يعرض 1 - 10 نتائج من 63 نتيجة بحث عن '"RM Borzì"', وقت الاستعلام: 0.92s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis

    المؤلفون: MB Goldring, M Otero, DA Plumb, C Dragomir, M Favero, K El Hachem, K Hashimoto, HI Roach, E Olivotto, RM Borzì, KB Marcu

    المصدر: European Cells & Materials, Vol 21, Pp 202-220 (2011)

    مصطلحات موضوعية: Chondrocytes, gene regulation, cytokines, BMP signaling, collagens, Diseases of the musculoskeletal system, RC925-935, Orthopedic surgery, RD701-811

    وصف الملف: electronic resource

    Relation: http://www.ecmjournal.org/journal/papers/vol021/pdf/v021a16.pdf; https://doaj.org/toc/1473-2262

    URL الوصول: https://doaj.org/article/f10e4bfb4f6e45649c439f176540e21d

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  2. 2
    Hydroxytyrosol attenuates the hypomethylation of miR-9 promoters induced by oxidative stress

    المؤلفون: Stefania D’Adamo, S Cetrullo, Y Silvestri, M Minguzzi, RM Borzì, F Flamigni

    المساهمون: Stefania D’Adamo, S Cetrullo, Y Silvestri, M Minguzzi, RM Borzì, F Flamigni

    مصطلحات موضوعية: Hydroxytyrosol, microRNA-9, chondrocytes

    وصف الملف: ELETTRONICO

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______4094::3111c0a890bb219a5ef7d0386244937b
    http://hdl.handle.net/11585/645257

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  3. 3
    دورية أكاديمية
    NOTCH1: A Novel Player in the Molecular Crosstalk Underlying Articular Chondrocyte Protection by Oleuropein and Hydroxytyrosol.

    المؤلفون: Panichi V; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, Laboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy., Bissoli I; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, 40138 Bologna, Italy., D'Adamo S; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, 40138 Bologna, Italy., Flamigni F; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, 40138 Bologna, Italy., Cetrullo S; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, 40138 Bologna, Italy., Borzì RM; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.

    المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 18; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 18.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

    مواضيع طبية MeSH: Osteoarthritis*/metabolism , Cartilage, Articular*/metabolism, Humans ; Chondrocytes/metabolism ; Lipopolysaccharides/pharmacology ; Cells, Cultured ; Receptor, Notch1/genetics ; Receptor, Notch1/metabolism

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  4. 4
    دورية أكاديمية
    Small Extracellular Vesicles from Inflamed Adipose Derived Stromal Cells Enhance the NF- κ B-Dependent Inflammatory/Catabolic Environment of Osteoarthritis.

    المؤلفون: Cavallo C; Laboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., Merli G; Applied and Translational Research Center (ATRc), IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., Zini N; CNR Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', Unit of Bologna, Bologna 40136, Italy.; IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., D'Adamo S; Department of Medical and Surgical Sciences, University of Bologna, Bologna 40138, Italy.; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., Cattini L; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., Guescini M; Department of Biomolecular Science, University of Urbino Carlo Bo, Urbino 61029, Italy., Grigolo B; Laboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., Di Martino A; Clinica Ortopedica e Traumatologica 2, IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., Santi S; CNR Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', Unit of Bologna, Bologna 40136, Italy.; IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., Borzì RM; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy., Filardo G; Applied and Translational Research Center (ATRc), IRCCS Istituto Ortopedico Rizzoli, Bologna 40136, Italy.

    المصدر: Stem cells international [Stem Cells Int] 2022 Jul 18; Vol. 2022, pp. 9376338. Date of Electronic Publication: 2022 Jul 18 (Print Publication: 2022).

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Hindawi Country of Publication: United States NLM ID: 101535822 Publication Model: eCollection Cited Medium: Print ISSN: 1687-966X (Print) NLM ISO Abbreviation: Stem Cells Int Subsets: PubMed not MEDLINE

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  5. 5
    دورية أكاديمية
    Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes.

    المؤلفون: Minguzzi M; Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, 40138 Bologna, Italy., Panichi V; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, 40138 Bologna, Italy., D'Adamo S; Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, 40138 Bologna, Italy., Cetrullo S; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, 40138 Bologna, Italy., Cattini L; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy., Flamigni F; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, 40138 Bologna, Italy., Mariani E; Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, 40138 Bologna, Italy.; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy., Borzì RM; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.

