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1رسالة جامعية
المؤلفون: Vita, Marina
مصطلحات موضوعية: Purines -- chemistry, Purines -- pharmacology, Purines -- pharmacokinetics, Antineoplastic agents -- chemistry, Antineoplastic agents -- pharmacology, Antineoplastic agents -- pharmacokinetics, Cyclin-dependent kinases -- antagonists & inhibitors, Protein kinase inhibitors -- chemistry, Protein kinase inhibitors -- pharmacology, Protein kinase inhibitors -- pharmacokinetics
URL الوصول: http://diss.kib.ki.se/2005/91-7140-302-7/
Degree: Diss. (sammanfattning) Stockholm : Karolinska institutet, 2005
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المؤلفون: Dong, Zhenyu, Noda, Kousuke, Kanda, Atsuhiro, Fukuhara, Junichi, Ando, Ryo, Murata, Miyuki, Saito, Wataru, Hagiwara, Masatoshi, Ishida, Susumu
المصدر: Molecular Vision
مصطلحات موضوعية: Male, Vascular Endothelial Growth Factor A, Macrophages/pathology, Protein Serine-Threonine Kinases, Protein-Serine-Threonine Kinases/antagonists & inhibitors, Vascular Endothelial Growth Factor A/metabolism, Protein-Serine-Threonine Kinases/metabolism, Mice, Choroidal Neovascularization/pathology, Animals, Macrophages/metabolism, Protein Kinase Inhibitors, Inflammation, Macrophages/drug effects, Cell Adhesion Molecules/metabolism, Macrophages, Choroidal Neovascularization/enzymology, Mice, Inbred C57BL, Choroidal Neovascularization/drug therapy, eye diseases, Choroidal Neovascularization, Protein Kinase Inhibitors/pharmacology, Protein Kinase Inhibitors/therapeutic use, Protein Kinase Inhibitors/chemistry, sense organs, Vascular Endothelial Growth Factor A/antagonists & inhibitors, Cell Adhesion Molecules, Inflammation/pathology, Research Article
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2b8d69329927b9b7b02859517efe757c
http://hdl.handle.net/2115/54611 -
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المؤلفون: Soo Chan Lee, Anne-Claude Gingras, Joseph Heitman, Paola Coccetti, Corey Nislow, Karolina Niewola-Staszkowska, Ron Ammar, Katja Döhl, A. A. Leslie Gunatilaka, Anna F. Averette, Taeyup Kim, David R. Andes, Yong Sun Bahn, Lutz Schmitt, E. M. Kithsiri Wijeratne, G. M. Kamal B. Gunaherath, Frederick P. Roth, Dominique Sanglard, Leah E. Cowen, Robbie Loewith, Farida Tripodi, Tanvi Shekhar-Guturja, Jean-Philippe Lambert
المساهمون: Shekhar Guturja, T, Gunaherath, G, Wijeratne, E, Lambert, J, Averette, A, Lee, S, Kim, T, Bahn, Y, Tripodi, F, Ammar, R, Döhl, K, Niewola Staszkowska, K, Schmitt, L, Loewith, R, Proth, F, Sanglard, D, Andes, D, Nislow, C, Coccetti, P, Gingras, A, Heitman, J, Gunatilaka, A, Ecowen, L
المصدر: Nature chemical biology
Nature chemical biology, vol. 12, no. 10, pp. 867-875
Nature chemical biology, Vol. 12, No 10 (2016) pp. 867-875مصطلحات موضوعية: 0301 basic medicine, Antifungal Agents, Mutant, Drug Resistance, Drug resistance, Antifungal Agents/chemistry/pharmacology, chemistry.chemical_compound, ddc:590, Signal Transduction/drug effects, Depsipeptides, Mycoses/drug therapy/microbiology, biology, Kinase, ATP-Binding Cassette Transporters/genetics, ATP-Binding Cassette Transporters/metabolism, Antifungal Agents/chemistry, Antifungal Agents/pharmacology, Depsipeptides/chemical synthesis, Depsipeptides/chemistry, Depsipeptides/pharmacology, Drug Resistance, Fungal/drug effects, Drug Resistance, Multiple/drug effects, Fungi/drug effects, Fungi/metabolism, HSP90 Heat-Shock Proteins/antagonists & inhibitors, HSP90 Heat-Shock Proteins/metabolism, Microbial Sensitivity Tests, Mycoses/drug therapy, Mycoses/microbiology, Protein Kinase Inhibitors/chemical synthesis, Protein Kinase