المؤلفون: Golino P; Department of Internal Medicine, University of Naples, Italy., Ambrosio G, Villari B, Ragni M, Focaccio A, Pace L, de Clerk F, Condorelli M, Chiariello M

المصدر: Journal of the American College of Cardiology [J Am Coll Cardiol] 1993 Feb; Vol. 21 (2), pp. 493-501.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print Cited Medium: Print ISSN: 0735-1097 (Print) Linking ISSN: 07351097 NLM ISO Abbreviation: J Am Coll Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Myocardial Infarction/*physiopathology , Myocardial Reperfusion Injury/*prevention & control , Prostaglandin Endoperoxides/*physiology , Receptors, Thromboxane/*antagonists & inhibitors , Thromboxane-A Synthase/*antagonists & inhibitors, Animals ; Aspirin/pharmacology ; Bridged Bicyclo Compounds, Heterocyclic ; Fatty Acids, Unsaturated ; Female ; Hydrazines/pharmacology ; Imidazoles/pharmacology ; Male ; Myocardial Infarction/prevention & control ; Myocardial Reperfusion Injury/physiopathology ; Pentanoic Acids/pharmacology ; Platelet Aggregation/drug effects ; Prostaglandin Endoperoxides, Synthetic/pharmacology ; Pyridines/pharmacology ; Rabbits

المؤلفون: Murray R; Division of Clinical Pharmacology, Vanderbilt University, Nashville, Tennessee 37232., Shipp E, FitzGerald GA

المصدر: The Journal of biological chemistry [J Biol Chem] 1990 Dec 15; Vol. 265 (35), pp. 21670-5.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Platelet Activation*, Adenylyl Cyclases/*blood , Prostaglandin Endoperoxides/*physiology , Receptors, Prostaglandin/*physiology , Thromboxane A2/*physiology , Type C Phospholipases/*blood, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ; Cyclic AMP/blood ; Down-Regulation ; Enzyme Activation/drug effects ; Humans ; Iloprost/pharmacology ; In Vitro Techniques ; Platelet Activating Factor/pharmacology ; Platelet Aggregation/drug effects ; Prostaglandin Endoperoxides, Synthetic/pharmacology ; Protein Kinase C/physiology ; Receptors, Thromboxane ; Thrombin/pharmacology

المؤلفون: de Chaffoy de Courcelles D; Department of Biochemistry, Janssen Research Foundation, Beerse, Belgium., De Clerck F

المصدر: European journal of pharmacology [Eur J Pharmacol] 1990 Mar 13; Vol. 188 (2-3), pp. 161-9.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print Cited Medium: Print ISSN: 0014-2999 (Print) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Blood Platelets/*metabolism , Inositol Phosphates/*blood , Prostaglandin Endoperoxides/*blood , Serotonin/*blood , Thromboxane A2/*blood , Thromboxane-A Synthase/*antagonists & inhibitors, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ; Blood Platelets/drug effects ; Collagen/pharmacology ; Humans ; In Vitro Techniques ; Indomethacin/pharmacology ; Methacrylates/pharmacology ; Platelet Activating Factor/pharmacology ; Prostaglandin Endoperoxides, Synthetic/pharmacology ; Sulfonamides/pharmacology

المؤلفون: Aksoy MO; Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140., Harakal C, Smith JB, Stewart GJ, Zerweck CR

المصدر: British journal of pharmacology [Br J Pharmacol] 1990 Mar; Vol. 99 (3), pp. 461-6.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print Cited Medium: Print ISSN: 0007-1188 (Print) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Bradykinin/*pharmacology , Muscle, Smooth, Vascular/*drug effects , Prostaglandin Endoperoxides/*metabolism , Receptors, Prostaglandin/*drug effects , Thromboxanes/*metabolism, Animals ; Bridged Bicyclo Compounds, Heterocyclic ; Dogs ; Endothelium, Vascular/physiology ; Fatty Acids, Unsaturated ; Female ; Hydrazines/pharmacology ; Imidazoles/pharmacology ; In Vitro Techniques ; Muscle Contraction/drug effects ; Prostaglandin Endoperoxides, Synthetic/metabolism ; Prostaglandin H2 ; Prostaglandin-Endoperoxide Synthases/metabolism ; Prostaglandins H/metabolism ; Pyridines/pharmacology ; Sulfonamides/pharmacology ; Thromboxane-A Synthase/antagonists & inhibitors ; Veins/drug effects

المؤلفون: Nicolaou KC, Gasic GP, Barnette WE

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 1978 May; Vol. 17 (5), pp. 293-312.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print Cited Medium: Print ISSN: 1433-7851 (Print) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

مواضيع طبية MeSH: Epoprostenol*/biosynthesis , Epoprostenol*/physiology , Prostaglandin Endoperoxides*/physiology , Prostaglandins*/physiology , Thromboxanes*/biosynthesis , Thromboxanes*/physiology, Animals ; Cats ; Prostaglandin Endoperoxides, Synthetic/chemical synthesis ; Prostaglandin Endoperoxides, Synthetic/pharmacology

المؤلفون: Magri DC; Department of Chemistry, The University of Western Ontario, London, Ontario, Canada N6A 5B7., Workentin MS

