المؤلفون: Fulcher JM; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99354, USA., Swensen AC; Integrative Omics, Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USA., Chen YC; Department of Surgery, BC Children's Hospital Research Institute and University of British Columbia, Vancouver, British Columbia, V5Z 4H4, Canada., Verchere CB; Department of Surgery, BC Children's Hospital Research Institute and University of British Columbia, Vancouver, British Columbia, V5Z 4H4, Canada.; Department of Pathology and Laboratory Medicine, BC Children's Hospital Research Institute and University of British Columbia, Vancouver, British Columbia, V5Z 4H4, Canada., Petyuk VA; Integrative Omics, Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USA., Qian WJ; Integrative Omics, Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USA.

المصدر: Endocrinology [Endocrinology] 2023 Nov 02; Vol. 164 (12).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

مواضيع طبية MeSH: Insulin-Secreting Cells*/metabolism , Islets of Langerhans*/metabolism, Mice ; Animals ; Proinsulin/genetics ; Proinsulin/metabolism ; Carboxypeptidase H/genetics ; Carboxypeptidase H/metabolism ; Proteomics ; Proprotein Convertase 2/genetics ; Proprotein Convertase 2/metabolism ; Mice, Knockout

المؤلفون: Márquez-Nogueras KM; Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, Illinois., Vuchkovska V; Graduate School, Loyola University Chicago, Maywood, Illinois., DiNello E; Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, Illinois., Osorio-Valencia S; Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, Illinois., Kuo IY; Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, Illinois.

المصدر: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2022 Aug 01; Vol. 323 (2), pp. C333-C346. Date of Electronic Publication: 2022 Jun 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Calcium*/metabolism , Muscle Development*/physiology , Proprotein Convertase 2*/metabolism , TRPP Cation Channels*/genetics , TRPP Cation Channels*/metabolism, Animals ; Calcium Channels/metabolism ; Mice ; Mice, Knockout ; Muscle, Skeletal ; Signal Transduction

المؤلفون: Basu J; Department of Life Sciences, Presidency University, Kolkata, India., Mukherjee R; Department of Life Sciences, Presidency University, Kolkata, India., Sahu P; Department of Gynecology and Obstetrics, Institute of Post Graduate Medical Education and Research, Kolkata, India., Datta C; Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, India., Chowdhury S; Department of Endocrinology, Institute of Post Graduate Medical Education and Research, Kolkata, India., Mandal D; Department of Gynecology and Obstetrics, Institute of Post Graduate Medical Education and Research, Kolkata, India., Ghosh A; Department of Life Sciences, Presidency University, Kolkata, India.

المصدر: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2024; Vol. 43 (3), pp. 185-202. Date of Electronic Publication: 2023 Aug 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 100892832 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2335 (Electronic) Linking ISSN: 15257770 NLM ISO Abbreviation: Nucleosides Nucleotides Nucleic Acids Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes, Gestational*/genetics , Diabetes Mellitus, Type 2*/genetics, Humans ; Female ; Pregnancy ; Proinsulin/genetics ; Proinsulin/metabolism ; C-Peptide/genetics ; Polymorphism, Single Nucleotide ; Genetic Predisposition to Disease ; Transcription Factor 7-Like 2 Protein/genetics ; Proprotein Convertase 2/genetics

المؤلفون: Dowsett GKC; MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. Electronic address: Dowsett.gkcd2@cam.ac.uk., Lam BYH; MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. Electronic address: Lam.yhbl2@cam.ac.uk., Tadross JA; MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK; Department of Pathology, University of Cambridge, Cambridge, CB2 1QP, UK. Electronic address: Tadross.jt636@medschl.cam.ac.uk., Cimino I; MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. Electronic address: ic326@medschl.cam.ac.uk., Rimmington D; MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. Electronic address: dy222@cam.ac.uk., Coll AP; MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. Electronic address: apc36@cam.ac.uk., Polex-Wolf J; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark. Electronic address: jhpw@novonordisk.com., Knudsen LB; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark. Electronic address: lbkn@novonordisk.com., Pyke C; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark. Electronic address: pyke@novonordisk.com., Yeo GSH; MRC Metabolic Diseases Unit, University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. Electronic address: gshy2@cam.ac.uk.

