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1دورية أكاديمية
المؤلفون: Rolando Sánchez Artigas, María Teresa Díaz Armas, Raisa Rodríguez Duque, Pedro Enrique Miguel Soca
المصدر: Medisur, Vol 19, Iss 6, Pp 1005-1014 (2021)
مصطلحات موضوعية: edición génica, sistemas crispr-cas, proteína 9 asociada a crispr, Medicine (General), R5-920, Public aspects of medicine, RA1-1270
وصف الملف: electronic resource
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المؤلفون: Dorsant Ardón, Valérie
المساهمون: Salguero López, Gustavo Andrés, Dueñas Gómez, Zulma Janeth, Unidad de Terapias Avanzadas – Instituto Distrital de Ciencia Biotecnología e Innovación (IDCBIS)
المصدر: Repositorio UN
Universidad Nacional de Colombia
instacron:Universidad Nacional de Colombiaمصطلحات موضوعية: Gene edition, Mucopolisacaridosis tipo IV A, Mucopolysaccharidoses type VI A, Mutagenicity Tests, Edición génica, Enfermedad de Morquio, Mesenchymal stromal cells, Mesenchymal Stem Cells, Células Madre Mesenquimatosas, Células estromales mesenquimales, Proteína 9 asociada a CRISPR, CRISPR-Associated Protein 9, 576 - Genética y evolución [570 - Biología], Morquio’s disease, Pruebas de Mutagenicidad
وصف الملف: 71 páginas; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e4fed601afe7916a4bc1e8bf7293198e
https://repositorio.unal.edu.co/ -
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المؤلفون: Jose L. Saenz-Garcia, Beatriz S. Borges, Normanda Souza-Melo, Luiz V. Machado, Juliana S. Miranda, Lisandro Alfonso Pacheco-Lugo, Nilmar S. Moretti, Richard Wheleer, Lia C. Soares Medeiros, Wanderson D. DaRocha
المصدر: Repositório Institucional da FIOCRUZ (ARCA)
Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Frontiers in Cellular and Infection Microbiologyمصطلحات موضوعية: Microbiology (medical), Trypanosoma cruzi, Trypanosoma brucei brucei, Immunology, Protozoan Proteins, Motilidade, Trypanosoma cruzi (T. cruzi), Microbiology, Cellular and Infection Microbiology, metacyclogenesis, CRISPR-Associated Protein 9, parasitic diseases, Animals, Proteína 9 Asociada a CRISPR, Proteína 9 Associada à CRISPR, Chagas Disease, Protéine-9 associée à CRISPR, Original Research, trypanin, Flagellum, Flagelos, SaCas9, QR1-502, Metaciclogênese, Infectious Diseases, motility, Flagella, Flagelles, detached flagellum, CRISPR-Cas9, Trypanin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601eb87801cd2b72a4cb473081f64dcc
https://www.arca.fiocruz.br/handle/icict/51869 -
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المؤلفون: Miguel López, Gloria Perazzoli, Consolación Melguizo, Fernando Setien, Raúl Ortiz, Rosa Hernández, María Berdasco, Manel Esteller, Cristina Jiménez-Luna, Jose Prados
المساهمون: [Hernández,R, Jiménez-Luna,C, Ortiz,R, Perazzoli,G, Prados,J, Melguizo,C] Center of Biomedical Research (CIBM), Institute of Biopathology and Regenerative Medicine (IBIMER), University of Granada, Granada, Spain, Melguizo,C] Biosanitary Institute of Granada (ibs.GRANADA), SAS-University of Granada, Granada, Spain. [Ortiz,R, Melguizo,C] Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, Granada, Spain. [Setién,F, López,M, Esteller,M, Berdasco,M] Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, L’Hospitalet de Llobregat, Barcelona, Spain, [Setién,F, Esteller,M] Cancer Epigenetics Group, Cancer and Leukemia Epigenetics and Biology Program (PEBCL), Josep Carreras Leukemia Research Institute (IJC), Barcelona, Spain. [López,M, Berdasco,M] Epigenetic Therapies Group, Experimental and Clinical Hematology Program (PHEC), Josep Carreras Leukemia Research Institute, Barcelona, Spain, Fundació La Marató TV3 (111430/31) and by the financial support from the CTS-107 Group from Junta de Andalucía.
