المؤلفون: Giannikou K; Cancer Genetics Laboratory, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Cancer Genome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology and Oncology, Cancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA., Klonowska K; Cancer Genetics Laboratory, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Cancer Genome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tsuji J; Genomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wu S; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Zhu Z; Cancer Genetics Laboratory, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Probst CK; Cancer Genetics Laboratory, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Neurological Sciences, Larner College of Medicine, University of Vermont, Burlighton, VT, USA., Kao KZ; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Wu CL; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Rodig S; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Marino-Enriquez A; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Zen Y; Department of Diagnostic Pathology, Kobe University Hospital, Kobe, Japan.; Institute of Liver Studies, King's College Hospital, London, UK., Schaefer IM; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Kwiatkowski DJ; Cancer Genetics Laboratory, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

المصدر: Histopathology [Histopathology] 2023 Oct; Vol. 83 (4), pp. 569-581. Date of Electronic Publication: 2023 Sep 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 7704136 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2559 (Electronic) Linking ISSN: 03090167 NLM ISO Abbreviation: Histopathology Subsets: MEDLINE

مواضيع طبية MeSH: Angiomyolipoma*/genetics , Gastrointestinal Neoplasms* , Liver Neoplasms*/genetics , Tuberous Sclerosis Complex 2 Protein*/genetics, Humans ; Macrophages ; Mutation ; Tumor Microenvironment

المؤلفون: Knipe RS; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Nurunnabi M; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Probst CK; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Spinney JJ; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Abe E; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Bose RJC; Biomedical Research and Translational Medicine, Masonic Medical Research Institute, Utica, New York., Ha K; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Biomedical Research and Translational Medicine, Masonic Medical Research Institute, Utica, New York., Logue A; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Nguyen T; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Servis R; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts., Drummond M; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Haring A; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Brazee PL; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Medoff BD; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Andrew M. Tager Fibrosis Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., McCarthy JR; Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Biomedical Research and Translational Medicine, Masonic Medical Research Institute, Utica, New York.

المصدر: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Feb 01; Vol. 324 (2), pp. L190-L198. Date of Electronic Publication: 2023 Jan 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1504 (Electronic) Linking ISSN: 10400605 NLM ISO Abbreviation: Am J Physiol Lung Cell Mol Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Transcription Factors*/metabolism , Pulmonary Fibrosis*/chemically induced , Pulmonary Fibrosis*/drug therapy , Pulmonary Fibrosis*/prevention & control, Humans ; Animals ; Mice ; Myofibroblasts/metabolism ; Serum Response Factor/metabolism ; rho-Associated Kinases/metabolism ; Fibrosis ; Lung/metabolism ; Nanotechnology ; Cell Differentiation

المؤلفون: Axelsson Raja A; Department of Genetics, Harvard Medical School, Boston, MA 02115.; Department of Cardiology, Copenhagen University Hospital Rigshospitalet, 2100 Copenhagen, Denmark., Wakimoto H; Department of Genetics, Harvard Medical School, Boston, MA 02115., DeLaughter DM; Department of Genetics, Harvard Medical School, Boston, MA 02115., Reichart D; Department of Genetics, Harvard Medical School, Boston, MA 02115., Gorham J; Department of Genetics, Harvard Medical School, Boston, MA 02115., Conner DA; Department of Genetics, Harvard Medical School, Boston, MA 02115., Lun M; Department of Genetics, Harvard Medical School, Boston, MA 02115., Probst CK; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Fibrosis Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Sakai N; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Fibrosis Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Division of Nephrology, Kanazawa University, Kanazawa, 920-1192 Japan., Knipe RS; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Fibrosis Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Montesi SB; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Shea B; Division of Pulmonary, Critical Care and Sleep Medicine, Albert Medical School of Brown University, Providence, RI 02903., Adam LP; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08540., Leinwand LA; Biofrontiers Institute, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80302., Wan W; Biofrontiers Institute, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80302., Choi ES; Biofrontiers Institute, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80302., Lindberg EL; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany., Patone G; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany., Noseda M; National Heart and Lung Institute, British Heart Foundation Centre of Regenerative Medicine, British Heart Foundation Centre of Research Excellence, Imperial College London, London SW7 2AZ, United Kingdom., Hübner N; Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.; Charité-Universitätsmedizin, Berlin Institute of Health, 10117 Berlin, Germany.; German Centre for Cardiovascular Research, Partner Site Berlin, 13347 Berlin, Germany., Seidman CE; Department of Genetics, Harvard Medical School, Boston, MA 02115.; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA 02115.; HHMI, Chevy Chase, MD 20815., Tager AM; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Fibrosis Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114., Seidman JG; Department of Genetics, Harvard Medical School, Boston, MA 02115., Ho CY; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA 02115.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jul 12; Vol. 119 (28), pp. e2204174119. Date of Electronic Publication: 2022 Jul 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Cardiomyopathy, Hypertrophic*/genetics , Cardiomyopathy, Hypertrophic*/pathology, Receptors, Lysophosphatidic Acid/*genetics, Animals ; Carrier Proteins ; Disease Models, Animal ; Endothelial Cells/pathology ; Fibrosis ; Hypertrophy/pathology ; Mice