Inhibitors/chemistry, Protein Kinase Inhibitors/pharmacology, Saccharomyces cerevisiae Proteins/genetics, Saccharomyces cerevisiae Proteins/metabolism, Small Molecule Libraries/chemistry, Small Molecule Libraries/pharmacology, TOR Serine-Threonine Kinases/antagonists & inhibitors, TOR Serine-Threonine Kinases/metabolism, TOR Serine-Threonine Kinases, Fungal/drug effects, BIO/11 - BIOLOGIA MOLECOLARE, Hsp90, BIO/10 - BIOCHIMICA, Drug Resistance, Multiple, 3. Good health, Biotinylation, Protein Kinase Inhibitors/chemical synthesis/chemistry/pharmacology, Efflux, Signal Transduction, Saccharomyces cerevisiae Proteins, 030106 microbiology, Saccharomyces cerevisiae Proteins/genetics/metabolism, Article, Microbiology, Fungi/drug effects/metabolism, Small Molecule Libraries, 03 medical and health sciences, Drug Resistance, Fungal, ddc:570, Small Molecule Libraries/chemistry/pharmacology, HSP90 Heat-Shock Proteins, Molecular Biology, Protein Kinase Inhibitors, Cell Biology, antifungal small molecule, CK2 pathway,TOR signaling, Fungi, Cell Biology, BIO/19 - MICROBIOLOGIA GENERALE, Depsipeptides/chemical synthesis/chemistry/pharmacology, TOR Serine-Threonine Kinases/antagonists & inhibitors/metabolism, Beauvericin, TOR signaling, 030104 developmental biology, chemistry, Mycoses, biology.protein, ATP-Binding Cassette Transporters/genetics/metabolism, HSP90 Heat-Shock Proteins/antagonists & inhibitors/metabolism, ATP-Binding Cassette Transporters, Multiple/drug effects
وصف الملف: application/pdf
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المؤلفون: Laurent Pottier, Delphine Lamoral-Theys, François Dufrasne, Alexander Kornienko, Jean Neve, Laurent Ingrassia, Robert Kiss, Jacques Dubois
المصدر: Current medicinal chemistry, 17 (9
مصطلحات موضوعية: medicine.medical_treatment, Flavonoids -- chemistry, Antineoplastic Agents, Pharmacology, Biochemistry, Protein Kinases -- chemistry, Targeted therapy, Antineoplastic Agents -- chemistry, Structure-Activity Relationship, chemistry.chemical_compound, Phenols, Antineoplastic Agents -- pharmacology, Stilbenes, Drug Discovery, medicine, Stilbenes -- chemistry, Kinase activity, Protein Kinase Inhibitors, Flavonoids, Phenols -- pharmacology, Kinase, Protein Kinase Inhibitors -- chemistry, Organic Chemistry, Polyphenols, food and beverages, Cancer, Sciences bio-médicales et agricoles, Flavonoids -- pharmacology, Green tea, medicine.disease, chemistry, Polyphenol, Protein Kinase Inhibitors -- pharmacology, Curcumin, Molecular Medicine, Protein Kinases -- metabolism, Stilbenes -- pharmacology, Signal transduction, Phenols -- chemistry, Protein Kinases
وصف الملف: 1 full-text file(s): application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77514fbd666de393cdab7220e529785c
https://doi.org/10.2174/092986710790712183 -
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المؤلفون: Doerig, Christian, Billker, Oliver, Pratt, David, Endicott, Jane
المصدر: Biochimica et Biophysica Acta. 1754(1-2):132-150
مصطلحات موضوعية: Animals, Antimalarials/*metabolism/pharmacology, Antiprotozoal Agents/chemistry/pharmacology, Cyclins/chemistry, Drug Design, Humans, Life Cycle Stages, Malaria, Falciparum/drug therapy/metabolism, Models, Biological, Genetic, Molecular Structure, Plasmodium falciparum/drug effects/metabolism, Protein Kinase Inhibitors/*chemistry/pharmacology, Protein Kinases/drug effects/*metabolism, Protozoan Proteins/chemistry, Structure-Activity Relationship
وصف الملف: print
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المؤلفون: Colinge, Jacques, Cesar-Razquin, A., Huber, K., Breitwieser, F. P., Majek, P., Superti-Furga, G.
