المؤلفون: Tambe, Akshay, East-Seletsky, Alexandra, Knott, Gavin J, Doudna, Jennifer A, O’Connell, Mitchell R

المصدر: Cell Reports. 24(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, CRISPR-Associated Proteins, CRISPR-Cas Systems, Carrier Proteins, Endonucleases, Humans, RNA, Guide, Kinetoplastida, C2c2, CRISPR-Cas systems, Cas13, Cas13a, RNA biology, RNA specificity, Medical Physiology, Biological sciences

URL الوصول: https://escholarship.org/uc/item/1mv316hn

المؤلفون: Jain, Niyati, Lin, Hsuan-Chun, Morgan, Christopher E., Harris, Michael E., Tolbert, Blanton S.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2017 Feb . 114(9), 2206-2211.

URL الوصول: https://www.jstor.org/stable/26479469

المؤلفون: Yong Jung, Vasant Honavar, Drena Dobbs, Yasser EL-Manzalawy

المصدر: Proteins

مصطلحات موضوعية: Models, Molecular, protein‐RNA interactions, Protein Conformation, Protein Data Bank (RCSB PDB), Computational biology, Biology, Biochemistry, 03 medical and health sciences, protein‐RNA Interface prediction, Sequence Analysis, Protein, Structural Biology, Gene expression, Amino Acid Sequence, RNA‐specificity metric, Binding site, Structural motif, Molecular Biology, Research Articles, 030304 developmental biology, 0303 health sciences, Binding Sites, Base Sequence, 030302 biochemistry & molecular biology, Computational Biology, Proteins, RNA-Binding Proteins, RNA, performance evaluation, RNA Sequence, Metric (mathematics), RNA-Binding Motifs, Critical assessment, partner‐specific protein‐RNA binding, Software, Research Article, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0b02fe84d81115432d2ddb79371f38
https://doi.org/10.1002/prot.25639

المؤلفون: Gavin J. Knott, Jennifer A. Doudna, Mitchell R. O’Connell, Akshay Tambe, Alexandra East-Seletsky

المصدر: Cell reports, vol 24, iss 4
Tambe, Akshay; East-Seletsky, Alexandra; Knott, Gavin J; Doudna, Jennifer A; & O'Connell, Mitchell R. (2018). RNA Binding and HEPN-Nuclease Activation Are Decoupled in CRISPR-Cas13a.. Cell reports, 24(4), 1025-1036. doi: 10.1016/j.celrep.2018.06.105. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1mv316hn

مصطلحات موضوعية: 0301 basic medicine, CRISPR-Cas systems, Cas13a, Base pair, RNA biology, Medical Physiology, CRISPR-Associated Proteins, Computational biology, Cleavage (embryo), Article, General Biochemistry, Genetics and Molecular Biology, Rna regulation, RNA specificity, 03 medical and health sciences, Genetics, Humans, CRISPR, Nucleotide, chemistry.chemical_classification, Nuclease, Cas13, biology, RNA, Endonucleases, 030104 developmental biology, Enzyme, chemistry, C2c2, biology.protein, Biochemistry and Cell Biology, CRISPR-Cas Systems, Carrier Proteins, Guide, RNA, Guide, Kinetoplastida

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c93e2f5ee551b818f53e419c7d940a
https://doi.org/10.1016/j.celrep.2018.06.105

المؤلفون: Luc Ponchon, Bruno Sargueil, Fatima Benattia, Nathalie Ulryck, Nathalie Chamond, Melissa Ameur, Grégoire de Bisschop

المساهمون: Cibles Thérapeutiques et conception de médicaments (CiTCoM - UMR 8038), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5), Laboratoire de cristallographie et RMN biologiques (LCRB - UMR 8015), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5), Institut de biochimie et biophysique moléculaire et cellulaire (IBBMC), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Biochimie
Biochimie, Elsevier, 2019, 164, pp.83-94. ⟨10.1016/j.biochi.2019.03.008⟩

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], HIV Infections, Biochemistry, Substrate Specificity, DEAD-box RNA Helicases, 03 medical and health sciences, RNA specificity, Transcription (biology), ATPase, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Guide RNA, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], ComputingMilieux_MISCELLANEOUS, Ribonucleoprotein, chemistry.chemical_classification, 030102 biochemistry & molecular biology, biology, RNA, Helicase, General Medicine, Biochemical Activity, Cell biology, Kinetics, 030104 developmental biology, Enzyme, chemistry, Cytoplasm, biological substrate, biology.protein, HIV-1, DDX3X, Protein Binding, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199028142125480dd108d473d70423b8
https://pubmed.ncbi.nlm.nih.gov/30910425

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