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1
المؤلفون: Nasimian, Ahmad, Al Ashiri, Lina, Ahmed, Mehreen, Duan, Hongzhi, Zhang, Xiaoyue, Rönnstrand, Lars, Kazi, Julhash U
المصدر: International Journal of Molecular Sciences StemTherapy: National Initiative on Stem Cells for Regenerative Therapy EpiHealth: Epidemiology for Health. 24(4)
مصطلحات موضوعية: Humans, Sorafenib/therapeutic use, Tyrosine Protein Kinase Inhibitors, Mutation, Protein Kinase Inhibitors/pharmacology, Leukemia, Myeloid, Acute/genetics, fms-Like Tyrosine Kinase 3/genetics, Drug Resistance, Neoplasm/genetics, Cell Line, Tumor, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Farmakologi och toxikologi, Medical and Health Sciences, Basic Medicine, Pharmacology and Toxicology, Klinisk medicin, Hematologi, Clinical Medicine, Hematology
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2دورية أكاديمية
المؤلفون: Ren, Ping, Zhang, Huiping, Qiu, Fang, Liu, Yu-Qiang, Gu, Huaiyu, O'Dowd, Diane K, Zhou, Qun-Yong, Hu, Wang-Ping
المصدر: PloS one. 6(6)
مصطلحات موضوعية: Animals, Electric Conductivity, Electrophysiological Processes: drug effects, Gastrointestinal Hormones: metabolism, Inhibitory Postsynaptic Potentials: drug effects, Male, Neurons: cytology, drug effects, metabolism, Neuropeptides: metabolism, Protein Kinase C: antagonists & inhibitors, metabolism, Protein Kinase Inhibitors: pharmacology, Rats, Rats, Sprague-Dawley, Receptors, GABA-A: metabolism, Suprachiasmatic Nucleus: cytology, drug effects, metabolism, physiology, gamma-Aminobutyric Acid: pharmacology
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/0j53r5gx
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3دورية أكاديمية
المؤلفون: Chan, Wayne W, Wise, Scott C, Kaufman, Michael D, Ahn, Yu Mi, Ensinger, Carol L, Haack, Torsten, Hood, Molly M, Jones, Jennifer, Lord, John W, Lu, Wei Ping, Miller, David, Patt, William C, Smith, Bryan D, Petillo, Peter A, Rutkoski, Thomas J, Telikepalli, Hanumaiah, Vogeti, Lakshminarayana, Yao, Tony, Chun, Lawrence, Clark, Robin, Evangelista, Peter, Gavrilescu, L Cristina, Lazarides, Katherine, Zaleskas, Virginia M, Stewart, Lance J, Van Etten, Richard A, Flynn, Daniel L
المصدر: Cancer cell. 19(4)
مصطلحات موضوعية: Animals, Cell Line, Tumor, Cell Proliferation: drug effects, Cell Survival: drug effects, Drug Design, Fusion Proteins, bcr-abl: antagonists & inhibitors, chemistry, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: drug therapy, Male, Mice, Mice, Inbred BALB C, Mutation, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma: drug therapy, Protein Conformation, Protein Kinase Inhibitors: pharmacology, Protein-Tyrosine Kinases: antagonists & inhibitors, chemistry
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/6qk7857n
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4دورية أكاديمية
المؤلفون: Bellodi, Cristian, Lidonnici, Maria Rosa, Hamilton, Ashley, Helgason, G Vignir, Soliera, Angela Rachele, Ronchetti, Mattia, Galavotti, Sara, Young, Kenneth W, Selmi, Tommaso, Yacobi, Rinat, Van Etten, Richard A, Donato, Nick, Hunter, Ann, Dinsdale, David, Tirrò, Elena, Vigneri, Paolo, Nicotera, Pierluigi, Dyer, Martin J, Holyoake, Tessa, Salomoni, Paolo, Calabretta, Bruno
المصدر: The Journal of clinical investigation. 119(5)
