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المؤلفون: Timothy G. Dinan, Conall R. Strain, Catherine Stanton, Fiona Fouhy, Gerard Clarke, Anna V. Golubeva, Sofia Cussotto, Alexander V. Zhdanov, Jacinta Walsh, John F. Cryan, Brendan T. Griffin, Niall P. Hyland
المصدر: EBioMedicine, Vol 66, Iss, Pp 103307-(2021)
EBioMedicineمصطلحات موضوعية: Male, 0301 basic medicine, Olanzapine, Medicine (General), Research paper, Bioavailability, medicine.medical_treatment, I.S., internal standard, HPLC, High performance liquid chromatography, Administration, Oral, MRT, mean residual time, Gut flora, Pharmacology, 5-HT, Serotonin (5-hydroxytryptamine), law.invention, MDR-1, multi-drug resistance protein 1, Antipsychotic, Feces, Probiotic, 0302 clinical medicine, Oral administration, law, CYP, RT-qPCR, reverse-transcriptase quantitative polymerase chain reaction, AUMC0-8h, area under the first-moment curve from time 0→ 8 hours after drug administered, Chromatography, High Pressure Liquid, Diversity, Molecular Structure, biology, CYP, Cytochrome p450 superfamily of enzymes, Biodiversity, General Medicine, LLE, liquid-liquid extraction, Anti-Bacterial Agents, RISP, risperidone, 030220 oncology & carcinogenesis, Medicine, Drug Monitoring, Selective Serotonin Reuptake Inhibitors, medicine.drug, % CV, Percentage coefficient of variation, Biological Availability, 5-HT-GLU, Serotonin β-D-Glucuronide, digestive system, General Biochemistry, Genetics and Molecular Biology, Cmax, maximum plasma concentration, 03 medical and health sciences, R5-920, Pharmacokinetics, OLZ, olanzapine, BCS, biopharmaceutical classification system, medicine, Animals, Microbiome, AUC0-8h, area under the plasma concentration vs time curve from time 0→ 8 hours after drug administered, business.industry, Probiotics, biology.organism_classification, Gastrointestinal Microbiome, Rats, GF, germ-free, 030104 developmental biology, UGT, Uridine 5′-diphospho-glucuronosyltransferase, business, Tmax, time taken to reach maximum plasma concentration
وصف الملف: application/pdf