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المؤلفون: Zhong X; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Li Q; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Polacco BJ; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Patil T; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Marley A; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA, 94158, USA., Foussard H; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Khare P; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Vartak R; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Xu J; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., DiBerto JF; Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Roth BL; Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Eckhardt M; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., von Zastrow M; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA, 94158, USA., Krogan NJ; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA., Hüttenhain R; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, 94158, USA. ruthh@stanford.edu.; J. David Gladstone Institutes, San Francisco, CA, 94158, USA. ruthh@stanford.edu.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 94158, USA. ruthh@stanford.edu.; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, 94305, USA. ruthh@stanford.edu.

المصدر: Molecular systems biology [Mol Syst Biol] 2024 Jul 01. Date of Electronic Publication: 2024 Jul 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE

المؤلفون: Jang GM; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA; J. David Gladstone Institutes, Gladstone Institute for Data Science and Biotechnology, San Francisco, California, USA., Annan Sudarsan AK; College of Medicine, Biochemistry, Microbiology & Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Shayeganmehr A; College of Medicine, Biochemistry, Microbiology & Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Prando Munhoz E; College of Medicine, Biochemistry, Microbiology & Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Lao R; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA; J. David Gladstone Institutes, Gladstone Institute for Data Science and Biotechnology, San Francisco, California, USA., Gaba A; College of Medicine, Biochemistry, Microbiology & Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Granadillo Rodríguez M; College of Medicine, Biochemistry, Microbiology & Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Love RP; College of Medicine, Biochemistry, Microbiology & Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Polacco BJ; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA., Zhou Y; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA; J. David Gladstone Institutes, Gladstone Institute for Data Science and Biotechnology, San Francisco, California, USA., Krogan NJ; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA; J. David Gladstone Institutes, Gladstone Institute for Data Science and Biotechnology, San Francisco, California, USA., Kaake RM; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, USA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, California, USA; J. David Gladstone Institutes, Gladstone Institute for Data Science and Biotechnology, San Francisco, California, USA. Electronic address: robyn.kaake@gladstone.ucsf.edu., Chelico L; College of Medicine, Biochemistry, Microbiology & Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. Electronic address: linda.chelico@usask.ca.

المصدر: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2024 May; Vol. 23 (5), pp. 100755. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE

مواضيع طبية MeSH: Cytidine Deaminase*/metabolism , Cytidine Deaminase*/genetics , Protein Interaction Maps*, Humans ; Deamination ; APOBEC Deaminases/metabolism ; Aminohydrolases/metabolism ; Aminohydrolases/genetics ; HEK293 Cells ; Cytosine Deaminase/metabolism ; APOBEC-3G Deaminase/metabolism ; APOBEC-3G Deaminase/genetics ; Spliceosomes/metabolism ; Protein Binding ; Mass Spectrometry ; RNA/metabolism ; Minor Histocompatibility Antigens/metabolism ; Minor Histocompatibility Antigens/genetics

المؤلفون: Polacco BJ; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; J. David Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA., Lobingier BT; Department of Chemical Physiology and Biochemistry, Oregon Health and Sciences University, Portland, OR, USA., Blythe EE; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA, USA., Abreu N; Department of Biochemistry, Weill Cornell Medicine, New York, NY, USA., Khare P; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; J. David Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA., Howard MK; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.; TETRAD Graduate Program, University of California San Francisco, San Francisco, CA, USA., Gonzalez-Hernandez AJ; Department of Biochemistry, Weill Cornell Medicine, New York, NY, USA., Xu J; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; J. David Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA., Li Q; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; J. David Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA., Novy B; Department of Chemical Physiology and Biochemistry, Oregon Health and Sciences University, Portland, OR, USA., Naing ZZC; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; J. David Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA., Shoichet BK; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA., Coyote-Maestas W; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Levitz J; Department of Biochemistry, Weill Cornell Medicine, New York, NY, USA., Krogan NJ; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA.; J. David Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA., Von Zastrow M; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA. mark.vonzastrow@ucsf.edu.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA. mark.vonzastrow@ucsf.edu.; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA, USA. mark.vonzastrow@ucsf.edu., Hüttenhain R; Quantitative Biosciences Institute (QBI), University of California, San Francisco, CA, USA. ruthh@stanford.edu.; J. David Gladstone Institutes, San Francisco, CA, USA. ruthh@stanford.edu.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA. ruthh@stanford.edu.; Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA. ruthh@stanford.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2024 Mar 25. Date of Electronic Publication: 2024 Mar 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