المصدر: Biology
Volume 10
Issue 8
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Biology, Vol 10, Iss 802, p 802 (2021)
Dipòsit Digital de la UB
Universidad de Barcelonaمصطلحات موضوعية: Epigenetic changes, QH301-705.5, Adipose tissue, Células madre mesenquimatosas, CRISPR/ dCas9, Hoxa-5, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Cell therapy, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Malalties del sistema nerviós, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Essential [Medical Subject Headings], Neurosphere, Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Intercellular Signaling Peptides and Proteins::Nerve Growth Factors::Neuregulins [Medical Subject Headings], Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Base Sequence::Repetitive Sequences, Nucleic Acid::Tandem Repeat Sequences::Inverted Repeat Sequences::Clustered Regularly Interspaced Short Palindromic Repeats [Medical Subject Headings], Epigenetics, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Cell- and Tissue-Based Therapy [Medical Subject Headings], Biology (General), Gene, neuronal differentiation, mesenchymal stem cells, General Immunology and Microbiology, Fibroblast growth factor receptor 1, Mesenchymal stem cell, epigenetic changes, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic [Medical Subject Headings], Nervous system Diseases, Adipose tissues, Mesenchymal Stem Cells, Epigenètica, Cell biology, Teixit adipós, Neuronal differentiation, Essential gene, Proteína 9 asociada a CRISPR, Diseases::Nervous System Diseases [Medical Subject Headings], Nervous system--Diseases, CRISPR/dCas9, General Agricultural and Biological Sciences, Epigénesis genética, Chemicals and Drugs::Biological Factors::Biological Markers::Biomarkers, Pharmacological [Medical Subject Headings]
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
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المؤلفون: Marina Cortijo-Gutiérrez, Karim Benabdellah, Noelia Maldonado-Pérez, Sabina Sánchez-Hernández, Rosario M. Sanchez Martin, Araceli Aguilar-González, Iris Ramos-Hernández, Francisco Martin, Beatriz Guijarro-Albaladejo
المساهمون: [Sánchez-Hernández,S, Aguilar-González,A, Guijarro-Albaladejo,B, Maldonado-Pérez,N, Ramos-Hernández,I, Cortijo-Gutiérrez,M, Benabdellah,K, Martin,F] Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer-University of Granada-Andalusian Regional Government, Granada, Spain. [Aguilar-González,A, Sánchez Martín,RM] Department of Medicinal & Organic Chemistry and Excellence Research Unit of 'Chemistry Applied to Biomedicine and the Environment', Faculty of Pharmacy, University of Granada, Granada, Spain., This study was funded by the Spanish ISCIII Health Research Fund and the European Regional Development Fund (FEDER) through research grants PI15/02015, PI18/00337 (F.M.) and PI18/00330 (K.B.) The CECEyU and CSyF of the Junta de Andalucía EDER/European Cohesion Fund (FSE) for Andalusia provided the following research grants: 2016000073391-TRA, 2016000073332-TRA, PI-57069, CARTPI-0001-201 and PAIDI-Bio326 (F.M.) and PI-0014-2016 (K.B). K.B. held a Nicolas Monardes regional Ministry of Health contract (0006/2018). S.S.H is funded thanks to Fundación Poco Frecuente donations. A.A.-G. and N.M.-P. are funded by Spanish Ministry of Science and Innovation (SMSI) through fellowships FPU17/04327 and FPU17/02268 respectively. I.R.H is funded by the ISCIII through a PFIS fellowship (FI19/00163). M.C.-G. is funded by (SMSI) through fellowship GJ (PEJ-2018-001760-A).
المصدر: Cells
Cells, Vol 9, Iss 1492, p 1492 (2020)
Volume 9
Issue 6
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)مصطلحات موضوعية: efficacy, specificity, Proteínas fluorescentes verdes, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], chemistry.chemical_compound, Modelos estructurales, Models, Genes, Reporter, eGFP, CRISPR, Homologous directed recombination (HDR), Homologous Recombination, lcsh:QH301-705.5, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Genetic Therapy [Medical Subject Headings], homologous directed recombination (HDR), on-target integration, Gene Editing, Organisms::Viruses::RNA Viruses::Retroviridae::Lentivirus [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Gene Targeting [Medical Subject Headings], General Medicine, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Engineering [Medical Subject Headings], Proteína 9 asociada a CRISPR, Eficacia, Gene Targeting, Specificity, Safety, Genetic Engineering, dsRED, Recombination, Wiskott-Aldrich Syndrome Protein, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Biological::Models, Genetic [Medical Subject Headings], safety, Efficacy, ADN recombinante, Genetic Vectors, DNA, Recombinant, Locus (genetics), Computational biology, Biology, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Reporter [Medical Subject Headings], Article, Especificidad, models, Phenomena and Processes::Genetic Phenomena::Genetic Processes::Recombination, Genetic::Homologous Recombination [Medical Subject Headings], Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA::DNA, Recombinant [Medical Subject Headings], DNA donor, Homologous chromosome, Humans, Seguridad, Gene, CRISPR/Cas9, On-target integration, Models, Genetic, Lentivirus, Chemicals and Drugs::Macromolecular Substances::Polymers::Biopolymers::Microfilament Proteins::Wiskott-Aldrich Syndrome Protein Family::Wiskott-Aldrich Syndrome Protein [Medical Subject Headings], Reparación del ADN por recombinación, Genetic Therapy, Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genetic Vectors [Medical Subject Headings], Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::K562 Cells [Medical Subject Headings], Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic::Gene Silencing::CRISPR-Cas Systems [Medical Subject Headings], chemistry, lcsh:Biology (General), CRISPR-Cas Systems, K562 Cells, DNA, K562 cells
وصف الملف: application/pdf
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المؤلفون: Álvarez Eraso, Karen Luisa Fernanda
المساهمون: Baena García, Andrés
المصدر: Repositorio UdeA
Universidad de Antioquia
instacron:Universidad de Antioquiaمصطلحات موضوعية: Cell death, id.nlm.nih.gov/mesh/D050356 [http], Metabolismo de los Lípidos, Mycobacterium tuberculosis, id.nlm.nih.gov/mesh/D016923 [http], CRISPR-associated protein 9, Muerte celular, ARN, Lipid metabolism, id.nlm.nih.gov/mesh/D015870 [http], RNA, Proteína 9 Asociada a CRISPR, Gene expression, id.nlm.nih.gov/mesh/D012313 [http], id.nlm.nih.gov/mesh/D000076987 [http], id.nlm.nih.gov/mesh/D009169 [http], Expresión génica
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3056::515b33769b8eee287c51c901c9b20ddd
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