المؤلفون: Khamri, W, Abeles, RD, Hou, TZ, Anderson, AE, El-Masry, A, Triantafyllou, E, Bernsmeier, C, Larsen, FS, Singanayagam, A, Kudo, N, Possamai, LA, Lebosse, F, Auzinger, G, Bernal, W, Willars, C, Weston, CJ, Lombardi, G, Wendon, J, Thursz, M, Antoniades, CG

المصدر: Khamri, W, Abeles, R D, Hou, T Z, Anderson, A E, El-Masry, A, Triantafyllou, E, Bernsmeier, C, Larsen, F S, Singanayagam, A, Kudo, N, Possamai, L A, Lebosse, F, Auzinger, G, Bernal, W, Willars, C, Weston, C J, Lombardi, G, Wendon, J, Thursz, M & Antoniades, C G 2017, ' Increased Expression of Cytotoxic T-Lymphocyte-Associated Protein 4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure ', Gastroenterology, vol. 153, no. 1, pp. 263-276.e8 . https://doi.org/10.1053/j.gastro.2017.03.023

مصطلحات موضوعية: Adult, digestive, oral, and skin physiology, CTLA-4 Antigen/immunology, Dendritic Cells, Adaptive Immunity, Middle Aged, Lymphocyte Activation, Coculture Techniques, Acetaminophen/toxicity, CD4 Lymphocyte Count, Mice, Antibodies/pharmacology, Shock, Septic/immunology, CD4-Positive T-Lymphocytes/immunology, Hepatocytes/secretion, Liver Cirrhosis/immunology, Animals, Humans, Liver Failure, Acute/immunology, Chemical and Drug Induced Liver Injury/blood, CD3 Complex/pharmacology, Acute-On-Chronic Liver Failure/immunology, Cells, Cultured, B7-1 Antigen/blood, Cell Proliferation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::271800c8716f6134bc659eaae9e47b25
https://curis.ku.dk/portal/da/publications/increased-expression-of-cytotoxic-tlymphocyteassociated-protein-4-by-t-cells-induced-by-b7-in-sera-reduces-adaptive-immunity-in-patients-with-acute-liver-failure(25c0eb5f-d438-47fb-a679-aba50ffb7221).html

المؤلفون: Gudd CLC; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK c.gudd@imperial.ac.uk., Mitchell E; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Atkinson SR; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Mawhin MA; Centre for Inflammatory Disease, Imperial College London, London, UK., Turajlic S; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Renal and Skin Units, The Royal Marsden NHS Foundation Trust, London, UK.; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London, UK., Larkin J; Renal and Skin Units, The Royal Marsden NHS Foundation Trust, London, UK.; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London, UK., Thursz MR; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Goldin RD; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Powell N; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Antoniades CG; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Woollard KJ; Centre for Inflammatory Disease, Imperial College London, London, UK., Possamai LA; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Triantafyllou E; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

المصدر: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 Apr 04; Vol. 12 (4). Date of Electronic Publication: 2024 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Monocytes* , Hepatitis*/drug therapy , Hepatitis*/etiology, Humans ; Mice ; Animals ; CD8-Positive T-Lymphocytes ; Toll-Like Receptor 9 ; Mice, Inbred C57BL

المؤلفون: Gudd CLC; Section of Hepatology and Gastroenterology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Sheth R; Institute of Liver Studies, Department of Inflammation Biology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom., Thursz MR; Section of Hepatology and Gastroenterology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.; Liver and Antiviral Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom., Triantafyllou E; Section of Hepatology and Gastroenterology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Possamai LA; Section of Hepatology and Gastroenterology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.; Liver and Antiviral Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.

المصدر: Seminars in liver disease [Semin Liver Dis] 2023 Nov; Vol. 43 (4), pp. 402-417. Date of Electronic Publication: 2023 Dec 15.

نوع المنشور: Review; Journal Article

بيانات الدورية: Publisher: Thieme Country of Publication: United States NLM ID: 8110297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-8971 (Electronic) Linking ISSN: 02728087 NLM ISO Abbreviation: Semin Liver Dis Subsets: MEDLINE

مواضيع طبية MeSH: Chemical and Drug Induced Liver Injury, Chronic*/etiology , Hepatitis* , Chemical and Drug Induced Liver Injury*/etiology, Humans ; Immune Checkpoint Inhibitors/adverse effects ; Immunotherapy/adverse effects

