المؤلفون: Hebert H; School of Engineering Sciences in Chemistry, Biotechnology and Health, Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, 14152 Huddinge, Sweden. Electronic address: hansh@kth.se., Sönmez E; Department of Chemistry - BMC, Box 576, SE-751 23 Uppsala, Sweden., Purhonen P; School of Engineering Sciences in Chemistry, Biotechnology and Health, Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, 14152 Huddinge, Sweden., Widersten M; Department of Chemistry - BMC, Box 576, SE-751 23 Uppsala, Sweden. Electronic address: mikael.widersten@kemi.uu.se.

المصدر: Structure (London, England : 1993) [Structure] 2024 Sep 05; Vol. 32 (9), pp. 1322-1326.e4. Date of Electronic Publication: 2024 Jul 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

مواضيع طبية MeSH: Aldehydes*/chemistry , Aldehydes*/metabolism , Ketones*/chemistry , Ketones*/metabolism , Catalytic Domain* , Fructose-Bisphosphate Aldolase*/chemistry , Fructose-Bisphosphate Aldolase*/metabolism , Fructose-Bisphosphate Aldolase*/genetics , Protein Engineering*, Models, Molecular ; Cryoelectron Microscopy ; Substrate Specificity ; Imines/chemistry ; Imines/metabolism ; Protein Binding ; Acetaldehyde/chemistry ; Acetaldehyde/metabolism ; Acetaldehyde/analogs & derivatives ; Tyrosine/chemistry ; Tyrosine/metabolism ; Aldehyde-Lyases ; Escherichia coli Proteins

المؤلفون: Cheng F; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, China.; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China., Sun KX; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, China.; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China., Gong XX; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, China.; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China., Peng W; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, China.; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China., Zhang HY; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, China.; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China., Liang XH; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, China.; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China., Xue YP; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, China.; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China., Zheng YG; Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, China.; The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China.

المصدر: Biotechnology and bioengineering [Biotechnol Bioeng] 2024 Sep; Vol. 121 (9), pp. 2893-2906. Date of Electronic Publication: 2024 Jun 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE

مواضيع طبية MeSH: D-Amino-Acid Oxidase*/metabolism , D-Amino-Acid Oxidase*/genetics , D-Amino-Acid Oxidase*/chemistry , Escherichia coli*/genetics , Escherichia coli*/metabolism , Escherichia coli*/enzymology , Caenorhabditis elegans*/genetics , Caenorhabditis elegans*/enzymology , Caenorhabditis elegans*/metabolism , Protein Engineering*/methods , Aminobutyrates*/metabolism , Aminobutyrates*/chemistry, Animals ; Deamination ; Caenorhabditis elegans Proteins/metabolism ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/chemistry

المؤلفون: Koopmeiners S; Biochemistry III, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Gilzer D; Structural Biochemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Widmann C; Structural Biochemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Berelsmann N; Biochemistry III, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Sproß J; Industrial Organic Chemistry and Biotechnology, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Niemann HH; Structural Biochemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Fischer von Mollard G; Biochemistry III, Department of Chemistry, Bielefeld University, Bielefeld, Germany.

المصدر: FEBS letters [FEBS Lett] 2024 Sep; Vol. 598 (18), pp. 2306-2320. Date of Electronic Publication: 2024 Aug 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE

مواضيع طبية MeSH: L-Amino Acid Oxidase*/chemistry , L-Amino Acid Oxidase*/metabolism , L-Amino Acid Oxidase*/genetics , Hebeloma*/enzymology , Hebeloma*/genetics , Hebeloma*/metabolism , Hebeloma*/chemistry , Protein Engineering* , Fungal Proteins*/chemistry , Fungal Proteins*/genetics , Fungal Proteins*/metabolism, Substrate Specificity ; Crystallography, X-Ray ; Models, Molecular ; Catalytic Domain ; Protein Conformation

المؤلفون: Milisavljevic M; Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States.; Center for Synthetic Biology, Northwestern University, Evanston, Illinois 60208, United States., Rodriguez TR; Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States., Carlson CK; Department of Biomedical Engineering, University of California, Irvine, California 92697, United States.; Center for Synthetic Biology, University of California, Irvine, California 92697, United States., Liu CC; Department of Biomedical Engineering, University of California, Irvine, California 92697, United States.; Center for Synthetic Biology, University of California, Irvine, California 92697, United States., Tyo KEJ; Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States.; Center for Synthetic Biology, Northwestern University, Evanston, Illinois 60208, United States.

