المؤلفون: Kerkelä, Risto, Grazette, Luanda, Yacobi, Rinat, Iliescu, Cezar, Patten, Richard, Beahm, Cara, Walters, Brian, Shevtsov, Sergei, Pesant, Stéphanie, Clubb, Fred J, Rosenzweig, Anthony, Salomon, Robert N, Van Etten, Richard A, Alroy, Joseph, Durand, Jean-Bernard, Force, Thomas

المصدر: Nature medicine. 12(8)

مصطلحات موضوعية: Adenosine Triphosphatases: analysis, metabolism, Animals, Antineoplastic Agents: administration & dosage, adverse effects, pharmacology, toxicity, Benzamides, Calcium: metabolism, Cell Death: drug effects, Cell Membrane Permeability: drug effects, Cells, Cultured, Cytochromes c: secretion, Dose-Response Relationship, Drug, Echocardiography, Heart Failure: chemically induced, pathology, Humans, Injections, Intraperitoneal, Membrane Potentials: drug effects, Mice, Mice, Inbred C57BL, Mitochondria, Heart: drug effects, pathology, ultrastructure, Mitochondrial Membranes: drug effects, Myocytes, Cardiac: drug effects, pathology, ultrastructure, Piperazines: administration & dosage, adverse effects, pharmacology, toxicity, Pyrimidines: administration & dosage, adverse effects, pharmacology, toxicity, Sarcoplasmic Reticulum: drug effects, pathology, ultrastructure, Severity of Illness Index, Time Factors, Ventricular Dysfunction, Left: chemically induced, physiopathology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/34r245fh

المؤلفون: Rezende, Vinícius Marcondes, Rivellis, Ariane Julio, Gomes, Melissa Medrano, Dörr, Felipe Augusto, Novaes, Mafalda Megumi Yoshinaga, Nardinelli, Luciana, Costa, Ariel Lais de Lima, Chamone, Dalton de Alencar Fisher, Bendit, Israel

المصدر: Revista Brasileira de Hematologia e Hemoterapia. January 2013 35(2)

مصطلحات موضوعية: Leukemia, myelogenous, chronic, BCR-ABL positive, Mass spectrometry, Chromatography, high pressure liquid, Pyrimidines/administration & dosage, Antineoplastic agents/administration & dosage, Therapeutic drug monitoring

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842013000200011

المؤلفون: Patricia N. Sidharta, Pierre Gueneau de Mussy, Marc Iglarz, Nicolas Guérard, Michel Burnier, Jasper Dingemanse, Grégoire Wuerzner, Marc Maillard, Bruno Flamion

المصدر: Clinical pharmacology and therapeutics, vol. 109, no. 3, pp. 746-753
Clinical Pharmacology and Therapeutics

مصطلحات موضوعية: Adult, Endothelin Receptor Antagonists, Male, medicine.medical_specialty, Administration, Oral, Natriuresis, Placebo, Weight Gain, 030226 pharmacology & pharmacy, Article, Excretion, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Body Water, Double-Blind Method, Internal medicine, Edema, medicine, Homeostasis, Humans, Pharmacology (medical), Aldosterone, Aldosterone/blood, Body Water/metabolism, Cross-Over Studies, Endothelin Receptor Antagonists/administration & dosage, Endothelin Receptor Antagonists/adverse effects, Glycopeptides/blood, Healthy Volunteers, Middle Aged, Natriuresis/drug effects, Pyrimidines/administration & dosage, Pyrimidines/adverse effects, Sodium, Dietary/adverse effects, Sulfonamides/administration & dosage, Sulfonamides/adverse effects, Switzerland, Uric Acid/blood, Water-Electrolyte Balance/drug effects, Weight Gain/drug effects, Pharmacology, Sulfonamides, Endothelin receptor antagonist, business.industry, Research, Glycopeptides, Sodium, Dietary, Articles, Water-Electrolyte Balance, Crossover study, Uric Acid, Endocrinology, Pyrimidines, chemistry, 030220 oncology & carcinogenesis, Uric acid, Hemoglobin, medicine.symptom, business, Weight gain

