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المؤلفون: Arne Schousboe, Rasmus P. Clausen, Stefanie Kickinger, Jonas Skovgaard-Petersen, Maria E. K. Lie, Gerhard F. Ecker, Petrine Wellendorph, H. Steve White
المصدر: Lie, M E K, Kickinger, S, Skovgaard-Petersen, J, Ecker, G F, Clausen, R P, Schousboe, A, White, H S & Wellendorph, P 2020, ' Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects ', Neurochemical Research, vol. 45, pp. 1551–1565 . https://doi.org/10.1007/s11064-020-03017-y
Neurochemical Researchمصطلحات موضوعية: 0301 basic medicine, Male, GABA Plasma Membrane Transport Proteins, Tiagabine, Mice, Transgenic, GABA uptake, CHO Cells, Pharmacology, Biochemistry, Epilepsy, Reflex, Protein Structure, Secondary, GABA transporter 1, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, 0302 clinical medicine, Betaine, Cricetulus, Seizures, medicine, GABA transporter, Animals, Humans, Q299L, Binding site, Original Paper, Epilepsy, biology, General Medicine, Cyclohexanecarboxylic acid, 030104 developmental biology, HEK293 Cells, Treatment Outcome, chemistry, Acoustic Stimulation, GAT1, Docking (molecular), Cell culture, biology.protein, Anticonvulsants, Homology modelling, 030217 neurology & neurosurgery, medicine.drug, Protein Binding
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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be1e5b0f009359dee573c6df3162134
https://curis.ku.dk/portal/da/publications/pharmacological-characterization-of-a-betainegaba-transporter-1-bgt1-inhibitor-displaying-an-unusual-biphasic-inhibition-profile-and-antiseizure-effects(f58627b3-6c59-4d36-ad00-48d86bf6a034).html -
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المصدر: Lie , M E K , Kickinger , S , Skovgaard-Petersen , J , Ecker , G F , Clausen , R P , Schousboe , A , White , H S & Wellendorph , P 2020 , ' Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects ' , Neurochemical Research , vol. 45 , pp. 1551–1565 .
مصطلحات الفهرس: Epilepsy, GABA uptake, GAT1, Homology modelling, Q299L, article