المؤلفون: Jd, Atkin, Richard Pleass, Rj, Owens, Jm, Woof

المصدر: Europe PubMed Central

مصطلحات موضوعية: Mice, Biopolymers, Base Sequence, Protein Conformation, Genetic Vectors, Molecular Sequence Data, Mutagenesis, Site-Directed, Tumor Cells, Cultured, Animals, Humans, Protein Engineering, Recombinant Proteins, Immunoglobulin A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cf79789db5c45979b2e9f3db7fe0b940
https://pubmed.ncbi.nlm.nih.gov/8683109

المؤلفون: DJ King, P Antoniw, RJ Owens, JR Adair, AMR Haines, APH Farnsworth, H Finney, ADG Lawson, A Lyons, TS Baker, D Baldock, J Mackintosh, C Gofton, GT Yarranton, W McWilliams, D Shochat, PK Leichner, S Welt, LJ Old, A Mountain

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, DNA, Complementary, Immunoconjugates, medicine.drug_class, medicine.medical_treatment, Molecular Sequence Data, Transplantation, Heterologous, Gene Expression, Mice, Nude, CHO Cells, Monoclonal antibody, Immunoglobulin G, chemistry.chemical_compound, Mice, Antigen, Cricetinae, medicine, Tumor Cells, Cultured, DOTA, Animals, Humans, Avidity, Tissue Distribution, Yttrium Radioisotopes, Amino Acid Sequence, Cloning, Molecular, Immunoglobulin Fragments, Hybridomas, biology, Genes, Immunoglobulin, Indium Radioisotopes, Molecular biology, Immunoconjugate, Transplantation, Oncology, chemistry, Radioimmunotherapy, Immunology, biology.protein, Drug Screening Assays, Antitumor, Colorectal Neoplasms, Multiple Myeloma, Neoplasm Transplantation, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff814f55777341f412a91c8568934a0
http://ora.ox.ac.uk/objects/uuid:7021430e-1ee7-44ea-bd89-23a20d7b4b27

المؤلفون: Rj, Owens, Alberto Kornblihtt, Fe, Baralle

المصدر: Europe PubMed Central

مصطلحات موضوعية: Peptide Biosynthesis, Binding Sites, Base Sequence, Molecular Structure, Heparin, Protein Conformation, RNA Splicing, Molecular Sequence Data, Gene Amplification, DNA, Fibronectins, Chromosomes, Human, Pair 2, Sequence Homology, Nucleic Acid, Humans, Amino Acid Sequence, RNA, Messenger

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::624a39d6fc14a2111a67290631209d2b
https://pubmed.ncbi.nlm.nih.gov/3334363

المؤلفون: H. Craig Morton, Jd, Atkin, Rj, Owens, Jm, Woof

المصدر: Europe PubMed Central

مصطلحات موضوعية: Complement C1q, Cricetinae, Recombinant Fusion Proteins, Genetic Vectors, Serine Endopeptidases, Animals, Humans, CHO Cells, Transfection, Chromatography, Affinity, Cell Line, Immunoglobulin A, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::02202f970e7c7d0b7c5e51ce1e5106ed
http://europepmc.org/abstract/med/8409433

المؤلفون: Aj, Beavil, Rl, Beavil, Cm, Chan, Jp, Cook, Hannah Gould, Aj, Henry, Rj, Owens, Shi J, Bj, Sutton, Rj, Young

المصدر: Europe PubMed Central

مصطلحات موضوعية: Models, Molecular, Receptors, IgE, Cell Membrane, Animals, Humans, Amino Acid Sequence, Immunoglobulin E, Protein Structure, Secondary, Recombinant Proteins, Sequence Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::989828e6c91267152d567865c178983c
http://europepmc.org/abstract/med/8132102

المؤلفون: Clarke JD; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Douangamath A; Macromolecular Crystallography, Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom., Mikolajek H; Macromolecular Crystallography, Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom., Bonnet-Di Placido M; Immunogenetics, The Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, United Kingdom., Ren J; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Fry EE; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Stuart DI; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom., Hammond JA; Immunogenetics, The Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, United Kingdom., Owens RJ; The Division of Structural Biology, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom.

