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المؤلفون: Sarah M. Tindall, Karen Swift, Simon V. Avery, Kevin C. F. Fone, Farida Hanim Islahudin, Kang Nee Ting, Richard J. Pleass, Ian R. Mellor, Hans Erik Mølager Christensen
المصدر: Islahudin, F, Tindall, S M, Mellor, I R, Swift, K, Christensen, H E M, Fone, K C F, Pleass, R J, Ting, K-N & Avery, S V 2014, ' The antimalarial drug quinine interferes with serotonin biosynthesis and action ', Scientific Reports, vol. 4, 3618 . https://doi.org/10.1038/srep03618
Scientific Reportsمصطلحات موضوعية: Kynurenine pathway, 60504, Parasitology - Medical, plasma blood and lymphatics, 10060, Biochemistry studies - General, Tryptophan Hydroxylase, Pharmacology, Fungi Plantae (Fungi, Microorganisms, Nonvascular Plants, Plants) - Ascomycetes [15100] Saccharomyces cerevisiae species, Neuroblastoma, chemistry.chemical_compound, FALCIPARUM-MALARIA, qv_257, qv_256, BRAIN, Neurotransmitter, 15002, Blood - Blood and lymph studies, Quinine, 22002, Pharmacology - General, 36008, Medical and clinical microbiology - Mycology, Multidisciplinary, TRYPTOPHAN-HYDROXYLASE, TPH2, PLASMA, 38510, Chemotherapy - Antiparasitic agents, PROLIFERATION, 38502, Chemotherapy - General, methods and metabolism, Hematology, 12512, Pathology - Therapy, 15006, Blood - Blood, lymphatic and reticuloendothelial pathologies, 60502, Parasitology - General, 15004, Blood - Blood cell studies, RECEPTORS, qv_126, Biochemistry, Serotonin Production, DEPLETION, drug development, enzyme mechanisms, malaria, mechanism of action, BEHAVIOR, medicine.drug, Serotonin, quinine 130-95-0 antiinfective-drug, antiparasitic-drug, Fungi Plantae (Fungi, Microorganisms, Nonvascular Plants, Plants) - Fungi Imperfecti or Deuteromycetes [15500] Candida albicans species, INHIBITION, neurotransmitter serotonin-5 5-HT receptor synthesis, Saccharomyces cerevisiae, Biology, Human Medicine, Medical Sciences, qv_38, 22005, Pharmacology - Clinical pharmacology, Article, Antimalarials, KYNURENINE PATHWAY, SDG 3 - Good Health and Well-being, Cell Line, Tumor, medicine, Humans, tryptophan 73-22-3, Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] SHSY5Y cell line cell_line human neuroblastoma cells, 10064, Biochemistry studies - Proteins, peptides and amino acids, Tryptophan, Tryptophan hydroxylase, wc_750, chemistry, 02508, Cytology - Human, Parasitology, malaria Malaria (MeSH) blood and lymphatic disease, parasitic disease drug therapy, symptom, MULTIDISCIPLINARY, tryptophan hydroxylase TPH2 9037-21-2 EC 1.14.16.4
وصف الملف: application/pdf; PDF
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2مورد إلكتروني
المصدر: Islahudin , F , Tindall , S M , Mellor , I R , Swift , K , Christensen , H E M , Fone , K C F , Pleass , R J , Ting , K-N & Avery , S V 2014 , ' The antimalarial drug quinine interferes with serotonin biosynthesis and action ' , Scientific Reports , vol. 4 , 3618 .
مصطلحات الفهرس: MULTIDISCIPLINARY, TRYPTOPHAN-HYDROXYLASE, KYNURENINE PATHWAY, FALCIPARUM-MALARIA, RECEPTORS, BRAIN, DEPLETION, BEHAVIOR, PROLIFERATION, INHIBITION, PLASMA, malaria Malaria (MeSH) blood and lymphatic disease, parasitic disease drug therapy, symptom, Fungi Plantae (Fungi, Microorganisms, Nonvascular Plants, Plants) - Ascomycetes [15100] Saccharomyces cerevisiae species, Fungi Plantae (Fungi, Microorganisms, Nonvascular Plants, Plants) - Fungi Imperfecti or Deuteromycetes [15500] Candida albicans species, Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] SHSY5Y cell line cell_line human neuroblastoma cells, neurotransmitter serotonin-5 5-HT receptor synthesis, quinine 130-95-0 antiinfective-drug, antiparasitic-drug, tryptophan 73-22-3, tryptophan hydroxylase TPH2 9037-21-2 EC 1.14.16.4, 02508, Cytology - Human, 10060, Biochemistry studies - General, 10064, Biochemistry studies - Proteins, peptides and amino acids, 12512, Pathology - Therapy, 15002, Blood - Blood and lymph studies, 15004, Blood - Blood cell studies, 15006, Blood - Blood, lymphatic and reticuloendothelial pathologies, 22002, Pharmacology - General, 22005, Pharmacology - Clinical pharmacology, 36008, Medical and clinical microbiology - Mycology, 38502, Chemotherapy - General, methods and metabolism, 38510, Chemotherapy - Antiparasitic agents, 60502, Parasitology - General, 60504, Parasitology - Medical, Human Medicine, Medical Sciences, plasma blood and lymphatics, Hematology, Parasitology, Pharmacology, dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being, article
URL:
https://orbit.dtu.dk/en/publications/621d297e-f2c8-43c5-a64e-39796a140f24 https://doi.org/10.1038/srep03618 https://backend.orbit.dtu.dk/ws/files/96835030/scientific_reports.pdf