المؤلفون: Jinrong Min, Matthew R. Marunde, Dmitri Kireev, Jack Greenblatt, Ferreira de Freitas R, Tigran M. Abramyan, Cheryl H. Arrowsmith, Peter Brown, Magda Szewczyk, Irene Chau, A. Dong, Kazemzadeh S, Dalia Barsyte-Lovejoy, Ronan P Hanley, Mengqi Zhou, Y. Liu, Michael-Christopher Keogh, Lindsey I. James, Edyta Marcon, Matthieu Schapira, David Dilworth, Ming Lei, Popova Ik, Albina Bolotokova, Marcus A. Cheek, Masoud Vedadi, Elisa Gibson, Suzanne Ackloo, Su Qin, Matthew J. Meiners, Nathan W. Hall, Abdellah Allali-Hassani, Naimee Mehta, Fengling Li

مصطلحات موضوعية: Gene isoform, Mutation, Methyltransferase, biology, Nucleolus, Chemistry, Methylation, medicine.disease_cause, Subcellular localization, Cell biology, Chromatin, Histone, medicine, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9e4c6ef23b32f1b09d83b9d0588c0ec9
https://doi.org/10.1101/2021.03.05.433782

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المؤلفون: Gretarsson KH; Department of Genetics and Development and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Abini-Agbomson S; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA., Gloor SL; EpiCypher Inc., Durham, NC 27709, USA., Weinberg DN; Department of Medicine, Weill Cornell Medical College, New York, NY 10065, USA., McCuiston JL; EpiCypher Inc., Durham, NC 27709, USA., Kumary VUS; EpiCypher Inc., Durham, NC 27709, USA., Hickman AR; EpiCypher Inc., Durham, NC 27709, USA., Sahu V; Department of Genetics and Development and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Lee R; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA., Xu X; Department of Genetics and Development and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Lipieta N; Department of Genetics and Development and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA., Flashner S; Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, New York, NY 10032, USA., Adeleke OA; EpiCypher Inc., Durham, NC 27709, USA., Popova IK; EpiCypher Inc., Durham, NC 27709, USA., Taylor HF; EpiCypher Inc., Durham, NC 27709, USA., Noll K; EpiCypher Inc., Durham, NC 27709, USA., Windham CL; EpiCypher Inc., Durham, NC 27709, USA., Maryanski DN; EpiCypher Inc., Durham, NC 27709, USA., Venters BJ; EpiCypher Inc., Durham, NC 27709, USA., Nakagawa H; Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, New York, NY 10032, USA., Keogh MC; EpiCypher Inc., Durham, NC 27709, USA., Armache KJ; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA., Lu C; Department of Genetics and Development and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA.

المصدر: Science advances [Sci Adv] 2024 Aug 30; Vol. 10 (35), pp. eadp0975. Date of Electronic Publication: 2024 Aug 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methylation* , DNA Methyltransferase 3A* , Nucleosomes*/metabolism , Histones*/metabolism , DNA (Cytosine-5-)-Methyltransferases*/metabolism , DNA (Cytosine-5-)-Methyltransferases*/genetics , Ubiquitination* , CpG Islands* , Protein Binding* , Neoplasms*/genetics , Neoplasms*/metabolism , Neoplasms*/pathology, Humans ; Polycomb-Group Proteins/metabolism ; Polycomb-Group Proteins/genetics ; Promoter Regions, Genetic ; Cryoelectron Microscopy ; Cell Line, Tumor

المؤلفون: Marunde MR; EpiCypher, Durham, United States., Fuchs HA; Department of Biochemistry, University of Iowa Carver College of Medicine, Aurora, United States.; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, United States., Burg JM; EpiCypher, Durham, United States., Popova IK; EpiCypher, Durham, United States., Vaidya A; EpiCypher, Durham, United States., Hall NW; EpiCypher, Durham, United States., Weinzapfel EN; EpiCypher, Durham, United States., Meiners MJ; EpiCypher, Durham, United States., Watson R; EpiCypher, Durham, United States., Gillespie ZB; EpiCypher, Durham, United States., Taylor HF; EpiCypher, Durham, United States., Mukhsinova L; EpiCypher, Durham, United States., Onuoha UC; EpiCypher, Durham, United States., Howard SA; EpiCypher, Durham, United States., Novitzky K; EpiCypher, Durham, United States., McAnarney ET; EpiCypher, Durham, United States., Krajewski K; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, United States., Cowles MW; EpiCypher, Durham, United States., Cheek MA; EpiCypher, Durham, United States., Sun ZW; EpiCypher, Durham, United States., Venters BJ; EpiCypher, Durham, United States., Keogh MC; EpiCypher, Durham, United States., Musselman CA; Department of Biochemistry, University of Iowa Carver College of Medicine, Aurora, United States.; Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, United States.