المساهمون: Institut de recherche en cancérologie de Montpellier (IRCM - U896 Inserm - UM1), Université Montpellier 1 (UM1)-CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)
المصدر: Journal of Proteomics
Journal of Proteomics, Elsevier, 2014, 107, pp.113--27. ⟨10.1016/j.jprot.2014.03.028⟩مصطلحات موضوعية: System biology, Bioinformatics, Databases, Protein, Biophysics, Drugs, Molecular, Kinases, Network, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biochemistry, Article, Protein Kinases/chemistry/genetics/metabolism, Evolution, Molecular, Evolution, Humans, Protein Kinase Inhibitors/chemistry, Databases, Protein, Protein Kinase Inhibitors, Protein Kinases
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المؤلفون: Kumiko, Nagashima, Stuart D, Shumway, Sriram, Sathyanarayanan, Albert H, Chen, Brian, Dolinski, Youyuan, Xu, Heike, Keilhack, Thi, Nguyen, Maciej, Wiznerowicz, Lixia, Li, Bart A, Lutterbach, An, Chi, Cloud, Paweletz, Timothy, Allison, Youwei, Yan, Sanjeev K, Munshi, Anke, Klippel, Manfred, Kraus, Ekaterina V, Bobkova, Sujal, Deshmukh, Zangwei, Xu, Uwe, Mueller, Alexander A, Szewczak, Bo-Sheng, Pan, Victoria, Richon, Roy, Pollock, Peter, Blume-Jensen, Alan, Northrup, Jannik N, Andersen
مصطلحات موضوعية: animal structures, Protein Serine-Threonine Kinases, Crystallography, X-Ray, Neoplasm Proteins - Antagonists & Inhibitors - Genetics - Metabolism, Dogs, Allosteric Regulation, Catalytic Domain, Neoplasms, Cell Line, Tumor, Animals, Humans, Phosphorylation, Protein Kinase Inhibitors, Cell Proliferation, Drug Screening Assays, Antitumor - Methods, Phosphorylation - Drug Effects - Genetics, Catalytic Domain - Genetics, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Protein-Serine-Threonine Kinases - Antagonists & Inhibitors - Genetics - Metabolism, Neoplasm Proteins, Allosteric Regulation - Drug Effects - Genetics, Neoplasms - Drug Therapy - Enzymology - Genetics, Cell Proliferation - Drug Effects, Protein Kinase Inhibitors - Chemistry - Pharmacology, Drug Screening Assays, Antitumor, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffa77558274950b04bf7d0ff36cc73f0
http://hdl.handle.net/10722/156005 -
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المؤلفون: Eidarus Salah, Joanna I. Loizou, Branka Radic, Ulrika Warpman Berglund, Alexey Stukalov, Giulio Superti-Furga, Jonathan M. Elkins, Camilla Göktürk, Ann-Sofie Jemth, Kia Strömberg, Stefan Knapp, Kumar Sanjiv, Therese Pham, Manuela Gridling, Keiryn L. Bennett, Kilian Huber, Thomas Helleday, Jacques Colinge
المساهمون: Institut de recherche en cancérologie de Montpellier (IRCM - U896 Inserm - UM1), Université Montpellier 1 (UM1)-CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)
المصدر: Scopus-Elsevier
Nature
Nature, Nature Publishing Group, 2014, 508, pp.222--7. ⟨10.1038/nature13194⟩
