المؤلفون: Su D; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China., Zhu S; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China., Hou Z; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China. zfhou@yzu.edu.cn.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China. zfhou@yzu.edu.cn.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China. zfhou@yzu.edu.cn., Hao F; Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, 225300, People's Republic of China., Xu K; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China., Xu F; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China., Zhu Y; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China., Liu D; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China., Xu J; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China., Tao J; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou, 225009, Jiangsu, People's Republic of China. yzjptao@126.com.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou, 225009, People's Republic of China. yzjptao@126.com.; International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou, 225009, People's Republic of China. yzjptao@126.com.

المصدر: Parasites & vectors [Parasit Vectors] 2023 Oct 19; Vol. 16 (1), pp. 371. Date of Electronic Publication: 2023 Oct 19.

نوع المنشور: Evaluation Study; Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305 (Electronic) Linking ISSN: 17563305 NLM ISO Abbreviation: Parasit Vectors Subsets: MEDLINE

مواضيع طبية MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Swine Diseases*/genetics , Swine Diseases*/metabolism , Swine Diseases*/parasitology , Toxoplasma* , Toxoplasmosis*/genetics , Toxoplasmosis*/metabolism , Proto-Oncogene Proteins A-raf*/genetics , Proto-Oncogene Proteins A-raf*/metabolism, Animals ; Mice ; Apoptosis/genetics ; Apoptosis/immunology ; Caspase 3 ; Cells, Cultured ; Luciferases ; Swine/genetics ; Swine/metabolism ; Swine/parasitology

المؤلفون: Su W; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Mukherjee R; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Yaeger R; Department of Medicine, Memorial Hospital, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Son J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., Xu J; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Na N; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Merna Timaul N; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Hechtman J; Department of Pathology, Memorial Hospital, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Paroder V; Department of Radiology, Memorial Hospital, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Lin M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., Mattar M; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Qiu J; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Chang Q; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Zhao H; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Zhang J; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Little M; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Adachi Y; Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan., Han SW; UCSF Helen Diller Family Comprehensive Cancer Center, School of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Internal Medicine, Seoul National University Hospital, Seoul, 03080, South Korea., Taylor BS; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10065, USA; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Discovery and Applied Genomics, Loxo Oncology at Lilly, Stamford, CT 06901, USA., Ebi H; Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan; Division of Advanced Cancer Therapeutics, Nagoya University Graduate School of Medicine, Nagoya, 466-8650, Japan., Abdel-Wahab O; Department of Medicine, Memorial Hospital, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10065, USA., de Stanchina E; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Rudin CM; Department of Medicine, Memorial Hospital, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Jänne PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02215, USA., McCormick F; UCSF Helen Diller Family Comprehensive Cancer Center, School of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Frederick, MD 21701, USA., Yao Z; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Hospital, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Mechanistic Biology, Loxo Oncology at Lilly, New York, NY 10016, USA. Electronic address: zyao@loxooncology.com., Rosen N; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Hospital, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: rosenn@mskcc.org.

المصدر: Molecular cell [Mol Cell] 2022 Jul 07; Vol. 82 (13), pp. 2443-2457.e7. Date of Electronic Publication: 2022 May 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Neurofibromin 1*/metabolism , Proto-Oncogene Proteins A-raf*/metabolism , ras GTPase-Activating Proteins*/metabolism, ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Guanosine Triphosphate/metabolism ; Humans ; Protein Binding ; Signal Transduction

