نتائج البحث - "R. F. Adams"

1

Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin

المساهمون: Lord, Simon R. [0000-0001-7946-5609], Harris, Adrian L. [0000-0003-1376-8409], Apollo - University of Cambridge Repository, Lord, Simon R [0000-0001-7946-5609], Harris, Adrian L [0000-0003-1376-8409]

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, CANCER GENOMICS, Transcriptome, Mice, Diabetes mellitus genetics, chemistry.chemical_compound, 0302 clinical medicine, AMP-Activated Protein Kinase Kinases, CANCER METABOLISM, BREAST CANCER, TARGET IDENTIFICATION, CANCER GENOMICS, BIOINFORMATICS, DATA SCIENCE, COMPUTATIONAL BIOLOGY, Beta oxidation, 0303 health sciences, 631/154/555, Fatty Acids, BIOINFORMATICS, article, Metformin, Mitochondria, 3. Good health, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Heterografts, Female, Oxidation-Reduction, COMPUTATIONAL BIOLOGY, medicine.drug, CANCER METABOLISM, DATA SCIENCE, Breast Neoplasms, 631/67/69, 631/67/2327, 03 medical and health sciences, BREAST CANCER, Diabetes Mellitus, medicine, Animals, Humans, Cell Proliferation, 030304 developmental biology, Triglyceride, business.industry, Gene Expression Profiling, AMPK, 631/67/1347, Gene signature, Lipid Metabolism, chemistry, Cancer cell, Cancer research, Lipid Peroxidation, business, Protein Kinases, TARGET IDENTIFICATION

وصف الملف: text/xml; application/pdf; application/octet-stream

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577b9948a54adccc595d579b5e1b9cd9
https://www.repository.cam.ac.uk/handle/1810/314930

2

Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment

المؤلفون: Sonia Li, Simon Lord, N P Hughes, Ruud G.P.M. van Stiphout, Andreas Makris, R F Adams, Adrian M. Jubb, Lefteris Koumakis, S Mehta, Francesca M. Buffa, Adrian L. Harris, Anwar R. Padhani

المصدر: EBioMedicine
EBioMedicine, Vol 10, Iss C, Pp 109-116 (2016)

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, 0301 basic medicine, Bevacizumab, DCE-MRI, Resistance, Radiogenomics, lcsh:Medicine, Angiogenesis Inhibitors, Antineoplastic Agents, Breast Neoplasms, Biology, General Biochemistry, Genetics and Molecular Biology, Immunomodulation, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, Immune system, Anti-angiogenic treatment, Downregulation and upregulation, Biomarkers, Tumor, medicine, Cluster Analysis, Humans, Cell Proliferation, lcsh:R5-920, Tumor microenvironment, Neovascularization, Pathologic, lcsh:R, Cancer, General Medicine, medicine.disease, Magnetic Resonance Imaging, Immune checkpoint, Gene Expression Regulation, Neoplastic, Treatment Outcome, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Immunology, Cancer research, Female, lcsh:Medicine (General), Energy Metabolism, Transcriptome, Signal Transduction, Research Paper, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ceaf12d0292dcef2007f8e74fe4ce07
https://doi.org/10.1016/j.ebiom.2016.07.017

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3

Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer

المساهمون: Frezza, Christian [0000-0002-3293-7397], Apollo - University of Cambridge Repository

المصدر: CELL METABOLISM
Cell Metabolism

مصطلحات موضوعية: 0301 basic medicine, A300 Clinical Medicine, positron emission tomography, endocrine system diseases, Physiology, B210 Pharmacology, cancer metabolism, Mitochondrion, Transcriptome, 0302 clinical medicine, Positron Emission Tomography Computed Tomography, G150 Mathematical Modelling, B100 Anatomy, Physiology and Pathology, C130 Cell Biology, Middle Aged, metabolomics, Metformin, 3. Good health, Mitochondria, B800 Medical Technology, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Female, Metabolic Networks and Pathways, medicine.drug, Adult, Antineoplastic Agents, Breast Neoplasms, 03 medical and health sciences, Metabolomics, Breast cancer, B132 Pathobiology, medicine, gene expression profiling, Humans, Hypoglycemic Agents, Molecular Biology, Aged, business.industry, Cell Biology, clinical study, medicine.disease, Gene expression profiling, Clinical trial, 030104 developmental biology, Glucose, Cancer research, C100 Biology, business, Flux (metabolism)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a168f8387e5f05dbe5abffbe69c6fc
https://www.repository.cam.ac.uk/handle/1810/285637

