المؤلفون: Langguth, Miriam, Maranou, Eleftheria, Koskela, Saara A., Elenius, Oskar, Kallionpää, Roosa E., Birkman, Eva-Maria, Pulkkinen, Otto I., Sundvall, Maria^{Aff4, Aff5}, Salmi, Marko^{Aff6, Aff7, Aff8}, Figueiredo, Carlos R.^{Aff1, Aff4, Aff6, Aff9, IDs41435024002747_cor10}

المصدر: Genes & Immunity. 25(3):188-200

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المؤلفون: Tianduanyi Wang, Pulkkinen, Otto I., Aittokallio, Tero

المصدر: Frontiers in Pharmacology; 9/26/2022, Vol. 13, p01-16, 16p

مصطلحات موضوعية: DRUG discovery, DRUG repositioning, DRUG development, KINASE inhibitors, MISSING data (Statistics)

المؤلفون: Pulkkinen, Otto I., Gautam, Prson, Mustonen, Ville, Aittokallio, Tero Antero

المصدر: Pulkkinen, Otto I. Gautam, Prson Mustonen, Ville Aittokallio, Tero Antero . Multiobjective optimization identifies cancer-selective combination therapies. PLoS Computational Biology. 2020, 16(12)
PLoS Computational Biology

الإتاحة: http://hdl.handle.net/10852/83896
https://www.duo.uio.no/bitstream/handle/10852/83896/2/journal.pcbi.1008538.pdf

المؤلفون: Pulkkinen OI; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Helsinki Institute for Information Technology (HIIT), Department of Computer Science, University of Helsinki, Helsinki, Finland.; Computational Physics Laboratory, Tampere University, Tampere, Finland.; Department of Mathematics and Statistics, University of Turku, Turku, Finland., Gautam P; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Mustonen V; Helsinki Institute for Information Technology (HIIT), Department of Computer Science, University of Helsinki, Helsinki, Finland.; Organismal and Evolutionary Biology Research Programme, Institute of Biotechnology, University of Helsinki, Helsinki, Finland., Aittokallio T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Department of Mathematics and Statistics, University of Turku, Turku, Finland.; Institute for Cancer Research, Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway.; Oslo Centre for Biostatistics and Epidemiology (OCBE), Faculty of Medicine, University of Oslo, Oslo, Norway.

المصدر: PLoS computational biology [PLoS Comput Biol] 2020 Dec 28; Vol. 16 (12), pp. e1008538. Date of Electronic Publication: 2020 Dec 28 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

مواضيع طبية MeSH: Melanoma/*drug therapy , Skin Neoplasms/*drug therapy, Antineoplastic Agents/therapeutic use ; Combined Modality Therapy ; Humans ; Precision Medicine ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins B-raf/metabolism