المؤلفون: Yen I; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA., Shanahan F; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA., Lee J; Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.; Department of Intelligence Precision Healthcare Convergence, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, South Korea., Hong YS; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Shin SJ; Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea., Moore AR; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA., Sudhamsu J; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA.; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA., Chang MT; Department of Bioinformatics, Genentech Inc., South San Francisco, CA, USA., Bae I; Department of New Chemical Entity Discovery, Hanmi Research Center, Hanmi Pharmaceutical Co., Ltd., Seoul, South Korea., Dela Cruz D; Department of Translational Oncology, Genentech Inc., South San Francisco, CA, USA., Hunsaker T; Department of Translational Oncology, Genentech Inc., South San Francisco, CA, USA., Klijn C; Department of Bioinformatics, Genentech Inc., South San Francisco, CA, USA., Liau NPD; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA., Lin E; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA., Martin SE; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA., Modrusan Z; Department of Microchemistry, Proteomics and Lipidomics, Genentech Inc., South San Francisco, CA, USA., Piskol R; Department of Bioinformatics, Genentech Inc., South San Francisco, CA, USA., Segal E; Department of Translational Oncology, Genentech Inc., South San Francisco, CA, USA., Venkatanarayan A; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA., Ye X; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA., Yin J; Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA., Zhang L; Department of Oncology Biomarker Development, Genentech Inc., South San Francisco, CA, USA., Kim JS; Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, South Korea., Lim HS; Department of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Kim KP; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Kim YJ; Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea., Han HS; Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, South Korea., Lee SJ; Department of Oncology/Hematology, Kyungpook National University Chilgok Hospital, Kyungpook National University, Daegu, South Korea., Kim ST; Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Jung M; Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea., Hong YH; Department of Clinical Research and Development, Hanmi Pharmaceutical Co., Ltd., Seoul, South Korea., Noh YS; Department of Clinical Research and Development, Hanmi Pharmaceutical Co., Ltd., Seoul, South Korea., Choi M; Department of Clinical Research and Development, Hanmi Pharmaceutical Co., Ltd., Seoul, South Korea., Han O; Department of Clinical Research and Development, Hanmi Pharmaceutical Co., Ltd., Seoul, South Korea., Nowicka M; Department of Oncology Biomarker Development, Genentech Inc., South San Francisco, CA, USA., Srinivasan S; Department of Oncology Biomarker Development, Genentech Inc., South San Francisco, CA, USA., Yan Y; Department of Oncology Biomarker Development, Genentech Inc., South San Francisco, CA, USA., Kim TW; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. twkimmd@amc.seoul.kr., Malek S; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA, USA. shivam@gene.com.

المصدر: Nature [Nature] 2021 Jun; Vol. 594 (7863), pp. 418-423. Date of Electronic Publication: 2021 May 05.

نوع المنشور: Clinical Trial, Phase I; Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Drug Resistance, Neoplasm/*genetics , Melanoma/*drug therapy , Melanoma/*genetics , Proto-Oncogene Proteins A-raf/*antagonists & inhibitors , Proto-Oncogene Proteins A-raf/*genetics , raf Kinases/*antagonists & inhibitors, Animals ; Cell Line ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Female ; Humans ; Melanoma/pathology ; Mice ; Protein Multimerization/drug effects ; Proto-Oncogene Proteins A-raf/chemistry ; raf Kinases/chemistry

المؤلفون: Meng LD; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Shi GD; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Ge WL; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Huang XM; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Chen Q; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Yuan H; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Wu PF; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Lu YC; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Shen P; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Zhang YH; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Cao SJ; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Miao Y; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China., Tu M; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China. Electronic address: tumin1215@163.com., Jiang KR; Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Pancreas Institute, Nanjing Medical University, Nanjing, PR China. Electronic address: jiangkuirongnjmu@sina.com.

المصدر: Cancer letters [Cancer Lett] 2020 Dec 01; Vol. 494, pp. 107-120. Date of Electronic Publication: 2020 Aug 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Heterogeneous-Nuclear Ribonucleoprotein Group A-B/*metabolism , Pancreatic Neoplasms/*pathology , Proto-Oncogene Proteins A-raf/*metabolism , RNA, Long Noncoding/*genetics , Ubiquitin/*metabolism, Animals ; Cell Line, Tumor ; Female ; Gene Expression Regulation, Neoplastic ; Heterogeneous-Nuclear Ribonucleoprotein Group A-B/genetics ; Humans ; MAP Kinase Signaling System ; Male ; Mice ; Neoplasm Metastasis ; Neoplasm Staging ; Neoplasm Transplantation ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/metabolism ; Prognosis ; Proteolysis ; Proto-Oncogene Proteins A-raf/genetics ; Sequence Analysis, RNA ; Up-Regulation

المؤلفون: Ranjpour M; Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India., Wajid S; Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India., Jain SK; Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India.; Department of Medical Biochemistry, HIMSR, Jamia Hamdard, New Delhi 110062, India.

