المؤلفون: Oliva MA, Prota AE, Rodríguez-Salarichs J, Gu W, Bennani YL, Jimenez-Barbero J, Bargsten K, Canales A, Steinmetz MO, Diaz JF

مصطلحات موضوعية: tubulin, noscapine, STD-NMR

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______2659::70cbf6f88aab9ede6980ce3afa96a271
https://zenodo.org/record/4309540

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المؤلفون: Trigili, C, Barasoain, I, Sánchez-Murcia, PA, Bargsten, K, Redondo-Horcajo, M, Nogales, A, Gardner, NM, Meyer, A, Naylor, GJ, Gómez-Rubio, E, Gago, F, Steinmetz, MO, Paterson, I, Prota, AE, Díaz, JF

مصطلحات موضوعية: Biomedical, Basic Science, 5.1 Pharmaceuticals, 0601 Biochemistry and Cell Biology, 3. Good health, Cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f3c59819e8c2c0217878f4d38d20563

المؤلفون: Grégory Menchon, Lucia Altucci, Giulia Chemi, Simone Brogi, Michel O. Steinmetz, Angela Nebbioso, Natacha Olieric, Daniela M. Zisterer, Francisco de Asís Balaguer, Stefania Butini, Rebecca Amet, Cristina Ulivieri, Alessandro Grillo, Jeff O'Sullivan, Isabel Barasoain, Margherita Brindisi, J. Fernando Díaz, Ettore Novellino, Roberta Spaccapelo, Daniel Lucena-Agell, Ludovica Lopresti, Andrea E. Prota, Sandra Gemma, Mariarosaria Conte, Stefania Magnano, Cosima T. Baldari, Gloria Alfano, Giuseppe Campiani, Paula Kinsella, Tuhina Khan, Lucia Morbidelli, Ola Ibrahim

المساهمون: Brindisi, M, Ulivieri, C, Alfano, G, Gemma, S, de Asís Balaguer, F, Khan, T, Grillo, A, Chemi, G, Menchon, G, Prota, Ae, Olieric, N, Lucena-Agell, D, Barasoain, I, Diaz, Jf, Nebbioso, A, Conte, M, Lopresti, L, Magnano, S, Amet, R, Kinsella, P, Zisterer, Dm, Ibrahim, O, O'Sullivan, J, Morbidelli, L, Spaccapelo, R, Baldari, C, Butini, S, Novellino, E, Campiani, G, Altucci, L, Steinmetz, Mo, Brogi, S., Swiss National Science Foundation, Ministerio de Economía y Competitividad (España), European Commission, Ministero dell'Istruzione, dell'Università e della Ricerca, Brindisi, Margherita, Ulivieri, Cristina, Alfano, Gloria, Gemma, Sandra, de Asís Balaguer, Francisco, Khan, Tuhina, Grillo, Alessandro, Chemi, Giulia, Menchon, Grégory, Prota, Andrea E, Olieric, Natacha, Lucena-Agell, Daniel, Barasoain, Isabel, Diaz, J Fernando, Nebbioso, Angela, Conte, Mariarosaria, Lopresti, Ludovica, Magnano, Stefania, Amet, Rebecca, Kinsella, Paula, Zisterer, Daniela M, Ibrahim, Ola, O'Sullivan, Jeff, Morbidelli, Lucia, Spaccapelo, Roberta, Baldari, Cosima, Butini, Stefania, Novellino, Ettore, Campiani, Giuseppe, Altucci, Lucia, Steinmetz, Michel O

المصدر: European Journal of Medicinal Chemistry
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Antitumor agents, Apoptosis, Microtubule-targeting agent, Molecular modeling, Tubulin, X-ray crystallography, Antineoplastic Agents, Cell Cycle, Cell Differentiation, Cell Line, Tumor, Drug Resistance, Multiple, Drug Screening Assays, Antitumor, Humans, Microtubules, Molecular Structure, Oxazepines, Structure-Activity Relationship, Pharmacology, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Cellular differentiation, Drug Resistance, Drug Screening Assays, 01 natural sciences, Cancer, epigenetics, Drug Discovery, 0303 health sciences, Tumor, Chemistry, General Medicine, Cell cycle, 3. Good health, medicine.symptom, Multiple, Computational biology, Cell Line, 03 medical and health sciences, medicine, Structure–activity relationship, Mode of action, 030304 developmental biology, 010405 organic chemistry, Antitumor agent, Apoptosi, Antitumor, 0104 chemical sciences, Multiple drug resistance, Mechanism of action, Cell culture, Cancer cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac07af3e053396026a7fa9fca0f7aa6
http://hdl.handle.net/11391/1447652

المؤلفون: Steinmetz MO; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland; University of Basel, Biozentrum, 4056 Basel, Switzerland. Electronic address: michel.steinmetz@psi.ch., Prota AE; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland. Electronic address: andrea.prota@psi.ch.

المصدر: Current opinion in structural biology [Curr Opin Struct Biol] 2024 Aug; Vol. 87, pp. 102845. Date of Electronic Publication: 2024 May 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9107784 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-033X (Electronic) Linking ISSN: 0959440X NLM ISO Abbreviation: Curr Opin Struct Biol Subsets: MEDLINE

مواضيع طبية MeSH: Microtubules*/metabolism , Microtubules*/chemistry , Microtubules*/drug effects , Tubulin*/chemistry , Tubulin*/metabolism , Tubulin Modulators*/chemistry , Tubulin Modulators*/pharmacology, Humans ; Drug Discovery/methods ; Drug Design ; Animals ; Structure-Activity Relationship ; Models, Molecular

المؤلفون: Abel AC; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, Villigen, Switzerland; Biozentrum, University of Basel, Basel, Switzerland., Mühlethaler T; Biozentrum, University of Basel, Basel, Switzerland., Dessin C; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Schachtsiek T; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Sammet B; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Sharpe T; Biozentrum, University of Basel, Basel, Switzerland., Steinmetz MO; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, Villigen, Switzerland; Biozentrum, University of Basel, Basel, Switzerland., Sewald N; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany. Electronic address: norbert.sewald@uni-bielefeld.de., Prota AE; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, Villigen, Switzerland. Electronic address: andrea.prota@psi.ch.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107363. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Tubulin*/chemistry , Tubulin*/metabolism , Maytansine*/chemistry , Maytansine*/analogs & derivatives, Humans ; Crystallography, X-Ray ; Binding Sites ; Microtubules/metabolism ; Microtubules/chemistry ; Vinca Alkaloids/chemistry ; Vinca Alkaloids/metabolism