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1
المؤلفون: Helen T. Lee, Brian R. Krause, Bruce D. Roth, R. L. Stanfield, W. H. Roark, Joseph Armand Picard, Drago Robert Sliskovic, R. F. Bousley, K. L. Hamelehle
المصدر: Bioorganic & Medicinal Chemistry Letters. 8:289-294
مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Clinical Biochemistry, Sterol O-acyltransferase, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Organophosphorus Compounds, Microsomes, Drug Discovery, medicine, Animals, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Sulfonamides, biology, Cholesterol, Anticholesteremic Agents, Organic Chemistry, Phosphoramidate, Enzyme, chemistry, Acyltransferases, Enzyme inhibitor, biology.protein, Molecular Medicine, Rabbits, Sterol O-Acyltransferase
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2
المؤلفون: Brian K Krause, Mark A. Spahr, Randy Ramharack, Helen T. Lee, R. F. Bousley, Catherine S. Sekerke, R. L. Stanfield
المصدر: Atherosclerosis. 136:79-87
مصطلحات موضوعية: Male, medicine.medical_specialty, Apolipoprotein B, Acetates, Apoprotein(a), chemistry.chemical_compound, In vivo, Internal medicine, Acetamides, Blood plasma, medicine, Animals, Enzyme Inhibitors, Cells, Cultured, Apolipoproteins B, Sulfonamides, Apolipoprotein A-I, biology, Cholesterol, Anticholesteremic Agents, Lipoprotein(a), Animal Feed, Macaca fascicularis, Apolipoproteins, medicine.anatomical_structure, Endocrinology, Liver, chemistry, Hepatocyte, Low-density lipoprotein, Apolipoprotein B-100, biology.protein, lipids (amino acids, peptides, and proteins), Sulfonic Acids, Cardiology and Cardiovascular Medicine, Sterol O-Acyltransferase, Lipoprotein
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3
المؤلفون: R. L. Stanfield, K. L. Hamelehle, Brian R. Krause, Bharat K. Trivedi, A. D. Essenburg, Ann Holmes, Terri S. Purchase, MaryKay Shaw Hes
المصدر: Bioorganic & Medicinal Chemistry. 5:739-747
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Stereochemistry, Hypercholesterolemia, Clinical Biochemistry, Rat model, Sterol O-acyltransferase, Administration, Oral, Pharmaceutical Science, Biochemistry, Fluorides, Structure-Activity Relationship, chemistry.chemical_compound, Total cholesterol, Drug Discovery, Benzene Derivatives, Animals, Urea, Structure–activity relationship, Molecular Biology, Total plasma, Chemistry, Cholesterol, Anticholesteremic Agents, Organic Chemistry, Diet, Rats, Cholesterol blood, Disease Models, Animal, Molecular Medicine, Rabbits, Sterol O-Acyltransferase
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4
المؤلفون: Maureen K. Anderson, Andrew D. White, Thomas M.A. Bocan, R. F. Bousley, Claude Forsey Purchase, Sandra Bak Mueller, Brian R. Krause, Peter Lee, J. F. Reindel, Reynold Homan, R. L. Stanfield, K. L. Hamelehle, Cecilia Speyer
المصدر: Bioorganic & Medicinal Chemistry Letters. 6:1753-1758
مصطلحات موضوعية: Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Acyl CoA cholesterol O acyltransferase, Biochemistry, In vitro, chemistry.chemical_compound, Nucleophile, In vivo, Drug Discovery, Urea, Molecular Medicine, Tetrazole, Molecular Biology, Serum cholesterol
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5
المؤلفون: Drago Sliskovic, Essenburg Ad, Joseph Armand Picard, J. F. Reindel, L. L. Minton, B.R. Krause, R. L. Stanfield, W. H. Roark
المصدر: Bioorganic & Medicinal Chemistry Letters. 6:713-718