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a2c9329d030e44abc38075c4315ced
https://serval.unil.ch/notice/serval:BIB_1BE20415C0D5

المؤلفون: Baranello, Giovanni, Darras, Basil T., Day, John W., Deconinck, Nicolas, Klein, Andrea, Masson, Riccardo, Mercuri, Eugenio, Rose, Kristy, El-Khairi, Muna, Gerber, Marianne, Gorni, Ksenija, Khwaja, Omar, Kletzl, Heidemarie, Scalco, Renata S., Seabrook, Timothy, Fontoura, Paulo, Servais, Laurent

المصدر: The New England journal of medicine, 384 (10), 915-923 (2021-03)

مصطلحات موضوعية: Administration, Oral, Azo Compounds/administration & dosage/adverse effects/pharmacokinetics, Dose-Response Relationship, Drug, Female, Humans, Infant, Male, Neuromuscular Agents/administration & dosage/adverse effects/pharmacokinetics, Progression-Free Survival, Pyrimidines/administration & dosage/adverse effects/pharmacokinetics, RNA Splicing, Respiratory Insufficiency/etiology, Respiratory Tract Infections/etiology, Spinal Muscular Atrophies of Childhood/complications/drug therapy/mortality, Survival of Motor Neuron 1 Protein/blood/genetics, Human health sciences, Pediatrics, Neurology, Sciences de la santé humaine, Pédiatrie, Neurologie

Relation: urn:issn:0028-4793; urn:issn:1533-4406

URL الوصول: https://orbi.uliege.be/handle/2268/268491

المؤلفون: Catherine Jane Bale, Rachel Butler, S Waters, Angela C. Casbard, Sarah Moon, Andrew Foxley, Ramachandran Venkitaraman, Catrin Cox, Johnathan Joffe, Tracie-Ann Madden, Fouad S Alchami, Margherita Carucci, Robert H. Jones, Chris Twelves, Pavel Bezecny, Sacha J Howell

المصدر: Jones, R, Casbard, A, Carucci, M, Cox, C, Butler, R, Alchami, F, Madden, T-A, Bale, C, Bezecny, P, Joffe, J, Moon, S, Twelves, C, Venkitaraman, R, Waters, S, Foxley, A & Howell, S 2020, ' Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION) : a multicentre, randomised, controlled, phase 2 trial ', The Lancet Oncology, vol. 21, no. 3, pp. 345-357 . https://doi.org/10.1016/S1470-2045(19)30817-4

مصطلحات موضوعية: 0301 basic medicine, Fulvestrant/administration & dosage, Drug Resistance, Neoplasm/drug effects, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Antineoplastic Combined Chemotherapy Protocols, Clinical endpoint, Neoplasm Metastasis, Fulvestrant, Aged, 80 and over, Manchester Cancer Research Centre, Aromatase Inhibitors, Hazard ratio, Carcinoma, Ductal, Breast, Middle Aged, Prognosis, Survival Rate, Neoplasm Recurrence, Local/drug therapy, Oncology, Receptors, Estrogen, 030220 oncology & carcinogenesis, Female, Receptors, Estrogen/metabolism, medicine.drug, Adult, medicine.medical_specialty, medicine.drug_class, Breast Neoplasms, Carcinoma, Lobular/drug therapy, Placebo, 03 medical and health sciences, Breast Neoplasms/drug therapy, Double-Blind Method, Internal medicine, medicine, Humans, Neoplasm Invasiveness, Pyrroles, Pyrimidines/administration & dosage, Survival rate, Aged, Salvage Therapy, Aromatase Inhibitors/pharmacology, Intention-to-treat analysis, Aromatase inhibitor, business.industry, Pyrroles/administration & dosage, ResearchInstitutes_Networks_Beacons/mcrc, Carcinoma, Lobular, 030104 developmental biology, Pyrimidines, Carcinoma, Ductal, Breast/drug therapy, Drug Resistance, Neoplasm, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Neoplasm Recurrence, Local, business, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3e1775f72f2c39bba92c189237cd97
https://pubmed.ncbi.nlm.nih.gov/32359499

