نتائج البحث - "QPX7728"

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دورية أكاديمية

Oral Antibiotics in Clinical Development for Community-Acquired Urinary Tract Infections

المؤلفون: Veeraraghavan, Balaji^{Aff1, IDs40121021005094_cor1}, Bakthavatchalam, Yamuna Devi, Sahni, Rani Diana

المصدر: Infectious Diseases and Therapy. 10(4):1815-1835

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2

دورية أكاديمية

Three new inhibitors of class A β-lactamases evaluated by molecular docking and dynamics simulations methods: relebactam, enmetazobactam, and QPX7728

المؤلفون: Saral Sariyer, Ayşegül^{Aff1, IDs00894022050733_cor1}

المصدر: Journal of Molecular Modeling: Computational Chemistry - Life Science - Advanced Materials - New Methods. 28(4)

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3

دورية أكاديمية

Molecular Basis of Bicyclic Boronate β-Lactamase Inhibitors of Ultrabroad Efficacy – Insights From Molecular Dynamics Simulation Studies

المؤلفون: Emilio Lence, Concepción González-Bello

المصدر: Frontiers in Microbiology, Vol 12 (2021)

مصطلحات موضوعية: boron-based β-lactamase inhibitors, simulations of biomacromolecules, metallo-β-lactamases, serine-β-lactamases, binding mode, QPX7728, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2021.721826/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/48c735e1802e4dd1bf830cfd2e8c396d

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4

دورية أكاديمية

QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics

المؤلفون: Olga Lomovskaya, Ruslan Tsivkovski, Dongxu Sun, Raja Reddy, Maxim Totrov, Scott Hecker, David Griffith, Jeffery Loutit, Michael Dudley

المصدر: Frontiers in Microbiology, Vol 12 (2021)

مصطلحات موضوعية: QPX7728, beta-lactamase inhibitor, carbapenemase, metallo β-lactamase, CRE, Acinetobacter, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2021.697180/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/b2ee9656241b4d9a9d7eaf4c26d8885c

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Oral Antibiotics in Clinical Development for Community-Acquired Urinary Tract Infections

المؤلفون: Yamuna Devi Bakthavatchalam, Balaji Veeraraghavan, Rani Diana Sahni

المصدر: Infectious Diseases and Therapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef0b03d8e4d2f95c79cb8d08f693a70
https://doi.org/10.1007/s40121-021-00509-4

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6

Molecular Basis of Bicyclic Boronate β-Lactamase Inhibitors of Ultrabroad Efficacy – Insights From Molecular Dynamics Simulation Studies

المؤلفون: Concepción González-Bello, Emilio Lence

المصدر: Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e43973f3b9904ef2b8d7a2ec26ddab
https://doi.org/10.3389/fmicb.2021.721826

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QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics

المؤلفون: Scott J. Hecker, Maxim Totrov, Dongxu Sun, Jeffery S. Loutit, Olga Lomovskaya, Raja Reddy, Ruslan Tsivkovski, David A. Griffith, Michael N. Dudley

المصدر: Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56083282633c3ccebe28d9aebab8f1f5
http://europepmc.org/articles/PMC8287861

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In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa

المؤلفون: Debora Rubio-Aparicio, Olga Lomovskaya, Mariana Castanheira, Jeffery S. Loutit, Dongxu Sun, Kirk Nelson, Jill M. Lindley, Ruslan Tsivkovski, Michael N. Dudley

المصدر: Antimicrobial Agents and Chemotherapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0290222a344dd1c50ba5b6008fc88bb9
http://europepmc.org/articles/PMC8315991

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دورية أكاديمية

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Biochemical Characterization of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases

المؤلفون: Ruslan Tsivkovski, Olga Lomovskaya, Maxim Totrov

المصدر: Antimicrobial Agents and Chemotherapy

مصطلحات موضوعية: Stereochemistry, medicine.medical_treatment, Avibactam, Microbial Sensitivity Tests, beta-Lactamases, Serine, 03 medical and health sciences, chemistry.chemical_compound, Mechanisms of Resistance, metallo-beta-lactamase, polycyclic compounds, medicine, Pharmacology (medical), IC50, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Vaborbactam, biology, 030306 microbiology, Chemistry, biochemical phenomena, metabolism, and nutrition, Editor's Pick, bacterial infections and mycoses, biology.organism_classification, Enterobacteriaceae, Anti-Bacterial Agents, Acinetobacter baumannii, Infectious Diseases, Enzyme, kinetics, QPX7728, Beta-lactamase, serine beta-lactamase, beta-Lactamase Inhibitors, beta-lactamase inhibition, Monobactams

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c5d82eab6c1748767a1f9f49835ad1
https://doi.org/10.1128/aac.00130-20

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