المؤلفون: Knipe RS; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Spinney JJ; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Abe EA; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Probst CK; Boston University School of Medicine, Boston University, Boston, Massachusetts., Franklin A; The MGH Institute of Health Professions, and., Logue A; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Giacona F; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Drummond M; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Griffith J; Division of Pulmonary and Critical Care Medicine.; Center for Immunology and Inflammatory Diseases., Brazee PL; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Hariri LP; Andrew M. Tager Fibrosis Research Center.; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Montesi SB; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center., Black KE; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Hla T; Vascular Biology Program, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts., Kuo A; Vascular Biology Program, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts., Cartier A; Vascular Biology Program, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts., Engelbrecht E; University of Louisville School of Medicine, Louisville, Kentucky., Christoffersen C; Department of Clinical Biochemistry, Rigshospitalet, and Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; and., Shea BS; Division of Pulmonary, Critical Care, and Sleep Medicine, Rhode Island Hospital and Alpert Medical School, Providence, Rhode Island., Tager AM; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases., Medoff BD; Division of Pulmonary and Critical Care Medicine.; Andrew M. Tager Fibrosis Research Center.; Center for Immunology and Inflammatory Diseases.

المصدر: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2022 Jan; Vol. 66 (1), pp. 38-52.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Capillary Permeability*, Endothelial Cells/*metabolism , Idiopathic Pulmonary Fibrosis/*metabolism , Idiopathic Pulmonary Fibrosis/*pathology , Sphingosine-1-Phosphate Receptors/*metabolism, Animals ; Bleomycin ; Blood Coagulation ; Gene Deletion ; Idiopathic Pulmonary Fibrosis/blood ; Lung/blood supply ; Lung/pathology ; Lysophospholipids/blood ; Mice, Inbred C57BL ; Mice, Transgenic ; Phenotype ; RNA-Seq ; Single-Cell Analysis ; Sphingosine/analogs & derivatives ; Sphingosine/blood ; Mice

المؤلفون: Hernandez JOR; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA., Wang X; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA., Vazquez-Segoviano M; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA., Lopez-Marfil M; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA., Sobral-Reyes MF; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA., Moran-Horowich A; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA., Sundberg M; Rosamund Zander Stone Translational Neuroscience Center, Department of Neurology, Boston Children's Hospital, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA., Lopez-Cantu DO; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA., Probst CK; Cancer Genetics Lab, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Center for LAM Research and Clinical Care, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA., Ruiz-Esparza GU; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA., Giannikou K; Harvard Medical School, Boston, MA, 02115, USA.; Cancer Genetics Lab, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Center for LAM Research and Clinical Care, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA., Abdi R; Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Henske EP; Harvard Medical School, Boston, MA, 02115, USA.; Cancer Genetics Lab, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Center for LAM Research and Clinical Care, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA., Kwiatkowski DJ; Harvard Medical School, Boston, MA, 02115, USA.; Cancer Genetics Lab, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Center for LAM Research and Clinical Care, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA., Sahin M; Rosamund Zander Stone Translational Neuroscience Center, Department of Neurology, Boston Children's Hospital, Boston, MA, 02115, USA.; Harvard Medical School, Boston, MA, 02115, USA., Lemos DR; Renal Division, Brigham and Women's Hospital, Boston, MA, 02115, USA. dlemos@bwh.harvard.edu.; Harvard Medical School, Boston, MA, 02115, USA. dlemos@bwh.harvard.edu.; Harvard Stem Cell Institute, Cambridge, MA, 02138, USA. dlemos@bwh.harvard.edu.

