المؤلفون: Akhlaghpour M; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA., Haritunians T; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., More SK; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Thomas LS; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Stamps DT; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Dube S; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Li D; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Yang S; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Landers CJ; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Mengesha E; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Hamade H; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Murali R; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA., Potdar AA; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Wolf AJ; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA., Botwin GJ; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Khrom M; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Ananthakrishnan AN; Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts, USA., Faubion WA; Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA., Jabri B; Biological Sciences Division, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA., Lira SA; Immunology Institute, Mount Sinai Medical Center, New York, New York, USA., Newberry RD; Division of Gastroenterology, Washington Univ. Sch. of Medicine, Saint Louis, Missouri, USA., Sandler RS; Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, North Carolina, USA., Sartor RB; Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, North Carolina, USA., Xavier RJ; Broad Institute Harvard, Cambridge, Massachusetts, USA., Brant SR; Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA., Cho JH; Genetics and Genomics Sciences, Mt Sinai School of Medicine, New York, New York, USA., Duerr RH; Departments of Medicine and Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Lazarev MG; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Rioux JD; Faculty of Medicine, Universite de Montreal, Montreal, Québec, Canada., Schumm LP; Dept of Health Studies, University of Chicago, Chicago, Illinois, USA., Silverberg MS; Division of Gastroenterology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada., Zaghiyan K; Division of Colorectal Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA., Fleshner P; Division of Colorectal Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA., Melmed GY; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Vasiliauskas EA; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Ha C; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Rabizadeh S; Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, USA., Syal G; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Bonthala NN; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Ziring DA; Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, USA., Targan SR; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Long MD; Medicine, University of North Carolina, Chapel Hill, North Carolina, USA., McGovern DPB; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA kathrin.michelsen@cshs.org Dermot.McGovern@cshs.org.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA., Michelsen KS; F. Widjaja Inflammatory Bowel Disease Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA kathrin.michelsen@cshs.org Dermot.McGovern@cshs.org.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.

مؤلفون مشاركون: International IBD Genetics Consortium

المصدر: Gut [Gut] 2023 Nov; Vol. 72 (11), pp. 2068-2080. Date of Electronic Publication: 2023 Apr 20.

نوع المنشور: Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE

مواضيع طبية MeSH: Complement Factor B*/genetics , Crohn Disease*/complications, Humans ; Quality of Life ; Follow-Up Studies ; Phagocytosis

المؤلفون: Khrom M; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Li D; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Naito T; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Lee HS; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, Korea., Botwin GJ; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Potdar AA; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Boucher G; Research Center, Montreal Heart Institute, Montreal, Quebec, Canada., Yang S; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Mengesha E; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Dube S; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Song K; Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, Korea., McGovern DPB; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Haritunians T; F. Widjaja Inflammatory Bowel Disease Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

مؤلفون مشاركون: NIDDK Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium

المصدر: Inflammatory bowel diseases [Inflamm Bowel Dis] 2023 Oct 03; Vol. 29 (10), pp. 1622-1632.

نوع المنشور: Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9508162 Publication Model: Print Cited Medium: Internet ISSN: 1536-4844 (Electronic) Linking ISSN: 10780998 NLM ISO Abbreviation: Inflamm Bowel Dis Subsets: MEDLINE

مواضيع طبية MeSH: Inflammatory Bowel Diseases*/genetics , Crohn Disease*/genetics , Colitis, Ulcerative*/genetics, Humans ; Female ; Male ; Genetic Predisposition to Disease ; Sex Characteristics ; Genome-Wide Association Study

المؤلفون: Shiao SL; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address: stephen.shiao@cshs.org., Kershaw KM; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Limon JJ; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., You S; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Yoon J; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Ko EY; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Guarnerio J; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Potdar AA; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., McGovern DPB; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Bose S; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Dar TB; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Noe P; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Lee J; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Kubota Y; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Maymi VI; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Davis MJ; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Henson RM; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Choi RY; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Yang W; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Tang J; Genomics Core, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Gargus M; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Prince AD; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Zumsteg ZS; Department of Radiation Oncology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA., Underhill DM; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

المصدر: Cancer cell [Cancer Cell] 2021 Sep 13; Vol. 39 (9), pp. 1202-1213.e6. Date of Electronic Publication: 2021 Jul 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Antifungal Agents/*administration & dosage , Bacteria/*classification , Breast Neoplasms/*therapy , Fungi/*drug effects , Lectins, C-Type/*genetics , Melanoma/*therapy, Animals ; Antifungal Agents/pharmacology ; Bacteria/immunology ; Breast Neoplasms/immunology ; Breast Neoplasms/microbiology ; Combined Modality Therapy ; Down-Regulation ; Female ; Fungi/classification ; Fungi/immunology ; Gastrointestinal Microbiome/drug effects ; Gastrointestinal Microbiome/radiation effects ; Gene Expression Regulation, Neoplastic/radiation effects ; Humans ; Melanoma/immunology ; Melanoma/microbiology ; Mice ; Symbiosis ; T-Lymphocytes/metabolism ; Tumor-Associated Macrophages/metabolism ; Up-Regulation/drug effects ; Up-Regulation/radiation effects ; Xenograft Model Antitumor Assays