مصطلحات موضوعية: Animals, Antineoplastic Agents: pharmacology, therapeutic use, Autophagy: drug effects, physiology, Benzamides, Calcium: metabolism, Cell Death: drug effects, physiology, Cell Line, Tumor, Chloroquine: pharmacology, therapeutic use, Endoplasmic Reticulum: drug effects, metabolism, Fusion Proteins, bcr-abl: antagonists & inhibitors, genetics, Gene Expression: drug effects, genetics, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: drug therapy, metabolism, pathology, Macrolides: pharmacology, therapeutic use, Mice, Mice, Inbred C3H, Microtubule-Associated Proteins: metabolism, Neoplastic Stem Cells: cytology, drug effects, metabolism, Piperazines: pharmacology, therapeutic use, Protein Kinase Inhibitors: pharmacology, therapeutic use, Protein-Tyrosine Kinases: antagonists & inhibitors, Pyrimidines: pharmacology, therapeutic use, RNA Interference, Thiazoles: pharmacology, therapeutic use, Transcription Factor CHOP: genetics, Xenograft Model Antitumor Assays
وصف الملف: application/pdf
URL الوصول: https://escholarship.org/uc/item/1pw7d036
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5
المؤلفون: Fanny Seraphine Krebs, Bianca Moura, Edoardo Missiaglia, Veronica Aedo-Lopez, Olivier Michielin, Petros Tsantoulis, Bettina Bisig, Mounir Trimech, Vincent Zoete, Krisztian Homicsko
المصدر: International journal of molecular sciences, vol. 24, no. 5, pp. 4520
مصطلحات موضوعية: Inorganic Chemistry, Male, Humans, Skin Neoplasms/genetics, Melanoma/genetics, Pyridones/therapeutic use, Pyrimidinones/therapeutic use, Protein Kinase Inhibitors/pharmacology, Mitogen-Activated Protein Kinase Kinases/genetics, Proto-Oncogene Proteins B-raf/genetics, Mutation, MAP Kinase Kinase 1/genetics, MAP2K1, cancer, modelling, mutation, triple-negative melanoma, Organic Chemistry, General Medicine, Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy, Catalysis, Computer Science Applications
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c2d7b7bfc9703cd98b057de8fcea53
https://serval.unil.ch/notice/serval:BIB_E3A48A3138B7 -
6
المؤلفون: Giulia Franciosa, Jesper V. Olsen
المصدر: Franciosa, G & Olsen, J V 2023, ' Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors ', OncoTarget, vol. 14, pp. 281-283 . https://doi.org/10.18632/oncotarget.28392
مصطلحات موضوعية: Enzyme Inhibitors/pharmacology, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics, Oncology, Cell Line, Tumor, Protein Kinase Inhibitors/pharmacology, Humans, Tyrosine, Phosphorylation
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b600517b73be7f6aea170398ffae5573
https://curis.ku.dk/portal/da/publications/impact-of-shp2-tyrosine-phosphorylation-on-the-development-of-acquired-resistance-to-allosteric-shp2-inhibitors (ca2d5b9b-3d94-46d2-9081-c5b372fdd0c6).html -
7دورية أكاديمية
المؤلفون: Mitroshina, Еlena V, Mishchenko, Tatiana A, Shirokova, Olesya M, Astrakhanova, Tatiana A, Loginova, Maria M, Epifanova, Ekaterina, Babaev, Alexey A, Tarabykin, Victor S, Vedunova, Maria V
المصدر: Oxidative Medicine and Cellular Longevity, 2019, 1036907 (2019)
مصطلحات موضوعية: Glial Cell Line-Derived Neurotrophic Factor, Hypoxia-Inducible Factor 1, alpha Subunit, Neuroprotective Agents, Protein Kinase Inhibitors, EC 2.7.10.1 (Proto-Oncogene Proteins c-ret), EC 2.7.11.1 (Proto-Oncogene Proteins c-akt), SY7Q814VUP (Calcium), Animals, Calcium/metabolism, Cell Hypoxia, Cell Survival/drug effects, Cells, Cultured, Glial Cell Line-Derived Neurotrophic Factor/pharmacology, Hippocampus/cytology/drug effects/metabolism/ultrastructure, Hypoxia-Inducible Factor 1, alpha Subunit/genetics/metabolism, Mice, Mitochondria/drug effects/metabolism, Neuroprotective Agents/pharmacology, Phosphatidylinositol 3-Kinases/metabolism, Protein Kinase Inhibitors/pharmacology, Proto-Oncogene Proteins c-akt/metabolism, Proto-Oncogene Proteins c-ret/antagonists & inhibitors/metabolism, Signal Transduction/drug effects, Life sciences, Anatomy (cytology, histology, embryology...) & physiology, Sciences du vivant, Anatomie (cytologie, histologie, embryologie...) & physiologie