المؤلفون: Petraitis, Vidmantas, Petraitiene, Ruta, Hope, William W., Meletiadis, Joseph, Mickiene, Diana, Hughes, Johanna E., Cotton, Margaret P., STERGIOPOULOU, Theodouli, Kasai, Miki, Francesconi, Andrea, Schaufele, Robert L., Sein, Tin, Avila, Nilo A., Bacher, John, Walsh, Thomas J.

المصدر: Antimicrobial Agents and Chemotherapy, 53 (6), 2382-91 (2009-06)

مصطلحات موضوعية: Animals, Antifungal Agents/administration & dosage, Area Under Curve, Bronchoalveolar Lavage Fluid/chemistry, Dose-Response Relationship, Drug, Drug Interactions, Drug Therapy, Combination, Echinocandins/administration & dosage/adverse effects/pharmacokinetics, Female, Humans, Mannans/analysis/blood, Pulmonary Aspergillosis/drug therapy/microbiology, Pyrimidines/administration & dosage/adverse effects/pharmacokinetics, Rabbits, Triazoles/administration & dosage/adverse effects/pharmacokinetics, Human health sciences, Pharmacy, pharmacology & toxicology, Immunology & infectious disease, Life sciences, Microbiology, Sciences de la santé humaine, Pharmacie, pharmacologie & toxicologie, Immunologie & maladie infectieuse, Sciences du vivant, Microbiologie

Relation: urn:issn:0066-4804; urn:issn:1098-6596

URL الوصول: https://orbi.uliege.be/handle/2268/249616

المؤلفون: Nicola Dias, R. Karl Malcolm, Vicky L. Kett, Peter Boyd, Brid Devlin, Oliver Hartley, Robin E. Offord, David R. Cameron, John W. McBride

المصدر: McBride, J W, Malcolm, R K, Dias, N, Cameron, D, Offord, R E, Hartley, O, Kett, V L, Devlin, B & Boyd, P 2019, ' Development and pharmacokinetics of a combination vaginal ring for sustained release of dapivirine and the protein microbicide 5P12-RANTES ', International Journal of Pharmaceutics, vol. 564, pp. 207-213 . https://doi.org/10.1016/j.ijpharm.2019.04.040
International Journal of Pharmaceutics, Vol. 564 (2019) pp. 207-213

مصطلحات موضوعية: HIV microbicide, Dapivirine, Human immunodeficiency virus (HIV), Pharmaceutical Science, HIV Infections, 02 engineering and technology, ddc:616.07, Pharmacology, medicine.disease_cause, 030226 pharmacology & pharmacy, 0302 clinical medicine, Medicine, Silicone elastomer, Pyrimidines/administration & dosage/pharmacokinetics, Reverse-transcriptase inhibitor, Combination drug delivery, 021001 nanoscience & nanotechnology, Vaginal ring, Drug Combinations, Chemokines, CC, Drug delivery, Vagina, Female, Chemokines, 0210 nano-technology, Vagina/metabolism, CC/administration & dosage/pharmacokinetics, medicine.drug, Sheep pharmacokinetics, Anti-HIV Agents, Delayed-Action Preparations/administration & dosage, HIV prevention, Anti-HIV Agents/administration & dosage/pharmacokinetics, 03 medical and health sciences, HIV Infections/prevention & control, Pharmacokinetics, SDG 3 - Good Health and Well-being, Microbicide, Animals, Sheep, business.industry, Contraceptive Devices, Female, Antiretroviral, Microbicides for sexually transmitted diseases, Pyrimidines, Delayed-Action Preparations, Contraceptive Devices, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d791bf7ea3d4aa4fd2d902735617c18
https://pure.qub.ac.uk/en/publications/development-and-pharmacokinetics-of-a-combination-vaginal-ring-for-sustained-release-of-dapivirine-and-the-protein-microbicide-5p12rantes(8c64f860-7d87-479d-9a4e-9dcd7318a1ce).html

المؤلفون: Baron, Frédéric, Frere, Pascale, Herens, Christian, Fillet, Georges, Beguin, Yves

المصدر: Haematologica, 87(12), 43. Pavia, Italy: Ferrata Storti Foundation (2002).

