المؤلفون: Onur Cil, Puay-Wah Phuan, Sujin Lee, Joseph Tan, Peter M. Haggie, Marc H. Levin, Liang Sun, Jay R. Thiagarajah, Tonghui Ma, Alan S. Verkman

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 3, Pp 317-327 (2016)

مصطلحات موضوعية: Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X16000072; https://doaj.org/toc/2352-345X

URL الوصول: https://doaj.org/article/e1ed29e354e3480ab8fec86c297f2023

المؤلفون: Lukmanee Tradtrantip, Nithi Asavapanumas, Puay-Wah Phuan, A S Verkman

المصدر: PLoS ONE, Vol 9, Iss 9, p e106824 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4156393?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/83f3d25240314191980d6571390a9f9d

المؤلفون: Misol Ahn, Sina Ghaemmaghami, Yong Huang, Puay-Wah Phuan, Barnaby C H May, Kurt Giles, Stephen J DeArmond, Stanley B Prusiner

المصدر: PLoS ONE, Vol 7, Iss 7, p e39112 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3388068?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/b1378581b9864925bf5d24e3b527f0f3

المؤلفون: Mark J. Kurth, Peter M. Haggie, Marina E. Shatskikh, Julia Y. Lu, Jung-Ho Son, Alan S. Verkman, Amber A. Rivera, Joseph-Anthony Tan, Jie S. Zhu, Puay-Wah Phuan

المصدر: Bioorganic & medicinal chemistry letters, vol 29, iss 16
Bioorg Med Chem Lett

مصطلحات موضوعية: Pyridines, Chronic rhinosinusitis, Antiporter, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, 01 natural sciences, Biochemistry, Cystic fibrosis, Mice, Regioselectivity, Drug Discovery, Lung, Inbred F344, Anion transporter, Molecular Structure, biology, Ion exchange, Chemistry, Pharmacology and Pharmaceutical Sciences, Transmembrane protein, Sulfate Transporters, 5.1 Pharmaceuticals, Respiratory, Molecular Medicine, Development of treatments and therapeutic interventions, Medicinal & Biomolecular Chemistry, Article, Small Molecule Libraries, Structure-Activity Relationship, Medicinal and Biomolecular Chemistry, Downregulation and upregulation, SLC26A4, otorhinolaryngologic diseases, medicine, Animals, Pendrin, Hydrazine (antidepressant), Molecular Biology, 010405 organic chemistry, Organic Chemistry, medicine.disease, Rats, Inbred F344, Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Pyrazole, biology.protein, Pyrazoles

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5b365bb1f538164643be9aacb68beb
https://doi.org/10.1016/j.bmcl.2019.07.003

المؤلفون: Peter M. Haggie, Walter E. Finkbeiner, Joseph-Anthony Tan, Alan S. Verkman, Dennis W. Nielson, Jung-Ho Son, Luis J. V. Galietta, Mark J. Kurth, Lorna Zlock, Puay-Wah Phuan, Ilaria Musante, Clarabella J. Li

المساهمون: Phuan, Puay-Wah, Son, Jung-Ho, Tan, Joseph-Anthony, Li, Clarabella, Musante, Ilaria, Zlock, Lorna, Nielson, Dennis W., Finkbeiner, Walter E., Kurth, Mark J., Galietta, Luis J., Haggie, Peter M., Verkman, Alan S.

المصدر: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, vol 17, iss 5

مصطلحات موضوعية: 0301 basic medicine, Cystic Fibrosis, High-throughput screen, Respiratory System, Mutant, Cystic Fibrosis Transmembrane Conductance Regulator, Quinolones, Pharmacology, Aminophenols, medicine.disease_cause, Cystic fibrosis, Congenital, 0302 clinical medicine, CFTR, Lung, Sulfonamides, Mutation, Cultured, Drug Synergism, respiratory system, Small molecule, Potentiator, Cystic fibrosi, N1303K, Ion Channel Gating, Pulmonary and Respiratory Medicine, Agonist, congenital, hereditary, and neonatal diseases and abnormalities, medicine.drug_class, Cells, Clinical Sciences, Article, Cell Line, Structure-Activity Relationship, 03 medical and health sciences, Rare Diseases, medicine, Animals, Humans, Structure–activity relationship, business.industry, medicine.disease, 030104 developmental biology, 030228 respiratory system, Cell culture, Pediatrics, Perinatology and Child Health, Mutant Proteins, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff281dd2963975887cc2ef3535c3e964
https://doi.org/10.1016/j.jcf.2018.05.010

المؤلفون: Puay-Wah Phuan, Alan S. Verkman, Jie S. Zhu, Jung-Ho Son, Ka Yi Tsui, Peter M. Haggie, Soren Lipman, Mark J. Kurth, Amy Cheung, Dean J. Tantillo