المصدر: Nature communications [Nat Commun] 2021 Nov 11; Vol. 12 (1), pp. 6496. Date of Electronic Publication: 2021 Nov 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Phosphopyruvate Hydratase/*metabolism , Tuberous Sclerosis Complex 2 Protein/*metabolism, Animals ; Computational Biology ; Cytochromes c/metabolism ; Disease Models, Animal ; Engineering ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Humans ; Immunoprecipitation ; In Situ Nick-End Labeling ; Induced Pluripotent Stem Cells/metabolism ; Male ; Mice, Transgenic ; Organoids/metabolism ; Phosphopyruvate Hydratase/genetics ; Rats ; Rats, Nude ; Reverse Transcriptase Polymerase Chain Reaction ; Sequence Analysis, RNA ; Tuberous Sclerosis Complex 2 Protein/genetics

المؤلفون: Kovalenko A; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Sanin A; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Kosmas K; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Zhang L; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Wang J; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Akl EW; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Giannikou K; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Probst CK; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Hougard TR; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Rue RW; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Lung Biology Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Krymskaya VP; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Lung Biology Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Asara JM; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts., Lam HC; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Kwiatkowski DJ; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Henske EP; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. cfilippakis@bwh.harvard.edu ehenske@bwh.harvard.edu., Filippakis H; Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. cfilippakis@bwh.harvard.edu ehenske@bwh.harvard.edu.

المصدر: Cancer research [Cancer Res] 2021 Apr 15; Vol. 81 (8), pp. 2086-2100. Date of Electronic Publication: 2021 Feb 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Diacylglycerol Kinase/*antagonists & inhibitors , Lung Neoplasms/*drug therapy , Lymphangioleiomyomatosis/*drug therapy , Pinocytosis/*drug effects , Ritanserin/*pharmacology , Tuberous Sclerosis/*drug therapy , Tuberous Sclerosis Complex 2 Protein/*deficiency, Angiolipoma/genetics ; Animals ; Autophagy/drug effects ; Cell Proliferation ; Chloroquine/pharmacology ; Diacylglycerol Kinase/genetics ; Diacylglycerol Kinase/metabolism ; Down-Regulation ; Drug Synergism ; Female ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Gene Expression ; Kidney Neoplasms/genetics ; Lung Neoplasms/etiology ; Lung Neoplasms/pathology ; Lymphangioleiomyomatosis/etiology ; Lymphangioleiomyomatosis/pathology ; Lysosomes/drug effects ; Lysosomes/metabolism ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mice ; Mice, Nude ; Nutrients/metabolism ; Phosphatidic Acids/metabolism ; Phospholipids/metabolism ; Pinocytosis/physiology ; Tuberous Sclerosis/complications

المؤلفون: Probst CK; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA., Montesi SB; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA., Medoff BD; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA., Shea BS; Division of Pulmonary and Critical Care Medicine, Brown University and Rhode Island Hospital, Providence, RI, USA., Knipe RS; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA.

المصدر: The European respiratory journal [Eur Respir J] 2020 Jul 16; Vol. 56 (1). Date of Electronic Publication: 2020 Jul 16 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE

مواضيع طبية MeSH: Capillary Permeability* , Idiopathic Pulmonary Fibrosis*/pathology, Fibrosis ; Humans ; Lung/pathology

المؤلفون: Santos DM; Division of Pulmonary and Critical Care Medicine, and., Pantano L; Harvard T. H. Chan School of Public Health, Boston, Massachusetts., Pronzati G; Division of Pulmonary and Critical Care Medicine, and., Grasberger P; Division of Pulmonary and Critical Care Medicine, and., Probst CK; Division of Pulmonary and Critical Care Medicine, and., Black KE; Division of Pulmonary and Critical Care Medicine, and., Spinney JJ; Division of Pulmonary and Critical Care Medicine, and., Hariri LP; Division of Pulmonary and Critical Care Medicine, and.; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Nichols R; Division of Pulmonary and Critical Care Medicine, and., Lin Y; Harvard T. H. Chan School of Public Health, Boston, Massachusetts., Bieler M; Computational Chemistry., Seither P; Business Development and Licensing., Nicklin P; Research Beyond Borders, and., Wyatt D; Biotherapeutics Discovery, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß, Germany., Tager AM; Division of Pulmonary and Critical Care Medicine, and., Medoff BD; Division of Pulmonary and Critical Care Medicine, and.