المؤلفون: Potdar AA; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Dube S; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Naito T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Li K; Janssen Research and Development, LLC, Spring House, Pennsylvania., Botwin G; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Haritunians T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Li D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Casero D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Yang S; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Bilsborough J; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Perrigoue JG; Janssen Research and Development, LLC, Spring House, Pennsylvania., Denson LA; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Cincinnati College of Medicine and the Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Daly M; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Targan SR; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Fleshner P; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Braun J; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Kugathasan S; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; Children's Healthcare of Atlanta, Atlanta, Georgia., Stappenbeck TS; Department of Inflammation and Immunity, Cleveland Clinic, Cleveland, Ohio., McGovern DPB; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California. Electronic address: dermot.mcgovern@cshs.org.

المصدر: Gastroenterology [Gastroenterology] 2021 Feb; Vol. 160 (3), pp. 809-822.e7. Date of Electronic Publication: 2020 Nov 05.

نوع المنشور: Journal Article; Multicenter Study

بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE

مواضيع طبية MeSH: Angiotensin-Converting Enzyme 2/*metabolism , Anti-Inflammatory Agents/*therapeutic use , Colitis, Ulcerative/*drug therapy , Crohn Disease/*drug therapy , Intestines/*drug effects , Tumor Necrosis Factor Inhibitors/*therapeutic use , Tumor Necrosis Factor-alpha/*antagonists & inhibitors, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Angiotensin-Converting Enzyme 2/genetics ; Anti-Inflammatory Agents/adverse effects ; COVID-19/enzymology ; COVID-19/immunology ; COVID-19/virology ; Case-Control Studies ; Child ; Child, Preschool ; Colitis, Ulcerative/enzymology ; Colitis, Ulcerative/genetics ; Colitis, Ulcerative/immunology ; Crohn Disease/enzymology ; Crohn Disease/genetics ; Crohn Disease/immunology ; Databases, Genetic ; Female ; Gene Expression Regulation, Enzymologic ; Host-Pathogen Interactions ; Humans ; Intestines/enzymology ; Intestines/immunology ; Male ; Middle Aged ; North America ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Virus/metabolism ; SARS-CoV-2/enzymology ; SARS-CoV-2/immunology ; Severity of Illness Index ; Treatment Outcome ; Tumor Necrosis Factor Inhibitors/adverse effects ; Tumor Necrosis Factor-alpha/metabolism ; Young Adult

SCR Disease Name: Pediatric Crohn's disease; Pediatric ulcerative colitis

المؤلفون: Potdar AA; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Dube S; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Naito T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Botwin G; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Haritunians T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Li D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Yang S; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Bilsborough J; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Denson LA; Division of Pediatric Gastroenterology, Hepatology, and nutrition, Department of Pediatrics, University of Cincinnati college of Medicine and the Cincinnati children's Hospital Medical center, Cincinnati, OH, USA., Daly M; Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Targan SR; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Fleshner P; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Braun J; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Kugathasan S; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA; Children's Healthcare of Atlanta, Atlanta, GA, USA., Stappenbeck TS; Department of Inflammation and Immunity, Cleveland Clinic, Cleveland, Ohio, USA., McGovern DPB; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2020 Apr 23. Date of Electronic Publication: 2020 Apr 23.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

المؤلفون: Potdar AA; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Li D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Haritunians T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., VanDussen KL; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, USA., Fiorino MF; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Liu TC; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, USA., Stappenbeck TS; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri, USA., Fleshner P; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Targan SR; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., McGovern DPB; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Bilsborough J; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

المصدر: Journal of Crohn's & colitis [J Crohns Colitis] 2019 Aug 14; Vol. 13 (8), pp. 1055-1066.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101318676 Publication Model: Print Cited Medium: Internet ISSN: 1876-4479 (Electronic) Linking ISSN: 18739946 NLM ISO Abbreviation: J Crohns Colitis Subsets: MEDLINE

مواضيع طبية MeSH: Crohn Disease*/diagnosis , Crohn Disease*/epidemiology , Crohn Disease*/genetics , Crohn Disease*/therapy , Ileum*/metabolism , Ileum*/pathology , Ileum*/surgery , Pharmacogenomic Testing*, Anti-Inflammatory Agents/*pharmacology , Signal Transduction/*genetics, Adolescent ; Adult ; Child ; Digestive System Surgical Procedures/methods ; Female ; Gene Expression Profiling/methods ; Gene Expression Profiling/statistics & numerical data ; Genome-Wide Association Study ; Humans ; Male ; Patient Selection ; Severity of Illness Index ; United States

المؤلفون: Tsuda M; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.; Food and Physiological Functions Laboratory, College of Bioresource Sciences, Nihon University, 1866 Kameino Fujisawa-shi Kanagawa, Tokyo, 252-0880, Japan., Hamade H; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Thomas LS; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Salumbides BC; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Potdar AA; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Wong MH; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Nunnelee JS; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Stamps JT; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Neutzsky-Wulff AV; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Barrett RJ; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.; Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Wang Y; Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Tang J; Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Funari VA; Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Targan SR; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Michelsen KS; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA. kathrin.michelsen@cshs.org.