المؤلفون: Wang B, Vartak R, Zaltsman Y, Naing ZZC, Hennick KM, Polacco BJ, Bashir A, Eckhardt M, Bouhaddou M, Xu J, Sun N, Lasser MC, Zhou Y, McKetney J, Guiley KZ, Chan U, Kaye JA, Chadha N, Cakir M, Gordon M, Khare P, Drake S, Drury V, Burke DF, Gonzalez S, Alkhairy S, Thomas R, Lam S, Morris M, Bader E, Seyler M, Baum T, Krasnoff R, Wang S, Pham P, Arbalaez J, Pratt D, Chag S, Mahmood N, Rolland T, Bourgeron T, Finkbeiner S, Swaney DL, Bandyopadhay S, Ideker T, Beltrao P, Willsey HR, Obernier K, Nowakowski TJ, Hüttenhain R, State MW, Willsey AJ, Krogan NJ

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 08. Date of Electronic Publication: 2024 Feb 08.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Chen Z; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA. Electronic address: zhen.chen@ucsf.edu., Shiozaki M; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Haas KM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; J. David Gladstone Institutes, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA., Skinner WM; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Zhao S; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Guo C; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Polacco BJ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA., Yu Z; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Krogan NJ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; J. David Gladstone Institutes, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA., Lishko PV; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA., Kaake RM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; J. David Gladstone Institutes, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA., Vale RD; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. Electronic address: valer@janelia.hhmi.org., Agard DA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA. Electronic address: david@agard.ucsf.edu.

المصدر: Cell [Cell] 2023 Nov 09; Vol. 186 (23), pp. 5041-5053.e19. Date of Electronic Publication: 2023 Oct 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Spermatozoa*/chemistry , Proteome*/analysis, Animals ; Male ; Mice ; Axoneme/chemistry ; Cryoelectron Microscopy/methods ; Flagella/metabolism ; Microtubules/metabolism ; Semen