المصدر: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2019; Vol. 19 (2), pp. 236-247.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101265649 Publication Model: Print Cited Medium: Internet ISSN: 1875-5992 (Electronic) Linking ISSN: 18715206 NLM ISO Abbreviation: Anticancer Agents Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular/*genetics , Liver Neoplasms/*genetics , Mixed Function Oxygenases/*genetics , Proto-Oncogene Proteins A-raf/*genetics, Animals ; Carcinoma, Hepatocellular/chemically induced ; Carcinoma, Hepatocellular/metabolism ; Diethylnitrosamine ; Humans ; Lipid Metabolism/genetics ; Liver Neoplasms/chemically induced ; Liver Neoplasms/metabolism ; Male ; Mixed Function Oxygenases/blood ; Mixed Function Oxygenases/metabolism ; Proteomics ; Proto-Oncogene Proteins A-raf/blood ; Proto-Oncogene Proteins A-raf/metabolism ; RNA, Messenger/blood ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Tandem Mass Spectrometry

المؤلفون: Rezaei Adariani S; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany., Buchholzer M; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany., Akbarzadeh M; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany., Nakhaei-Rad S; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany., Dvorsky R; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany., Ahmadian MR; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany reza.ahmadian@hhu.de.

المصدر: Biochemical Society transactions [Biochem Soc Trans] 2018 Dec 17; Vol. 46 (6), pp. 1393-1406. Date of Electronic Publication: 2018 Oct 31.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1470-8752 (Electronic) Linking ISSN: 03005127 NLM ISO Abbreviation: Biochem Soc Trans Subsets: MEDLINE

مواضيع طبية MeSH: Mitogen-Activated Protein Kinases/*metabolism , Proto-Oncogene Proteins A-raf/*metabolism , Proto-Oncogene Proteins B-raf/*metabolism , Proto-Oncogene Proteins c-raf/*metabolism, 14-3-3 Proteins/genetics ; 14-3-3 Proteins/metabolism ; Animals ; Humans ; Mitogen-Activated Protein Kinases/genetics ; Phosphorylation ; Protein Binding ; Proto-Oncogene Proteins A-raf/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins c-raf/genetics

المؤلفون: Zhang XY; Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China., Guo H; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China; The First People's Hospital of Yunnan Province, 157 Jinbi Road, Kunming 650032, China., Han B; Institute of Biomedical Sciences, Minhang hospital, Fudan University, 170 Xinsong Road, Shanghai 201199, China., Zhang XM; State Key Laboratory of Genetic Engineering, Department of Biochemistry, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai 200433, China., Huang Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China., Yang Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China., Liu Y; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China., Guo XX; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China., Hao Q; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China., An S; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China. Electronic address: aslxj@mail.ustc.edu.cn., Xu TR; Faculty of Life Science and Technology, Kunming University of Science and Technology, 727 Jingming South Road, Kunming 650500, China. Electronic address: tianruixu@kmust.edu.cn.