المصدر: Mucosal immunology [Mucosal Immunol] 2019 May; Vol. 12 (3), pp. 644-655. Date of Electronic Publication: 2019 Jan 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3456 (Electronic) Linking ISSN: 19330219 NLM ISO Abbreviation: Mucosal Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Basic-Leucine Zipper Transcription Factors/*metabolism , Inflammation/*immunology , Inflammatory Bowel Diseases/*immunology , Interleukin-9/*metabolism , Repressor Proteins/*metabolism , T-Lymphocytes, Helper-Inducer/*immunology, Animals ; Antibodies, Neutralizing/metabolism ; Basic-Leucine Zipper Transcription Factors/genetics ; Cell Differentiation ; Cells, Cultured ; Humans ; Interleukin-9/genetics ; Interleukin-9/immunology ; Lymphocyte Activation ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Promoter Regions, Genetic/genetics ; Protein Binding ; Repressor Proteins/genetics ; Signal Transduction ; Tumor Necrosis Factor Ligand Superfamily Member 15/metabolism

المؤلفون: Eswarappa SM; From the Department of Biochemistry, Indian Institute of Science, Bengaluru 560012, India, sandeep@iisc.ac.in., Potdar AA; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, and., Sahoo S; From the Department of Biochemistry, Indian Institute of Science, Bengaluru 560012, India., Sankar S; From the Department of Biochemistry, Indian Institute of Science, Bengaluru 560012, India., Fox PL; Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195 foxp@ccf.org.

المصدر: The Journal of biological chemistry [J Biol Chem] 2018 Dec 07; Vol. 293 (49), pp. 19148-19156. Date of Electronic Publication: 2018 Oct 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Evolution, Molecular* , Models, Chemical*, Amino Acyl-tRNA Synthetases/*chemistry , Bacterial Proteins/*chemistry, Amino Acyl-tRNA Synthetases/genetics ; Amino Acyl-tRNA Synthetases/metabolism ; Animals ; Bacteria/genetics ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Citric Acid Cycle ; Gene Fusion ; Glutamate-tRNA Ligase/chemistry ; Glutamate-tRNA Ligase/genetics ; Glutamate-tRNA Ligase/metabolism ; Glutamic Acid/chemistry ; Glutamic Acid/metabolism ; Ketoglutaric Acids/chemistry ; Ketoglutaric Acids/metabolism ; Proline/chemistry ; Proline/metabolism ; Protein Biosynthesis/genetics

المؤلفون: Li D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Haritunians T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Landers C; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Potdar AA; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Yang S; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., Huang H; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Schumm LP; Department of Public Health Sciences, University of Chicago, Chicago, Illinois., Daly M; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Targan SR; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California., McGovern DPB; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California.

المصدر: Inflammatory bowel diseases [Inflamm Bowel Dis] 2018 Oct 12; Vol. 24 (11), pp. 2413-2422.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9508162 Publication Model: Print Cited Medium: Internet ISSN: 1536-4844 (Electronic) Linking ISSN: 10780998 NLM ISO Abbreviation: Inflamm Bowel Dis Subsets: MEDLINE

مواضيع طبية MeSH: Polymorphism, Single Nucleotide*, Colitis, Ulcerative/*pathology , Crohn Disease/*classification , Crohn Disease/*pathology, Adolescent ; Adult ; Child ; Child, Preschool ; Cohort Studies ; Colitis, Ulcerative/epidemiology ; Colitis, Ulcerative/genetics ; Crohn Disease/epidemiology ; Crohn Disease/genetics ; Female ; Follow-Up Studies ; Genotype ; Humans ; Male ; Middle Aged ; Phenotype ; Prognosis ; Risk Factors ; United States/epidemiology ; Young Adult

المؤلفون: Sarkar J; Pricewaterhouse Coopers LLP, New York, NY, United States of America., Potdar AA; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States of America., Saidel GM; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States of America.

المصدر: PLoS computational biology [PLoS Comput Biol] 2018 Apr 16; Vol. 14 (4), pp. e1006060. Date of Electronic Publication: 2018 Apr 16 (Print Publication: 2018).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

مواضيع طبية MeSH: Models, Biological*, Anemia/*metabolism , Anemia/*therapy , Iron/*metabolism , Renal Insufficiency, Chronic/*complications , Renal Insufficiency, Chronic/*metabolism, Anemia/etiology ; Biological Transport, Active ; Bone Marrow/metabolism ; Cation Transport Proteins/metabolism ; Computational Biology ; Epoetin Alfa/therapeutic use ; Erythrocytes/metabolism ; Erythropoietin/metabolism ; Hepcidins/metabolism ; Humans ; Iron/blood ; Iron-Dextran Complex/therapeutic use ; Liver/metabolism ; Mononuclear Phagocyte System/metabolism ; Transferrin/metabolism