المؤلفون: Mengge Du, Yujiao Chen, Yan Chang, Wei Liu, Ping Xie, Fan Liu, Shuai Tong

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: KI, knock-in, Carcinogenesis, RBX1, RRP9, UBE2F, ubiquitin conjugating enzyme E2 F, C-CBL, casitas B-lineage lymphoma c, Biochemistry, NEDD8, Mice, neddylation, Ubiquitin, Ribonucleoproteins, Small Nucleolar, chemistry.chemical_classification, Mice, Inbred BALB C, biology, UBE2M, ubiquitin conjugating enzyme E2 M, Ubiquitin ligase, Cell biology, Neoplasm Proteins, PTEN, gene of phosphate and tension homology deleted on chromsome ten, XIAP, X-linked inhibitor of apoptosis, Mdm2, SIRT7, sirtuin 7, NEDP1, nedd8 protease 1, RNF168, ring finger protein 168, HT29 Cells, Research Article, NEDD8 Protein, Ubiquitin-Protein Ligases, Mutation, Missense, Mice, Nude, MDM2, mouse double minute 2, NAE1, NEDD8 activating enzyme E1 subunit 1, RBX1, ring-box 1, Animals, Humans, Smurf1, MEKK2, mitogen-activated protein kinase kinase kinase 2, Molecular Biology, DNA ligase, KO, knockout, PCAF, P300/CBP-associated factor, UBA3, ubiquitin-like modifier activating enzyme 3, SnoRNA binding, CSN5, COP9 signalosome subunit 5, RNF111, ring finger protein 111, Cell Biology, HCT116 Cells, tumorigenesis, chemistry, Amino Acid Substitution, RRP9, ribosomal RNA processing 9, biology.protein, Neddylation, Protein Processing, Post-Translational, DCN1, defective in cullin neddylation protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43e1f808c822b0e7519b6d27b8c63ff
https://pubmed.ncbi.nlm.nih.gov/36270201

المؤلفون: Ferbian Milas Siswanto, Ami Oguro, Susumu Imaoka

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, DNA damage-binding protein 1, CUL4A, Cullin 4A, Cullin4A, RBX1, Ring-box 1, Biochemistry, Nrf2, nuclear factor erythroid 2-related factor 2, nuclear factor 2 (erythroid-derived 2-like factor), Ubiquitin, oxidative stress, Post-translational regulation, HO-1, heme oxygenase-1, biology, Chemistry, DDB1, DNA damage-binding protein 1, Sp1, specificity protein 1, Ubiquitin ligase, Cell biology, Keap1, Kelch-like ECH-associated protein 1, Kelch-Like ECH-Associated Protein 1, Ubiquitin ligase complex, shRNA, short hairpin RNA, Cullin, Research Article, NF-E2-Related Factor 2, Sp1 Transcription Factor, Ubiquitin-Protein Ligases, posttranslational regulation, ARE, antioxidant response elements, Kelch-like ECH-associated protein 1, CRL4, Cullin 4-RING ligase, 03 medical and health sciences, DDB1, WD40 repeat protein 23, Cell Line, Tumor, Cullin 4A-RING ligase, Humans, specificity protein 1, Molecular Biology, KD, knockdown, 030102 biochemistry & molecular biology, Cell Biology, Ring-box 1, Kinetics, 030104 developmental biology, Gene Expression Regulation, biology.protein, CUL4A, gene regulation, NQO1, NAD(P)H quinone dehydrogenase 1, WDR23, WD40 repeat protein 23

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707cf01346d6f8bd9189f7ef3b137d58
http://europepmc.org/articles/PMC8141886

المؤلفون: Thomas Macartney, Youcef Mehellou, Frances-Rose Schumacher, Axel Knebel, Akihito Ohta, Dario R. Alessi, Nicola T. Wood, Clare Johnson, Thimo Kurz