Nature; Vol 508مصطلحات موضوعية: Models, Molecular, Proteomics, Phosphoric Monoester Hydrolases/*antagonists &, DNA Repair, Pyridines, Protein Conformation, ras Proteins/genetics, GTPase, Mice, SCID, medicine.disease_cause, Nucleotides/metabolism, Pyridines/chemistry/*pharmacology, Substrate Specificity, chemistry.chemical_compound, Mice, Antineoplastic Agents/chemistry/*pharmacology, Models, Homeostasis, chemistry.chemical_classification, Multidisciplinary, Kinase, Nucleotides, Protein Kinase Inhibitors/chemistry/*pharmacology, 3. Good health, Biochemistry, Colonic Neoplasms, Aminoquinolines, Female, KRAS, Crystallization, Pyrazoles/chemistry/*pharmacology, medicine.drug, Homeostasis/drug effects, DNA repair, Single-Stranded/drug effects, Antineoplastic Agents, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, SCID, Proto-Oncogene Proteins p21(ras), inhibitors/biosynthesis/chemistry/*metabolism, Crizotinib, Proto-Oncogene Proteins, medicine, Humans, Animals, DNA Breaks, Single-Stranded, Protein Kinase Inhibitors, Animal, DNA Breaks, Molecular, DNA Repair Enzymes/*antagonists & inhibitors/biosynthesis/chemistry/*metabolism, Xenograft Model Antitumor Assays, Phosphoric Monoester Hydrolases, Aminoquinolines/pharmacology, Disease Models, Animal, Proto-Oncogene Proteins/genetics, Enzyme, DNA Repair Enzymes, Colonic Neoplasms/drug therapy/genetics/pathology, chemistry, Disease Models, Cancer research, ras Proteins, Pyrazoles, DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf6d6ad2f3b07657ef3e0a6f7a30e0c
http://www.scopus.com/inward/record.url?eid=2-s2.0-84899619048&partnerID=MN8TOARS -
9مورد إلكتروني
مصطلحات الفهرس: Animals, Cell Adhesion Molecules/metabolism, Choroidal Neovascularization/drug therapy, Choroidal Neovascularization/enzymology, Choroidal Neovascularization/pathology, Inflammation/pathology, Macrophages/drug effects, Macrophages/metabolism, Macrophages/pathology, Male, Mice, Mice, Inbred C57BL, Protein Kinase Inhibitors/chemistry, Protein Kinase Inhibitors/pharmacology, Protein Kinase Inhibitors/therapeutic use, Protein-Serine-Threonine Kinases/antagonists & inhibitors, Protein-Serine-Threonine Kinases/metabolism, Vascular Endothelial Growth Factor A/antagonists & inhibitors, Vascular Endothelial Growth Factor A/metabolism, 496, article
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10مورد إلكتروني
مصطلحات الفهرس: Animals, Cell Adhesion Molecules/metabolism, Choroidal Neovascularization/drug therapy, Choroidal Neovascularization/enzymology, Choroidal Neovascularization/pathology, Inflammation/pathology, Macrophages/drug effects, Macrophages/metabolism, Macrophages/pathology, Male, Mice, Mice, Inbred C57BL, Protein Kinase Inhibitors/chemistry, Protein Kinase Inhibitors/pharmacology, Protein Kinase Inhibitors/therapeutic use, Protein-Serine-Threonine Kinases/antagonists & inhibitors, Protein-Serine-Threonine Kinases/metabolism, Vascular Endothelial Growth Factor A/antagonists & inhibitors, Vascular Endothelial Growth Factor A/metabolism, 496, Journal Article, VoR
URL:
http://hdl.handle.net/2115/54611 https://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/54611/1/Mol%20Vis_19_536-543.pdf
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