المؤلفون: Jain S; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Griffith JI; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota., Porath KA; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Rathi S; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota., Le J; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota., Pasa TI; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Decker PA; Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota., Gupta SK; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Hu Z; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Carlson BL; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Bakken K; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Burgenske DM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota., Feldsien TM; Development Sciences, AbbVie Inc., North Chicago, Illinois., Lefebvre DR; Development Sciences, AbbVie Inc., North Chicago, Illinois., Vaubel RA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Eckel-Passow JE; Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota., Reilly EB; Discovery Oncology, AbbVie Inc., North Chicago, Illinois., Elmquist WF; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Aug 01; Vol. 30 (15), pp. 3287-3297.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Glioblastoma*/drug therapy , Glioblastoma*/pathology , Glioblastoma*/metabolism , Immunoconjugates*/pharmacokinetics , Immunoconjugates*/pharmacology , Immunoconjugates*/administration & dosage , ErbB Receptors*/antagonists & inhibitors , Xenograft Model Antitumor Assays* , Antibodies, Monoclonal, Humanized*/administration & dosage , Antibodies, Monoclonal, Humanized*/pharmacokinetics , Bystander Effect*, Animals ; Humans ; Mice ; Brain Neoplasms/drug therapy ; Brain Neoplasms/pathology ; Cell Line, Tumor ; Female

المؤلفون: Chen J; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Shengjing Hospital of China Medical University, Shenyang 110004, China., Laverty DJ; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Talele S; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55905, USA., Bale A; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Carlson BL; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Porath KA; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Bakken KK; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Burgenske DM; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Decker PA; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA., Vaubel RA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA., Eckel-Passow JE; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA., Bhargava R; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.; Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Lou Z; Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA., Hamerlik P; AstraZeneca, Cambridge, UK., Harley B; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Elmquist WF; Department of Pharmaceutics, University of Minnesota, Minneapolis, MN 55905, USA., Nagel ZD; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Gupta SK; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.

المصدر: Science translational medicine [Sci Transl Med] 2024 Feb 14; Vol. 16 (734), pp. eadj5962. Date of Electronic Publication: 2024 Feb 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/metabolism , Glioblastoma*/drug therapy , Glioblastoma*/genetics , Glioblastoma*/radiotherapy , Pyridines* , Quinolones*, Humans ; Signal Transduction ; DNA Repair/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism

المؤلفون: Porath KA; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Regan MS; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Griffith JI; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Jain S; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Stopka SA; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Burgenske DM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Bakken KK; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Carlson BL; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Decker PA; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA., Vaubel RA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Dragojevic S; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Mladek AC; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Connors MA; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Hu Z; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., He L; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Kitange GJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Gupta SK; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Feldsien TM; Development Sciences, AbbVie Inc., North Chicago, Illinois, USA., Lefebvre DR; Development Sciences, AbbVie Inc., North Chicago, Illinois, USA., Agar NYR; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Eckel-Passow JE; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA., Reilly EB; Discovery Oncology, AbbVie Inc., North Chicago, Illinois, USA., Elmquist WF; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA.

المصدر: Neuro-oncology advances [Neurooncol Adv] 2022 Aug 24; Vol. 4 (1), pp. vdac130. Date of Electronic Publication: 2022 Aug 24 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755003 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-2498 (Electronic) Linking ISSN: 26322498 NLM ISO Abbreviation: Neurooncol Adv Subsets: PubMed not MEDLINE

المؤلفون: Rechberger JS; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN 55905, USA., Porath KA; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Zhang L; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA., Nesvick CL; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA., Schrecengost RS; Targepeutics, Inc., Hershey, PA 17033, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Daniels DJ; Department of Neurologic Surgery, Mayo Clinic, Rochester, MN 55905, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN 55905, USA.

المصدر: Pharmaceutics [Pharmaceutics] 2022 Apr 24; Vol. 14 (5). Date of Electronic Publication: 2022 Apr 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE

المؤلفون: Marin BM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Porath KA; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Jain S; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Kim M; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota, USA., Conage-Pough JE; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Oh JH; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota, USA., Miller CL; Department of Bioengineering, Stanford University, Stanford, California, USA., Talele S; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota, USA., Kitange GJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Tian S; Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA., Burgenske DM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Mladek AC; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Gupta SK; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Decker PA; Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA., McMinn MH; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA., Stopka SA; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Regan MS; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., He L; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Carlson BL; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Bakken K; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Burns TC; Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA., Parney IF; Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA., Giannini C; Department of Laboratory Medicine and Pathology; Mayo Clinic, Rochester, Minnesota, USA., Agar NYR; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Eckel-Passow JE; Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA., Cochran JR; Department of Bioengineering, Stanford University, Stanford, California, USA., Elmquist WF; Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota, USA., Vaubel RA; Department of Laboratory Medicine and Pathology; Mayo Clinic, Rochester, Minnesota, USA., White FM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA.

المصدر: Neuro-oncology [Neuro Oncol] 2021 Dec 01; Vol. 23 (12), pp. 2042-2053.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Brain Neoplasms*/drug therapy , Glioblastoma*/drug therapy , Immunoconjugates* , Pharmaceutical Preparations*, Antibodies, Monoclonal, Humanized ; Blood-Brain Barrier/metabolism ; Cell Line, Tumor ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Humans