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1
المؤلفون: R. F. Bousley, Karen L Rogers, Kim P. Gallagher, Paul L. Juneau, Nancy Janiczek, Thomas E. Mertz, Liguo Chi, Yun-Wen Peng, Lori J. Saganek, Andrew C.G. Uprichard
المصدر: Journal of Thrombosis and Thrombolysis. 11:19-31
مصطلحات موضوعية: medicine.diagnostic_test, business.industry, medicine.drug_class, Anticoagulant, Hematology, Pharmacology, medicine.disease, chemistry.chemical_compound, Bolus (medicine), chemistry, Direct thrombin inhibitor, Bleeding time, Anesthesia, Antithrombotic, Medicine, Inogatran, Thrombus, Cardiology and Cardiovascular Medicine, business, Discovery and development of direct thrombin inhibitors
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2
المؤلفون: Diane P. Ignasiak, Kim P. Gallagher, Thomas E. Mertz, In-Chull Kim, Thomas B. McClanahan, Paul L. Juneau, R. F. Bousley, Nancy Janiczek-Dolphin, Gary Hicks
المصدر: Journal of Thrombosis and Thrombolysis. 10:277-284
مصطلحات موضوعية: medicine.diagnostic_test, business.industry, Vascular disease, Activated clotting time, Hematology, Thrombin time, medicine.disease, Thrombosis, medicine.anatomical_structure, Oral administration, Direct thrombin inhibitor, Anesthesia, medicine, Cardiology and Cardiovascular Medicine, business, Vein, Partial thromboplastin time
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3
المؤلفون: Helen T. Lee, Brian R. Krause, Bruce D. Roth, R. L. Stanfield, W. H. Roark, Joseph Armand Picard, Drago Robert Sliskovic, R. F. Bousley, K. L. Hamelehle
المصدر: Bioorganic & Medicinal Chemistry Letters. 8:289-294
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Clinical Biochemistry, Sterol O-acyltransferase, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Organophosphorus Compounds, Microsomes, Drug Discovery, medicine, Animals, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Sulfonamides, biology, Cholesterol, Anticholesteremic Agents, Organic Chemistry, Phosphoramidate, Enzyme, chemistry, Acyltransferases, Enzyme inhibitor, biology.protein, Molecular Medicine, Rabbits, Sterol O-Acyltransferase
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4
المؤلفون: Brian K Krause, Mark A. Spahr, Randy Ramharack, Helen T. Lee, R. F. Bousley, Catherine S. Sekerke, R. L. Stanfield
المصدر: Atherosclerosis. 136:79-87
مصطلحات موضوعية: Male, medicine.medical_specialty, Apolipoprotein B, Acetates, Apoprotein(a), chemistry.chemical_compound, In vivo, Internal medicine, Acetamides, Blood plasma, medicine, Animals, Enzyme Inhibitors, Cells, Cultured, Apolipoproteins B, Sulfonamides, Apolipoprotein A-I, biology, Cholesterol, Anticholesteremic Agents, Lipoprotein(a), Animal Feed, Macaca fascicularis, Apolipoproteins, medicine.anatomical_structure, Endocrinology, Liver, chemistry, Hepatocyte, Low-density lipoprotein, Apolipoprotein B-100, biology.protein, lipids (amino acids, peptides, and proteins), Sulfonic Acids, Cardiology and Cardiovascular Medicine, Sterol O-Acyltransferase, Lipoprotein
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5
المؤلفون: Maureen K. Anderson, Andrew D. White, Thomas M.A. Bocan, R. F. Bousley, Claude Forsey Purchase, Sandra Bak Mueller, Brian R. Krause, Peter Lee, J. F. Reindel, Reynold Homan, R. L. Stanfield, K. L. Hamelehle, Cecilia Speyer
المصدر: Bioorganic & Medicinal Chemistry Letters. 6:1753-1758
مصطلحات موضوعية: Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Acyl CoA cholesterol O acyltransferase, Biochemistry, In vitro, chemistry.chemical_compound, Nucleophile, In vivo, Drug Discovery, Urea, Molecular Medicine, Tetrazole, Molecular Biology, Serum cholesterol
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6
المؤلفون: Maureen K. Anderson, Patrice Lee, J. F. Reindel, K. L. Hamelehle, R. L. Stanfield, Drago Sliskovic, J. A. Picard, Bruce D. Roth, B.R. Krause, D. Turluck, Andrew D. White, Sandra Bak Mueller, Reynold Homan, Thomas M.A. Bocan, Patrick Michael O'brien, Helen Tsenwhei Lee, Claude Forsey Purchase, R. F. Bousley
المصدر: Journal of Medicinal Chemistry. 39:2354-2366
مصطلحات موضوعية: Male, Arteriosclerosis, Stereochemistry, Guinea Pigs, Hypercholesterolemia, Drug Evaluation, Preclinical, Tetrazoles, Cholesterol, Dietary, Structure-Activity Relationship, chemistry.chemical_compound, Amide, Drug Discovery, Animals, Moiety, Tetrazole, Enzyme Inhibitors, Fatty acid amide, Molecular Structure, Cholesterol, Anticholesteremic Agents, Macrophages, Biological activity, Rats, chemistry, Drug Design, Microsomes, Liver, Microsome, Molecular Medicine, Rabbits, Acetamide, Sterol O-Acyltransferase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50d87ec1d2a4e896eabf54421ba52bd
https://doi.org/10.1021/jm960170f -
7
المؤلفون: Maureen K. Anderson, Reynold Homan, Joseph Armand Picard, R. L. Stanfield, Bruce D. Roth, Brian R. Krause, K. L. Hamelehle, W. Howard Roark, R. F. Bousley
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:2367-2370
مصطلحات موضوعية: chemistry.chemical_classification, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Sterol O-acyltransferase, Pharmaceutical Science, Biochemistry, Sulfonylurea, In vitro, Enzyme, Plasma cholesterol, chemistry, In vivo, Drug Discovery, medicine, Molecular Medicine, lipids (amino acids, peptides, and proteins), Molecular Biology
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8
المؤلفون: Timothy R. Hurley, R. L. Stanfield, Maureen K. Anderson, Brian R. Krause, Drago Robert Sliskovic, Adele Bernabei, Patrick Michael O'brien, R. F. Bousley
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:295-300
مصطلحات موضوعية: Stereochemistry, Cholesterol, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Acyl transferase, In vitro, chemistry.chemical_compound, Acyl-CoA, Acetic acid, Design synthesis, chemistry, In vivo, Drug Discovery, Molecular Medicine, Tetrazole, Molecular Biology
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9
المؤلفون: R. F. Bousley, Brian R. Krause, Helen T. Lee, K. L. Hamelehle, Drago Robert Sliskovic, R. L. Stanfield
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:301-306
مصطلحات موضوعية: chemistry.chemical_classification, Very low-density lipoprotein, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Acyl CoA cholesterol O acyltransferase, Biochemistry, Sulfonamide, chemistry.chemical_compound, Drug Discovery, Molecular Medicine, lipids (amino acids, peptides, and proteins), Secretion, Tetrazole, Molecular Biology, Dietary Cholesterol
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10
المؤلفون: Brian R. Krause, Maureen K. Anderson, R. L. Stanfield, R. F. Bousley, Drago Robert Sliskovic, Patrick Michael O'brien
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:289-294
مصطلحات موضوعية: chemistry.chemical_classification, Nicotinamide, Cholesterol, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Fatty acid, Biological activity, Biochemistry, In vitro, chemistry.chemical_compound, Acyl-CoA, chemistry, Drug Discovery, Molecular Medicine, Tetrazole, Benzamide, Molecular Biology