المصدر: ELife [Elife] 2024 Feb 06; Vol. 13. Date of Electronic Publication: 2024 Feb 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Nucleosomes* , Histones*/metabolism, Histone Code ; Chromatin ; Protein Processing, Post-Translational ; Peptides/metabolism

المؤلفون: Jain K; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill of Medicine, Chapel Hill, United States.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, United States., Marunde MR; EpiCypher, Inc, Durham, United States., Burg JM; EpiCypher, Inc, Durham, United States., Gloor SL; EpiCypher, Inc, Durham, United States., Joseph FM; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States., Poncha KF; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States., Gillespie ZB; EpiCypher, Inc, Durham, United States., Rodriguez KL; EpiCypher, Inc, Durham, United States., Popova IK; EpiCypher, Inc, Durham, United States., Hall NW; EpiCypher, Inc, Durham, United States., Vaidya A; EpiCypher, Inc, Durham, United States., Howard SA; EpiCypher, Inc, Durham, United States., Taylor HF; EpiCypher, Inc, Durham, United States., Mukhsinova L; EpiCypher, Inc, Durham, United States., Onuoha UC; EpiCypher, Inc, Durham, United States., Patteson EF; EpiCypher, Inc, Durham, United States., Cooke SW; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill of Medicine, Chapel Hill, United States., Taylor BC; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States., Weinzapfel EN; EpiCypher, Inc, Durham, United States., Cheek MA; EpiCypher, Inc, Durham, United States., Meiners MJ; EpiCypher, Inc, Durham, United States., Fox GC; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, United States., Namitz KEW; Pennsylvania State University, State College, United States., Cowles MW; EpiCypher, Inc, Durham, United States., Krajewski K; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill of Medicine, Chapel Hill, United States., Sun ZW; EpiCypher, Inc, Durham, United States., Cosgrove MS; Department of Biochemistry and Molecular Biology, Upstate Medical University, Syracuse, United States., Young NL; Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States., Keogh MC; EpiCypher, Inc, Durham, United States., Strahl BD; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill of Medicine, Chapel Hill, United States.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, United States.; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, United States.

المصدر: ELife [Elife] 2023 May 19; Vol. 12. Date of Electronic Publication: 2023 May 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin* , Histones*/metabolism, Nucleosomes ; Methylation ; Acetylation

المؤلفون: Zukin SA; College of Chemistry, University of California, Berkeley, Berkeley, United States., Marunde MR; EpiCypher, Inc, Research Triangle Park, Durham, United States., Popova IK; EpiCypher, Inc, Research Triangle Park, Durham, United States., Soczek KM; California Institute for Quantitative Biology, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cellular Biology, University of California, Berkeley, United States.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, United States., Nogales E; California Institute for Quantitative Biology, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cellular Biology, University of California, Berkeley, United States.; Molecular Biophysics and Integrative Bio-Imaging Division, Lawrence Berkeley National Laboratory, Berkeley, United States.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States., Patel AB; California Institute for Quantitative Biology, University of California, Berkeley, Berkeley, United States.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Biophysics Graduate Group, University of California, Berkeley, Berkeley, United States.

المصدر: ELife [Elife] 2022 Oct 20; Vol. 11. Date of Electronic Publication: 2022 Oct 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae Proteins*/metabolism, Nucleosomes/metabolism ; Cryoelectron Microscopy ; Histone Acetyltransferases/metabolism ; Acetylation

المؤلفون: Dilworth D; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada. david.dilworth@utoronto.ca.; BlueRock Therapeutics, Toronto, Ontario, Canada. david.dilworth@utoronto.ca., Hanley RP; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; C4 Therapeutics, Watertown, MA, USA., Ferreira de Freitas R; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Rua Arcturus 3, São Bernardo do Campo, Brazil., Allali-Hassani A; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Incyte, Wilmington, DE, USA., Zhou M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan, China., Mehta N; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Nurix Therapeutics, San Francisco, CA, USA., Marunde MR; EpiCypher Inc., Durham, NC, USA., Ackloo S; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Carvalho Machado RA; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Khalili Yazdi A; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Owens DDG; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Vu V; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Nie DY; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Alqazzaz M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Marcon E; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Li F; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Chau I; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Bolotokova A; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Qin S; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Life Science Research Center, Southern University of Science and Technology, Shenzhen, China., Lei M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan, China., Liu Y; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; College of Pharmaceutical Sciences, Soochow University, Suzhou, China., Szewczyk MM; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Dong A; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Kazemzadeh S; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Abramyan T; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Atomwise, San Francisco, CA, USA., Popova IK; EpiCypher Inc., Durham, NC, USA., Hall NW; EpiCypher Inc., Durham, NC, USA., Meiners MJ; EpiCypher Inc., Durham, NC, USA., Cheek MA; EpiCypher Inc., Durham, NC, USA., Gibson E; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Kireev D; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Greenblatt JF; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Keogh MC; EpiCypher Inc., Durham, NC, USA., Min J; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan, China., Brown PJ; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada. d.barsyte@utoronto.ca.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. d.barsyte@utoronto.ca., James LI; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. ingerman@email.unc.edu., Schapira M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada. matthieu.schapira@utoronto.ca.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. matthieu.schapira@utoronto.ca.

المصدر: Nature chemical biology [Nat Chem Biol] 2022 Jan; Vol. 18 (1), pp. 56-63. Date of Electronic Publication: 2021 Nov 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Protein Domains*, Cell Nucleolus/*metabolism , Histone-Lysine N-Methyltransferase/*metabolism , Molecular Probes/*chemistry , Repressor Proteins/*metabolism, Methylation ; Multiple Myeloma/metabolism ; Nucleosomes/metabolism

المؤلفون: Marunde MR; EpiCypher Inc., Durham, NC, USA., Popova IK; EpiCypher Inc., Durham, NC, USA., Weinzapfel EN; EpiCypher Inc., Durham, NC, USA., Keogh MC; EpiCypher Inc., Durham, NC, USA. mkeogh@epicypher.com.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2458, pp. 231-255.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Histones*/metabolism , Nucleosomes*, Chromatin/genetics ; Peptides/metabolism ; Protein Processing, Post-Translational