4

Abstract P1-06-01: Upregulation of metabolism as a potential resistance mechanism to bevacizumab in primary breast cancer

المؤلفون: Andreas Makris, N P Hughes, Anwar R. Padhani, Sonia P. Li, Francesca M. Buffa, Cheng Han, NJ Taylor, S Mehta, K Kaur, Al Harris, R F Adams

المصدر: Cancer Research. 72:P1-06

مصطلحات موضوعية: Oncology, Cancer Research, Chemotherapy, Pathology, medicine.medical_specialty, Bevacizumab, business.industry, medicine.medical_treatment, Cancer, medicine.disease, Metastatic breast cancer, Gene expression profiling, Breast cancer, Pharmacokinetics, Internal medicine, medicine, Progression-free survival, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::90b01fae581d781b3a02e74b4514a49d
https://doi.org/10.1158/0008-5472.sabcs12-p1-06-01

5

Assessing Early Therapeutic Response to Bevacizumab in Primary Breast Cancer Using Magnetic Resonance Imaging and Gene Expression Profiles

المؤلفون: Anwar R. Padhani, N C Levitt, S Mehta, N P Hughes, Sonia P. Li, Andreas Makris, R F Adams, A Adwani, Francesca M. Buffa, NJ Taylor, Adrian L. Harris

المصدر: JNCI Monographs

مصطلحات موضوعية: Gadolinium DTPA, Vascular Endothelial Growth Factor A, Oncology, Cancer Research, medicine.medical_specialty, Pathology, Bevacizumab, Contrast Media, Angiogenesis Inhibitors, Breast Neoplasms, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Predictive Value of Tests, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Gene expression, Biomarkers, Tumor, medicine, Medical imaging, Humans, 030304 developmental biology, 0303 health sciences, medicine.diagnostic_test, business.industry, Gene Expression Profiling, Biopsy, Needle, Cancer, Magnetic resonance imaging, General Medicine, medicine.disease, Magnetic Resonance Imaging, Neoadjuvant Therapy, 3. Good health, Gene Expression Regulation, Neoplastic, Gene expression profiling, Receptors, Vascular Endothelial Growth Factor, Treatment Outcome, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Female, Primary breast cancer, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047747ff69b47c1ea95fa2f377d6503f
https://doi.org/10.1093/jncimonographs/lgr027

6

Abstract P2-09-28: Integrated Gene Expression and MRI Analysis To Assess Early Therapeutic Response to Bevacizumab in Primary Breast Cancer

المؤلفون: Sonia P. Li, Anwar R. Padhani, R F Adams, NJ Taylor, Francesca M. Buffa, S Mehta, Andreas Makris, N P Hughes, A Adwani, A L Harris, N C Levitt

المصدر: Cancer Research. 70:P2-09

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c472b29cd84cd2b574ce47fc74d472c4
https://doi.org/10.1158/0008-5472.sabcs10-p2-09-28

7

Percutaneous Image-Guided Cutting Needle Biopsy of the Pleura in the Diagnosis of Malignant Mesothelioma

المؤلفون: R F Adams, Winifred Gray, Robert J. O. Davies, Fergus V. Gleeson

المصدر: Chest. 120:1798-1802

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e872341834005fff29b83acec2bfc4b
https://doi.org/10.1378/chest.120.6.1798

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8

Screwdriver Headache: A Case of Traumatic Intracranial Hypotension

المؤلفون: Kevin Talbot, R F Adams, Philip Anslow

المصدر: Clinical Radiology. 56:676-680

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7c85fb437e3a28cafc5218ef5eeac6
https://doi.org/10.1053/crad.1999.0461

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9

The natural history of transdural herniation of the spinal cord: case report

المؤلفون: P. Anslow, R. F. Adams

المصدر: Neuroradiology. 43:383-387

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2c226ed0a736be57eba4fc4553aa86
https://doi.org/10.1007/s002340000469

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10

X-ray imaging techniques onZusing the Z-Beamlet laser

المؤلفون: John L. Porter, Otto Landen, Guy R. Bennett, L. E. Ruggles, R. F. Adams, C. Wakefield, Walter W. Simpson

المصدر: Review of Scientific Instruments. 72:657-662

مصطلحات موضوعية: Physics, Opacity, business.industry, Plasma, Laser, law.invention, Optics, Industrial radiography, law, Z-pinch, Plasma diagnostics, business, Instrumentation, Inertial confinement fusion, Image resolution

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d4f91f1ce0b995b03f30075a17188b49
https://doi.org/10.1063/1.1315645

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