المؤلفون: Bouhaddou M; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California, Los Angeles, Los Angeles, CA, USA; Institute for Quantitative and Computational Biosciences (QCBio), University of California, Los Angeles, Los Angeles, CA, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA., Reuschl AK; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Division of Infection and Immunity, University College London, London, UK., Polacco BJ; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Thorne LG; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Division of Infection and Immunity, University College London, London, UK., Ummadi MR; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Ye C; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Texas Biomedical Research Institute, San Antonio, TX, USA., Rosales R; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Pelin A; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Batra J; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Jang GM; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Xu J; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Moen JM; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Richards AL; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Zhou Y; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Harjai B; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Stevenson E; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Rojc A; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Ragazzini R; Division of Infection and Immunity, University College London, London, UK; Epithelial Stem Cell Biology and Regenerative Medicine Laboratory, The Francis Crick Institute, London, UK., Whelan MVX; Division of Infection and Immunity, University College London, London, UK., Furnon W; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., De Lorenzo G; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Cowton V; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Syed AM; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Ciling A; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Deutsch N; School of Computer Science, Tel Aviv University, Tel Aviv, Israel., Pirak D; School of Electrical Engineering, Tel Aviv University, Tel Aviv, Israel., Dowgier G; COVID Surveillance Unit, The Francis Crick Institute, London, UK., Mesner D; Division of Infection and Immunity, University College London, London, UK., Turner JL; Division of Infection and Immunity, University College London, London, UK., McGovern BL; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rodriguez ML; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Leiva-Rebollo R; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dunham AS; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Saffron Walden, UK., Zhong X; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Eckhardt M; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Fossati A; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Liotta NF; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA., Kehrer T; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cupic A; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rutkowska M; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mena I; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Aslam S; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hoffert A; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Foussard H; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Olwal CO; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra, Ghana; Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana., Huang W; Huffington Center for Cell-based Research in Parkinson's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Zwaka T; Huffington Center for Cell-based Research in Parkinson's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Pham J; Synthego Corporation, Redwood City, CA, USA., Lyons M; Synthego Corporation, Redwood City, CA, USA., Donohue L; Synthego Corporation, Redwood City, CA, USA., Griffin A; Synthego Corporation, Redwood City, CA, USA., Nugent R; Synthego Corporation, Redwood City, CA, USA., Holden K; Synthego Corporation, Redwood City, CA, USA., Deans R; Synthego Corporation, Redwood City, CA, USA., Aviles P; Pharma Mar S.A, Madrid, Spain., Lopez-Martin JA; Pharma Mar S.A, Madrid, Spain., Jimeno JM; Pharma Mar S.A, Madrid, Spain., Obernier K; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Fabius JM; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Soucheray M; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Hüttenhain R; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Jungreis I; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kellis M; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Echeverria I; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA., Verba K; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA., Bonfanti P; Division of Infection and Immunity, University College London, London, UK; Epithelial Stem Cell Biology and Regenerative Medicine Laboratory, The Francis Crick Institute, London, UK., Beltrao P; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Cambridge, UK; Institute of Molecular Systems Biology, Department of Biology, ETH Zürich, Zurich, Switzerland., Sharan R; School of Computer Science, Tel Aviv University, Tel Aviv, Israel., Doudna JA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA., Martinez-Sobrido L; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Texas Biomedical Research Institute, San Antonio, TX, USA., Patel AH; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Palmarini M; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Miorin L; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., White K; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Swaney DL; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA., Garcia-Sastre A; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: adolfo.garcia-sastre@mssm.edu., Jolly C; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Division of Infection and Immunity, University College London, London, UK. Electronic address: c.jolly@ucl.ac.uk., Zuliani-Alvarez L; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA. Electronic address: lzulianialvarez@gmail.com., Towers GJ; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Division of Infection and Immunity, University College London, London, UK. Electronic address: g.towers@ucl.ac.uk., Krogan NJ; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA, USA; QBI Coronavirus Research Group (QCRG), University of California, San Francisco, San Francisco, CA, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Gladstone Institute of Data Science and Biotechnology, J. David Gladstone Institutes, San Francisco, CA, USA. Electronic address: nevan.krogan@ucsf.edu.

المصدر: Cell [Cell] 2023 Oct 12; Vol. 186 (21), pp. 4597-4614.e26. Date of Electronic Publication: 2023 Sep 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/virology , SARS-CoV-2*/genetics, Humans ; Immunity, Innate/genetics ; Pandemics

SCR Organism: SARS-CoV-2 variants

المؤلفون: Kehrer T; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Cupic A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Ye C; Texas Biomedical Research Institute, San Antonio, TX 78227, USA., Yildiz S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Bouhaddou M; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California, Los Angeles, Los Angeles, CA 90024, USA; Institute for Quantitative and Computational Biosciences (OCBio), University of California, Los Angeles, Los Angeles, CA 90024, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90024, USA., Crossland NA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02215, USA; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA., Barrall EA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Cohen P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Tseng A; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02215, USA; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA., Çağatay T; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Rathnasinghe R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Flores D; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Jangra S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Alam F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Mena I; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Aslam S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Saqi A; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA., Rutkowska M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Ummadi MR; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., Pisanelli G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy., Richardson RB; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Veit EC; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Fabius JM; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Soucheray M; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., Polacco BJ; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., Ak B; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Marin A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Evans MJ; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Swaney DL; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., Gonzalez-Reiche AS; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Sordillo EM; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., van Bakel H; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Simon V; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Center for Vaccine Research and Pandemic Preparedness (C-VARPP), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Zuliani-Alvarez L; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., Fontoura BMA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Rosenberg BR; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Krogan NJ; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA., Martinez-Sobrido L; Texas Biomedical Research Institute, San Antonio, TX 78227, USA., García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: adolfo.garcia-sastre@mssm.edu., Miorin L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: lisa.miorin@mssm.edu.