المصدر: Eur J Med Chem

مصطلحات موضوعية: Models, Molecular, Indoles, Cystic Fibrosis, Mutant, Cystic Fibrosis Transmembrane Conductance Regulator, Quinolones, Aminophenols, 01 natural sciences, chemistry.chemical_compound, Piperidines, Models, Drug Discovery, CFTR, Chloride Channel Agonists, Lung, 0303 health sciences, biology, Chemistry, c.3700A>G, General Medicine, Pharmacology and Pharmaceutical Sciences, Small molecule, Cystic fibrosis transmembrane conductance regulator, Potentiator, Piperidine, Stereochemistry, Medicinal & Biomolecular Chemistry, Modulator, Article, Cell Line, 03 medical and health sciences, Structure-Activity Relationship, Medicinal and Biomolecular Chemistry, Rare Diseases, Potency, Animals, Humans, 030304 developmental biology, Pharmacology, Indole test, 010405 organic chemistry, Organic Chemistry, Molecular, N1303K-CFTR, 0104 chemical sciences, Rats, Mutation, biology.protein, c.3700A > G, Function (biology)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957bd2600c5dd46874441017af9e5bc3
https://escholarship.org/uc/item/2jt1m0z8

المؤلفون: Lukmanee Tradtrantip, Puay-Wah Phuan, Alan S. Verkman, Tianjiao Duan, Jeffrey Bennett

المصدر: Neuropharmacology

مصطلحات موضوعية: 0301 basic medicine, Serum, Antibody Affinity, Autoimmunity, medicine.disease_cause, 0302 clinical medicine, Competitive, Immunologic, Monoclonal, Killer Cells, 2.1 Biological and endogenous factors, Psychology, Aetiology, Cytotoxicity, Cytotoxicity Tests, Antibody-dependent cell-mediated cytotoxicity, biology, Chemistry, Neuromyelitis Optica, Antibodies, Monoclonal, Pharmacology and Pharmaceutical Sciences, Recombinant Proteins, Killer Cells, Natural, Blocking, Natural, Antibody, Astrocyte, Biotechnology, Cell Survival, NMOSD, CHO Cells, Binding, Competitive, Autoimmune Disease, Article, Antibodies, Affinity maturation, 03 medical and health sciences, Cellular and Molecular Neuroscience, Cricetulus, Blocking antibody, medicine, Animals, Humans, Antibodies, Blocking, Eye Disease and Disorders of Vision, Autoantibodies, Pharmacology, Aquaporin 4, Neurology & Neurosurgery, Autoantibody, Antibody-Dependent Cell Cytotoxicity, Neurosciences, Complement System Proteins, Binding, Cytotoxicity Tests, Immunologic, AQP4, 030104 developmental biology, Mutagenesis, Immunoglobulin G, Immunology, biology.protein, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defddbc39525727084cff39762b331ff
https://escholarship.org/uc/item/4s64g6bg

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المؤلفون: Elena Diez-Cecilia, Luis J. V. Galietta, Sujin Lee, Puay-Wah Phuan, Onur Cil, Sarah E Levy, Marc O. Anderson, Loretta Ferrera, Amanda L. Reggi, Alannah C Moises, Alan S. Verkman, Eric C. Truong

المساهمون: Truong, Eric C., Phuan, Puay W., Reggi, Amanda L., Ferrera, Loretta, Galietta, Luis J. V., Levy, Sarah E., Moises, Alannah C., Cil, Onur, Diez-Cecilia, Elena, Lee, Sujin, Verkman, Alan S., Anderson, Marc O.

المصدر: Journal of Medicinal Chemistry. 60:4626-4635

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Chloride Channel, Carboxylic acid, Carboxylic Acids, chemistry.chemical_element, Thiophenes, Calcium, Article, ANO1, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Chloride Channels, Thiophene, Drug Discovery, Animals, Humans, Structure–activity relationship, Anoctamin-1, Cells, Cultured, chemistry.chemical_classification, biology, Animal, Chemistry, Drug Discovery3003 Pharmaceutical Science, Rats, Inbred F344, Transmembrane protein, Rats, 030104 developmental biology, Biochemistry, Chloride channel, biology.protein, Rat, Molecular Medicine, Carboxylic Acid, Human

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b691ef009cb957673a0f23c46b0d57
https://doi.org/10.1021/acs.jmedchem.7b00020

المؤلفون: Nicholas C. Zachos, Puay Wah Phuan, Ruxian Lin, Anne Marie Gillespie, Alan S. Verkman, Lukmanee Tradtrantip, Sujin Lee, Ming Tse, Onur Cil, Mark Donowitz, Jianyi Yin

المصدر: The FASEB Journal. 31:751-760

مصطلحات موضوعية: Diarrhea, 0301 basic medicine, Enterocyte, Cystic Fibrosis Transmembrane Conductance Regulator, Pyrimidinones, Pharmacology, medicine.disease_cause, Biochemistry, Microbiology, Mice, 03 medical and health sciences, 0302 clinical medicine, Oxazines, Genetics, medicine, Animals, Humans, Pyrroles, Secretion, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Toxin, Research, Cholera toxin, medicine.disease, Cholera, Cystic fibrosis transmembrane conductance regulator, Small intestine, Intestines, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Chloride channel, biology.protein, Female, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07a6371389ee049ae20c440b554e411
https://doi.org/10.1096/fj.201600891r