المؤلفون: Noura M; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan., Tomita S; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan., Yasuda T; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan., Tsuzuki S; Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Japan., Kiyoi H; Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Hayakawa F; Division of Cellular and Genetic Sciences, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.

المصدر: Cancer medicine [Cancer Med] 2024 Jul; Vol. 13 (13), pp. e7445.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-pim-1*/genetics , Proto-Oncogene Proteins c-pim-1*/metabolism , Cell Transformation, Neoplastic*/genetics , Cell Transformation, Neoplastic*/metabolism , Nuclear Pore Complex Proteins*/genetics , Nuclear Pore Complex Proteins*/metabolism , Oncogene Proteins, Fusion*/genetics , Oncogene Proteins, Fusion*/metabolism, Humans ; Animals ; Mice ; Jurkat Cells ; Up-Regulation ; NIH 3T3 Cells ; Proto-Oncogene Mas ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Apoptosis ; Cell Proliferation

المؤلفون: Yun Y; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China., Wang M; State Key Laboratory of Drug Research, National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Guo S; State Key Laboratory of Drug Research, National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Xie X; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.; State Key Laboratory of Drug Research, National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2024 Jun 18; Vol. 29 (12). Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Gene Editing*/methods , CRISPR-Cas Systems* , Proto-Oncogene Proteins c-pim-1*/antagonists & inhibitors , Proto-Oncogene Proteins c-pim-1*/genetics , Proto-Oncogene Proteins c-pim-1*/metabolism , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry, Animals ; Mice ; Topoisomerase Inhibitors/pharmacology ; Humans ; Recombinational DNA Repair/drug effects ; Gene Knock-In Techniques

المؤلفون: Gao X; School of Clinical Medicine, Anhui Medical College, Hefei 230031, Anhui Province, China.E-mail: 1936521178@qq.com., Chu LJ; School of Clinical Medicine, Anhui Medical College, Hefei 230031, Anhui Province, China., Yan ZH; Department of Hematology, Chaohu Hospital Affiliated to Anhui Medical University, Hefei 238000, Anhui Province, China.

المصدر: Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2024 Jun; Vol. 32 (3), pp. 663-669.

نوع المنشور: English Abstract; Journal Article

بيانات الدورية: Publisher: Zhongguo shi yan xue za zhi she Country of Publication: China NLM ID: 101084424 Publication Model: Print Cited Medium: Print ISSN: 1009-2137 (Print) Linking ISSN: 10092137 NLM ISO Abbreviation: Zhongguo Shi Yan Xue Ye Xue Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Janus Kinase 2*/metabolism , Proto-Oncogene Proteins c-pim-1*/metabolism , Proto-Oncogene Proteins c-pim-1*/genetics , STAT3 Transcription Factor*/metabolism , Cell Proliferation* , Apoptosis* , Signal Transduction* , Leukemia, Myeloid, Acute*/genetics, Humans ; U937 Cells

المؤلفون: Hochban PMM; Institut für Pharmazeutische Chemie, Zentrum für Tumor und Immunbiologie, Philipps-Universität Marburg, Marburg, Germany., Heyder L; Institut für Pharmazeutische Chemie, Zentrum für Tumor und Immunbiologie, Philipps-Universität Marburg, Marburg, Germany., Heine A; Institut für Pharmazeutische Chemie, Philipps-Universität Marburg, Marburg, Germany., Diederich WE; Institut für Pharmazeutische Chemie, Zentrum für Tumor und Immunbiologie, Philipps-Universität Marburg, Marburg, Germany.

المصدر: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Jun; Vol. 357 (6), pp. e2400094. Date of Electronic Publication: 2024 Apr 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

مواضيع طبية MeSH: Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/chemical synthesis , Proto-Oncogene Proteins c-pim-1*/antagonists & inhibitors , Proto-Oncogene Proteins c-pim-1*/metabolism , Stilbenes*/chemistry , Stilbenes*/pharmacology , Stilbenes*/chemical synthesis, Humans ; Binding Sites ; Crystallography, X-Ray ; Drug Design ; Ligands ; Models, Molecular ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship

المؤلفون: Glitscher M; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany., Benz NI; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany., Sabino C; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany., Murra RO; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany., Hein S; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany., Zahn T; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany., Mhedhbi I; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany., Stefanova D; Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Otto-Stern-Weg 7, 8093, Zurich, Switzerland., Bender D; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany., Werner S; Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Otto-Stern-Weg 7, 8093, Zurich, Switzerland., Hildt E; Department of Virology, Paul-Ehrlich-Institute, Paul-Ehrlich-Straße 51-59, D63225, Langen, Germany. Electronic address: eberhard.hildt@pei.de.

