Iss 12, p e14399 (2010)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3006197?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/a9c7fa2bab1b4ab7816a3510db84f54a

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4

دورية أكاديمية

Plasma gelsolin depletion and circulating actin in sepsis: a pilot study.

المؤلفون: Po-Shun Lee, Sanjay R Patel, David C Christiani, Ednan Bajwa, Thomas P Stossel, Aaron B Waxman

المصدر: PLoS ONE, Vol 3, Iss 11, p e3712 (2008)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2577888?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/10e33f316a844029be1611be06b00d12

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5

The Effect of Concomitant Sirolimus and Propofol Therapy on Triglyceride Concentrations in Critically Ill Patients

المؤلفون: Megan A. Rocchio, Kevin E. Anger, Paul M. Szumita, Kevin M Dube, Po-Shun Lee

المصدر: American Journal of Therapeutics. 26:e103-e109

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cbf4407700aa0f14bfb9ba1b58849a
https://doi.org/10.1097/mjt.0000000000000461

6

A Novel Allogeneic Cell Therapy That Targets Pathogenic Autoantibodies for the Treatment of Immune Thrombocytopenia

المؤلفون: Sunita Patel-Hett, Douglas Lazarus, Christian G. Peters, Amanda Leung, Sayaka Masuko, Dora E Kohnke, Lindsay Tomczak, Angelique Meredith, Brad Dykstra, Marcus Lehmann, Silvia Giannini, Dean Falb, Ryan Carpenter, Po-Shun Lee, Sophia Pete, Ashley J Russo

المصدر: Blood. 138:1001-1001

مصطلحات موضوعية: Allogeneic cell, business.industry, Immunology, Autoantibody, Medicine, Cell Biology, Hematology, business, Biochemistry, Immune thrombocytopenia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6b7f4593ede3ca470c693bd8ec511104
https://doi.org/10.1182/blood-2021-150823

7

Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA

المؤلفون: Daniel Finley, Danijela Dukovski, J.P. Miller, Cecilia M. Bastos, Jeffery W. Kelly, Richard I. Morimoto, Benito Munoz, Randall W. King, F. Ulrich Hartl, Po Shun Lee, Adriana Villella, Marija Zecevic

المصدر: Journal of cystic fibrosis

مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, congenital, hereditary, and neonatal diseases and abnormalities, Cystic Fibrosis, Translational efficiency, Cystic Fibrosis Transmembrane Conductance Regulator, 03 medical and health sciences, 0302 clinical medicine, Polysome, Humans, Medicine, RNA, Messenger, Chloride Channel Agonists, Messenger RNA, biology, business.industry, RNA-Binding Proteins, Translation (biology), MRNA stabilization, Potentiator, respiratory system, Cystic fibrosis transmembrane conductance regulator, digestive system diseases, Cell biology, respiratory tract diseases, DNA-Binding Proteins, 030104 developmental biology, Gene Expression Regulation, 030228 respiratory system, Pediatrics, Perinatology and Child Health, biology.protein, Translational elongation, business

وصف الملف: application/pdf; application/zip

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8d08db66648517be6e46ada5b6addd
https://hdl.handle.net/21.11116/0000-0007-4DBE-E21.11116/0000-0007-4DC1-921.11116/0000-0007-4DC0-A

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Use of a High-Throughput Phenotypic Screening Strategy to Identify Amplifiers, a Novel Pharmacological Class of Small Molecules That Exhibit Functional Synergy with Potentiators and Correctors

المؤلفون: Matthew Cullen, Cecilia M. Bastos, Lawrence Drew, Danijela Dukovski, Benito Munoz, Kenneth A. Giuliano, Shinichiro Wachi, Po-Shun Lee, Sheila Hauck, Olivia Green, Bradley D. Tait, John P. Miller

المصدر: Slas Discovery

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Cystic Fibrosis, Genotype, High-throughput screening, Phenotypic screening, Cystic Fibrosis Transmembrane Conductance Regulator, Endoplasmic Reticulum, medicine.disease_cause, high-throughput screening, Biochemistry, Cystic fibrosis, Cell Line, Analytical Chemistry, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Humans, phenotypic assays, Original Research, CFTR modulator, Genetics, Mutation, biology, Genetic disorder, PTI-CH, respiratory system, Potentiator, medicine.disease, Phenotype, digestive system diseases, Cystic fibrosis transmembrane conductance regulator, High-Throughput Screening Assays, respiratory tract diseases, Cell biology, 030104 developmental biology, 030228 respiratory system, biology.protein, Molecular Medicine, amplifiers, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0ad75dc6470779f40014d6f7a23b0b
https://doi.org/10.1177/2472555217729790

9

Orkambi® and amplifier co‐therapy improves function from a rare CFTR mutation in gene‐edited cells and patient tissue

المصدر: EMBO Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Combination therapy, Cystic Fibrosis, In silico, Respiratory System, Aminopyridines, Cystic Fibrosis Transmembrane Conductance Regulator, Biology, Quinolones, Bioinformatics, medicine.disease_cause, Aminophenols, Cystic fibrosis, Ivacaftor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, CRISPR, Humans, Point Mutation, Benzodioxoles, CFTR, ΔF508, CRISPR/Cas9, Research Articles, c.3700 A>G, Gene Editing, Mutation, Lumacaftor, Genetic Therapy, medicine.disease, Combined Modality Therapy, 3. Good health, Drug Combinations, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, amplifier, Cancer research, Molecular Medicine, Genetics, Gene Therapy & Genetic Disease, medicine.drug, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aaadb2a10accd16a9627ce93c3d4764
http://europepmc.org/articles/PMC5582412

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10

Gelsolin and Progression of Aortic Arch Calcification in Chronic Hemodialysis Patients

المؤلفون: Po-Shun Lee, Hwee-Yeong Ng, Shang-Chih Liao, Wen-Chin Lee, Yueh-Ting Lee, Chien-Te Lee, Terry Ting-Yu Chiou, Yu-Yin Kao

المصدر: International Journal of Medical Sciences

مصطلحات موضوعية: Adult, medicine.medical_specialty, Pathology, Waist, gelsolin, medicine.medical_treatment, 030232 urology & nephrology, Serum albumin, Aorta, Thoracic, macromolecular substances, 030204 cardiovascular system & hematology, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Renal Dialysis, Internal medicine, hemodialysis, Medicine, Humans, Vascular Calcification, Aged, biology, business.industry, Vascular disease, General Medicine, Odds ratio, biochemical phenomena, metabolism, and nutrition, Middle Aged, medicine.disease, Confidence interval, Aortic arch calcification, biology.protein, Radiography, Thoracic, Hemodialysis, business, Gelsolin, Biomarkers, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84984ec1b21fd97b1794d4d4bfa83404
http://europepmc.org/articles/PMC4764774

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