    المصدر: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 05; Vol. 22 (21). Date of Electronic Publication: 2021 Nov 05.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

    مواضيع طبية MeSH: Chondrocytes/*pathology , Core Binding Factor Alpha 1 Subunit/*metabolism , Hypertrophy/*pathology , Matrix Metalloproteinase 13/*metabolism , Osteoarthritis/*pathology , Receptor, Notch1/*metabolism, Aged ; Cell Culture Techniques, Three Dimensional ; Cells, Cultured ; Chondrocytes/metabolism ; Female ; Humans ; Hypertrophy/etiology ; Hypertrophy/metabolism ; Male ; Osteoarthritis/etiology ; Osteoarthritis/metabolism ; Signal Transduction

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  6. 6
    دورية أكاديمية
    Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases.

    المؤلفون: Olivotto E; Laboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy., Minguzzi M; Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), Università di Bologna, Bologna, Italy., D'Adamo S; Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), Università di Bologna, Bologna, Italy., Astolfi A; Department of Translational Medicine, University of Ferrara, Ferrara, Italy., Santi S; Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', Unit of Bologna, CNR, Bologna, Italy.; IRCCS, Istituto Ortopedico Rizzoli, Bologna, Italy., Uguccioni M; Institute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Marcu KB; Departments of Biochemistry and Cell Biology and Pathology, SUNY, Stony Brook, NY, USA., Borzì RM; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. rosamaria.borzi@ior.it.

    المصدر: Scientific reports [Sci Rep] 2021 Nov 04; Vol. 11 (1), pp. 21697. Date of Electronic Publication: 2021 Nov 04.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

    بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

    مواضيع طبية MeSH: I-kappa B Kinase/*metabolism , Interleukin-1beta/*metabolism , Monocytes/*metabolism, Cells, Cultured ; Chemokine CCL2/metabolism ; Chemokines/immunology ; Chemokines/metabolism ; Chemotaxis/physiology ; Chondrocytes/metabolism ; Female ; Humans ; I-kappa B Kinase/physiology ; Inflammation ; Interleukin-1beta/physiology ; Male ; Middle Aged ; NF-kappa B/metabolism ; Osteoarthritis/metabolism ; Phosphorylation ; Protein Serine-Threonine Kinases ; Signal Transduction/physiology ; Transcription Factor RelA

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  7. 7
    دورية أكاديمية
    Oxidative stress-induced DNA damage and repair in primary human osteoarthritis chondrocytes: focus on IKKα and the DNA Mismatch Repair System.

    المؤلفون: Neri S; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Immunorheumatology and Tissue Regeneration, Via di Barbiano 1/10, 40136, Bologna, Italy. Electronic address: simona.neri@ior.it., Guidotti S; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Immunorheumatology and Tissue Regeneration, Via di Barbiano 1/10, 40136, Bologna, Italy. Electronic address: sere.guidotti@gmail.com., Bini C; Department of Medical and Surgical Sciences, (DIMEC), Unit of Legal Medicine, University of Bologna, Via Irnerio, 49, 40126, Bologna, Italy. Electronic address: carla.bini@unibo.it., Pelotti S; Department of Medical and Surgical Sciences, (DIMEC), Unit of Legal Medicine, University of Bologna, Via Irnerio, 49, 40126, Bologna, Italy. Electronic address: susi.pelotti@unibo.it., D'Adamo S; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Immunorheumatology and Tissue Regeneration, Via di Barbiano 1/10, 40136, Bologna, Italy. Electronic address: stefania.dadamo@ior.it., Minguzzi M; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Immunorheumatology and Tissue Regeneration, Via di Barbiano 1/10, 40136, Bologna, Italy; Department of Medical and Surgical Sciences, Alma Mater Studiorum-Università di Bologna, Bologna, Italy. Electronic address: manuela.minguzzi@gmail.com., Platano D; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Immunorheumatology and Tissue Regeneration, Via di Barbiano 1/10, 40136, Bologna, Italy; Department of Medical and Surgical Sciences, Alma Mater Studiorum-Università di Bologna, Bologna, Italy. Electronic address: daniela.platano@gmail.com., Santi S; CNR Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', Unit of Bologna at IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy. Electronic address: santi@area.bo.cnr.it., Mariani E; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Immunorheumatology and Tissue Regeneration, Via di Barbiano 1/10, 40136, Bologna, Italy; Department of Medical and Surgical Sciences, Alma Mater Studiorum-Università di Bologna, Bologna, Italy. Electronic address: eminia.mariani@ior.it., Cattini L; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Immunorheumatology and Tissue Regeneration, Via di Barbiano 1/10, 40136, Bologna, Italy. Electronic address: luca.cattini@ior.it., Borzì RM; IRCCS Istituto Ortopedico Rizzoli, Laboratory of Immunorheumatology and Tissue Regeneration, Via di Barbiano 1/10, 40136, Bologna, Italy. Electronic address: rosamaria.borzi@ior.it.