المصدر: Molecular metabolism [Mol Metab] 2021 Nov; Vol. 53, pp. 101240. Date of Electronic Publication: 2021 May 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Eating* , Fasting*, Proprotein Convertase 1/*genetics , Proprotein Convertase 2/*genetics , Rhombencephalon/*metabolism, Animals ; Area Postrema/metabolism ; Feeding Behavior ; Mice ; Mice, Inbred C57BL ; Neurons/metabolism ; Proprotein Convertase 1/metabolism ; Proprotein Convertase 2/metabolism ; Sequence Analysis, RNA ; Solitary Nucleus/metabolism

المؤلفون: Ramzy A; Laboratory of Molecular and Cellular Medicine, Department of Cellular and Physiological Sciences, Life Sciences Institute, The University of British Columbia, Vancouver, British Columbia, Canada., Asadi A; Laboratory of Molecular and Cellular Medicine, Department of Cellular and Physiological Sciences, Life Sciences Institute, The University of British Columbia, Vancouver, British Columbia, Canada., Kieffer TJ; Laboratory of Molecular and Cellular Medicine, Department of Cellular and Physiological Sciences, Life Sciences Institute, The University of British Columbia, Vancouver, British Columbia, Canada tim.kieffer@ubc.ca.; Department of Surgery, The University of British Columbia, Vancouver, British Columbia, Canada.

المصدر: Diabetes [Diabetes] 2020 Jul; Vol. 69 (7), pp. 1451-1462. Date of Electronic Publication: 2020 Apr 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Insulin-Secreting Cells/*metabolism , Proinsulin/*metabolism , Proprotein Convertase 1/*physiology , Proprotein Convertase 2/*physiology, Animals ; Diabetes Mellitus, Type 2/metabolism ; Humans ; Immunohistochemistry ; Mice ; Mice, Inbred C57BL ; Proprotein Convertase 1/analysis ; Proprotein Convertase 2/analysis ; Proprotein Convertase 2/metabolism

المؤلفون: Sharker MR; Department of Fisheries Science, College of Fisheries and Ocean Sciences, Chonnam National University, Jeonnam, Republic of Korea., Nou IS; Department of Horticulture, College of Life Science and Natural Resources, Sunchon National University, Jeollanam-do, Republic of Korea., Kho KH; Department of Fisheries Science, College of Fisheries and Ocean Sciences, Chonnam National University, Jeonnam, Republic of Korea.

المصدر: PloS one [PLoS One] 2020 Apr 09; Vol. 15 (4), pp. e0231353. Date of Electronic Publication: 2020 Apr 09 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Gastropoda/*enzymology , Proprotein Convertase 2/*metabolism, Amino Acid Sequence ; Animals ; Cloning, Molecular ; Female ; Ganglia/metabolism ; Ganglia/pathology ; Gonads/metabolism ; In Situ Hybridization ; Phylogeny ; Proprotein Convertase 2/classification ; Proprotein Convertase 2/genetics ; RNA, Messenger/metabolism ; Sequence Alignment ; Temperature

المؤلفون: Coppola I; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium., Brouwers B; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium., Walker L; Division of Diabetes, Endocrinology & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 3.016 AV Hill Building, Manchester M13 9PT, United Kingdom., Alar C; Laboratory of Multi-omic Integrative Bioinformatics, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium., Meulemans S; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium., White A; Division of Diabetes, Endocrinology & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 3.016 AV Hill Building, Manchester M13 9PT, United Kingdom. Electronic address: anne.white@manchester.ac.uk., Ramos-Molina B; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium; Obesity and Metabolism Research Laboratory, Biomedical Research Institute of Murcia (IMIB), Murcia 30120, Spain. Electronic address: bruno.ramos@imib.es., Creemers JWM; Laboratory for Biochemical Neuroendocrinology, Department of Human Genetics, KU Leuven, Leuven 3000, Belgium. Electronic address: john.creemers@kuleuven.be.

المصدر: Molecular metabolism [Mol Metab] 2022 Dec; Vol. 66, pp. 101627. Date of Electronic Publication: 2022 Oct 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2* , Feeding Behavior*/physiology , Furin*/genetics , Furin*/metabolism , Hypothalamus*/metabolism , Pro-Opiomelanocortin*/genetics , Pro-Opiomelanocortin*/metabolism, Animals ; Humans ; Mice ; alpha-MSH/metabolism ; Body Weight ; Diet, High-Fat/adverse effects ; Glucose ; HEK293 Cells ; Proprotein Convertase 1/genetics ; Proprotein Convertase 1/metabolism ; Proprotein Convertase 2/genetics ; Proprotein Convertase 2/metabolism ; Proprotein Convertases/genetics ; Proprotein Convertases/metabolism ; RNA, Messenger/metabolism ; Subtilisins/genetics ; Subtilisins/metabolism

المؤلفون: Chang SY; Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota., DeVera C; Department of Neurobiology, Neuroscience Institute, Morehouse School of Medicine, Atlanta, Georgia., Yang Z; Department of Neurobiology, Neuroscience Institute, Morehouse School of Medicine, Atlanta, Georgia., Yang T; Department of Neurobiology, Neuroscience Institute, Morehouse School of Medicine, Atlanta, Georgia., Song L; Department of Neurobiology, Neuroscience Institute, Morehouse School of Medicine, Atlanta, Georgia., McDowell A; Department of Neurobiology, Neuroscience Institute, Morehouse School of Medicine, Atlanta, Georgia., Xiong ZG; Department of Neurobiology, Neuroscience Institute, Morehouse School of Medicine, Atlanta, Georgia., Simon R; Department of Neurobiology, Neuroscience Institute, Morehouse School of Medicine, Atlanta, Georgia., Zhou A; Department of Neurobiology, Neuroscience Institute, Morehouse School of Medicine, Atlanta, Georgia.