المصدر: Biochemical Journal

مصطلحات موضوعية: Small interfering RNA, Pseudohypoaldosteronism, SPS1-related proline/alanine-rich kinase/oxidative stress-responsive kinase 1 (SPAK/OSR1), DCT, distal convoluted tubule, KLHL3, Kelch-like 3, Biochemistry, OSR1, oxidative stress-responsive kinase 1, rTEV, recombinant tobacco etch virus, 0302 clinical medicine, UBE2D3, ubiquitin-conjugating enzyme E2 D3, WNK Lysine-Deficient Protein Kinase 1, Ubiquitin, GST, glutathione transferase, Solute Carrier Family 12, Member 2, Na+/Cl− co-transporter (NCC), BTB domain, Na+/K+/2Cl− co-transporter 2 (NKCC2), GFP, green fluorescent protein, 0303 health sciences, RT, reverse transcription, LC, liquid chromatography, Kinase, Microfilament Proteins, Intracellular Signaling Peptides and Proteins, HRP, horseradish peroxidase, Cullin Proteins, WNK1, WNK4, Ubiquitin ligase, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, KEAP1, Kelch-like ECH-associated protein 1, UBE1, ubiquitin-like modifier-activating enzyme 1, RM, Sodium-Potassium-Chloride Symporters, RBX1, RING-box 1, E3 ubiquitin protein ligase, Kelch-like domain (KLHL domain), SPAK, SPS1-related proline/alanine-rich kinase, Mutation, Missense, TTBS, Tris-buffered saline containing Tween 20, Accelerated Publication, Protein Serine-Threonine Kinases, Biology, Minor Histocompatibility Antigens, HEK, human embryonic kidney, 03 medical and health sciences, WNK, with no lysine kinase, ubiquitin, NCC, Na+/Cl− co-transporter, Humans, Kinase activity, CUL3, Cullin-3, CRL, Cullin–RING E3 ligase, Molecular Biology, qRT-PCR, real time quantitative reverse transcription PCR, Adaptor Proteins, Signal Transducing, 030304 developmental biology, urogenital system, Ubiquitination, Cullin–RING E3 ligase (CRL), Cell Biology, TAL, thick ascending limb, NRF2, NF-E2-related factor 2, RPL13A, ribosomal protein L13a, Molecular biology, HEK293 Cells, Amino Acid Substitution, DTT, dithiothreitol, siRNA, small interfering RNA, biology.protein, NKCC, Na+/K+/2Cl− co-transporter, Carrier Proteins, 030217 neurology & neurosurgery, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070788786abe18caa6db90ba6b935486
https://doi.org/10.1042/bj20121903

المؤلفون: Kostas Pantopoulos, Jian Wang

المصدر: Biochemical Journal

مصطلحات موضوعية: m-aconitase, mitochondrial aconitase, SLC, solute carrier, STAT3, signal transducer and activator of transcription 3, IRIDA, iron-refractory iron deficiency anaemia, Ferroportin, NTBI, non-transferrin-bound iron, Review Article, FLVCR, feline leukaemia virus, subgroup C, receptor, Biochemistry, transferrin receptor (TfR), IOP1, iron-only hydrogenase-like protein 1, Isu, iron–sulfur cluster scaffold homologue, TfR, Tf receptor, 0302 clinical medicine, DHBA, dihydroxybenzoic acid, Nar1, nuclear architecture-related protein 1, Nbp35, nucleotide-binding protein 35, Neoplasms, Metalloprotein, PCBP1, poly(rC)-binding protein 1, ferroportin, Nfs, nitrogen fixation homologue, chemistry.chemical_classification, 0303 health sciences, Abcb, ATP-binding cassette, subfamily B, Transferrin, Hpx, haemopexin, Iron-Regulatory Proteins, Biometal, Mitochondria, HIF, hypoxia-inducible factor, Rbx1, Ring-box 1, UTR, untranslated region, Grx, glutaredoxin, IRE, iron-responsive element, C/EBPα, CCAAT/enhancer-binding protein α, 030220 oncology & carcinogenesis, iron–sulfur cluster (ISC), SDH, succinate dehydrogenase, ISC, iron–sulfur cluster, FBXL5, F-box and leucine-rich repeat protein 5, Oxidation-Reduction, LIP, labile iron pool, c-aconitase, cytosolic aconitase, L, light, Iron, Transferrin receptor, Lcn2, lipocalin 2, HO-1, haem oxygenase 1, Biology, Endocytosis, Response Elements, Dcytb, duodenal cytochrome b, Cfd1, cytosolic Fe–S cluster-deficient protein 1, H, heavy, ER, endoplasmic reticulum, 03 medical and health sciences, DMT1, divalent metal transporter 1, β-APP, β-amyloid precursor protein, ROS, reactive oxygen species, iron-regulatory protein 1 (IRP1), Skp1, S-phase kinase-associated protein 1, Tf, transferrin, Animals, Humans, RNA, Messenger, Molecular Biology, 030304 developmental biology, ferritin, Cul1, Cullin 1, BMP, bone morphogenetic protein, Biological Transport, Cell Biology, MRCKα, myotonic dystrophy kinase-related Cdc42 (cell division cycle 42)-binding kinase α, ALAS, ALA synthase, CIA, cytosolic ISC assembly, Ferritin, iron-regulatory protein 2 (IRP2), Cytosol, chemistry, IRP, iron-regulatory protein, Ferritins, biology.protein, ALA, 5-aminolevulinic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa24e375048710c7f32509cbef225d5
http://europepmc.org/articles/PMC3048577