    المصدر: Free radical biology & medicine [Free Radic Biol Med] 2021 Apr; Vol. 166, pp. 212-225. Date of Electronic Publication: 2021 Feb 23.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

    بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

    مواضيع طبية MeSH: Chondrocytes*/metabolism , Osteoarthritis*/genetics, DNA Damage ; DNA Mismatch Repair/genetics ; DNA Repair/genetics ; Humans ; Hydrogen Peroxide/pharmacology ; I-kappa B Kinase/genetics ; I-kappa B Kinase/metabolism ; Oxidative Stress/genetics

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  8. 8
    دورية أكاديمية
    Small Extracellular Vesicles from adipose derived stromal cells significantly attenuate in vitro the NF-κB dependent inflammatory/catabolic environment of osteoarthritis.

    المؤلفون: Cavallo C; Laboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy., Merli G; Applied and Translational Research Center (ATRc), IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy., Borzì RM; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy. rosamaria.borzi@ior.it., Zini N; CNR Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', Unit of Bologna, Via di Barbiano 1/10, 40136, Bologna, Italy.; IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy., D'Adamo S; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Guescini M; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy., Grigolo B; Laboratorio RAMSES, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy., Di Martino A; Clinica Ortopedica e Traumatologica 2, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy., Santi S; CNR Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza', Unit of Bologna, Via di Barbiano 1/10, 40136, Bologna, Italy.; IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy., Filardo G; Applied and Translational Research Center (ATRc), IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy.

    المصدر: Scientific reports [Sci Rep] 2021 Jan 13; Vol. 11 (1), pp. 1053. Date of Electronic Publication: 2021 Jan 13.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

    بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

    مواضيع طبية MeSH: Mesenchymal Stem Cell Transplantation*/methods , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/ultrastructure, Extracellular Vesicles/*transplantation , NF-kappa B/*metabolism , Osteoarthritis/*therapy, Aged ; Blotting, Western ; Chondrocytes/metabolism ; Female ; Humans ; Inflammation/metabolism ; Inflammation/therapy ; Male ; Microscopy, Electron, Transmission ; Middle Aged ; Osteoarthritis/metabolism ; Real-Time Polymerase Chain Reaction ; Synoviocytes/metabolism

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  9. 9
    دورية أكاديمية
    Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes.

    المؤلفون: D'Adamo S; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy; Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy. Electronic address: stefania.dadamo2@unibo.it., Cetrullo S; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy. Electronic address: silvia.cetrullo@unibo.it., Guidotti S; Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy. Electronic address: sere.guidotti@gmail.com., Silvestri Y; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy. Electronic address: ylenia.silvestri@gmail.com., Minguzzi M; Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy. Electronic address: manuela.minguzzi@gmail.com., Santi S; CNR-Institute of Molecular Genetics 'Luigi Luca Cavalli-Sforza'-Unit of Bologna, Bologna, Italy; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. Electronic address: spartaco.santi@cnr.it., Cattini L; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. Electronic address: luca.cattini@ior.it., Filardo G; Applied and Translational Research Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. Electronic address: ortho@gfilardo.com., Flamigni F; Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy. Electronic address: flavio.flamigni@unibo.it., Borzì RM; Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy. Electronic address: rosamaria.borzi@ior.it.

    المصدر: Free radical biology & medicine [Free Radic Biol Med] 2020 Jun; Vol. 153, pp. 159-172. Date of Electronic Publication: 2020 Apr 17.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

    بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

    مواضيع طبية MeSH: Chondrocytes* , Spermidine*/pharmacology, Autophagy ; Hydrogen Peroxide/toxicity ; Oxidative Stress

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  10. 10
    دورية أكاديمية
    Nutraceutical Activity in Osteoarthritis Biology: A Focus on the Nutrigenomic Role.

    المؤلفون: D'Adamo S; Department of Medical and Surgical Sciences, Alma Mater Studiorum - University of Bologna, 40126 Bologna, Italy.; Laboratory of Immunorheumatology and Tissue Regeneration, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy., Cetrullo S; Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum - University of Bologna, 40126 Bologna, Italy., Panichi V; Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum - University of Bologna, 40126 Bologna, Italy., Mariani E; Department of Medical and Surgical Sciences, Alma Mater Studiorum - University of Bologna, 40126 Bologna, Italy.; Laboratory of Immunorheumatology and Tissue Regeneration, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy., Flamigni F; Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum - University of Bologna, 40126 Bologna, Italy., Borzì RM; Laboratory of Immunorheumatology and Tissue Regeneration, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.

    المصدر: Cells [Cells] 2020 May 16; Vol. 9 (5). Date of Electronic Publication: 2020 May 16.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

    بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

    مواضيع طبية MeSH: Dietary Supplements* , Nutrigenomics*, Osteoarthritis/*genetics , Osteoarthritis/*therapy, Animals ; Humans ; Osteoarthritis/physiopathology ; Phytochemicals/therapeutic use ; Treatment Outcome

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