المؤلفون: Lo JW; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Cozzetto D; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Alexander JL; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Danckert NP; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Madgwick M; Organisms and Ecosystems, Earlham Institute, NR4 7UZ, Norwich, UK.; Gut Microbes and Health Programme, Quadram Institute Bioscience, NR4 7UQ, Norwich, UK., Knox N; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Sieh JYX; School of Immunology and Microbial Sciences, King's College London, London, SE1 9RT, UK., Olbei M; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.; Organisms and Ecosystems, Earlham Institute, NR4 7UZ, Norwich, UK.; Gut Microbes and Health Programme, Quadram Institute Bioscience, NR4 7UQ, Norwich, UK., Liu Z; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Ibraheim H; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Blanco JM; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Kudo H; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Seoane RC; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Possamai LA; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Goldin R; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Marchesi J; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK., Korcsmaros T; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.; Organisms and Ecosystems, Earlham Institute, NR4 7UZ, Norwich, UK.; Gut Microbes and Health Programme, Quadram Institute Bioscience, NR4 7UQ, Norwich, UK., Lord GM; School of Immunology and Microbial Sciences, King's College London, London, SE1 9RT, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9NT, UK., Powell N; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, W12 0NN, UK. npowell@ic.ac.uk.

المصدر: Nature communications [Nat Commun] 2023 Oct 23; Vol. 14 (1), pp. 6719. Date of Electronic Publication: 2023 Oct 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Colitis*/chemically induced , Interferon-gamma*/genetics, Animals ; Mice ; Cytokines ; Immune Checkpoint Inhibitors ; Lymphocytes

المؤلفون: Hong AS; Gastroenterology and Hepatology, Imperial College School of Medicine, London, GBR., Sarwar N; Medical Oncology, Department of Oncology, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, GBR., Goldin RD; Section for Pathology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, GBR., Dhar A; Gastroenterology and Hepatology, Department of Hepatology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, London, GBR., Possamai LA; Gastroenterology and Hepatology, Department of Hepatology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, London, GBR.

المصدر: Cureus [Cureus] 2022 Jul 05; Vol. 14 (7), pp. e26596. Date of Electronic Publication: 2022 Jul 05 (Print Publication: 2022).

نوع المنشور: Case Reports

بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE

المؤلفون: Gudd CLC; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK., Possamai LA; Department of Metabolism, Digestion & Reproduction, Imperial College London, London SW7 2AZ, UK.

المصدر: Cancers [Cancers (Basel)] 2022 Apr 10; Vol. 14 (8). Date of Electronic Publication: 2022 Apr 10.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Begum P; Lung Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom., Goldin RD; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, United Kingdom., Possamai LA; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, United Kingdom., Popat S; Lung Unit, Royal Marsden NHS Foundation Trust, London, United Kingdom.; Thoracic Oncology, The Institute of Cancer Research, London, United Kingdom.

المصدر: JTO clinical and research reports [JTO Clin Res Rep] 2021 Aug 02; Vol. 2 (9), pp. 100213. Date of Electronic Publication: 2021 Aug 02 (Print Publication: 2021).

نوع المنشور: Case Reports

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101769967 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-3643 (Electronic) Linking ISSN: 26663643 NLM ISO Abbreviation: JTO Clin Res Rep Subsets: PubMed not MEDLINE

المؤلفون: Gudd CLC; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Au L; Renal and Skin Units, The Royal Marsden Hospital National Health Service Foundation Trust, London, UK., Triantafyllou E; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Shum B; Renal and Skin Units, The Royal Marsden Hospital National Health Service Foundation Trust, London, UK., Liu T; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Nathwani R; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Kumar N; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Mukherjee S; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Dhar A; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Woollard KJ; Department of Immunology and Inflammation, Imperial College London, London, UK., Yone Y; Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London, UK., Pinato DJ; Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London, UK., Thursz MR; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Goldin RD; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Gore ME; Renal and Skin Units, The Royal Marsden Hospital National Health Service Foundation Trust, London, UK., Larkin J; Renal and Skin Units, The Royal Marsden Hospital National Health Service Foundation Trust, London, UK., Khamri W; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Antoniades CG; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK., Turajlic S; Renal and Skin Units, The Royal Marsden Hospital National Health Service Foundation Trust, London, UK., Possamai LA; Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK. Electronic address: l.possamai@imperial.ac.uk.