المصدر: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2020 Apr; Vol. 62 (4), pp. 479-492.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*antagonists & inhibitors , Cell Cycle Proteins/*antagonists & inhibitors , Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology , Pulmonary Fibrosis/*drug therapy, Acyl Coenzyme A/metabolism ; Animals ; Biomarkers/metabolism ; Bleomycin/pharmacology ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Cytoplasm/drug effects ; Cytoplasm/metabolism ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Humans ; Mevalonic Acid/metabolism ; Mice ; Phosphoproteins/metabolism ; Pulmonary Fibrosis/metabolism ; Signal Transduction/drug effects ; Simvastatin/pharmacology ; Small Molecule Libraries/pharmacology ; YAP-Signaling Proteins

المؤلفون: Rodríguez-Rodríguez A; The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States., Shuvaev S; The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States., Rotile N; The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States., Jones CM; The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States., Probst CK; Division of Pulmonary and Critical Care Medicine and the Center for Immunology and Inflammatory Diseases , Massachusetts General Hospital , Boston , Massachusetts 02114 , United States., Dos Santos Ferreira D; The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States., Graham-O Regan K; The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States., Boros E; The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States., Knipe RS; Division of Pulmonary and Critical Care Medicine and the Center for Immunology and Inflammatory Diseases , Massachusetts General Hospital , Boston , Massachusetts 02114 , United States., Griffith JW; Division of Pulmonary and Critical Care Medicine and the Center for Immunology and Inflammatory Diseases , Massachusetts General Hospital , Boston , Massachusetts 02114 , United States., Tager AM; Division of Pulmonary and Critical Care Medicine and the Center for Immunology and Inflammatory Diseases , Massachusetts General Hospital , Boston , Massachusetts 02114 , United States., Bogdanov A Jr; Department of Radiology , University of Massachusetts Medical School , Worcester , Massachusetts 01655 , United States., Caravan P; The Institute for Innovation in Imaging , A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School , Charlestown , Massachusetts 02129 , United States.

المصدر: ACS sensors [ACS Sens] 2019 Sep 27; Vol. 4 (9), pp. 2412-2419. Date of Electronic Publication: 2019 Aug 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101669031 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-3694 (Electronic) Linking ISSN: 23793694 NLM ISO Abbreviation: ACS Sens Subsets: MEDLINE

مواضيع طبية MeSH: Contrast Media/*metabolism , Magnetic Resonance Imaging/*methods , Peroxidases/*metabolism , Pneumonia/*diagnostic imaging, Animals ; Contrast Media/chemistry ; Mice ; Serotonin/chemistry

المؤلفون: Paul MJ; Department of Psychology, University at Buffalo, SUNY, Buffalo, NY 14260, USA; Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Amherst, MA 01003, USA. Electronic address: mjpaul@buffalo.edu., Probst CK; Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Amherst, MA 01003, USA., Brown LM; Department of Psychology, University at Buffalo, SUNY, Buffalo, NY 14260, USA., de Vries GJ; Center for Neuroendocrine Studies, University of Massachusetts, Amherst, Amherst, MA 01003, USA; Neuroscience Institute, Georgia State University, Atlanta, GA 30302, USA.

المصدر: Current biology : CB [Curr Biol] 2018 Apr 02; Vol. 28 (7), pp. 1116-1123.e2. Date of Electronic Publication: 2018 Mar 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: England NLM ID: 9107782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0445 (Electronic) Linking ISSN: 09609822 NLM ISO Abbreviation: Curr Biol Subsets: MEDLINE

مواضيع طبية MeSH: Breeding* , Seasons* , Social Behavior*, Aggression/*physiology , Gonadal Steroid Hormones/*metabolism , Sexual Maturation/*physiology, Animals ; Female ; Male ; Phodopus ; Photoperiod ; Reproduction