المصدر: Cell host & microbe [Cell Host Microbe] 2023 Oct 11; Vol. 31 (10), pp. 1668-1684.e12. Date of Electronic Publication: 2023 Sep 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/virology , SARS-CoV-2*/genetics , Viral Proteins*/genetics , Viral Proteins*/metabolism, Humans ; Immunity, Innate ; Interferons/genetics ; Interferons/metabolism

المؤلفون: Haas KM; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., McGregor MJ; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Bouhaddou M; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Polacco BJ; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Kim EY; Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Nguyen TT; J. David Gladstone Institutes, San Francisco, CA, 94158, USA., Newton BW; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA., Urbanowski M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Kim H; Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Williams MAP; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Rezelj VV; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA.; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France., Hardy A; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France., Fossati A; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Stevenson EJ; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Sukerman E; Division of Infectious Diseases, Oregon Health & Science University, Portland, OR, 97239, USA., Kim T; Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Penugonda S; Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Moreno E; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Infectious Diseases, Hospital Universitario Ramón y Cajal and IRYCIS, Madrid, Spain.; Centro de Investigación en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain., Braberg H; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Zhou Y; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Metreveli G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Harjai B; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Tummino TA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA.; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA.; Graduate Program in Pharmaceutical Sciences and Pharmacogenomics, University of California San Francisco, San Francisco, CA, 94158, USA., Melnyk JE; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Soucheray M; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Batra J; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA., Pache L; Infectious and Inflammatory Disease Center, Immunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA., Martin-Sancho L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, 92037, USA.; Department of Infectious Disease, Imperial College London, London, SW7 2BX, UK., Carlson-Stevermer J; Synthego Corporation, Redwood City, CA, 94063, USA.; Serotiny Inc., South San Francisco, CA, 94080, USA., Jureka AS; Molecular Virology and Vaccine Team, Immunology and Pathogenesis Branch, Influenza Division, National Center for Immunization & Respiratory Diseases, Centers for Disease Control & Prevention, Atlanta, GA, 30333, USA.; General Dynamics Information Technology, Federal Civilian Division, Atlanta, GA, 30329, USA., Basler CF; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Shokat KM; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, 20815, USA., Shoichet BK; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA.; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, 94158, USA., Shriver LP; Department of Chemistry, Washington University in St. Louis, St. Louis, MO, 63105, USA.; Center for Metabolomics and Isotope Tracing, Washington University in St. Louis, St. Louis, MO, 63105, USA., Johnson JR; J. David Gladstone Institutes, San Francisco, CA, 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, 94158, USA.; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, 94158, USA.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Shaw ML; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Medical Biosciences, University of the Western Cape, Bellville, 7535, Western Cape, South Africa., Chanda SK; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, 92037, USA., Roden DM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Carter TC; Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield, WI, 54449, USA., Kottyan LC; Center of Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Chisholm RL; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Pacheco JA; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Smith ME; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Schrodi SJ; Laboratory of Genetics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI, 53706, USA., Albrecht RA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Vignuzzi M; Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG), San Francisco, CA, 94158, USA.; Institut Pasteur, Viral Populations and Pathogenesis Unit, CNRS UMR 3569, Paris, France., Zuliani-Alvarez L; J. 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المصدر: Nature communications [Nat Commun] 2023 Sep 27; Vol. 14 (1), pp. 6030. Date of Electronic Publication: 2023 Sep 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Influenza A virus*/genetics , Influenza, Human*/genetics , Influenza A Virus, H5N1 Subtype*/genetics , COVID-19*, Humans ; Influenza A Virus, H3N2 Subtype/metabolism ; Proteomics ; Virus Replication/genetics ; SARS-CoV-2 ; Antiviral Agents/metabolism ; Host-Pathogen Interactions/genetics