المصدر: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2024 Jul 01; Vol. 80 (Pt 7), pp. 154-163. Date of Electronic Publication: 2024 Jul 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Inc Country of Publication: United States NLM ID: 101620319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2053-230X (Electronic) Linking ISSN: 2053230X NLM ISO Abbreviation: Acta Crystallogr F Struct Biol Commun Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Heavy Chains*/chemistry , Immunoglobulin Light Chains*/chemistry , Immunoglobulin Light Chains*/genetics , Complementarity Determining Regions*/chemistry , Immunoglobulin Fab Fragments*/chemistry , Models, Molecular*, Animals ; Cattle ; Crystallography, X-Ray ; Amino Acid Sequence ; Protein Conformation

المؤلفون: Cornish K; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Huo J; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford , Oxford, UK., Jones L; Nuffield Department of Medicine, Pandemic Sciences Institute, University of Oxford , Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford , Oxford, UK., Sharma P; Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, UK., Thrush JW; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Abdelkarim S; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Kipar A; Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, UK.; Vetsuisse Faculty, Laboratory for Animal Model Pathology, Institute of Veterinary Pathology, University of Zurich , Zurich, Switzerland., Ramadurai S; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Weckener M; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Mikolajek H; Diamond Light Source Ltd, Harwell Science Campus , Didcot, UK., Liu S; James & Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford , Oxford, UK., Buckle I; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Bentley E; Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, UK., Kirby A; Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, UK., Han X; Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, UK., Laidlaw SM; Nuffield Department of Medicine, Pandemic Sciences Institute, University of Oxford , Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford , Oxford, UK., Hill M; James & Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford , Oxford, UK., Eyssen L; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Norman C; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Le Bas A; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., Clarke J; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK., James W; James & Lillian Martin Centre, Sir William Dunn School of Pathology, University of Oxford , Oxford, UK., Stewart JP; Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool, UK., Carroll M; Nuffield Department of Medicine, Pandemic Sciences Institute, University of Oxford , Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford , Oxford, UK., Naismith JH; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford , Oxford, UK., Owens RJ; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus , Didcot, UK.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford , Oxford, UK.

المصدر: Open biology [Open Biol] 2024 Jun; Vol. 14 (6), pp. 230252. Date of Electronic Publication: 2024 Jun 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society Pub Country of Publication: England NLM ID: 101580419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2046-2441 (Electronic) Linking ISSN: 20462441 NLM ISO Abbreviation: Open Biol Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/immunology , Single-Domain Antibodies*/immunology , Single-Domain Antibodies*/chemistry , Single-Domain Antibodies*/pharmacology , Antibodies, Neutralizing*/immunology , Antibodies, Neutralizing*/chemistry , COVID-19*/immunology , COVID-19*/virology , Spike Glycoprotein, Coronavirus*/immunology , Spike Glycoprotein, Coronavirus*/chemistry , Spike Glycoprotein, Coronavirus*/metabolism , Spike Glycoprotein, Coronavirus*/genetics , Antibodies, Viral*/immunology, Animals ; Humans ; Camelids, New World/immunology ; Epitopes/immunology ; Epitopes/chemistry ; Cricetinae ; Protein Binding ; Models, Molecular

SCR Organism: SARS-CoV-2 variants

المؤلفون: Rödström KEJ; Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.; Centre for Medicines Discovery, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK., Cloake A; Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, UK., Sörmann J; Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Baronina A; Centre for Medicines Discovery, University of Oxford, Oxford, UK., Smith KHM; Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK., Pike ACW; Centre for Medicines Discovery, University of Oxford, Oxford, UK., Ang J; Centre for Medicines Discovery, University of Oxford, Oxford, UK., Proks P; Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Schewe M; Institute of Physiology, Medical Faculty, Kiel University, Kiel, Germany., Holland-Kaye I; Department of Biochemistry, University of Oxford, Oxford, UK., Bushell SR; Centre for Medicines Discovery, University of Oxford, Oxford, UK., Elliott J; Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, UK., Pardon E; Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium.; VIB-VUB Center for Structural Biology, VIB, Brussels, Belgium., Baukrowitz T; Institute of Physiology, Medical Faculty, Kiel University, Kiel, Germany., Owens RJ; The Rosalind Franklin Institute, Harwell Campus, Didcot, UK.; Division of Structural Biology, University of Oxford, Oxford, UK., Newstead S; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK.; OXION Initiative in Ion Channels and Disease, University of Oxford, Oxford, UK., Steyaert J; Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium.; VIB-VUB Center for Structural Biology, VIB, Brussels, Belgium., Carpenter EP; Centre for Medicines Discovery, University of Oxford, Oxford, UK. lizcarpen1@gmail.com.; OXION Initiative in Ion Channels and Disease, University of Oxford, Oxford, UK. lizcarpen1@gmail.com., Tucker SJ; Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, UK. stephen.tucker@physics.ox.ac.uk.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK. stephen.tucker@physics.ox.ac.uk.; OXION Initiative in Ion Channels and Disease, University of Oxford, Oxford, UK. stephen.tucker@physics.ox.ac.uk.