Relation: urn:issn:1942-0900; urn:issn:1942-0994
URL الوصول: https://orbi.uliege.be/handle/2268/303076
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8
المؤلفون: Carolien Eggermont, Philippe Giron, Maxim Noeparast, Hugo Vandenplas, Pedro Aza-Blanc, Gustavo J. Gutierrez, Jacques De Grève
المساهمون: Laboratory for Medical and Molecular Oncology, Clinical sciences, Faculty of Medicine and Pharmacy, Medical Genetics, Basic (bio-) Medical Sciences, Biology
مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Mutation/genetics, Carcinoma, Non-Small-Cell Lung/drug therapy, Immunology, Drug Resistance, Neoplasm/genetics, Receptor Protein-Tyrosine Kinases/metabolism, Afatinib, Cellular and Molecular Neuroscience, Carcinoma, Non-Small-Cell Lung, Afatinib/pharmacology, ErbB Receptors/antagonists & inhibitors, Humans, Genetics(clinical), RNA, Small Interfering, Lung Neoplasms/drug therapy, Protein Kinase Inhibitors, Drug Tolerance/genetics, RNA, Small Interfering/genetics, Receptor Protein-Tyrosine Kinases, Drug Tolerance, Cell Biology, ErbB Receptors, Drug Resistance, Neoplasm, Protein Kinase Inhibitors/pharmacology, Mutation, oncology, Fibroblast Growth Factor 1, Fibroblast Growth Factor 1/metabolism
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8d369e1425569db56d294a0d66c876
https://hdl.handle.net/20.500.14017/e1c070ad-96c6-42f6-a7ad-d2c11f334822 -
9
المؤلفون: Högnäsbacka, Antonia, Poot, Alex J., Kooijman, Esther, Schuit, Robert C., Schreurs, Maxime, Verlaan, Mariska, van den Hoek, Johan, Heideman, Daniëlle A. M., Beaino, Wissam, van Dongen, Guus A. M. S., Vugts, Danielle J., Windhorst, Albert D.
المساهمون: Radiology and nuclear medicine, Pathology, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, Amsterdam Neuroscience - Brain Imaging, CCA - Cancer Treatment and quality of life, AII - Cancer immunology, AII - Inflammatory diseases
المصدر: Nuclear Medicine and Biology, 120-121. ELSEVIER SCIENCE INC
Nuclear Medicine and Biology, 120-121:108349. Elsevier Inc.
Högnäsbacka, A, Poot, A J, Kooijman, E, Schuit, R C, Schreurs, M, Verlaan, M, van den Hoek, J, Heideman, D A M, Beaino, W, van Dongen, G A M S, Vugts, D J & Windhorst, A D 2023, ' Synthesis and preclinical evaluation of two osimertinib isotopologues labeled with carbon-11 as PET tracers targeting the tyrosine kinase domain of the epidermal growth factor receptor ', Nuclear Medicine and Biology, vol. 120-121, 108349 . https://doi.org/10.1016/j.nucmedbio.2023.108349مصطلحات موضوعية: Cancer Research, Carcinoma, Non-Small-Cell Lung/drug therapy, ErbB Receptors/genetics, Carcinoma, Drug Resistance, Non-Small-Cell Lung/drug therapy, Aniline Compounds/pharmacology, Lung Neoplasms/diagnostic imaging, Mice, Drug Resistance, Neoplasm, Protein Kinase Inhibitors/pharmacology, Mutation, Neoplasm, Humans, Animals, Molecular Medicine, Female, Tissue Distribution, Radiology, Nuclear Medicine and imaging
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10رسالة جامعية
المؤلفون: Piltti, Juha
المساهمون: Umeå universitet. Institutionen för integrativ medicinsk biologi
مصطلحات موضوعية: Rho-kinase inhibition, Y-27632, Hypoxia, Cyclic stretching, Human chondrosarcoma 2/8 cells, Chondrocyte phenotype, Fibroblasts, Proteomics, Protein pathway analytics, Amides -- pharmacology, Fibroblasts -- cytology, Protein kinase inhibitors -- pharmacology, Pyridines -- pharmacology, rho-associated kinases -- antagonists & inhibitors, Chondrocytes -- metabolism, Chondrosarcoma -- metabolism, Chondrosarcoma -- pathology, Mitogen-activated protein kinases -- metabolism, Peptide elongation factor 2 -- metabolism, Phosphoproteins -- metabolism, Proteomics
Degree: Diss. (sammanfattning) Umeå : Umeå universitet, 2017