مصطلحات موضوعية: Antineoplastic Combined Chemotherapy Protocols/administration & dosage, Combined Modality Therapy, Cytogenetic Analysis, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive/therapy, Male, Middle Aged, Piperazines/administration & dosage, Pyrimidines/administration & dosage, Remission Induction/methods, Stem Cell Transplantation/methods, Vidarabine/administration & dosage/analogs & derivatives, Whole-Body Irradiation, Human health sciences :: Hematology, Sciences de la santé humaine :: Hématologie

URL الوصول: https://orbi.uliege.be/handle/2268/80222

المؤلفون: Baron, Frédéric, Frere, Pascale, Fillet, Georges, Beguin, Yves

المصدر: Haematologica, 86 (9), 993-4 (2001)

مصطلحات موضوعية: Adult, Antineoplastic Agents/administration & dosage, Combined Modality Therapy, Female, Hematopoietic Stem Cell Transplantation, Humans, Leukemia/therapy, Lymphocyte Transfusion, Piperazines/administration & dosage, Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy, Pyrimidines/administration & dosage, Recurrence, Transplantation, Homologous, Treatment Outcome, Human health sciences, Hematology, Sciences de la santé humaine, Hématologie

Relation: urn:issn:0390-6078; urn:issn:1592-8721

URL الوصول: https://orbi.uliege.be/handle/2268/9451

المؤلفون: Chalandon, Yves, Thomas, Xavier, Hayette, Sandrine, Cayuela, Jean-Michel, Abbal, Claire, Huguet, Françoise, Raffoux, Emmanuel, Leguay, Thibaut, Rousselot, Philippe, Lepretre, Stéphane, Escoffre-Barbe, Martine, Maury, Sébastien, Berthon, Céline, Tavernier, Emmanuelle, Lambert, Jean-François, Lafage-Pochitaloff, Marina, Lhéritier, Véronique, Chevret, Sylvie, Ifrah, Norbert, Dombret, Hervé, Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)

المصدر: Blood, Vol. 125, No 24 (2015) pp. 3711-3719

مصطلحات موضوعية: Benzamides / toxicity, Male, Piperazines / administration & dosage, medicine.medical_treatment, Biochemistry, Gastroenterology, Piperazines, Pyrimidines / toxicity, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Medicine, Philadelphia Chromosome, Piperazines / therapeutic use, Protein Kinase Inhibitors / therapeutic use, Piperazines / toxicity, ddc:616, Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy, Protein Kinase Inhibitors / administration & dosage, Antineoplastic Combined Chemotherapy Protocols / toxicity, Hematology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Middle Aged, Pyrimidines / administration & dosage, Treatment Outcome, Benzamides, Imatinib Mesylate, Female, Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy, medicine.drug, Adult, medicine.medical_specialty, Vincristine, Adolescent, Cyclophosphamide, Benzamides / therapeutic use, Immunology, Benzamides / administration & dosage, Disease-Free Survival, Young Adult, Internal medicine, Acute lymphocytic leukemia, Antineoplastic Combined Chemotherapy Protocols / therapeutic use, Pyrimidines / therapeutic use, Humans, Protein Kinase Inhibitors, Protein Kinase Inhibitors / toxicity, Chemotherapy, Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics, business.industry, Imatinib, Cell Biology, Antineoplastic Combined Chemotherapy Protocols / administration & dosage, medicine.disease, Surgery, Transplantation, Regimen, Pyrimidines, Imatinib mesylate, business, Stem Cell Transplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ff7b8fa7c747ce8aaa642d7f259a20
https://doi.org/10.1182/blood-2015-02-627935