المصدر: Organic & biomolecular chemistry [Org Biomol Chem] 2008 Sep 21; Vol. 6 (18), pp. 3354-61. Date of Electronic Publication: 2008 Jul 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Electrons*, Bridged Bicyclo Compounds, Heterocyclic/*chemistry , Prostaglandin Endoperoxides/*chemical synthesis, Anions/chemistry ; Kinetics ; Models, Biological ; Molecular Structure ; Oxidation-Reduction ; Prostaglandin Endoperoxides/chemistry ; Thermodynamics

المؤلفون: Ruan KH; Vascular Biology Research Center, Division of Hematology, Department of Internal Medicine, The University of Texas Health Science Center, Houston, 77030, USA. kruan@uth.tmc.edu, Wu J, Wang LH

المصدر: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2005 Dec 15; Vol. 444 (2), pp. 165-73. Date of Electronic Publication: 2005 Nov 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0003-9861 (Print) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

مواضيع طبية MeSH: Models, Chemical* , Models, Molecular*, Biomimetic Materials/*chemistry , Magnetic Resonance Spectroscopy/*methods , Prostaglandin Endoperoxides, Synthetic/*chemistry , Prostaglandin H2/*analogs & derivatives , Thromboxane-A Synthase/*chemistry, Binding Sites ; Biomimetic Materials/analysis ; Computer Simulation ; Prostaglandin Endoperoxides, Synthetic/analysis ; Prostaglandin-Endoperoxide Synthases/analysis ; Prostaglandin-Endoperoxide Synthases/chemistry ; Protein Binding ; Protein Conformation ; Protein Engineering ; Recombinant Proteins/analysis ; Recombinant Proteins/chemistry ; Solutions ; Substrate Specificity ; Thromboxane-A Synthase/analysis ; Thromboxane-A Synthase/genetics

المؤلفون: So SP; Vascular Biology Research Center and Division of Hematology, the Department of Internal Medicine, the University of Texas Health Science Center, Houston, Texas 77030, USA., Li D, Ruan KH

المصدر: The Journal of biological chemistry [J Biol Chem] 2000 Dec 29; Vol. 275 (52), pp. 40679-85.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/*chemistry , Prostaglandin Endoperoxides, Synthetic/*chemistry , Thromboxane-A Synthase/*chemistry, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/metabolism ; Binding Sites ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Prostaglandin Endoperoxides, Synthetic/metabolism ; Structure-Activity Relationship ; Thromboxane-A Synthase/physiology

المؤلفون: Blaise GA; Department of Anesthesia, University of Montreal, Quebec, Canada., Parent M, Laurin S, Omri A, Reader TA, Moutquin JM

المصدر: Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 1994 Apr; Vol. 8 (2), pp. 175-81.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 9110208 Publication Model: Print Cited Medium: Print ISSN: 1053-0770 (Print) Linking ISSN: 10530770 NLM ISO Abbreviation: J Cardiothorac Vasc Anesth Subsets: MEDLINE

مواضيع طبية MeSH: Blood Platelets/*drug effects , Coronary Vessels/*drug effects , Halothane/*pharmacology , Isoflurane/*pharmacology , Platelet Activation/*drug effects , Platelet Aggregation/*drug effects , Prostaglandin Endoperoxides, Synthetic/*pharmacology , Thromboxane A2/*analogs & derivatives , Vasoconstrictor Agents/*pharmacology , Vasomotor System/*drug effects, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ; Animals ; Blood Platelets/metabolism ; Coronary Vasospasm/physiopathology ; Dogs ; Dose-Response Relationship, Drug ; Female ; Halothane/administration & dosage ; Humans ; Isoflurane/administration & dosage ; Male ; Muscle, Smooth, Vascular/drug effects ; Prostaglandin Endoperoxides, Synthetic/administration & dosage ; Prostaglandin Endoperoxides, Synthetic/metabolism ; Serotonin/analysis ; Serotonin/metabolism ; Thromboxane A2/administration & dosage ; Thromboxane A2/metabolism ; Thromboxane A2/pharmacology ; Thromboxane B2/analysis ; Thromboxane B2/metabolism ; Vasoconstriction ; Vasoconstrictor Agents/administration & dosage ; Vasoconstrictor Agents/metabolism

المؤلفون: Komiotis D; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois, Chicago 60612., Lim CT, Dieter JP, Le Breton GC, Venton DL

المصدر: Journal of medicinal chemistry [J Med Chem] 1992 Aug 07; Vol. 35 (16), pp. 3033-9.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Platelet Aggregation Inhibitors/*pharmacology , Prostaglandin Endoperoxides, Synthetic/*pharmacology , Prostaglandins H/*pharmacology, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid ; Adenosine Diphosphate/antagonists & inhibitors ; Adenosine Diphosphate/pharmacology ; Cells, Cultured ; Humans ; Platelet Aggregation Inhibitors/chemistry ; Prostaglandin Endoperoxides, Synthetic/antagonists & inhibitors ; Prostaglandin Endoperoxides, Synthetic/chemistry ; Prostaglandin H2 ; Prostaglandins H/chemistry ; Structure-Activity Relationship