المؤلفون: JOE R. CANNON, PRAKASH VACHASPATI, YANG YUAN

المصدر: Drug Metabolism Handbook. :41-101

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::047ef6678bbdd153038a5f779f8f6ffd
https://doi.org/10.1002/9781119851042.ch4

المؤلفون: Ying Wei Ivan Low, Prakash Vachaspati, Francesca Blasco

المصدر: European Journal of Pharmaceutical Sciences. 92:110-116

مصطلحات موضوعية: 0301 basic medicine, Octanol, Analyte, Chromatography, Serial dilution, Chemistry, Analytical chemistry, Water, Pharmaceutical Science, 1-Octanol, 030226 pharmacology & pharmacy, High-Throughput Screening Assays, Partition coefficient, Matrix (chemical analysis), 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Lipophilicity, Dimethyl Sulfoxide, Orders of magnitude (data), Throughput (business)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3e4e5e7f74f4f704da07786bcc8d92
https://doi.org/10.1016/j.ejps.2016.06.024

المؤلفون: Vaishali Humnabadkar, Claire Sadler, Tanjore S. Balganesh, Prakash Vachaspati, Disha Awasthy, Manoranjan Panda, Mick D. Fellows, Parvinder Kaur, Stewart T. Cole, Florence Pojer, Vasan K. Sambandamurthy, João Neres, Sreevalli Sharma, V. Balasubramanian, Kannan Murugan, Meenakshi Mallya, Suresh Rudrapatna, Balachandra Bandodkar, Sudhir Landge, Bheemarao G. Ugarkar, Jyothi Mahadevaswamy, Kavitha Nagalapur, Amrita B. Mullick, Vasanthi Ramachandran, Anirban Ghosh, Venkita Subbulakshmi

المصدر: Bioorganic & Medicinal Chemistry. 23:7694-7710

مصطلحات موضوعية: Tuberculosis, medicine.drug_class, Clinical Biochemistry, Antitubercular Agents, Pharmaceutical Science, Pharmacology, Antimycobacterial, Biochemistry, Mycobacterium tuberculosis, Structure-Activity Relationship, chemistry.chemical_compound, Bacterial Proteins, Drug Discovery, medicine, Humans, Structure–activity relationship, HATU, Benzothiazoles, Molecular Biology, chemistry.chemical_classification, Oxidase test, biology, Chemistry, Organic Chemistry, biology.organism_classification, medicine.disease, Molecular Docking Simulation, Alcohol Oxidoreductases, Enzyme, Benzothiazole, Drug Design, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d84f5aa2e5195a52048dc8416022f28
https://doi.org/10.1016/j.bmc.2015.11.017

المؤلفون: Eknath Bellale, Maruti Naik, Varun VB, Anisha Ambady, Ashwini Narayan, Sudha Ravishankar, Vasanthi Ramachandran, Parvinder Kaur, Robert McLaughlin, James Whiteaker, Sapna Morayya, Supreeth Guptha, Sreevalli Sharma, Anandkumar Raichurkar, Disha Awasthy, Vijayshree Achar, Prakash Vachaspati, Balachandra Bandodkar, Manoranjan Panda, Monalisa Chatterji

المصدر: Journal of medicinal chemistry. 57(15)

مصطلحات موضوعية: medicine.drug_class, Antitubercular Agents, Virulence, Drug resistance, Microbial Sensitivity Tests, Pharmacology, Antimycobacterial, Polymorphism, Single Nucleotide, Mycobacterium tuberculosis, Small Molecule Libraries, Mice, Structure-Activity Relationship, Bacterial Proteins, Drug Discovery, Drug Resistance, Bacterial, medicine, Structure–activity relationship, Animals, Humans, Ligand efficiency, biology, Drug discovery, Chemistry, biology.organism_classification, Two-component regulatory system, High-Throughput Screening Assays, Thiazoles, Biochemistry, Mutation, Molecular Medicine, Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1293e4207ed6ffc8afc4b8f8153dde09
https://pubmed.ncbi.nlm.nih.gov/24967731

المؤلفون: Sunita M. de Sousa, C. N. Naveen Kumar, Anandkumar Raichurkar, Kale Manoj Ganpat, Krishna Koushik, M. R. Manjunatha, David Waterson, Vasan K. Sambandamurthy, Vikas Shinde, K. N. Mahesh Kumar, Jitendar Reddy, Julie A. Tucker, Prashanti Madhavapeddi, Derek Ogg, Sandeep R. Ghorpade, Shubhada Barde, Halesha D. Basavarajappa, Shahul Hameed P, Samit Ganguly, V. K. Ramya, Lalit kumar Jena, Vijender Panduga, Vijaykamal Ahuja, Prakash Vachaspati, David C. McKinney, Jayashree Giridhar, Anirban Ghosh, Sheshagiri Gaonkar, Supreeth Guptha, P. Ann Boriack-Sjodin, Suresh Rudrapatna, Sreevalli Sharma, Usha Kranthi, Vaishali Humnabadkar

المصدر: Journal of medicinal chemistry. 56(21)

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Pyridines, Antitubercular Agents, DNA gyrase, Mycobacterium tuberculosis, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Drug Discovery, Ribose, Structure–activity relationship, Animals, Topoisomerase II Inhibitors, Tuberculosis, Urea, Homology modeling, IC50, Mice, Inbred BALB C, biology, Dose-Response Relationship, Drug, Molecular Structure, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, In vitro, Disease Models, Animal, chemistry, Biochemistry, DNA Gyrase, Molecular Medicine, Pharmacophore

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97722b62636e6c49a04e6567ae3fc13
https://pubmed.ncbi.nlm.nih.gov/24088190

المؤلفون: Sreedhar Madishetti, Jitendar Reddy, Prakash Vachaspati

المصدر: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 47(2)

مصطلحات موضوعية: Male, Mice, Inbred BALB C, Drug discovery, Chemistry, High-throughput screening, Drug Evaluation, Preclinical, Pharmaceutical Science, Administration, Oral, PK Parameters, Pharmacology, Mice, Pharmacokinetics, Pharmaceutical Preparations, Screening method, Animals, Administration, Intravenous, Rifampin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4578a2c74a58faa732ef95fea42dd9d
https://pubmed.ncbi.nlm.nih.gov/22789493