المصدر: Hippocampus [Hippocampus] 2020 Jul; Vol. 30 (7), pp. 715-723. Date of Electronic Publication: 2020 Feb 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9108167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1063 (Electronic) Linking ISSN: 10509631 NLM ISO Abbreviation: Hippocampus Subsets: MEDLINE

مواضيع طبية MeSH: Excitatory Postsynaptic Potentials/*physiology , Hippocampus/*enzymology , Maze Learning/*physiology , Proprotein Convertase 2/*deficiency, Animals ; Brain Ischemia/enzymology ; Brain Ischemia/genetics ; Female ; Male ; Mice ; Mice, Knockout ; Organ Culture Techniques ; Proprotein Convertase 2/genetics

المؤلفون: Sarwade RD; National Centre of Cell Science, Ganeshkhind, Pune, 411007, India; Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India., Khalique A; National Centre of Cell Science, Ganeshkhind, Pune, 411007, India; Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India., Kulkarni SD; National Centre of Cell Science, Ganeshkhind, Pune, 411007, India; Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India., Pandey PR; National Centre of Cell Science, Ganeshkhind, Pune, 411007, India; Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India., Gaikwad N; National Centre of Cell Science, Ganeshkhind, Pune, 411007, India; Savitribai Phule Pune University, Ganeshkhind, Pune, 411007, India., Seshadri V; National Centre of Cell Science, Ganeshkhind, Pune, 411007, India. Electronic address: seshadriv@nccs.res.in.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Jun 04; Vol. 526 (3), pp. 618-625. Date of Electronic Publication: 2020 Apr 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Protein Biosynthesis*, Insulin/*metabolism , Poly(A)-Binding Proteins/*metabolism , Proprotein Convertase 1/*metabolism , Proprotein Convertase 2/*metabolism , Protein Disulfide-Isomerases/*metabolism, 5' Untranslated Regions ; Animals ; Cell Line ; Cytoplasmic Granules/genetics ; Cytoplasmic Granules/metabolism ; Insulin/genetics ; Mice ; Poly(A)-Binding Proteins/genetics ; Proprotein Convertase 1/genetics ; Proprotein Convertase 2/genetics ; Protein Disulfide-Isomerases/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

المؤلفون: Callon D; Cardiovir EA-4684, Faculty of Medicine, University of Reims Champagne Ardennes, 51 Rue Cognacq Jay, 51097 Reims, France.; Pathology Department, Academic Hospital of Reims, Robert Debré, 51100 Reims, France., Guedra A; Cardiovir EA-4684, Faculty of Medicine, University of Reims Champagne Ardennes, 51 Rue Cognacq Jay, 51097 Reims, France.; Pathology Department, Academic Hospital of Reims, Robert Debré, 51100 Reims, France., Lebreil AL; Cardiovir EA-4684, Faculty of Medicine, University of Reims Champagne Ardennes, 51 Rue Cognacq Jay, 51097 Reims, France., Heng L; Cardiovir EA-4684, Faculty of Medicine, University of Reims Champagne Ardennes, 51 Rue Cognacq Jay, 51097 Reims, France., Bouland N; Pathology Department, Academic Hospital of Reims, Robert Debré, 51100 Reims, France., Fornès P; Cardiovir EA-4684, Faculty of Medicine, University of Reims Champagne Ardennes, 51 Rue Cognacq Jay, 51097 Reims, France.; Pathology Department, Academic Hospital of Reims, Robert Debré, 51100 Reims, France., Berri F; Cardiovir EA-4684, Faculty of Medicine, University of Reims Champagne Ardennes, 51 Rue Cognacq Jay, 51097 Reims, France., Andreoletti L; Cardiovir EA-4684, Faculty of Medicine, University of Reims Champagne Ardennes, 51 Rue Cognacq Jay, 51097 Reims, France.; Virology Department, Academic Hospital of Reims, Robert Debré, 51100 Reims, France.

المصدر: Viruses [Viruses] 2022 Dec 13; Vol. 14 (12). Date of Electronic Publication: 2022 Dec 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Insulin-Secreting Cells* , Diabetes Mellitus, Type 1* , Coxsackievirus Infections*, Mice ; Humans ; Animals ; Insulin/metabolism ; RNA/metabolism ; Enterovirus B, Human/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Virus Replication ; Proprotein Convertase 2/metabolism