المؤلفون: Giovanni Bocci, Noel Southall, Dusica Vidovic, Cristian Bologa, Lars Juhl Jensen, Stephan C. Schürer, Tudor I. Oprea, Jayme Holmes, Vishal B. Siramshetty, Amar Koleti, Poorva Dharkar, Dac-Trung Nguyen, Anna Waller, Jeremy J. Yang, Timothy Sheils, Keith J. Kelleher, Anton Simeonov, Stephen L. Mathias, Ewy Mathé

المصدر: Sheils, T K, Mathias, S L, Kelleher, K J, Siramshetty, V B, Nguyen, D T, Bologa, C G, Jensen, L J, Vidović, D, Koleti, A, Schürer, S C, Waller, A, Yang, J J, Holmes, J, Bocci, G, Southall, N, Dharkar, P, Mathé, E, Simeonov, A & Oprea, T I 2021, ' TCRD and Pharos 2021 : mining the human proteome for disease biology ', Nucleic Acids Research, vol. 49, no. D1, pp. D1334-D1346 . https://doi.org/10.1093/nar/gkaa993
Nucleic Acids Research

مصطلحات موضوعية: Proteomics, Databases, Factual, Proteome, AcademicSubjects/SCI00010, Druggability, Disease, Biology, Antiviral Agents, Data type, Genome, Machine Learning, Small Molecule Libraries, World Wide Web, Mice, 03 medical and health sciences, 0302 clinical medicine, Resource (project management), Protein Interaction Mapping, Genetics, Human proteome project, Database Issue, Animals, Data Mining, Humans, Molecular Targeted Therapy, 030304 developmental biology, Mice, Knockout, Biological Products, Internet, 0303 health sciences, Genome, Human, Neurodegenerative Diseases, Virus Diseases, Host-Pathogen Interactions, Anticonvulsants, User interface, Software, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b704a90589085c564c27e01092a99c
https://curis.ku.dk/ws/files/256214286/gkaa993_1.pdf

المؤلفون: Alexander Wlodawer, Mi Li, Poorva Dharkar, Alfred L. Goldberg, Olga Kandror, Tatos Akopian, Michael R. Maurizi

المصدر: Journal of Biological Chemistry. 291:7465-7476

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, medicine.medical_treatment, ATPase, 030106 microbiology, Allosteric regulation, Plasma protein binding, Biology, Protein degradation, Biochemistry, Protein Structure, Secondary, 03 medical and health sciences, chemistry.chemical_compound, Allosteric Regulation, Bacterial Proteins, Multienzyme Complexes, medicine, Binding site, Protein Structure, Quaternary, Molecular Biology, Binding Sites, Protease, Dipeptide, Serine Endopeptidases, Dipeptides, Mycobacterium tuberculosis, Cell Biology, 030104 developmental biology, chemistry, Enzymology, biology.protein, Oxyanion hole, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccdbb63268dd5f8e566459e54d41ac81
https://doi.org/10.1074/jbc.m115.700344

المؤلفون: Chi-Hon Lee, Yan Li, Mihaela Serpe, Mark L. Mayer, Poorva Dharkar, Tae Hee Han

المصدر: Neuron. 92(5)

مصطلحات موضوعية: 0301 basic medicine, Agonist, Central Nervous System, N-Methylaspartate, medicine.drug_class, Kainate receptor, AMPA receptor, Biology, Ligands, Article, 03 medical and health sciences, chemistry.chemical_compound, Receptors, Kainic Acid, medicine, Enzyme-linked receptor, Excitatory Amino Acid Agonists, Animals, Humans, Quisqualic acid, Receptors, AMPA, Excitatory Amino Acid Agonist, Receptor, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, Crystallography, General Neuroscience, Quisqualic Acid, Cell biology, 030104 developmental biology, Drosophila melanogaster, HEK293 Cells, Biochemistry, chemistry, nervous system, Receptors, Glutamate, NMDA receptor, Calcium Channels, Excitatory Amino Acid Antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1210b3de262a9a1ec1a00bf8598d72
https://pubmed.ncbi.nlm.nih.gov/27889096

المؤلفون: Mihaela Serpe, Mark L. Mayer, Poorva Dharkar, Tae Hee Han

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 112(19)

مصطلحات موضوعية: animal structures, DNA, Complementary, Protein subunit, Molecular Sequence Data, Xenopus, Neuromuscular Junction, Crystallography, X-Ray, Ligands, Neuromuscular junction, Permeability, Synapse, Xenopus laevis, medicine, Animals, Drosophila Proteins, Amino Acid Sequence, Receptor, Ions, Multidisciplinary, Microscopy, Confocal, biology, Sequence Homology, Amino Acid, fungi, Cell Membrane, Glutamate receptor, Membrane Proteins, Biological Sciences, biology.organism_classification, Cell biology, Protein Structure, Tertiary, medicine.anatomical_structure, Drosophila melanogaster, Phenotype, Receptors, Glutamate, Mutation, Synapses, Oocytes, Calcium, Drosophila Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fdd524be7bdd0ad15d14406e536a2ad
https://pubmed.ncbi.nlm.nih.gov/25918369