المصدر: Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2018 Aug; Vol. 1866 (8), pp. 849-856. Date of Electronic Publication: 2018 May 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731734 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1570-9639 (Print) Linking ISSN: 15709639 NLM ISO Abbreviation: Biochim Biophys Acta Proteins Proteom Subsets: MEDLINE

مواضيع طبية MeSH: Proteomics*, Proto-Oncogene Proteins A-raf/*metabolism, Apoptosis ; Blotting, Western ; Carcinogenesis/genetics ; Cell Adhesion ; GTP Phosphohydrolases/metabolism ; HEK293 Cells ; Humans ; Immunoprecipitation ; Protein Interaction Domains and Motifs ; Proto-Oncogene Proteins A-raf/genetics ; RNA/metabolism ; Signal Transduction

المؤلفون: Yu, Nina, Raslan, Osama, Lee, Han, Theeler, Brett, Raafat, Tarek, Fragoso, Ruben, Shahlaie, Kiarash, Aboud, Orwa

المصدر: CNS Oncology. 13(1)

مصطلحات موضوعية: BRAF inhibitors, BRAF mutation, MEK inhibitors, brain tumor, craniopharyngioma, Male, Humans, Middle Aged, Vemurafenib, Craniopharyngioma, Proto-Oncogene Proteins B-raf, Pituitary Neoplasms, Mutation, Azetidines, Piperidines

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/04f11460
https://escholarship.org/content/qt04f11460/qt04f11460.pdf

المؤلفون: Ranjpour M; Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India., Katare DP; Proteomics & Translational Research Lab, Centre for Medical Biotechnology, Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India., Wajid S; Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India., Jain SK; Departments of Medical Biochemistry, HIMSR, Jamia Hamdard, New Delhi 110062, India.

المصدر: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2018; Vol. 18 (8), pp. 1163-1176.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101265649 Publication Model: Print Cited Medium: Internet ISSN: 1875-5992 (Electronic) Linking ISSN: 18715206 NLM ISO Abbreviation: Anticancer Agents Med Chem

مواضيع طبية MeSH: Computational Biology* , Protein Interaction Maps*, Carcinoma, Hepatocellular/*metabolism , ErbB Receptors/*metabolism , Liver Neoplasms/*metabolism , Prealbumin/*metabolism , Proto-Oncogene Proteins A-raf/*metabolism, Animals ; Carcinoma, Hepatocellular/chemically induced ; Carcinoma, Hepatocellular/pathology ; Diethylnitrosamine ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; ErbB Receptors/analysis ; Liver Neoplasms/chemically induced ; Liver Neoplasms/pathology ; Male ; Molecular Structure ; Prealbumin/analysis ; Proto-Oncogene Proteins A-raf/analysis ; Rats, Wistar ; Structure-Activity Relationship

المؤلفون: Rauch J; Systems Biology Ireland, University College Dublin, Dublin, Ireland., Vandamme D; Systems Biology Ireland, University College Dublin, Dublin, Ireland., Mack B; Clinical Cooperation Group Molecular Oncology, Department of Head and Neck Research, Ludwig-Maximilians-Universität München, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany., McCann B; Systems Biology Ireland, University College Dublin, Dublin, Ireland., Volinsky N; Systems Biology Ireland, University College Dublin, Dublin, Ireland., Blanco A; Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin, Ireland., Gires O; Clinical Cooperation Group Molecular Oncology, Department of Head and Neck Research, Ludwig-Maximilians-Universität München, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany., Kolch W; Systems Biology Ireland, University College Dublin, Dublin, Ireland.; Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin, Ireland.; School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland.

المصدر: Cell death and differentiation [Cell Death Differ] 2016 Aug; Vol. 23 (8), pp. 1283-95. Date of Electronic Publication: 2016 Feb 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis* , Cell Differentiation*/drug effects, Protein Serine-Threonine Kinases/*metabolism , Proto-Oncogene Proteins A-raf/*metabolism, Caspase 8/metabolism ; Cell Membrane/metabolism ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; MCF-7 Cells ; Microscopy, Fluorescence ; Mitochondria/metabolism ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Neuregulin-1/pharmacology ; Proto-Oncogene Proteins A-raf/antagonists & inhibitors ; Proto-Oncogene Proteins A-raf/genetics ; RNA Interference ; RNA, Small Interfering/metabolism ; Serine-Threonine Kinase 3