المصدر: ACS synthetic biology [ACS Synth Biol] 2024 Aug 16; Vol. 13 (8), pp. 2492-2504. Date of Electronic Publication: 2024 Jul 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

مواضيع طبية MeSH: Protein Engineering*/methods , DNA-Directed DNA Polymerase*/metabolism , DNA-Directed DNA Polymerase*/genetics , DNA-Directed DNA Polymerase*/chemistry , DNA Nucleotidylexotransferase*/metabolism , DNA Nucleotidylexotransferase*/chemistry , DNA Nucleotidylexotransferase*/genetics, High-Throughput Screening Assays/methods ; DNA, Single-Stranded/genetics ; DNA, Single-Stranded/metabolism ; Deoxyribonucleotides/metabolism ; Mutation

المؤلفون: Gokulu IS; Department of Chemical Engineering, Columbia University, New York, New York 10027, United States., Banta S; Department of Chemical Engineering, Columbia University, New York, New York 10027, United States.

المصدر: ACS synthetic biology [ACS Synth Biol] 2024 Aug 16; Vol. 13 (8), pp. 2600-2610. Date of Electronic Publication: 2024 Aug 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

مواضيع طبية MeSH: Protein Engineering*/methods , Alcohol Dehydrogenase*/genetics , Alcohol Dehydrogenase*/metabolism , Alcohol Dehydrogenase*/chemistry , DNA*/metabolism , DNA*/chemistry , DNA*/genetics , Biocatalysis* , Catalytic Domain*, Substrate Specificity

المؤلفون: Mukherjee M; Astex Pharmaceuticals, Cambridge CB4 0QA, UK. Electronic address: manjeet.mukherjee@astx.com., Day PJ; Astex Pharmaceuticals, Cambridge CB4 0QA, UK., Laverty D; Astex Pharmaceuticals, Cambridge CB4 0QA, UK., Bueren-Calabuig JA; Astex Pharmaceuticals, Cambridge CB4 0QA, UK., Woodhead AJ; Astex Pharmaceuticals, Cambridge CB4 0QA, UK., Griffiths-Jones C; Astex Pharmaceuticals, Cambridge CB4 0QA, UK., Hiscock S; Astex Pharmaceuticals, Cambridge CB4 0QA, UK., East C; Astex Pharmaceuticals, Cambridge CB4 0QA, UK., Boyd S; Astex Pharmaceuticals, Cambridge CB4 0QA, UK., O'Reilly M; Astex Pharmaceuticals, Cambridge CB4 0QA, UK.

المصدر: Structure (London, England : 1993) [Structure] 2024 Aug 08; Vol. 32 (8), pp. 1040-1048.e3. Date of Electronic Publication: 2024 Jun 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

مواضيع طبية MeSH: Protein Engineering*/methods , Drug Design* , Cyclin-Dependent Kinases*/chemistry , Cyclin-Dependent Kinases*/metabolism , Cyclin-Dependent Kinases*/antagonists & inhibitors , Cyclin-Dependent Kinases*/genetics , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/pharmacology , Cyclin-Dependent Kinase-Activating Kinase* , Models, Molecular*, Humans ; Crystallography, X-Ray ; Protein Binding ; Binding Sites

المؤلفون: Moore EJ, Rice M, Roy G, Zhang W, Marelli M

المصدر: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2024 Aug; Vol. 54 (8), pp. 469-491. Date of Electronic Publication: 2024 Sep 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/drug therapy , Immunoconjugates* , Protein Engineering*/methods, Humans ; Drug Delivery Systems ; Antineoplastic Agents/pharmacology

المؤلفون: Wang D; Department of Chemistry, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo, 152-8551, Japan., Miyanaga A; Department of Chemistry, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo, 152-8551, Japan.; Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan., Chisuga T; Department of Chemistry, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo, 152-8551, Japan.; Present address, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, Shizuoka, 422-8526, Japan., Kudo F; Department of Chemistry, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo, 152-8551, Japan., Eguchi T; Department of Chemistry, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo, 152-8551, Japan.

المصدر: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Aug 01; Vol. 25 (15), pp. e202400383. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

مواضيع طبية MeSH: Phenylalanine*/metabolism , Phenylalanine*/chemistry , Protein Engineering*, Substrate Specificity ; Models, Molecular

المؤلفون: Imai M; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Colas K; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

المصدر: ChemPlusChem [Chempluschem] 2024 Aug; Vol. 89 (8), pp. e202400152. Date of Electronic Publication: 2024 May 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101580948 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2192-6506 (Electronic) Linking ISSN: 21926506 NLM ISO Abbreviation: Chempluschem Subsets: MEDLINE

مواضيع طبية MeSH: Peptides*/chemistry , Epitopes*/chemistry , Protein Engineering*/methods, Humans ; Proteins/chemistry

المؤلفون: Das D; Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai, India., Ainavarapu SRK; Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai, India.

المصدر: The FEBS journal [FEBS J] 2024 Aug; Vol. 291 (16), pp. 3581-3596. Date of Electronic Publication: 2024 Apr 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

مواضيع طبية MeSH: Protein Engineering*/methods, Protein Stability ; Proteins/chemistry ; Proteins/genetics ; Proteins/metabolism ; Thermodynamics ; Humans ; Models, Molecular ; Protein Conformation ; Protein Folding