مصطلحات موضوعية: chemistry.chemical_classification, Cholesterol, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biological activity, Pharmacology, Biochemistry, Acyl transferase, chemistry.chemical_compound, Acyl-CoA, Enzyme, chemistry, Amide, Drug Discovery, Molecular Medicine, Bioassay, Molecular Biology, Ex vivo
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6
المؤلفون: Maureen K. Anderson, Patrice Lee, J. F. Reindel, K. L. Hamelehle, R. L. Stanfield, Drago Sliskovic, J. A. Picard, Bruce D. Roth, B.R. Krause, D. Turluck, Andrew D. White, Sandra Bak Mueller, Reynold Homan, Thomas M.A. Bocan, Patrick Michael O'brien, Helen Tsenwhei Lee, Claude Forsey Purchase, R. F. Bousley
المصدر: Journal of Medicinal Chemistry. 39:2354-2366
مصطلحات موضوعية: Male, Arteriosclerosis, Stereochemistry, Guinea Pigs, Hypercholesterolemia, Drug Evaluation, Preclinical, Tetrazoles, Cholesterol, Dietary, Structure-Activity Relationship, chemistry.chemical_compound, Amide, Drug Discovery, Animals, Moiety, Tetrazole, Enzyme Inhibitors, Fatty acid amide, Molecular Structure, Cholesterol, Anticholesteremic Agents, Macrophages, Biological activity, Rats, chemistry, Drug Design, Microsomes, Liver, Microsome, Molecular Medicine, Rabbits, Acetamide, Sterol O-Acyltransferase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50d87ec1d2a4e896eabf54421ba52bd
https://doi.org/10.1021/jm960170f -
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المؤلفون: Maureen K. Anderson, Reynold Homan, Joseph Armand Picard, R. L. Stanfield, Bruce D. Roth, Brian R. Krause, K. L. Hamelehle, W. Howard Roark, R. F. Bousley
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:2367-2370
مصطلحات موضوعية: chemistry.chemical_classification, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Sterol O-acyltransferase, Pharmaceutical Science, Biochemistry, Sulfonylurea, In vitro, Enzyme, Plasma cholesterol, chemistry, In vivo, Drug Discovery, medicine, Molecular Medicine, lipids (amino acids, peptides, and proteins), Molecular Biology
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8
المؤلفون: R. L. Stanfield, Bharat K. Trivedi, Brian R. Krause, A. D. Essenburg, K. L. Hamelehle, Terri S. Purchase, Ann Holmes, MaryKay Shaw Hes
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:2229-2234
مصطلحات موضوعية: Steric effects, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, In vitro, Plasma cholesterol, In vivo, Drug Discovery, Molecular Medicine, lipids (amino acids, peptides, and proteins), Molecular Biology
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9
المؤلفون: Timothy R. Hurley, R. L. Stanfield, Maureen K. Anderson, Brian R. Krause, Drago Robert Sliskovic, Adele Bernabei, Patrick Michael O'brien, R. F. Bousley
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:295-300
مصطلحات موضوعية: Stereochemistry, Cholesterol, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Acyl transferase, In vitro, chemistry.chemical_compound, Acyl-CoA, Acetic acid, Design synthesis, chemistry, In vivo, Drug Discovery, Molecular Medicine, Tetrazole, Molecular Biology
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10
المؤلفون: R. F. Bousley, Brian R. Krause, Helen T. Lee, K. L. Hamelehle, Drago Robert Sliskovic, R. L. Stanfield
المصدر: Bioorganic & Medicinal Chemistry Letters. 5:301-306
مصطلحات موضوعية: chemistry.chemical_classification, Very low-density lipoprotein, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Acyl CoA cholesterol O acyltransferase, Biochemistry, Sulfonamide, chemistry.chemical_compound, Drug Discovery, Molecular Medicine, lipids (amino acids, peptides, and proteins), Secretion, Tetrazole, Molecular Biology, Dietary Cholesterol