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1دورية أكاديمية
المؤلفون: Singh R; Department of Chemistry, Kurukshetra University, Kurukshetra, 136119, Haryana, India; School of Chemistry, Indian Institutes of Science Education and Research, Thiruvananthapuram, Kerala, 695551, India., Sindhu J; Department of Chemistry, COBS&H, CCS Haryana Agricultural University, Hisar, 125004, India., Devi M; Department of Chemistry, Kurukshetra University, Kurukshetra, 136119, Haryana, India., Kumar P; Department of Chemistry, Kurukshetra University, Kurukshetra, 136119, Haryana, India. Electronic address: parvinchem@kuk.ac.in., Lal S; Department of Chemistry, Kurukshetra University, Kurukshetra, 136119, Haryana, India., Kumar A; Department of Pharmaceutical Sciences, GJUS&T, Hisar, -125001, India., Singh D; Department of Chemistry, Maharshi Dayanand University, Rohtak, India, 124001., Kumar H; Department of Chemistry, School of Basic Sciences, Central University Haryana, Mahendergarh, India.
المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Sep 05; Vol. 275, pp. 116623. Date of Electronic Publication: 2024 Jun 25.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Triazoles*/chemistry , Triazoles*/pharmacology , Triazoles*/chemical synthesis , Molecular Docking Simulation* , alpha-Amylases*/antagonists & inhibitors , alpha-Amylases*/metabolism , Molecular Dynamics Simulation* , Quantitative Structure-Activity Relationship* , Thiazolidinediones*/chemistry , Thiazolidinediones*/chemical synthesis , Thiazolidinediones*/pharmacology, Molecular Structure ; Dose-Response Relationship, Drug ; Humans
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2دورية أكاديمية
المؤلفون: Xu T; Department of Medicinal Chemistry, School of Pharmacy, Chongqing Medical University, Chongqing, 400016, PR China., Yang J; Department of Medicinal Chemistry, School of Pharmacy, Chongqing Medical University, Chongqing, 400016, PR China., Li D; Department of Medicinal Chemistry, School of Pharmacy, Chongqing Medical University, Chongqing, 400016, PR China., Challa M; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China., Zou C; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China., Deng P; Department of Medicinal Chemistry, School of Pharmacy, Chongqing Medical University, Chongqing, 400016, PR China. Electronic address: 100865@cqmu.ed.cn., Zhang SL; School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing, 401331, PR China. Electronic address: zhangsl@cqu.edu.cn., Xu B; Department of Medicinal Chemistry, School of Pharmacy, Chongqing Medical University, Chongqing, 400016, PR China. Electronic address: xubiao@cqmu.edu.cn.
المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Sep 05; Vol. 275, pp. 116610. Date of Electronic Publication: 2024 Jun 17.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Isocitrate Dehydrogenase*/antagonists & inhibitors , Isocitrate Dehydrogenase*/genetics , Isocitrate Dehydrogenase*/metabolism , Biological Products*/pharmacology , Biological Products*/chemistry , Biological Products*/chemical synthesis , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/chemical synthesis , Cell Proliferation*/drug effects , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Drug Discovery* , Drug Screening Assays, Antitumor* , Dose-Response Relationship, Drug*, Humans ; Structure-Activity Relationship ; Animals ; Mice ; Molecular Structure ; Mutation ; Cell Line, Tumor ; Drug Evaluation, Preclinical ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/pathology ; Neoplasms, Experimental/metabolism
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3دورية أكاديمية
المؤلفون: Abd El-Mawgoud HK; Chemistry Department, Faculty of Women for Arts, Science and Education, Ain Shams University, Heliopolis, 11767 Cairo, Egypt. Electronic address: Heba.Kamal@women.asu.edu.eg., AboulMagd AM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Nahda University (NUB), Beni-Suef, Egypt. Electronic address: asmaa.aboulmaged@nub.edu.eg., Nemr MTM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Eini Street 11562, Cairo, Egypt., Hemdan MM; Chemistry Department, Faculty of Science, Ain Shams University, Abbasia, 11566 Cairo, Egypt., Hassaballah AI; Chemistry Department, Faculty of Science, Ain Shams University, Abbasia, 11566 Cairo, Egypt., Farag PS; Chemistry Department, Faculty of Science, Ain Shams University, Abbasia, 11566 Cairo, Egypt.
المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107622. Date of Electronic Publication: 2024 Jul 09.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors , Vascular Endothelial Growth Factor Receptor-2*/metabolism , Pyrimidines*/pharmacology , Pyrimidines*/chemical synthesis , Pyrimidines*/chemistry , Apoptosis*/drug effects , Drug Design* , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Autophagy*/drug effects , Drug Screening Assays, Antitumor* , Cell Proliferation*/drug effects , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Protein Kinase Inhibitors*/chemistry , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/antagonists & inhibitors , Dose-Response Relationship, Drug*, Humans ; Structure-Activity Relationship ; Molecular Structure ; Molecular Docking Simulation ; Cell Line, Tumor
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4دورية أكاديمية
المؤلفون: Qi S; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Guo L; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Liang J; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Wang K; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Liao Q; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China; Shandong Kangqiao Biotechnology Co., Ltd, Qingdao 266033, Shandong, People's Republic of China., He S; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang 550004, China., Lyu W; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, People's Republic of China., Cheng Z; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Wang J; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Luo X; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Yan X; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Lu Z; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Wang X; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China., Wang Z; School of Pharmacy, Binzhou Medical University, Yantai 256699, Shandong, People's Republic of China., Chen X; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China. Electronic address: chenxuehong@qdu.edu.cn., Li Q; Department of Medical Pharmacy, School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, People's Republic of China. Electronic address: 511867569@qq.com.
المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107612. Date of Electronic Publication: 2024 Jul 02.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Monophenol Monooxygenase*/antagonists & inhibitors , Monophenol Monooxygenase*/metabolism , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemical synthesis , Parkinson Disease*/drug therapy , Parkinson Disease*/metabolism , Dose-Response Relationship, Drug* , Drug Discovery*, Animals ; Structure-Activity Relationship ; Mice ; Molecular Structure ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/chemical synthesis ; Humans ; Male ; Molecular Docking Simulation ; Blood-Brain Barrier/metabolism
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5دورية أكاديمية
المؤلفون: Benoune RA; Laboratory of Synthesis of Molecules with Biological Interest, Faculty of Exact Sciences, Mentouri - Constantine 1 University, 25000 Constantine, Algeria., Dems MA; Biotechnology Research Center,25000 Constantine, Algeria., Boulcina R; Laboratory of Synthesis of Molecules with Biological Interest, Faculty of Exact Sciences, Mentouri - Constantine 1 University, 25000 Constantine, Algeria; Department of Engineering Process, Faculty of Technology, Mostefa Benboulaïd-Batna 2 University, 5000 Batna, Algeria. Electronic address: r.boulcina@univ-batna2.dz., Bensouici C; Biotechnology Research Center,25000 Constantine, Algeria., Robert A; Reims Champagne-Ardenne University, CNRS UMR 7312, ICMR, URCATech, 51100 Reims, France., Harakat D; Reims Champagne-Ardenne University, CNRS UMR 7312, ICMR, URCATech, 51100 Reims, France., Debache A; Laboratory of Synthesis of Molecules with Biological Interest, Faculty of Exact Sciences, Mentouri - Constantine 1 University, 25000 Constantine, Algeria.
المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107598. Date of Electronic Publication: 2024 Jun 28.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Butyrylcholinesterase*/metabolism , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemical synthesis , Cholinesterase Inhibitors*/chemistry , Quantitative Structure-Activity Relationship* , Antioxidants*/pharmacology , Antioxidants*/chemical synthesis , Antioxidants*/chemistry , Molecular Docking Simulation*, Molecular Structure ; Humans ; Dose-Response Relationship, Drug ; Acetylcholinesterase/metabolism
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6دورية أكاديمية
المؤلفون: Zhang Y; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China., Kang J; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China., Zhou Q; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China., Chen M; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China., Zhang J; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China., Shi Z; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China., Qiao Y; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, 430062, People's Republic of China., Qi C; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China; Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan 430030, People's Republic of China. Electronic address: qichangxing@hust.edu.cn., Zhang Y; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China. Electronic address: zhangyh@mails.tjmu.edu.cn.
المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107575. Date of Electronic Publication: 2024 Jun 17.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Penicillium*/chemistry , Lipopolysaccharides*/pharmacology , Lipopolysaccharides*/antagonists & inhibitors , Dose-Response Relationship, Drug*, Mice ; Animals ; Molecular Structure ; Structure-Activity Relationship ; Microglia/drug effects ; Microglia/metabolism ; Nitric Oxide/antagonists & inhibitors ; Nitric Oxide/biosynthesis ; Nitric Oxide/metabolism ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/isolation & purification ; Drug Discovery ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/isolation & purification
SCR Organism: Penicillium citrinum
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7دورية أكاديمية
المؤلفون: Liang Q; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China., Zhang S; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China., Liu J; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, China., Zhou X; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China; Department of Pharmacology and Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor., Syamimi Ariffin N; Department of Pharmacology and Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor., Wei J; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China., Shi C; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China., Ma X; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China. Electronic address: mxl78@glmc.edu.cn., Zhang Y; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China. Electronic address: zhangye81@126.com., Huang R; Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China. Electronic address: rzhuang1783@163.com.
المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107596. Date of Electronic Publication: 2024 Jun 26.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Carbonic Anhydrase IX*/antagonists & inhibitors , Carbonic Anhydrase IX*/metabolism , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/metabolism , Carbonic Anhydrase Inhibitors*/pharmacology , Carbonic Anhydrase Inhibitors*/chemistry , Carbonic Anhydrase Inhibitors*/chemical synthesis , Ferroptosis*/drug effects , Sulfonamides*/pharmacology , Sulfonamides*/chemistry , Sulfonamides*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Benzenesulfonamides* , Drug Screening Assays, Antitumor* , Cell Proliferation*/drug effects , Dose-Response Relationship, Drug* , Naphthalimides*/chemistry , Naphthalimides*/pharmacology , Naphthalimides*/chemical synthesis, Humans ; Animals ; Molecular Structure ; Structure-Activity Relationship ; Mice ; Female ; Drug Discovery ; Apoptosis/drug effects ; Molecular Docking Simulation ; Piperazines/pharmacology ; Piperazines/chemistry ; Piperazines/chemical synthesis ; Cell Line, Tumor ; Antigens, Neoplasm
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8دورية أكاديمية
المؤلفون: Hu Y; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China., Zhang Y; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China., Guo J; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China., Chen S; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China., Jin J; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China., Li P; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China., Pan Y; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China., Lei S; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China., Li J; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China., Wu S; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China., Bu B; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China., Fu L; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China; Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, China. Electronic address: lei.fu@xjtlu.edu.cn.
المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107588. Date of Electronic Publication: 2024 Jun 23.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Cell Proliferation*/drug effects , Mitochondria*/drug effects , Mitochondria*/metabolism , Drug Screening Assays, Antitumor* , Thiazoles*/pharmacology , Thiazoles*/chemistry , Thiazoles*/chemical synthesis , Membrane Potential, Mitochondrial*/drug effects , Apoptosis*/drug effects , Dose-Response Relationship, Drug* , Reactive Oxygen Species*/metabolism, Humans ; Structure-Activity Relationship ; Molecular Structure ; Cell Line, Tumor ; Organophosphorus Compounds/pharmacology ; Organophosphorus Compounds/chemistry ; Organophosphorus Compounds/chemical synthesis
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9دورية أكاديمية
المؤلفون: Wang Y; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Shen Z; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Chen R; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China., Chi X; Affiliated Yongkang First People's Hospital and School of Pharmacy, Hangzhou Medical College, Hangzhou 310014, Zhejiang, China., Li W; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China., Xu D; Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Lu Y; Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Ding J; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China., Dong X; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address: dongxw@zju.edu.cn., Zheng X; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou 310015, China. Electronic address: zhengxl@hzcu.edu.cn.
المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107553. Date of Electronic Publication: 2024 Jun 10.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Receptor, Fibroblast Growth Factor, Type 1*/antagonists & inhibitors , Receptor, Fibroblast Growth Factor, Type 1*/metabolism , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/metabolism , Molecular Dynamics Simulation* , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Drug Screening Assays, Antitumor* , Dose-Response Relationship, Drug* , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Cell Proliferation*/drug effects, Humans ; Structure-Activity Relationship ; Molecular Structure ; Drug Discovery ; Cell Movement/drug effects ; Molecular Docking Simulation ; Cell Line, Tumor ; Drug Evaluation, Preclinical
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10دورية أكاديمية
المؤلفون: Dong Z; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Pu Q; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Qiu Y; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Zhang R; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Chen Q; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Liu Q; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Khalid A; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Meng F; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Wang G; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China., Liao Z; Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, School of Life Sciences, Southwest University, Chongqing 400715, PR China., Chen M; Chongqing Key Laboratory of New Drug Screening from Traditional Chinese Medicine, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City & Southwest University, SWU-TAAHC Medicinal Plant Joint R&D Centre, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, PR China. Electronic address: mminchen@swu.edu.cn.
المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107564. Date of Electronic Publication: 2024 Jun 14.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
مواضيع طبية MeSH: Alkaloids*/chemistry , Alkaloids*/pharmacology , Alkaloids*/isolation & purification , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/chemistry , Antineoplastic Agents, Phytogenic*/isolation & purification , Dose-Response Relationship, Drug* , Drug Screening Assays, Antitumor* , Hypericum*/chemistry , Sesquiterpenes*/chemistry , Sesquiterpenes*/pharmacology , Sesquiterpenes*/isolation & purification, Humans ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cycloaddition Reaction ; Molecular Structure ; Stereoisomerism ; Structure-Activity Relationship ; Quinolines/chemistry ; Quinolines/isolation & purification ; Quinolines/pharmacology