المصدر: Antiviral research [Antiviral Res] 2024 Jun; Vol. 226, pp. 105891. Date of Electronic Publication: 2024 Apr 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate*/drug effects , Antiviral Agents*/pharmacology , TOR Serine-Threonine Kinases*/metabolism , Proto-Oncogene Proteins c-pim-1*/antagonists & inhibitors , Proto-Oncogene Proteins c-pim-1*/metabolism , SARS-CoV-2*/drug effects , SARS-CoV-2*/immunology , Proto-Oncogene Proteins c-akt*/metabolism , Signal Transduction*/drug effects, Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Lysosomes/drug effects ; Lysosomes/metabolism ; Zika Virus/drug effects ; Protein Kinase Inhibitors/pharmacology ; Animals ; Hepatitis B virus/drug effects ; Endosomes/drug effects ; Endosomes/metabolism ; Cell Line ; COVID-19/immunology ; COVID-19/virology ; COVID-19 Drug Treatment ; Virus Replication/drug effects ; Biphenyl Compounds ; Thiazolidines

المؤلفون: Xu Q; Key Laboratory of Head & Neck Cancer Translation Research of Zhejiang Province, Zhejiang Cancer Hospital, Hangzhou, China; Postgraduate training base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, China., Wang J; Key Laboratory of Head & Neck Cancer Translation Research of Zhejiang Province, Zhejiang Cancer Hospital, Hangzhou, China; Postgraduate training base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, China., Mao Y; Key Laboratory of Head & Neck Cancer Translation Research of Zhejiang Province, Zhejiang Cancer Hospital, Hangzhou, China; Postgraduate training base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, China., Xuan Z; Key Laboratory of Head & Neck Cancer Translation Research of Zhejiang Province, Zhejiang Cancer Hospital, Hangzhou, China; Postgraduate training base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, China., Yang K; Key Laboratory of Head & Neck Cancer Translation Research of Zhejiang Province, Zhejiang Cancer Hospital, Hangzhou, China., Tang X; Key Laboratory of Head & Neck Cancer Translation Research of Zhejiang Province, Zhejiang Cancer Hospital, Hangzhou, China., Zhu X; Key Laboratory of Head & Neck Cancer Translation Research of Zhejiang Province, Zhejiang Cancer Hospital, Hangzhou, China; Postgraduate training base Alliance of Wenzhou Medical University (Zhejiang Cancer Hospital), Hangzhou, 310022, China. Electronic address: zhuxin@zjcc.org.cn.

المصدر: Neoplasia (New York, N.Y.) [Neoplasia] 2024 Jun; Vol. 52, pp. 100996. Date of Electronic Publication: 2024 Apr 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5586 (Electronic) Linking ISSN: 14765586 NLM ISO Abbreviation: Neoplasia Subsets: MEDLINE

مواضيع طبية MeSH: Drug Synergism* , Proto-Oncogene Proteins B-raf*/genetics , Proto-Oncogene Proteins c-pim-1*/genetics , Proto-Oncogene Proteins c-pim-1*/metabolism , Proto-Oncogene Proteins c-pim-1*/antagonists & inhibitors , Thyroid Cancer, Papillary*/genetics , Thyroid Cancer, Papillary*/drug therapy , Thyroid Cancer, Papillary*/pathology , Thyroid Cancer, Papillary*/metabolism , Thyroid Neoplasms*/genetics , Thyroid Neoplasms*/drug therapy , Thyroid Neoplasms*/metabolism , Thyroid Neoplasms*/pathology, Animals ; Humans ; Mice ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cell Line, Tumor ; Disease Models, Animal ; Gene Expression Regulation, Neoplastic/drug effects ; Mutation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Xenograft Model Antitumor Assays

المؤلفون: Rout AK; Rani Lakshmi Bai Central Agricultural University, Jhansi-284003, Uttar Pradesh, India., Dehury B; Department of Bioinformatics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal-576104, India., Parida SN; Rani Lakshmi Bai Central Agricultural University, Jhansi-284003, Uttar Pradesh, India., Rout SS; Department of Zoology, Fakir Mohan University, Balasore-756089, Odisha, India., Jena R; Department of Zoology, Fakir Mohan University, Balasore-756089, Odisha, India., Kaushik N; Department of Biotechnology, The University of Suwon, Hwaseong si, South Korea., Kaushik NK; Plasma Bioscience Research Center, Kwangwoon University, Seoul 01897, South Korea., Pradhan SK; Department of Bioinformatics, Odisha University of Agriculture and Technology, Bhubaneswar-751003, Odisha, India., Sahoo CR; ICMR-Regional Medical Research Centre, Department of Health Research, Ministry of Health and Family Welfare, Government of India, Bhubaneswar-751023, India., Singh AK; Rani Lakshmi Bai Central Agricultural University, Jhansi-284003, Uttar Pradesh, India., Arya M; Rani Lakshmi Bai Central Agricultural University, Jhansi-284003, Uttar Pradesh, India. Electronic address: meenakshirlbcau@gmail.com., Behera BK; Rani Lakshmi Bai Central Agricultural University, Jhansi-284003, Uttar Pradesh, India. Electronic address: beherabk18@yahoo.co.in.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Jun; Vol. 270 (Pt 1), pp. 132030. Date of Electronic Publication: 2024 May 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-pim-1*/metabolism , Proto-Oncogene Proteins c-pim-1*/antagonists & inhibitors , Proto-Oncogene Proteins c-pim-1*/chemistry , Signal Transduction*/drug effects , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry, Humans ; Animals ; Structure-Activity Relationship ; Neoplasms/drug therapy ; Neoplasms/enzymology ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/therapeutic use ; Molecular Targeted Therapy