المصدر: Journal of hepatology [J Hepatol] 2021 Jul; Vol. 75 (1), pp. 177-189. Date of Electronic Publication: 2021 Feb 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

مواضيع طبية MeSH: Chemical and Drug Induced Liver Injury*/blood , Chemical and Drug Induced Liver Injury*/etiology , Chemical and Drug Induced Liver Injury*/immunology , Chemical and Drug Induced Liver Injury*/prevention & control, Antigens, CD/*immunology , Antigens, Differentiation, Myelomonocytic/*immunology , Antineoplastic Agents/*adverse effects , CD8-Positive T-Lymphocytes/*immunology , Immune Checkpoint Inhibitors/*adverse effects , Macrophages/*immunology , Receptors, CCR2/*immunology , Receptors, CCR7/*immunology , Receptors, Cell Surface/*immunology, Antineoplastic Agents/administration & dosage ; Drug Discovery ; Female ; Humans ; Immune Checkpoint Inhibitors/administration & dosage ; Immune Checkpoint Inhibitors/immunology ; Macrophage Activation/immunology ; Male ; Middle Aged ; T-Lymphocytes, Cytotoxic/immunology

المؤلفون: Triantafyllou E; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and.; Department of Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Gudd CL; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and.; Department of Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Mawhin MA; Department of Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Husbyn HC; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and., Trovato FM; Division of Transplantation Immunology and Mucosal Biology, King's College London, London, United Kingdom., Siggins MK; Department of Infectious Disease, and., O'Connor T; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and., Kudo H; Department of Metabolism, Digestion and Reproduction, Section of Pathology, Imperial College London, London, United Kingdom., Mukherjee SK; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and., Wendon JA; Division of Transplantation Immunology and Mucosal Biology, King's College London, London, United Kingdom., Bernsmeier C; Department of Biomedicine, University of Basel and University Centre for Gastrointestinal and Liver Diseases, Basel, Switzerland., Goldin RD; Department of Metabolism, Digestion and Reproduction, Section of Pathology, Imperial College London, London, United Kingdom., Botto M; Department of Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Khamri W; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and., McPhail MJ; Division of Transplantation Immunology and Mucosal Biology, King's College London, London, United Kingdom., Possamai LA; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and., Woollard KJ; Department of Immunology and Inflammation, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom., Antoniades CG; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and., Thursz MR; Department of Metabolism, Digestion and Reproduction, Section of Hepatology and Gastroenterology, and.

المصدر: The Journal of clinical investigation [J Clin Invest] 2021 Feb 15; Vol. 131 (4).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Bacteria/*immunology , Bacterial Infections/*immunology , Chemical and Drug Induced Liver Injury/*immunology , Immune Checkpoint Inhibitors/*pharmacology , Kupffer Cells/*immunology , Programmed Cell Death 1 Receptor/*antagonists & inhibitors, Acetaminophen/adverse effects ; Acetaminophen/therapeutic use ; Adult ; Animals ; Bacterial Infections/drug therapy ; Bacterial Infections/genetics ; Chemical and Drug Induced Liver Injury/drug therapy ; Chemical and Drug Induced Liver Injury/genetics ; Chemical and Drug Induced Liver Injury/microbiology ; Female ; Humans ; Kupffer Cells/microbiology ; Male ; Mice ; Mice, Knockout ; Middle Aged ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/immunology

المؤلفون: Fessas P; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, UK., Possamai LA; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital, London, UK., Clark J; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, UK., Daniels E; National Centre for HIV Malignancy, Department of Oncology, Chelsea and Westminster Hospital, London, UK., Gudd C; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital, London, UK., Mullish BH; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital, London, UK., Alexander JL; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, St Mary's Hospital, London, UK., Pinato DJ; Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, UK.

المصدر: Immunology [Immunology] 2020 Feb; Vol. 159 (2), pp. 167-177. Date of Electronic Publication: 2019 Nov 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Immunological/*adverse effects , Chemical and Drug Induced Liver Injury/*etiology , Endocrine System Diseases/*chemically induced , Gastrointestinal Diseases/*chemically induced , Immune Tolerance/*drug effects , Immunotherapy/*adverse effects , Lung Diseases/*chemically induced , Molecular Targeted Therapy/*adverse effects , Neoplasms/*drug therapy, Animals ; Chemical and Drug Induced Liver Injury/immunology ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/therapy ; Endocrine System Diseases/immunology ; Endocrine System Diseases/metabolism ; Endocrine System Diseases/therapy ; Gastrointestinal Diseases/immunology ; Gastrointestinal Diseases/metabolism ; Gastrointestinal Diseases/therapy ; Humans ; Lung Diseases/immunology ; Lung Diseases/metabolism ; Lung Diseases/therapy ; Neoplasms/immunology ; Neoplasms/metabolism ; Risk Factors ; Tumor Escape/drug effects