المصدر: Nature communications [Nat Commun] 2024 May 16; Vol. 15 (1), pp. 4173. Date of Electronic Publication: 2024 May 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Potassium Channels, Tandem Pore Domain*/metabolism , Single-Domain Antibodies*/metabolism , Single-Domain Antibodies*/immunology , Single-Domain Antibodies*/chemistry, Humans ; Crystallography, X-Ray ; Animals ; Cryoelectron Microscopy ; HEK293 Cells ; Models, Molecular

المؤلفون: Eyssen LE; Structural Biology, Rosalind Franklin Institute, Didcot, OX11 0QX, UK., Ramadurai S; Structural Biology, Rosalind Franklin Institute, Didcot, OX11 0QX, UK., Abdelkarim S; Structural Biology, Rosalind Franklin Institute, Didcot, OX11 0QX, UK., Buckle I; Structural Biology, Rosalind Franklin Institute, Didcot, OX11 0QX, UK., Cornish K; Structural Biology, Rosalind Franklin Institute, Didcot, OX11 0QX, UK., Lin H; School of Pharmacy, University of Reading, Reading, RG6 6UB, UK., Jones AK; Centre for Dairy Research, University of Reading, Reading, RG2 9HY, UK., Stephens GJ; School of Pharmacy, University of Reading, Reading, RG6 6UB, UK., Owens RJ; Structural Biology, Rosalind Franklin Institute, Didcot, OX11 0QX, UK.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7BN, UK.

المصدر: Bio-protocol [Bio Protoc] 2024 Mar 20; Vol. 14 (6), pp. e4962. Date of Electronic Publication: 2024 Mar 20 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bio-protocol LLC Country of Publication: United States NLM ID: 101635102 Publication Model: eCollection Cited Medium: Internet ISSN: 2331-8325 (Electronic) Linking ISSN: 23318325 NLM ISO Abbreviation: Bio Protoc Subsets: PubMed not MEDLINE

المؤلفون: Mycroft-West CJ; The Rosalind Franklin Institute, Harwell Science & Innovation Campus, OX11 0QX, Didcot, UK., Abdelkarim S; The Rosalind Franklin Institute, Harwell Science & Innovation Campus, OX11 0QX, Didcot, UK., Duyvesteyn HME; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, OX3 7BN, Oxford, UK., Gandhi NS; Department of Computer Science and Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India.; School of Chemistry and Physics, Queensland University of Technology, QLD 4000, Brisbane, Australia.; Centre for Genomics and Personalised Health, Queensland University of Technology, Brisbane, QLD 4059, Australia., Skidmore MA; Centre for Glycoscience Research and Training, Keele University, ST5 5BG, Newcastle-Under-Lyme, UK., Owens RJ; The Rosalind Franklin Institute, Harwell Science & Innovation Campus, OX11 0QX, Didcot, UK.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, OX3 7BN, Oxford, UK., Wu L; The Rosalind Franklin Institute, Harwell Science & Innovation Campus, OX11 0QX, Didcot, UK. liang.wu@rfi.ac.uk.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, OX3 7BN, Oxford, UK. liang.wu@rfi.ac.uk.

المصدر: Nature communications [Nat Commun] 2024 Feb 13; Vol. 15 (1), pp. 1326. Date of Electronic Publication: 2024 Feb 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Heparitin Sulfate*/metabolism , Sulfotransferases*/metabolism, Humans ; Cryoelectron Microscopy ; Catalytic Domain ; Extracellular Matrix/metabolism