المؤلفون: Sharma A; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, India., Dubey R; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, India., Gupta S; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, India., Asati V; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, India., Kumar V; Department of Pharmaceutical Chemistry, Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), Delhi Pharmaceutical Sciences and Research University, India., Kumar D; Department of Pharmaceutical Chemistry, Poona College of Pharmacy, Bharati Vidyapeeth University, Pune, India., Mahapatra DK; Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India., Jaiswal M; Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India., Jain SK; Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India., Bharti SK; Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India.

المصدر: Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2024 May; Vol. 34 (5), pp. 365-382. Date of Electronic Publication: 2024 Jun 13.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE

مواضيع طبية MeSH: Patents as Topic* , Protein Kinase Inhibitors*/pharmacology , Proto-Oncogene Proteins c-pim-1*/antagonists & inhibitors , Proto-Oncogene Proteins c-pim-1*/metabolism , Antineoplastic Agents*/pharmacology , Neoplasms*/drug therapy , Neoplasms*/pathology , Neoplasms*/enzymology, Humans ; Animals ; Proto-Oncogene Proteins/antagonists & inhibitors ; Proto-Oncogene Proteins/metabolism ; Hematologic Neoplasms/drug therapy ; Hematologic Neoplasms/pathology ; Molecular Targeted Therapy ; Drug Development ; Drug Design ; Protein Serine-Threonine Kinases

المؤلفون: Yang K; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Yu X; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Guo Z; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Fang Z; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Zhang H; Department of Neurosurgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Zhang W; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Liu C; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Ji Y; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Dong Z; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Gu Q; Department of Neurosurgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Yao J; Department of Neurosurgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China., Liu C; Department of General Surgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China. Electronic address: 600509@hrbmu.edu.cn.

المصدر: Life sciences [Life Sci] 2024 Jul 15; Vol. 349, pp. 122714. Date of Electronic Publication: 2024 May 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-pim-1*/metabolism , Non-alcoholic Fatty Liver Disease*/metabolism , Oxidative Stress* , NF-E2-Related Factor 2*/metabolism , Mice, Inbred C57BL* , NAD(P)H Dehydrogenase (Quinone)*/metabolism , NAD(P)H Dehydrogenase (Quinone)*/genetics , Heme Oxygenase-1*/metabolism, Animals ; Male ; Mice ; Diet, High-Fat/adverse effects ; Liver/metabolism ; Liver/pathology ; Signal Transduction ; Apoptosis ; Membrane Proteins/metabolism ; Membrane Proteins/genetics

المؤلفون: Julson JR; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Quinn CH; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Nazam N; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Bownes LV; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Stewart JE; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA., Beierle EA; Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA. Electronic address: elizabeth.beierle@childrensal.org.

المصدر: Journal of pediatric surgery [J Pediatr Surg] 2024 Jul; Vol. 59 (7), pp. 1334-1341. Date of Electronic Publication: 2024 Mar 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Saunders Country of Publication: United States NLM ID: 0052631 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-5037 (Electronic) Linking ISSN: 00223468 NLM ISO Abbreviation: J Pediatr Surg Subsets: MEDLINE

مواضيع طبية MeSH: Neuroblastoma*/drug therapy , Neuroblastoma*/pathology , Neuroblastoma*/genetics , Doxorubicin*/pharmacology , Doxorubicin*/therapeutic use , Proto-Oncogene Proteins c-pim-1*/antagonists & inhibitors , Drug Resistance, Neoplasm* , Multidrug Resistance-Associated Proteins*/genetics , Multidrug Resistance-Associated Proteins*/metabolism, Humans ; Cell Line, Tumor ; Antibiotics, Antineoplastic/therapeutic use ; Antibiotics, Antineoplastic/pharmacology ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Protein Serine-Threonine Kinases/metabolism ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Drug Synergism ; Biphenyl Compounds ; Thiazolidines